Search clinical trials for: KYN-5356

Total 254 results

Kynexis B.V.
Parexel

Recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of KYN-5356 in Healthy Subjects Aged 18 to 55 Years

Schizophrenia | Cognitive Dysfunction

United States
Kyowa Kirin Co., Ltd.

Completed

A Study of Single and Multiple Doses of KW-6356 in Healthy Subjects

Parkinson's Disease

Japan
Ikena Oncology
Bristol-Myers Squibb

Completed

A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma

Neoplasms | Neoplasm Metastasis | Solid Tumor | Metastatic Cancer | Bladder Cancer | Advanced Solid Tumor | Advanced Cancer | Urothelial Carcinoma Bladder | Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Solid Tumor, Adult | Bladder Disease | Solid Carcinoma | Neoplasm Malignant | Neoplasm, Bladder | Locally Advanced... and other conditions

United States
Assembly Biosciences

Not yet recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes

Recurrent Genital Herpes Simplex Type 2

New Zealand
Kyowa Kirin, Inc.

Completed

Single-dose Study to Investigate the Plasma PK of KW-6356 and Its Major Metabolite

Hepatic Impairment

United States
Kyowa Kirin, Inc.

Completed

Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-KW-6356

Healthy Male Subjects

United States
VistaGen Therapeutics, Inc.
National Institute on Drug Abuse (NIDA); Cato Research

Completed

Safety, Tolerability and Pharmacokinetics of Multiple Doses of AV-101 in Healthy Volunteers

Neuropathic Pain

United States
Columbia University
National Institute on Aging (NIA)

Withdrawn

TAU PET Imaging in Northern Manhattan Study of Metabolism and Mind (TAUPET)

Diabetes Mellitus | Alzheimer Dementia

United States
Shin Poong Pharmaceutical Co. Ltd.

Terminated

A Phase I Study to Evaluate Safety and Pharmacokinetics of Escalating Single Doses and Multiple Doses of SP-8356

Ischemic Stroke | Atherosclerosis

United Kingdom
Synthetic Biologics Inc.

Completed

A Study of the Effect of SYN-010 on Subjects With IBS-C

Irritable Bowel Syndrome With Constipation (IBS-C)

United States
National Institute of Mental Health (NIMH)

Completed

Antidepressant Effects of the Glycine Receptor Antagonist AV-101 (4-chlorokynurenine) in Major Depressive Disorder

Major Depression

United States
Kyowa Kirin Co., Ltd.

Completed

A Study of KW-6356 in Subjects With Early Parkinson's Disease

Parkinson's Disease

Japan
Chang Gung Memorial Hospital

Completed

Biodistribution, Pharmacokinetics, and Safety of F-18 THK-5351 PET in Alzheimer's Disease Patients and Healthy Subjects.(Positron Emission Tomograph ) (PET)

Alzheimer's Disease
Synthetic Biologics Inc.

Completed

A Single-Dose, Open-Label, Study to Evaluate the Sustainability of the Effects of SYN-010 in Patients With IBS-C

Irritable Bowel Syndrome With Constipation (IBS-C)

United States
Kineta Inc.
Wellcome Trust

Completed

Multiple Ascending Oral Dose 14-Day Trial of LHF-535 in Healthy Participants

Healthy

Australia
Chang Gung Memorial Hospital

Recruiting

The Influence of Sequential Tau Protein and Amyloid Plaque Imaging Changes on Stroke Prognosis and Cognitive Outcome

Post-stroke Dementia, Vascular Mild Cognitive Impairment

Taiwan
Jae Seung Kim
Samsung Medical Center; Korea Health Industry Development Institute

Completed

[18F]THK-5351 Positron Emission Computed Tomography Study of Normal, Mild Cognitive Impairment, Alzheimer's Disease and Other Neurodegenerative Disease

Neurodegenerative Diseases | Mild Cognitive Impairment | Alzheimer's Disease

Korea, Republic of
Asan Foundation

Completed

A Phase I [18F]THK-5351 Positron Emission Tomography Study in Healthy Subjects and Alzheimer's Disease

Alzheimer Disease

Korea, Republic of
Biocodex

Recruiting

Effect of Ultra-gyn® on Vulvovaginal Candidiasis

Vulvovaginal Candidiasis, Genital

Mauritius
Kanyos Bio, Inc., a wholly-owned subsidiary of...

Completed

Assessment of KAN-101 in Celiac Disease (ACeD)

Celiac Disease

United States
Lyndra Inc.

Completed

Study to Evaluate Safety/Duration in Stomach of Extended Release Capsules in Healthy Adults

Healthy | Gastric Retention

Australia
Kinnate Biopharma

Active, not recruiting

A Study to Evaluate KIN-3248 in Participants With Advanced Tumors Harboring FGFR2 and//or FGFR3 Gene Alterations

Intrahepatic Cholangiocarcinoma | Urothelial Carcinoma | Solid Tumor, Adult

United States, Korea, Republic of, Taiwan, China, Denmark, Spain
Duke University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

KAN-DO: A Family-based Intervention to Prevent Childhood Obesity (KAN-DO)

Obesity | Prevention & Control | Postpartum Period

United States
CND Life Sciences

Recruiting

The Syn-Sleep Study

REM Sleep Behavior Disorder (iRBD)

United States
University of California, Irvine
Wakunaga Pharmaceutical Co., Ltd.

Withdrawn

Effects of Probiotics in Patients With Ulcerative Colitis

Ulcerative Colitis

United States
Synthetic Biologics Inc.

Completed

A Study of SYN-004 for the Prevention of C.Diff in Patients With a LRTI

Clostridium Infections | Clostridium Difficile

United States, Bulgaria, Canada, Hungary, Poland, Romania, Serbia
University of Florida
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Alcohol Monitor Validation

Human Immunodeficiency Virus (HIV)

United States
Wake Forest University Health Sciences
Procter and Gamble

Active, not recruiting

Shaving Satisfaction in Males With Skin Irritation From Shaving

Pseudofolliculitis Barbae

United States
Karo Pharma AB

Completed

Multi-Gyn FloraFem Study for Treatment of Vulvo Vaginal Candidiasis Symptoms

Vulvovaginal Candidiasis

Poland
Karo Pharma AB

Completed

Single Arm Study of Multi-Gyn ActiGel Plus for Treatment of Bacterial Vaginosis

Bacterial Vaginosis

Poland
Sumitomo Pharma America, Inc.

Recruiting

A Study of DSP-5336 in Relapsed/Refractory AML/ ALL With or Without MLL Rearrangement or NPM1 Mutation

Leukemia, Myeloid, Acute | Leukemia, Lymphocytic, Acute

Japan, United States
Synthetic Biologics Inc.
Spaulding Clinical Research LLC

Completed

Multiple Ascending Dose Study to Assess the Pharmacokinetics, Safety, and Tolerability of Orally Administered SYN 020

Enteritis Caused by Radiation

United States
Boston Pharmaceuticals

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Effects of Repeat Topical Application of BOS-356 in Subjects With Moderate to Severe Acne Vulgaris

Moderate to Severe Acne Vulgaris

United States, Canada
Kinnate Biopharma

Recruiting

A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors

Melanoma | Non-small Cell Lung Cancer | Solid Tumor, Adult

United States, Australia, France, Spain, Taiwan, Korea, Republic of, China, Netherlands
Chang Gung Memorial Hospital

Completed

The Aging Brain and Cognition: Contribution of Vascular Injury, Amyloid Plaque and Tau Protein to Cognitive Dysfunction After Stroke

Post-stroke Dementia | Vascular Mild Cognitive Impairment

Taiwan
Boehringer Ingelheim

Completed

Relative Bioavailability of 1 mg and 10 mg BI 1356 BS as Powder in the Bottle (PIB) to 1 mg and 10 mg BI 1356 BS as Tablets as Single Oral Administration in Healthy Male Volunteers Including the Influence of Food on the Bioavailability of 10 mg BI 1356 BS

Healthy
EDAP TMS S.A.

Unknown

Dynamic Focusing Evaluation for Prostate Cancer Treatment (FOC/DYN)

Cancer of Prostate

France
Chang Gung Memorial Hospital

Completed

Novel Neuroimage Study in Tauopathies With Parkinsonism

Parkinsonism

Taiwan
Yale University

Completed

Switching to Potential Reduced Exposure Products in Adult Smokers (ZYN)

Tobacco Use Disorder | Carcinogenesis | Harm Reduction | Smoking Behaviors | Oral Nicotine Pouch Use | Toxic Effect of Tobacco and Nicotine

United States
Chang Gung Memorial Hospital

Completed

Pathophysiology of Neurodegeneration in Late-life Depression (AV45+THK)

Major Depressive Disorder

Taiwan
William Charles Kreisl
National Institute on Aging (NIA)

Terminated

Imaging Tau in Alzheimer's Disease and Normal Aging

Alzheimer's Disease

United States
Stanford University

Not yet recruiting

Study of KYV-101 Anti-CD19 CAR T Therapy in Adult Dermatomyositis

Dermatomyositis

United States
Duke University
National Institute of Mental Health (NIMH); Louisiana State University Health...

Enrolling by invitation

Start the Conversation: Evaluating Implementation of a Multi-level PrEP Initiative for Black Cisgender Women in Nola

HIV Infections | Preexposure Prophylaxis

United States
Cook Group Incorporated

Completed

FORMAT Clinical Study

Symptomatic Vascular Disease of the Iliac Arteries

United States
Abbott Medical Devices

Completed

Prevention of Atrial Fibrillation by Optimized Overdrive Stimulation (PAFOS)

Atrial Fibrillation | Bradycardia

Germany
Science and Research Centre Koper
University of Michigan

Recruiting

Cognitive and Motor Benefits of Standing (KOGIS)

Pain, Acute | Work-Related Condition | Muscle Tone Abnormalities | Sensory Deficit

Slovenia
Michigan State University
National Institute of Nursing Research (NINR)

Completed

Kin KeeperSM: Reducing Disparities Through Cancer Literacy and Screening (KinKeeper)

Cervical Cancer | Breast Cancer

United States
Boehringer Ingelheim

Completed

Safety and Efficacy of Linagliptin (BI 1356) Plus Metformin in Type 2 Diabetes, Factorial Design

Diabetes Mellitus, Type 2

Canada, Croatia, Estonia, France, Germany, India, Lithuania, Mexico, Netherlands, Romania, Russian Federation, Sweden, Tunisia, Ukraine
Kyowa Kirin Co., Ltd.

Completed

A Study of KW-6356 in Patients With Parkinson's Disease on Treatment With Levodopa-containing Preparations

Parkinson's Disease

Japan
Synthetic Biologics Inc.
Spaulding Clinical Research LLC

Completed

Pharmacokinetics, Safety, and Tolerability of SYN-020

Enteritis Caused by Radiation (Disorder)

United States

Search clinical trials for: KYN-5356

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