Search clinical trials for: Lidocaine and Bupivacaine solution

Total 22780 results

Merz Pharmaceuticals GmbH

Completed

Dose-response Study of Efficacy and Safety of Botulinum Toxin Type A to Treat Spasticity of the Leg(s) in Cerebral Palsy

Lower Limb Spasticity Due to Cerebral Palsy

Poland, Austria, Czechia, Estonia, France, Germany, Israel, Korea, Republic of, Romania, Russian Federation, Slovakia, Spain, Turkey, Ukraine
University of Barcelona

Completed

Is the Direct Inferior Alveolar Nerve Block Required for Third Lower Molar Extraction?

Tooth Extraction | Dental Anesthesia

Spain
University of Eastern Finland

Unknown

Touchscreen-based Cognitive Tests in Healthy Volunteers

Schizophrenia | Cognitive Symptom

Finland
University Hospital, Tours

Completed

Evaluation of the Effectiveness of the Nebulization Bronchodilators Under High Nasal Flow Humidified (AirvoNEB)

Chronic Obstructive Pulmonary Disease

France
University of New Mexico
Society of Family Planning

Completed

Nitrous Oxide for Pain Management of Intrauterine Device (IUD) Insertion (NIUD)

Contraception

United States
Eye Therapies, LLC
ORA, Inc.

Completed

A Single-Center, Randomized, Double-Masked, Placebo and Active Controlled, Dose-Ranging Evaluation of the Duration of Action of Brimonidine Tartrate Ophthalmic Solution in the Control of Ocular Redness Induced by Conjunctival Allergen Challenge (CAC)

Allergic Conjunctivitis

United States
Pearl Therapeutics, Inc.

Completed

24-hour Lung Function in Subjects With Moderate to Very Severe COPD After Treatment With PT003, Open-Label Spiriva® Respimat® as an Active Control, and Placebo

COPD
Janssen Research & Development, LLC

Completed

Cardiovascular Outcomes in Participants With Type 2 Diabetes Mellitus (T2DM)

Diabetes Mellitus, Type 2

United States
Chiesi Farmaceutici S.p.A.

Recruiting

A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD (TRITON)

COPD | COPD Exacerbation

United States, Bulgaria, Hungary, Poland, Argentina, Czechia, Mexico, Canada, Puerto Rico, Romania
Montefiore Medical Center

Recruiting

Pilocarpine Use After Kahook Goniotomy (PAACK)

Glaucoma

United States
University of Patras

Completed

Dexmedetomidine-ketamine Combination Versus Fentanyl-midazolam During Bronchoscopy

Lung Diseases | Anesthesia | Diagnosis

Greece
Boehringer Ingelheim

Completed

A Study in Healthy People to Test Whether BI 730357 Influences the Amount of Caffeine, Warfarin, Omeprazole, and Midazolam in the Blood

Healthy

Germany
Novartis Pharmaceuticals

Completed

Open-label, Phase II, Study of Everolimus Plus Letrozole in Postmenopausal Women With ER+, HER2- Metastatic or Locally Advanced Breast Cancer (BOLERO-4)

Hormone Receptor Positive Breast Cancer

United States, Argentina, Thailand, Japan, France, Korea, Republic of, Spain, Turkey, Hungary, United Kingdom, Portugal, Brazil, Netherlands
Sanofi

Completed

A Study to Demonstrate Bioequivalence Between Insulin Glulisine U300 and Insulin Glulisine U100 After a Single Subcutaneous Dose Using the Euglycemic Clamp Technique, in Patients With Type 1 Diabetes Mellitus

Type1 Diabetes Mellitus

Germany
Sanofi

Completed

Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FRC Extension Period (LixiLan-G)

Type 2 Diabetes Mellitus

Estonia, Italy, Israel, United States, Canada, Germany, Romania, Slovakia, Spain
Aalborg University

Withdrawn

Characterization of the Toll-like Receptor 7-agonist Imiquimod 3.75% as a New Surrogate Model of Itch

Itch

Denmark
Baxalta now part of Shire
Kamada, Ltd.

Terminated

A Phase 2/3 Study of GLASSIA for the Treatment of Acute GvHD

Graft Versus Host Disease

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Evaluation of Dupilumab in Patients With Severe Steroid Dependent Asthma (VENTURE)

Asthma

Belgium, Israel, United States, Mexico, Argentina, Brazil, Canada, Chile, Colombia, Hungary, Italy, Netherlands, Poland, Romania, Russian Federation, Spain, Ukraine
Avanir Pharmaceuticals

Completed

Study to Assess the Bioavailability, Pharmacokinetics, Safety, and Tolerability of AVP-923 in Healthy Adult Participants

Healthy Adult Male and Female Volunteers

United States
Hoffmann-La Roche

Completed

A Two-part, Single-dose, Randomized Study to Evaluate the Safety of Supra-therapeutic Doses of RO7033877 and to Investigate the Effect of RO7033877 on the QTc Interval

Healthy Volunteer

United States
Universidade Federal de Santa Maria
Hospital de Clinicas de Porto Alegre; Santa Casa de Misericórdia de Belo Horizonte

Completed

Methadone and Ketamine for Neuropathic Pain Treatment

Neuropathic Pain

Brazil
University of Parma

Terminated

Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery

Pain, Postoperative | Anesthesia Recovery Period

Italy
Universidad de Guanajuato
Antisepsia Central

Completed

Residual Effect of Chlorhexidine-alcohol Compared to Triclosan-alcohol

Infectious Diseases

Mexico
Milton S. Hershey Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Childhood Asthma Research and Education (CARE) Network Trial - Best Add-On Therapy Giving Effective Response (BADGER) (BADGER)

Asthma

United States
Oregon Health and Science University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Active, not recruiting

Regulation of Cortisol Metabolism and Fat Patterning

Obesity | Menopausal Syndrome

United States
Universidade Federal do Para

Not yet recruiting

Pregabalin Gel in Reducing Post-operative Tooth Sensitivity Surgery Caused by Bleaching With 35% Hydrogen Peroxide

Tooth Bleaching | Sensitivity, Tooth

Brazil
Qianfoshan Hospital

Recruiting

Efficacy and Safety Study of Medical Thoracoscope Cryotherapy Combined Standard First-line Treatment of Advanced Non-small Cell Lung Cancer and Malignant Pleural Effusion

Non Small Cell Lung Cancer

China
Sandoz

Not yet recruiting

Efficacy and Safety of the Combination of Acetylcysteine, Paracetamol and Phenylephrine for the Treatment of Common Cold

Common Cold
Ankara University

Completed

Different Noradrenaline Protocols in Post Spinal Hypotension in CS

Hypotension | Cesarean Section | Anesthesia, Spinal

Turkey
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Safety and Effectiveness of Emtricitabine, Efavirenz, and Didanosine in HIV Infected Children Who Have Taken Few or No Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
Sanofi

Completed

Efficacy and Safety of Lixisenatide Versus Insulin Glulisine on Top of Insulin Glargine With or Without Metformin in Type 2 Diabetic Patients (GetGoal-Duo-2)

Type 2 Diabetes

United States, Canada, Chile, Czech Republic, Estonia, France, Germany, Hungary, Italy, Latvia, Lithuania, Mexico, Poland, Romania, Russian Federation, Spain, Ukraine, United Kingdom
James J. Peters Veterans Affairs Medical Center

Unknown

GERD and Anti-Reflux Therapy Between Able-bodied and SCI Individuals

Gastro Esophageal Reflux Disorder

United States
NEMA Research, Inc.

Recruiting

Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following Bunionectomy

Pain, Postoperative

United States
FX Solutions

Recruiting

Post Market Clinical Follow-up Study for Arthroplasty Shoulder System of FX Solutions at the Long Term

Shoulder Fractures | Shoulder Disease | Shoulder Arthroplasty for Revision of Previous Treatment

Monaco, France
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A 24-Week Treatment Study to Compare Standard of Care Versus the eMDPI DS in Participants 13 Years or Older With Asthma (CONNECT2)

Asthma

United States
MEDA Pharma GmbH & Co. KG

Completed

DYmista NAsal Spray in CHInese Patients (DYNAS-CHI)

Allergic Rhinitis

China
Assistance Publique - Hôpitaux de Paris

Unknown

Best Promising Drug Association With Azacitidine in Higher Risk Myelodysplastic Syndromes (AZA-PLUS)

MDS

France
Sanofi

Completed

Treatment Extension Study for Patients Who Have Previously Participated and Have Benefited From Iniparib in a Clinical Trial

Solid Tumors

Belgium, Italy, United States, Spain
Rutgers, The State University of New Jersey
Bausch & Lomb Incorporated

Completed

Safety and Efficacy Study of Besivance™ for Treatment of Congenital Nasolacrimal Duct Obstruction in Children

Congenital Nasolacrimal Duct Obstruction

United States
Sanofi

Completed

Comparison of Two Treatment Regimens in Patients With Type 2 Diabetes After Short-term Intensive Insulin Therapy (SWITCH)

Type 2 Diabetes Mellitus

China
Baxalta now part of Shire

Completed

Tolerability and Safety of Immune Globulin Subcutaneous Solution (IGSC) and rHuPH20 in PID

Primary Immunodeficiency Diseases (PID)

United States
Sanofi
Regeneron Pharmaceuticals

Completed

A Study Assessing the Safety and Efficacy of Sarilumab Added to Non-MTX DMARDs or as Monotherapy in Japanese Patients With Active Rheumatoid Arthritis (SARIL-RA-HARUKA)

Rheumatoid Arthritis

Japan
Sanofi
Regeneron Pharmaceuticals

Terminated

Effect of SAR153191 (REGN88) With Methotrexate in Patients With Active Rheumatoid Arthritis Who Failed TNF-α Blockers

Rheumatoid Arthritis

United States, Italy, Mexico, Colombia, Czechia, Spain
Tonix Pharmaceuticals, Inc.

Completed

Comparative Bioavailability of Sublingual TNX-102, Oral and Intravenous Cyclobenzaprine in Healthy Adults

Healthy Adults

Canada
GlaxoSmithKline
Bill and Melinda Gates Foundation; Wellcome Trust; Biomedical Advanced Research... and other collaborators

Recruiting

A Study to Evaluate Safety, Reactogenicity, and Immune Response of GVGH iNTS-TCV Vaccine Against Invasive Nontyphoidal Salmonella and Typhoid Fever

Salmonella Infections

Belgium, Malawi
Dar El Oyoun Hospital

Unknown

Subconjunctival Atropine and Intracameral Epinephrine for Pupil Dilation in Phacoemulsification

Cataract | Adverse Drug Event | Mydriasis

Egypt
Ain Shams University

Not yet recruiting

Comparing the Effect of Different Intracanal Dressing on Failed Root Canal Treated Cases on Periapical Healing

Periapical Disease

Egypt
Sanofi

Recruiting

A Prospective Study to Investigate Safety and Tolerability of Shorter Infusion of Fabrazyme (SHORTEN)

Fabry's Disease

United States
University Hospital, Geneva

Completed

Swiss PACK-CXL Multicenter Trial for the Treatment of Infectious Keratitis

Keratitis; Infectious Disease (Manifestation)

Switzerland
Hal Chapman
Massachusetts General Hospital; University of Michigan; University of Washington and other collaborators

Recruiting

Study of Oral Epigallocatechin-3-gallate (EGCG) in IPF Patients

Idiopathic Pulmonary Fibrosis

United States

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