Search clinical trials for: L-(11C) methionine

Total 4697 results

Merck Sharp & Dohme LLC

Completed

[11C]MK-6884 Positron Emission Tomography (PET) Tracer Validation Trial (MK-6884-001)

Alzheimer's Disease
Alkermes, Inc.
University Medical Center Groningen; Amsterdam UMC, location VUmc; QPS Netherlands...

Completed

A Non-therapeutic Feasibility Study of the Radioligand [11C]-UCB-J for Imaging Synaptic Density

Healthy | Alzheimer Disease

Netherlands
National Institute of Mental Health (NIMH)

Completed

PET Imaging of Brain Amyloid Using [11C]MeS-IMPY

Healthy | Alzheimer's Disease

United States
Yale University
National Institute on Drug Abuse (NIDA)

Recruiting

OMAR Opioid Use Disorder

Opioid Use Disorder | Healthy Control

United States
Yale University
National Institute on Drug Abuse (NIDA); National Institute of Mental Health...

Recruiting

Imaging mGluR5 and Synaptic Density in Psychiatric Disorders

Healthy | Bipolar Disorder | Major Depressive Disorder

United States
Yale University
National Institute of Neurological Disorders and Stroke (NINDS)

Not yet recruiting

Imaging Depression in Parkinson's Disease

Parkinson's Disease | Major Depressive Disorder
University of Pennsylvania

Recruiting

Neuroinflammation Imaging in AD

Alzheimer Disease | Healthy Volunteer

United States
Hoffmann-La Roche

Completed

Open Label, Adaptive, Parallel Group PET Study Using RO7017773 And [11C] RO15-4513

Autism Spectrum Disorder

United Kingdom
AstraZeneca
Karolinska Institutet, Quintiles IMS

Completed

AZD1390 Administration of a Microdose [11C]AZD1390 to Healthy Volunteers

Healthy Volunteer Male Subjects

Sweden
AstraZeneca

Completed

Positron Emission Tomography (PET) Study With [11C]AZ12713580 to Determine Central mGluR5 Receptor Occupancy of AZD2066 (PET)

Healthy

Sweden
National Institute of Diabetes and Digestive and...

Terminated

SAMe to Treat Biliary Cirrhosis Symptoms

Liver Cirrhosis, Biliary

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of [11C]JNJ-42491293, a Possible PET Ligand for the mGlu2 Receptor, in Healthy Adult Volunteers

Healthy
Patrick Lao
National Institute on Aging (NIA)

Recruiting

Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease (ADVISe)

Alzheimer Disease

United States
Washington University School of Medicine
The Foundation for Barnes-Jewish Hospital

Completed

Sex and Obesity: Effects on Heart Failure Study

Heart Failure | Obesity

United States
The University of Texas Health Science Center,...

Recruiting

Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: A Dimensional Approach

Neuropsychiatric Syndromes

United States
Yale University
National Institute on Drug Abuse (NIDA)

Recruiting

SV2A in Older Adults

Cannabis Use

United States
Massachusetts General Hospital

Recruiting

Imaging Histone Deacetylase in the Heart

Diabetes | Aortic Valve Stenosis | Heart Failure With Normal Ejection Fraction | Left Ventricular Hypertrophy

United States
National Institute of Mental Health (NIMH)
University of Maryland

Completed

PET Imaging of Cyclooxygenase-2 in Multiple Sclerosis

Multiple Sclerosis

United States
Imperial College London

Recruiting

Quantifying 18kDa TSPO Expression in the Lung in Pulmonary Artery Hypertension (PAH)

Healthy | Pulmonary Arterial Hypertension

United Kingdom
Akiva Mintz

Recruiting

Exploratory Evaluation of [11C]-NOP46

Chronic Pain

United States
IRCCS San Raffaele

Completed

PET Study With 11 C-PIB to Evaluate Amyloid Protein Deposits in Mild Cognitive Disorder, Alzheimer's Disease and Early Frontotemporal Degeneration.

Alzheimer Disease
AstraZeneca

Completed

A PET Study to Determine Biodistribution and Binding Characteristics of [11C]AZ14132516 in Healthy Participants

Healthy Volunteers

Sweden
Assistance Publique - Hôpitaux de Paris

Completed

Administration of Methionine in Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS Gene. (MetPAP)

Pulmonary Alveolar Proteinosis | Mutation Ala393Thr of the MARS Gene | mutationSer567Leu of the MARS Gene

France
Meridian Bioscience, Inc.
Virginia Commonwealth University; Asian Institute of Gastroenterology, Hyderabad...

Completed

BreathID® Test: A Non-invasive Modality to Detect Pancreatic Exocrine Insufficiency

Healthy Volunteers | Chronic Pancreatitis

India
University of Manitoba
Micropharma Limited

Completed

Efficacy of Two Yogurt Formulations in Healthy Humans (MPH)

Healthy
Huang, Jeannie, M.D.

Completed

Evaluation of S-adenosyl Methionine (SAM-e) for Recurrent Abdominal Pain in Children

Abdominal Pain

United States
IRCCS San Raffaele

Completed

Prognostic Values of PET Examination With 11 C-Fe_CIT With Voxel-based Analysis Method in Patients With Sporadic Parkonson's Disease and Parkinsonisms (Prot.PD-diagn).

Parkinson Disease
Bristol-Myers Squibb

Completed

A Study to Evaluate the Safety, Tolerability, Kinetics, Biodistribution and Repeatability of 11C-BMS-986196 After Intravenous (IV) Administration in Healthy Participants and After Repeat IV Administration in Participants With Multiple Sclerosis

Multiple Sclerosis (MS)

United States, United Kingdom
National University Hospital, Singapore

Unknown

Evaluation of 11C-acetate PET Imaging as a Novel Approach to Detecting Pathology in Pulmonary TB

Tuberculosis, Pulmonary

Singapore
New Approaches to Neuroblastoma Therapy Consortium
National Cancer Institute (NCI)

Completed

N99-02: Melphalan and Buthionine Sulfoximine (BSO)

Neuroblastoma

Canada, United States
Washington University School of Medicine

Recruiting

Investigation of Inflammation in Alzheimer's Disease and Related Dementias (ADRD) Using [11C]-CS1P1

Alzheimer Disease

United States
Davidzon, Guido, M.D.
Weston Havens Foundation

Recruiting

Imaging Synapses With [11C] UCB-J in the Human Brain

Schizophrenia

United States
Juliano Casonatto

Unknown

Impact of Citrulline and Arginine Supplementation on the Post-exercise Hypotension (PEH) (PEH)

Hypertension

Brazil
Food and Nutrition Research Institute, Philippines
Mahidol University; International Atomic Energy Agency

Not yet recruiting

Metabolic Availability of Methionine in Mung Beans

Healthy Women of Child Bearing Potential

Philippines
Shanghai Zhongshan Hospital

Recruiting

Anti-PD-1/PD-L1 Antibodies Plus S-adenosyl-methionine Treatment in Patients With Advanced-Stage HCC

Hepatocellular Carcinoma

China
University of Aarhus

Completed

Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CT

Primary Sclerosing Cholangitis | Cholestasis | Primary Biliary Cirrhosis

Denmark
Johns Hopkins University
Precision Molecular

Terminated

Study of [11C]CPPC to Assess the Safety and Tolerability in Patients With ALS

Amyotrophic Lateral Sclerosis

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
United States Department of Defense

Active, not recruiting

Linaclotide in Treating Patients With Stages 0-3 Colorectal Cancer

Colorectal Adenoma | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC v8 | Stage IIIC Colorectal Cancer AJCC v8 | Stage 0 Colorectal Cancer AJCC v8 | Stage I Colorectal Cancer AJCC v8 | Stage II Colorectal Cancer AJCC v8 | Stage IIA Colorectal... and other conditions

United States
Massachusetts General Hospital
Genentech, Inc.

Unknown

Effect of Ocrelizumab on Neuroinflammation in Multiple Sclerosis as Measured by 11C-PBR28 MR-PET Imaging of Microglia Activation

Multiple Sclerosis
AstraZeneca

Completed

Positron Emission Tomography (PET) Study With [18F]AZD4694 and [11C]AZD2184, Candidate PET Ligands for Aβ Amyloid (PET)

Alzheimer's Disease

Sweden
St. Jude Children's Research Hospital

Active, not recruiting

A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or Observation After Radical Resection

Craniopharyngioma

United States
Marc-André Maheu-Cadotte

Completed

Development of an Educational Video Game to Improve Nursing Students' Reasoning With Acute Heart Failure Patients

Heart Failure | Motivation

Canada
Peking Union Medical College Hospital

Recruiting

[18F]Florbetazine ([18F]92) for Beta Amyloid PET Imaging in Alzheimer's Disease

Alzheimer's Disease

China
Universitaire Ziekenhuizen KU Leuven
CHDI Foundation, Inc.

Not yet recruiting

Comparison Between [11C]UCB-J and [18F]SynVest-1 PET in HD.

Huntington Disease

Belgium
Christine Elizabeth Edmonds

Withdrawn

Imaging With [11C]Martinostat in Breast Cancer

Breast Cancer

United States
National Institute of Mental Health (NIMH)

Completed

PET Imaging of Brain 5-HT(1A) Receptors Using [(11)C](-)-RWAY

Healthy Volunteers

United States
AstraZeneca

Completed

Evaluation of Histamine H3 Receptor Radioligand [11C]AZ12807110 and Histamine H3 Receptor Occupancy of AZD5213 After Oral Administration

Brain Distribution of [11C]AZ12807110 and AZD5213

Sweden
Johns Hopkins University
United States Department of Defense

Not yet recruiting

Study of [11C]CPPC as a Clinical PET Radioligand Biomarker of Microglial Activation in ALS

ALS
National Institute of Mental Health (NIMH)

Recruiting

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

Parkinson's Disease | Dementia | ALS | Alzheimer's Disease

United States
Zhongshan Hospital Xiamen University

Recruiting

Type 2 Deiodinase Gene Polymorphism and the Treatment of Hypothyroidism Caused by Thyroidectomy in Thyroid Cancer Patients.

Hypothyroidism | Thyroid Cancer, Papillary

China

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