Search clinical trials for: Letermovir intravenous

Total 6440 results

Merck Sharp & Dohme LLC

Completed

Letermovir Treatment in Pediatric Participants Following Allogeneic Haematopoietic Stem Cell Transplantation (HSCT) (MK-8228-030)

Cytomegalovirus (CMV) Infection

United States, Australia, Colombia, France, Germany, Israel, Japan, Mexico, Poland, Spain, Turkey
The First Affiliated Hospital of Soochow University

Recruiting

Letermovir for the Prevention of CMV Infection in HSCT Recipients Based on the Outcome of mNGS

Hematopoietic Stem Cell Transplantation | CMV Infection

China
National Institute of Allergy and Infectious Diseases...
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Anti-inflammatory Effects of Letermovir (Prevymis) in Adults With Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive Antiretroviral Therapy, Plus Its Effect on Chronic Inflammation, HIV Persistence and Other Clinical Outcomes. (ELICIT)

HIV Infections | Cytomegalovirus | CMV

United States
Merck Sharp & Dohme LLC

Completed

MK-8228 (Letermovir) in the Prevention of Human Cytomegalovirus (CMV) Infection and Disease in Adult Japanese Kidney Transplant Recipients (MK-8228-042)

Cytomegalovirus Infection | Cytomegalovirus Disease

Japan
University Medical Centre Ljubljana

Recruiting

Cytomegalovirus Prophylaxis With Letermovir in Heart Transplant Recipients (CYPHER-TXPilot)

CMV Viremia

Slovenia
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Letermovir-based Dual Therapy for Treatment of Cytomegalovirus Infections (LUCY-1)

Cytomegalovirus Infection

France
Memorial Sloan Kettering Cancer Center
Merck Sharp & Dohme LLC

Recruiting

A Study of the Drug Letermovir (LTV) as Prevention for Recurrent of Cytomegalovirus (CMV) Infection

CMV | CMV Infection | Hematopoietic Cell Transplant

United States
Maimónides Biomedical Research Institute of Córdoba
MERCK SHARP & DOHME DE ESPAÑA S.A.

Not yet recruiting

Efficacy of Letermovir in Preventing Cytomegalovirus (CMV) Infection in Lung Transplant Recipients vs. Valganciclovir. (LETERCOR)

Infections, Cytomegalovirus

Spain
University of Pennsylvania
Merck Sharp & Dohme LLC

Recruiting

Open Label Trial of Oral Letermovir for CMV Prophylaxis in Thoracic Transplant Recipients

Cytomegalovirus Infections | Transplant-Related Disorder

United States
Virginia Commonwealth University
Merck Sharp & Dohme LLC

Recruiting

De-novo Initiation of Letermovir vs Valganciclovir for Cytomegalovirus Prophylaxis in AA Kidney Trans Recip

CMV | Kidney Transplant; Complications

United States
Hospital do Rim e Hipertensão

Not yet recruiting

Evaluation of the Prophylactic Use of Letermovir in Kidney Transplant Recipients at Risk of Cytomegalovirus Infection

CMV Infection
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

Secondary Prophylaxis of CMV Infection Using Letermovir After HID-HSCT

To Evaluate the Efficacy and Safety of Secondary Prophylaxis of CMV Reactivation
Assistance Publique - Hôpitaux de Paris

Completed

Prenatal Treatment of Congenital Cytomegalovirus Infection With Letermovir Randomized Against Valaciclovir - STEP 1 (CYMEVAL3-STEP1) (CYMEVAL3-STEP1)

Pregnant Women Undergoing TOP | TOP - Failed Attempted Termination of Pregnancy

France
Peking University People's Hospital

Enrolling by invitation

Immune Reconstitution to CMV After HSCT: Impact of Clinical Factors and Therapy Strategies

Hematopoietic Stem Cell Transplantation | CMV Infection

China
Tufts Medical Center
Merck Sharp & Dohme LLC

Active, not recruiting

Letermovir Use in Heart Transplant Recipients

Neutropenia | Cytomegalovirus Infections | Cytomegalovirus Disease | Heart Transplant Infection | Antiviral Toxicity

United States
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

A Safety Assessment of Oral Letermovir in Infants With Symptomatic Congenital Cytomegalovirus

Congenital Cytomegalovirus Infection
Tufts Medical Center

Recruiting

Letermovir for Secondary Prophylaxis in Solid Organ Transplant Recipients

Neutropenia | Cytomegalovirus Infections | Infection in Solid Organ Transplant Recipients | Antiviral Toxicity

United States
Jean-Pierre Routy

Recruiting

Letermovir in ART-treated HIV-infected Persons (Letermovir)

People Living With HIV

Canada
The First Affiliated Hospital of Soochow University

Recruiting

Letermovir Prophylaxis for CMV Infection in Haplo-HSCT Recipients: Single-center Data in China

Hematopoietic Stem Cell Transplantation | CMV Infection

China
University of Wisconsin, Madison
Merck Sharp & Dohme LLC

Not yet recruiting

Letermovir (Prevymis) for CMV in Kidney and Pancreas Transplant Recipients

Kidney Transplant Infection | Cytomegalovirus Infections | Pancreas Transplant

United States
Yuzuncu Yıl University

Unknown

Powder Topical Rifampicin on Reducing Infections After Neural Tube Defect Surgery in Infants

Postoperative Infection Rates

Turkey
Cao Weijie

Recruiting

Observational Clinical Study of Letermovir for Preventing CMV Infection After Allo-HSCT

Letemovir for the Prevention of CMV Infection After Allo-HSCT

China
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

Letermovir for Primary Prophylaxis of Cytomegalovirus Infection After R+HID-HSCT

The Incidence of Peripheral Blood CMV Activation and Confirmed Clinically Significant CMV Infection Within 24 Weeks After Transplantation
Amy C. Sherman, MD
Merck Sharp & Dohme LLC

Completed

Letermovir Treatment for Refractory or Resistant Cytomegalovirus Infection

Cytomegalovirus Infections

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Prenatal Treatment of Congenital Cytomegalovirus Infection With Letermovir Versus Valaciclovir (CYMEVAL3-step2)

Pregnant Women | CMV Infected Fetuses

France
Merck Sharp & Dohme LLC

Completed

A Study of Letermovir (MK-8228) to Evaluate Efficacy and Safety for Prevention of CMV Infection in Chinese Hematopoietic Stem Cell Transplant Recipients (MK-8228-045)

Cytomegalovirus Infection

China
Royan Institute

Completed

Autologous Bone Marrow Derived Mesenchymal Stromal Cells (BM-MSCs) in Patients With Chronic Kidney Disease (CKD)

Chronic Kidney Disease

Iran, Islamic Republic of
Mongi Slim Hospital

Completed

Prevention of Bleeding in Total Joint Replacement: Combined Route Administration of Tranexamic Acid

Arthroplasty, Replacement, Knee | Blood Transfusion | Arthroplasty, Replacement, Hip | Tranexamic Acid

Tunisia
Rabin Medical Center

Not yet recruiting

Letermovir Prophylaxis for Cytomegalovirus (CMV) in Patients With Graft-versus-host Disease

CMV | Graft-versus-host-disease
AiCuris Anti-infective Cures AG
Quintiles, Inc.

Completed

Safety and Efficacy Study of a New Antiviral Drug to Prevent Cytomegalovirus Reactivation in Bone Marrow Transplanted Patients

HCMV Reactivation or HCMV End-Organ Disease

United States, Germany
University of Minnesota

Completed

Enhanced Nutrition for Preterm Infants

Preterm Birth

United States
Galapagos NV
MorphoSys AG

Completed

First in Human of Single and Multiple Doses of MOR106

Healthy | Dermatitis, Atopic

Belgium, Hungary, Moldova, Republic of, Romania
Fernanda P Silveira, MD, MS
Merck Sharp & Dohme LLC

Recruiting

Letermovir for CMV Prevention After Lung Transplantation

CMV | Lung Transplant

United States
Baxalta now part of Shire

Completed

Study to Determine the Dose of Recombinant Human Hyaluronidase Needed to Infuse a Full Dose of IGIV Subcutaneously

Primary Immunodeficiency Diseases (PID)

United States
Merck Sharp & Dohme LLC

Completed

Extension of Letermovir (LET) From Day 100 to Day 200 Post-transplant for the Prevention of Cytomegalovirus (CMV) Infection in Hematopoietic Stem Cell Transplant (HSCT) Participants (MK-8228-040)

Cytomegalovirus Infection

United States, France, Germany, Italy, Japan, United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP6294 Administered Intravenously or Subcutaneously in Healthy Young Male and Female Subjects

Healthy Subjects | Pharmacokinetics of ASP6294

United Kingdom
MicuRx
Worldwide Clinical Trials

Completed

Single Dose Escalation and Multiple Dose Escalation Trial of an Intravenous Formulation of MRX-4

Safety
Asklepion Pharmaceuticals, LLC

Completed

Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised Protocol

Atrial Septal Defect | Atrioventricular Septal Defect | Ventricular Septal Defect

United States
Eli Lilly and Company

Completed

A Study of LY3016859 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Chaitanya Hospital, Pune

Unknown

Study Safety and Efficacy of BMMNC for the Patient With Duchenne Muscular Dystrophy (BMMNC)

Muscular Dystrophy | Duchenne Muscular Dystrophy

India
Merck Sharp & Dohme LLC

Completed

Letermovir (MK-8228) Versus Placebo in the Prevention of Clinically-Significant Cytomegalovirus (CMV) Infection in Adult, CMV-Seropositive Allogeneic Hematopoietic Stem Cell Transplant Recipients (MK-8228-001)

Prevention of CMV Infection or Disease
GlaxoSmithKline

Completed

SB-681323 IV for Subjects at Risk of Acute Lung Injury or ARDS

Lung Injury, Acute

United States
Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Completed

A Multicenter Phase I/II Clinical Trial to Evaluate Safety of Mesenchymal Stem Cell in Patients With Amyotrophic Sclerosis Lateral

Amyotrophic Lateral Sclerosis

Spain
UCB Celltech
Parexel

Completed

A First-In-Human Study With a Single Dose UCB7665 in Healthy Volunteers

Healthy

United Kingdom
Novartis Pharmaceuticals

Completed

MCS110 in Patients With Pigmented Villonodular Synovitis (PVNS)

Pigmented Villonodular Synovitis | PVNS | Giant Cell Tumor of the Tendon Sheath | GCCTS | Tenosynovial Giant Cell Tumor Localized or Diffused Type | GCTS

United States, Switzerland
University of Foggia

Unknown

Evaluation of the Active Warming Effects on Maternal and Neonatal Outcome During Cesarean Delivery

Hypothermia; Anesthesia

Italy
Centre Hospitalier Departemental Vendee
Institut National de la Santé Et de la Recherche Médicale, France; Ministry... and other collaborators

Terminated

Impact of Early Enteral vs. Parenteral Nutrition on Risk of Gastric-Content Aspiration in Patients Requiring Mechanical Ventilation and Catecholamines

Shock | Acute Respiratory Failure

France
Centre Hospitalier Departemental Vendee
Institut National de la Santé Et de la Recherche Médicale, France; Ministry... and other collaborators

Terminated

Impact of Early Enteral vs. Parenteral Nutrition on Preservation of Gut Mucosa Integrity in Patients Requiring Mechanical Ventilation and Catecholamine

Shock | Acute Respiratory Failure

France
Serum Institute of India Pvt. Ltd.
PPD

Completed

Safety Study of Dengushield in Healthy Adults

Dengue | Phase 1

Australia
Rebecca Price
Gate Neurosciences, Inc

Not yet recruiting

Apimostinel + Automated Neurocognitive Training for Depression

Depression

United States

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