Search clinical trials for: Letrozole (aromatase inhibitor)

Total 64153 results

Xinhua Hospital, Shanghai Jiao Tong University...

Recruiting

Letrozole Combined With Anlotinib Hydrochloride in the Treatment of Platinum-resistant Recurrent Ovarian Cancer

Platinum-resistant Recurrent Ovarian Cancer

China
Zagazig University

Completed

Evaluation of Different Doses of Letrozole in Ectopic Pregnancy (letrezole)

Ectopic Pregnancy

Egypt
National University Hospital, Singapore
Eisai Co., Ltd.

Unknown

Neoadjuvant Lenvatinib Combined With Letrozole in Hormone Receptor Positive Breast Cancer

Breast Cancer

Singapore
NHS Tayside

Completed

Radiological and Biological Tumoural and Peri-tumoural Factors in Neoadjuvant Endocrine-treated Breast Cancers (BARONET)

Breast Cancer

United Kingdom
University of California, San Francisco
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Not yet recruiting

Prescription of Letrozole for Uterine Myoma (PLUM)

Leiomyoma | Fibroid | Fibroid Uterus | Leiomyoma, Uterine

United States
Shuangyue Liu

Not yet recruiting

Study of Dalpiciclib Combined With Letrozole in the Maintenance Treatment of HR Positive and HER2 Negative Metastatic Breast Cancer After First-line Chemotherapy

Breast Cancer

China
Hunan Cancer Hospital
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

Pyrotinib in Combination With Letrozole in Patients With HER2-Positive, ER-Positive Metastatic Breast Cancer

Metastatic Breast Cancer

China
Rigshospitalet, Denmark

Terminated

A Randomized, Double-blinded, Clinical, Placebo-controlled Trial on the Effects of Therapy With Letrozole and hUman Choriongonadotropin in Male Hypogonadism Induced by Illicit Use of Anabolic Androgenic Steroids- The LUCAS Trial

Hypogonadotropic Hypogonadism | Hypogonadism | Hypogonadism, Male

Denmark
Peking University Third Hospital

Completed

Intrauterine Insemination With Letrozole Versus in Natural Cycle

Infertility | Intrauterine Insemination

China
Bristol-Myers Squibb
Mayo Clinic

Terminated

Study of BMS-754807 Combined With Letrozole or BMS-754807 Alone in Patients With Hormone Receptor-Positive Breast Cancer and Resistance to Non-Steroidal Aromatase Inhibitors

Breast Cancer

United States
NCIC Clinical Trials Group

Completed

Letrozole in Treating Women With Recurrent or Metastatic Endometrial Cancer

Endometrial Cancer
Pfizer

Completed

European Treatment Patterns and Outcomes Associated With First-Line CDK4/6 Inhibition and Hormonal Therapies (EUCHARIS)

Metastatic Breast Cancer

Spain, Belgium, Sweden, United Kingdom, Austria, Germany, Switzerland
Henan Cancer Hospital

Not yet recruiting

Darsilide Combined With AI, Trastuzumab and Patuzumab in the Neoadjuvant Treatment of HR+/HER2+ Breast Cancer

Breast Cancer | HER2-positive Breast Cancer

China
Menoufia University

Recruiting

Letrozole /GnRH Antagonist Protocol in Women Over 40 Years Undergoing ICSI Cycle

Ovarian Stimulation

Egypt
Assiut University

Not yet recruiting

Letrozole Plus Metronomic Capecitabine as First-line Treatment for Patients With Recurrent or Metastatic Breast Cancer

Metastasis Breast
Borstkanker Onderzoek Groep
Novartis; Philips Healthcare

Active, not recruiting

Tailoring NEOadjuvant Therapy in Hormone Receptor Positive, HER2 Negative, Luminal Breast Cancer. (NEOLBC)

Breast Neoplasms

Netherlands
NCIC Clinical Trials Group
National Cancer Institute (NCI); European Organisation for Research and Treatment... and other collaborators

Completed

Letrozole After Tamoxifen in Treating Women With Breast Cancer

Breast Cancer

United Kingdom, Canada
Cairo University

Unknown

Effectiveness of Pretreatment Letrozole Versus Misoprostol Alone in Missed Abortion

Medical; Abortion, Fetus
Pfizer

Completed

A Study Of Oral Palbociclib (PD-0332991), A CDK4/6 Inhibitor, As Single Agent In Japanese Patients With Advanced Solid Tumors Or In Combination With Letrozole For The First-Line Treatment Of Postmenopausal Japanese Patients With ER (+) HER2 (-) Advanced Breast Cancer

Neoplasms | Breast Neoplasms

Japan
The University of Hong Kong
Peking University Third Hospital

Completed

Letrozole in Stimulated IVF Cycles

Subfertility

China
Novartis

Completed

Letrozole in Treating Postmenopausal Women With Metastatic Breast Cancer

Breast Cancer

United States
Wyeth is now a wholly owned subsidiary of Pfizer
Pfizer

Completed

Study Evaluating Temsirolimus (CCI-779) In Breast Neoplasms

Breast Neoplasms
Jagiellonian University

Completed

Letrozole add-on in the Treatment of Cesarean Scar Pregnancy

Cesarean Scar Pregnancy

Poland
Shereen Rady Abou El-fetouh

Unknown

Letrozole Pretreatment With Misoprostol Induction of Abortion in First Trimester Missed Abortion

Missed Abortion
Novartis Pharmaceuticals

Terminated

A Companion Sample Collection Protocol to Support the Discovery of Breast Cancer Aberrations With Treatment of CDK4/6 Therapy/LEE011/Ribociclib

Breast Cancer

United States
Roxane Laboratories

Completed

Bioequivalency Study of Letrozole 2.5 mg Tablets Under Fed Conditions

Breast Cancer

United States
Washington University School of Medicine
National Cancer Institute (NCI)

Completed

Neoadjuvant Letrozole in Treating Postmenopausal Women With Estrogen-Receptor Positive and/or Progesterone-Receptor Positive Stage II, Stage IIIA, or Stage IIIB Breast Cancer

Breast Cancer

United States
Shengjing Hospital

Active, not recruiting

Pyrotinib Maleate, CDK4/6 Inhibitor and Letrozole in Combination for Stage II-III TPBC: a Phase II Trial

Breast Cancer

China
Novartis Pharmaceuticals

Completed

Rheumatological Evaluation of Anastrozole and Letrozole as Adjuvant Treatment in Post-menopausal Women With Breast Cancer (REAL)

Breast Cancer

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Letrozole in Treating Postmenopausal Women With Stage I, II or III Breast Cancer That Can Be Removed by Surgery

Breast Cancer

United States
Pfizer

Completed

Study to Evaluate Overall Survival in Japanese Patients With HR+/HER2- Advanced Breast Cancer Treated With Palbociclib Plus Letrozole

Breast Cancer

Japan
Organisation for Oncology and Translational Research

Unknown

Letrozole and CDK 4/6 Inhibitor for ER Positive, HER2 Negative Breast Cancer in Postmenopausal Women

ER Positive, HER2 Negative Breast Cancer

China
Imperial College London
AstraZeneca; Cancer Research UK

Completed

AZD4547 & Anastrozole or Letrozole (NSAIs) in ER+ Breast Cancer Patients Who Have Progressed on NSAIs (RADICAL) (RADICAL)

Breast Cancer

United Kingdom
Yunyang Medical College

Unknown

Letrozole Combined With Gonadotropins (Gn) for Ovarian Stimulation Undergoing in Vitro Fertilization/Intracytoplasmic Sperm Injection (IVF/ICSI) in Patients With Polycystic Ovary Syndrome (PCOS)

Polycystic Ovarian Syndrome

China
The Affiliated Hospital of Qingdao University
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Neoadjuvant Dalpiciclib Plus Letrozole for HR+/HER2- Breast Cancer

Breast Cancer
Centre Leon Berard

Recruiting

Evaluation of Clinical Impact of Interruption VS Maintenance of AI in Patients With Locally Advanced/ Metastatic Low Grade Endometrial Stromal Sarcoma (LGESS) (BFR-ESS)

Low Grade Endometrial Stromal Sarcoma

France
Canadian Cancer Trials Group
Alliance for Clinical Trials in Oncology; Eastern Cooperative Oncology Group; North Central Cancer Treatment Group and other collaborators

Completed

Letrozole in Breast Cancer Who Have Received 5 Years of Aromatase Inhibitor Therapy

Breast Cancer

Canada, United Kingdom
Cairo University

Unknown

Letrozole and Metronomic Capecitabine in ER-positive HER2 Negative Advanced Breast Cancer (B-001 Study) (B-001)

Breast Cancer | Metastatic Breast Cancer | Estrogen Receptor-positive Breast Cancer

Egypt
Pfizer

Terminated

Pre-Operative Study of PF-4691502 With Letrozole Compared To Letrozole Alone In Patients With Early Breast Cancer

Early Breast Cancer (Phase 2) | Advanced Breast Cancer (Phase 1b)

Spain, Sweden, Italy, Belgium
Novartis Pharmaceuticals
Roche - Prof. Dr. Jens Huober et al.

Terminated

Study of the Efficacy and Safety of Letrozole Combined With Trastuzumab in Patients With Metastatic Breast Cancer (eLEcTRA)

Metastatic Breast Cancer

Germany
Finn, Olivera, PhD
Breast Cancer Research Foundation; A Glimmer of Hope Foundation

Recruiting

Prototype DAA/TAA Vaccine Targeting MUC1 for Immune Interception and Prevention in Ductal Carcinoma In Situ

Ductal Carcinoma in Situ

United States
Pfizer

Completed

PF-06804103 Dose Escalation in HER2 Positive and Negative (Negative Only in Part 2) Solid Tumors

Breast Neoplasms

Spain, Korea, Republic of, United States, Australia, Italy, Russian Federation
Ahon Pharmaceutical Co., Ltd.

Recruiting

This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c Versus Placebo in Combination With Letrozole or Anastrozole ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.

Advanced Breast Cancer | Female Breast Cancer

China
Nik Hazlina

Completed

The Effects of Letrozole And Clomiphene Citrate For Induction of Ovulation In Polycystic Ovarian Syndrome(PCOS)

Polycystic Ovarian Syndrome
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Terminated

Safety, Tolerability, and Efficacy Study in Subjects With Advanced or Metastatic Breast Cancer

Breast Cancer

United States
MedSIR
Pfizer

Completed

Neoadjuvant Letrozole and Palbociclib in Patients With Stage II-IIIB Breast Cancer, HR+, HER2 - (DxCARTES)

Breast Cancer

Spain, Portugal
Fujian Medical University Union Hospital

Not yet recruiting

Dalpiciclib Plus Letrozole and Capecitabine

Advanced Breast Cancer
Guangdong Provincial People's Hospital

Completed

Neoadjuvant Endocrine Therapy in Breast Cancer

Highly Endocrine Responsive Operable Breast Cancer

China
Sinai Hospital of Baltimore

Unknown

Single Arm Trial With Combination of Everolimus and Letrozole in Treatment of Platinum Resistant Relapse or Refractory or Persistent Ovarian Cancer/Endometrial Cancer

Ovarian Cancer | Endometrial Cancer

United States
Borstkanker Onderzoek Groep

Active, not recruiting

Endocrine Therapy Plus CDK4/6 in First or Second Line for Hormone (SONIA) Receptor Positive Advanced Breast Cancer

Breast Neoplasm Female

Netherlands

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