Search clinical trials for: LentiGlobin BB305 Drug Product for SCD

Total 209 results

bluebird bio

Completed

A Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell Disease

Sickle Cell Disease | Beta-Thalassemia Major

France
bluebird bio

Completed

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia

Beta-Thalassemia

United States, Germany, United Kingdom, France, Greece, Italy
bluebird bio

Completed

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

Beta-Thalassemia

France, United Kingdom, United States, Thailand, Italy, Germany
bluebird bio

Completed

A Study Evaluating the Safety and Efficacy of the LentiGlobin BB305 Drug Product in β-Thalassemia Major Participants

β-thalassemia Major

United States, Australia, Thailand
bluebird bio

Recruiting

A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease

Sickle Cell Disease

United States
bluebird bio

Completed

A Study Evaluating the Safety and Efficacy of bb1111 in Severe Sickle Cell Disease

Sickle Cell Disease

United States
Pierre Fabre Medicament

Completed

Exploratory Study in the Relief of Drug-induced Xerostomia Associated With Hyposialia

Drug-induced Xerostomia

Germany
University of Arkansas

Completed

Effects of Nutritional Supplementation (Product 4808) on Acute Skeletal Muscle Protein Synthesis in Cancer Patients

Cancer

United States
Swedish Match AB

Completed

Controlled Study of the Ability of a Smokefree Tobacco Product to Increase the Quit Rate Among Cigarette Smokers

Cigarette Smoking

United States
National Institute of Allergy and Infectious Diseases...
Atopic Dermatitis Research Network

Terminated

Targeted Investigation of Microbiome Elimination (TIME-1)

Atopic Dermatitis

United States
Ain Shams University
Cairo University

Completed

Pharmacokinetics of Ledipasvir/Sofosbuvir in Hepatitis C Virus-Infected Children With Hematological Malignancy

Hepatitis C, Chronic | Hematologic Malignancy

Egypt
University of Calgary
Bayer

Unknown

Upfront Combination Pulmonary Arterial Hypertension Therapy

Pulmonary Hypertension

Canada
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Not yet recruiting

A Study of FDA022-BB05 in Subjects With Advanced Solid Malignant Tumors

Advanced Solid Tumors
University of Aarhus
Arla Foods

Recruiting

Effects of Intact and Disrupted Milk Fat Globule Membrane on Postprandial Metabolic Response to High-fat Dairy in Healthy Individuals

Postprandial Lipid Metabolism

Denmark
University of Southampton
University of Nottingham; Norfolk and Norwich University Hospitals NHS Foundation... and other collaborators

Not yet recruiting

Cellulitis Optimal Antibiotic Treatment (COAT)

Cellulitis of Leg
Washington University School of Medicine
University of North Carolina, Chapel Hill; Nigerian Institute of Medical Research

Recruiting

Actions For Collaborative Community Engaged Strategies for HPV

HPV | Stigma

Nigeria
Nutricia Research
INQUIS Clinical Research Ltd.

Completed

Assessment of the Glycemic Responses to Nutritional Products (GLIN#1)

Glycemic Response

Canada
University of Florida

Not yet recruiting

RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)

Recurrent Glioblastoma

United States
ImmunityBio, Inc.

Terminated

THEMBA II T-Cell Vaccine: Vaccination With saRNA COVID-19 Vaccines

COVID-19

South Africa
Boston University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Non-Communicable Diseases and Antiretroviral Therapy Outcomes in the RapIT Study Population (RapIT-NCD)

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Antiretroviral Therapy, Highly Active

South Africa
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

A Clinical Trial for the Treatment of Carbapenem Resistant Gram-negative Bacterial Infection With Colistimethate Sodium for Injection

Mental Health Issue

China
Università degli Studi di Sassari

Completed

Effect of a Self-adhering Material in Dental Hypersensitivity

Dentin Sensitivity | Xerostomia

Italy
Fresenius Kabi USA, LLC

Completed

Bioequivalence of Fresenius Kabi USA, LLC Glucagon for SC Injection Compared to Glucagon for Injection (Bedford Laboratories)

Hypoglycemia

United States
Johns Hopkins Bloomberg School of Public Health
United States Agency for International Development (USAID); Population Council and other collaborators

Completed

Project YES! Youth Engaging for Success (Project YES!)

HIV/AIDS

Zambia
Vireo Health

Completed

Do Discounted Vouchers for Medical Cannabis Reduce Opioid Use in Adults With Pain (ReLeaf-V)

Chronic Pain | Opioid Use | Marijuana

United States
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co....

Completed

Bioequivalence of Amphotericin B Liposome for Injection

Bioequivalence

China
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co....

Completed

A Pilot Bioequivalence Study Between Amphotericin B Liposome for Injection and AmBisome® in Healthy Subjects

Bioequivalence

China
Universidad San Francisco de Quito
Biocodex; Universidad Tecnológica Equinoccial

Completed

Effect of Probiotics on the Fecal Resistome During Helicobacter Pylori Eradication Therapy

Gut Resistome
Ruijin Hospital

Unknown

Arsenic Trioxide in Recurrent and Metastatic Ovarian Cancer and Endometrial Cancer With P53 Mutation

Ovarian Cancer | Endometrial Cancer

China
Sanford Health

Completed

Study of Topical Superoxide Dismutase to Treat Radiation Induced Fibrosis (Sodermix)

Radiation Induced Fibrosis to the Head and Neck

United States
Weill Medical College of Cornell University
National Institute on Aging (NIA)

Not yet recruiting

Center for Research and Education on Aging and Technology Enhancement - CREATE V

Mild Cognitive Impairment

United States
Hospital General Universitario de Valencia

Not yet recruiting

Transcriptomic Profile of Patients Treated With Different Modalities of Spinal Cord Stimulation (SCS-OMICS)

Failed Back Surgery Syndrome | Spinal Cord Stimulation | Genetic Change

Spain
China Academy of Chinese Medical Sciences
Beijing Tiantan Hospital; Dongzhimen Hospital, Beijing

Completed

Efficiency Study of Traditional Chinese Medicine (TCM) Versus Western Medicine (WM) on Ischemic Stroke

Stroke

China
Universidad Católica San Antonio de Murcia
Evonik Operations GmbH

Completed

Efficacy of a Dietary Ingredient Combination With Omega-3 for Joint Function (7DHA)

Joint Function Disorder

Spain
Danone Research

Completed

Effect of 4-week Oral Administration of a Fermented Dairy Product Containing Lactobacillus Rhamnosus CNCM I-3690, on Subjective State Anxiety Levels in Healthy Women Undergoing Academic Stress. (Tara)

Anxious Healthy Subjects

Belgium
Emory University
Bioverativ Therapeutics Inc.

Completed

Extended Half Life Factor (EHF) Products For Heavy Menstrual Bleeding in Hemophilia Carriers

Hemophilia | Menstrual Flow Excessive

United States
Clover Biopharmaceuticals AUS Pty Ltd
International Vaccine Institute; Coalition for Epidemic Preparedness Innovations

Completed

A Controlled Phase 2/3 Study of Adjuvanted Recombinant SARS-CoV-2 Trimeric S-protein Vaccine (SCB-2019) for the Prevention of COVID-19 (SCB-2019)

COVID-19

Colombia, Belgium, Brazil, Philippines, South Africa
University of Arkansas

Recruiting

Nutritional Therapy for Delirium in Elderly Hospitalized Subjects

Subacute Delirium

United States
Tel-Aviv Sourasky Medical Center

Completed

Conventional Photodynamic Therapy Versus Daylight Photodynamic Therapy for The Treatment of Acne Vulgaris

Acne Vulgaris

Israel
Organon and Co

Completed

Efficacy and Safety Study of a Single Injection of SCH 900962 Versus Daily recFSH Injections in Women Undergoing Controlled Ovarian Stimulation (Study P06029) (PURSUE)

Infertility
Encube Ethicals Pvt. Ltd.
CBCC Global Research

Completed

Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis

Actinic Keratoses

United States
King's College London

Unknown

The Relationship of Essential Fatty Acids to Adult ADHD: The OCEAN Study (Oils and Cognitive Effects in Adult ADHD Neurodevelopment) (OCEAN)

Attention Deficit Hyperactivity Disorder (ADHD)

United Kingdom
Abbott Medical Devices

Not yet recruiting

External Sensing and Neuromodulation to Assess Diabetic Pain Outcomes (XANADO) (XANADO)

Chronic Pain

United States
Ukrainian Institute on Public Health Policy
Yale University; Alliance for Public Health

Active, not recruiting

Integrating Treatment for Mental Disorders in Methadone Clinics in Ukraine (MEDIUM)

Depression | Opioid Use Disorder

Ukraine
University of Jaen
Histocell, S.L.; Andalusian Health Service: District Poniente Almería.; Andalusian... and other collaborators

Completed

Evaluation of the Efficacy of an Antioxidant Dressing in Chronic Wound Healing (REOX)

Hard-to-heal Wounds

Spain
Biocad

Terminated

Clinical Study of the Safety and Immunogenicity of a Recombinant Viral Vector AAV5 (Adeno-Associated Virus Type 5 )-RBD (Receptor Binding Domain)-S Vaccine for the Prevention of Coronavirus Infection (COVID-19) (COVER)

COVID-19 | Coronavirus Infection

Russian Federation
University of Pennsylvania
National Institute of Mental Health (NIMH)

Completed

Effect of HIV/STD Risk Reduction Program on South African Adolescents

HIV Infections | Sexually Transmitted Disease
Medical University Innsbruck

Unknown

Personality Pathology and Cerebral Processing in Eating Disorders (EAT_FMRI)

Eating Disorders

Austria
Brooke Army Medical Center

Completed

Skin Refrigerant to Reduce the Pain Associated With IV Insertion

Pain

United States
Organon and Co

Completed

Efficacy and Safety Study of Ezetimibe (SCH 58235, MK-0653) in Addition to Atorvastatin in Participants With Coronary Heart Disease or Multiple Cardiovascular Risk Factors (P00693/MK-0653-030)

Hypercholesterolemia

3

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