Search clinical trials for: Lipid Regulating Drugs

Total 257536 results

AIDS Malignancy Consortium
National Cancer Institute (NCI); The Emmes Company, LLC

Completed

Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed, HIV-Associated Burkitt's Lymphoma

Lymphoma

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Iodine I 131 Tositumomab, Etoposide and Cyclophosphamide Followed by Autologous Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Sun Yat-sen University

Unknown

Modified MRCUKALLⅫ/ECOGE2993 Regimen for ALL

Leukaemia,Lymphoblastic

China
National Cancer Institute (NCI)

Completed

Stem Cell Transplantation in Patients With High-Risk and Recurrent Pediatric Sarcomas

Sarcoma

United States
Cairo University

Completed

Ovulation Induction in Women With Clomiphene Citrate Resistant PCOS

Polycystic Ovary Syndrome | Infertility

Egypt
Washington University School of Medicine
National Cancer Institute (NCI); National Institutes of Health (NIH); Atrium...

Completed

Comparative Effectiveness Multicenter Trial for Adhesion Characteristics of Ventral Hernia Repair Mesh

Ventral Hernia | Adhesions

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Completed

CINJALL: Treatment for Children With Acute Lymphocytic Leukemia

Acute Lymphocytic Leukemia

United States
National Cancer Institute (NCI)

Completed

Combination Chemo, Rituximab, and Bevacizumab in Older Patients With Stage II-IV Diffuse Large B-Cell Lymphoma

Stage III Adult Diffuse Large Cell Lymphoma | Stage IV Adult Diffuse Large Cell Lymphoma | Contiguous Stage II Adult Diffuse Large Cell Lymphoma | Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma

United States
Scottish Cancer Therapy Network

Completed

Standard Chemotherapy Compared With High-Dose Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Breast Cancer

Breast Cancer

United Kingdom, Ireland
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Followed By Donor Bone Marrow or Umbilical Cord Blood Transplant in Treating Children With Newly Diagnosed Juvenile Myelomonocytic Leukemia

Juvenile Myelomonocytic Leukemia

United States
St. Jude Children's Research Hospital
National Cancer Institute (NCI)

Completed

Treatment of Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplasia

Leukemia, Myelocytic, Acute

United States
University of Patras

Unknown

Epidural Volume Extension and Intrathecal Use of Local Anesthetics in Cesarean Sections

Stillborn Caesarean Section

Greece
Hadassah Medical Organization

Completed

Prediction of Drug Interactions With CYP2C9 Substrates

Healthy Volunteers

Israel
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of Belinostat and SGI-110 (Guadecitabine) or ASTX727 for the Treatment of Unresectable and Metastatic Conventional Chondrosarcoma

Metastatic Primary Central Chondrosarcoma | Unresectable Primary Central Chondrosarcoma | Locally Advanced Unresectable Primary Central Chondrosarcoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Polatuzumab Vedotin, Rituximab, Ifosfamide, Carboplatin, and Etoposide (PolaR-ICE) as Initial Salvage Therapy for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent Transformed B-Cell Non-Hodgkin Lymphoma | Refractory Transformed B-Cell Non-Hodgkin Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma | Refractory Primary Mediastinal (Thymic)... and other conditions

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Arsenic Trioxide and Ascorbic Acid Combined With Bortezomib, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma or Plasma Cell Leukemia

Multiple Myeloma and Plasma Cell Neoplasm

United States
University of Washington
Genentech, Inc.

Suspended

Polatuzumab Vedotin and Combination Chemotherapy for the Treatment of Untreated Aggressive Large B-cell Lymphoma

Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Aggressive Non-Hodgkin Lymphoma | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | High Grade B-Cell Lymphoma, Not Otherwise Specified | T-Cell/Histiocyte-Rich... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

Daratumumab, Bortezomib, Dexamethasone, Pegylated Liposomal Doxorubicin Hydrochloride, and Lenalidomide in Treating Participants With Plasma Cell Leukemia

Plasma Cell Leukemia

United States
Abramson Cancer Center at Penn Medicine

Not yet recruiting

FAPI-74 PET/CT in Adults With Fibrosis

Fibrosis (Morphologic Abnormality)

United States
Janssen Research & Development, LLC

Recruiting

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib (COCOON)

Carcinoma, Non-Small-Cell Lung

United States, Taiwan, Korea, Republic of, Malaysia, Turkey, France, Spain, China, Germany, Argentina, Brazil
World Health Organization
London School of Hygiene and Tropical Medicine; University of Ghana; Biomedical... and other collaborators

Recruiting

An Adolescent Health and Wellbeing Check-up Programme in Three African Cities (Y-Check) (Y-Check)

Health-Related Behavior | Adolescent Behavior | Adolescent Development | Health Care Seeking Behavior

Ghana, Tanzania, Zimbabwe
Inari Medical

Recruiting

DEFIANCE: RCT of ClotTriever System Versus Anticoagulation In Deep Vein Thrombosis (DEFIANCE)

Venous Thromboembolism | Deep Venous Thrombosis | Post-Thrombotic Syndrome

United States, Germany, Finland, Switzerland, United Kingdom
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

An Investigational Scan (68Ga-FAPI-46 PET/CT) for the Imaging of Cancer-Associated Fibroblasts in Patients With Localized Pancreatic Ductal Adenocarcinoma

Stage 0 Pancreatic Cancer AJCC v8 | Stage I Pancreatic Cancer AJCC v8 | Stage IIA Pancreatic Cancer AJCC v8 | Resectable Pancreatic Ductal Adenocarcinoma | Localized Pancreatic Adenocarcinoma

United States
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing the Addition of Ipatasertib to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) for Stage III or IV Epithelial Ovarian Cancer

Ovarian Endometrioid Adenocarcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Fallopian Tube Endometrioid Adenocarcinoma | Ovarian High Grade Serous Adenocarcinoma | Fallopian Tube High Grade Serous Adenocarcinoma | Primary Peritoneal Endometrioid Adenocarcinoma | Stage III Fallopian... and other conditions

United States
Susan Chang
GE Healthcare; Sigma-Aldrich; Phillips-Medisize

Recruiting

Serial MR Imaging and MR Spectroscopic Imaging for the Characterization of Lower Grade Glioma

Recurrent WHO Grade III Glioma | WHO Grade III Glioma | WHO Grade II Glioma | Recurrent World Health Organization (WHO) Grade II Glioma

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Collecting Information About Treatment Results for Patients With Cushing's Syndrome

Cushing Syndrome | Cushing's Disease | Cushing Disease

United States
St. Joseph's Hospital and Medical Center, Phoenix
The Cleveland Clinic; Thomas Jefferson University

Recruiting

Prophylactic Oral Antibiotics on Sinonasal Outcomes Following Endoscopic Transsphenoidal Surgery for Pituitary Lesions (POET)

Pituitary Adenoma | Antibiotics

United States
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF)

Cystic Fibrosis

United States, Spain, United Kingdom, New Zealand, Israel, Australia, Ireland, Germany, Sweden, Czechia, Portugal, Hungary
National Cancer Institute (NCI)

Active, not recruiting

Testing Nivolumab in Combination With Decitabine and Venetoclax in Patients With Newly Diagnosed TP53 Gene Mutated Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States
Ain Shams University

Completed

Efficacy of Vonoprazan in Eradication of Resistant Strain of Helicobacter Pylori

Helicobacter Pylori Infection

Egypt
Medecins Sans Frontieres, Netherlands
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Completed

Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s) (TB-PRACTECAL)

Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis

Belarus, South Africa, Uzbekistan
The Crofoot Research Center, Inc.
Janssen Scientific Affairs, LLC

Completed

Rapid Reinitiation of a Single Tablet Antiretroviral Therapy Using Symtuza® in HIV-1 Infected Treatment-Experienced Patients Off Therapy. (ReSTART) (ReSTART)

HIV-1-infection

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

DCE-MRI and MBI in Assessing Tumor Response to Chemotherapy in Patients With Triple Negative Breast Cancer

Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Ixabepilone in Treating Participants With Significant Residual Disease of HER2/Neu Negative Invasive Breast Cancer After Systemic Therapy

Invasive Breast Carcinoma | HER2/Neu Negative | Bilateral Breast Carcinoma

United States
Bristol-Myers Squibb

Active, not recruiting

A Study to Evaluate the Safety and Tolerability of BMS-986408 Alone and in Combination With Nivolumab or Nivolumab and Ipilimumab in Participants With Advanced Solid Tumors

Advanced Solid Tumors

Canada, United States, Spain, France, Switzerland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Nivolumab and Azacitidine With or Without Ipilimumab in Treating Patients With Refractory/Relapsed or Newly Diagnosed Acute Myeloid Leukemia

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Therapy-Related Acute Myeloid Leukemia | Acute Bilineal Leukemia and other conditions

United States
Daniel M. Spielman
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Detecting Lactate and Bicarbonate in Participants With Central Nervous System Tumors

Malignant Central Nervous System Neoplasm | Metastatic Malignant Neoplasm in the Central Nervous System

United States
Fundação Bahiana de Infectologia

Completed

Impact of a Dolutegravir-based Regimen on Early Mortality of AIDS Patients (IDEA)

Severely Immunocompromised HIV Patients

Brazil
National Cancer Center, Korea

Active, not recruiting

Effects of H. Pylori Eradication on the Gastric Preneoplastic Lesion and Neoplasm After ESD

Early Gastric Cancer | Helicobacter Pylori Infection | Endoscopic Resection

Korea, Republic of
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Active, not recruiting

Swallowing Outcomes and Circulating Tumor DNA in Patients With HPV Related Oropharyngeal Cancer Treated With Transoral Surgery and Reduced Intensity Adjuvant Therapy

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Oropharyngeal Human Papillomavirus-Positive Squamous...

United States
Ain Shams University

Completed

Potassium Copetitive Acid Blockers Efficacy in H.Pylori Eradication (P-CABs)

Helicobacter Pylori Eradication

Egypt
Northwell Health

Completed

Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy

Kidney Stones

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Gallium Ga 68-DOTATATE PET/CT in Predicting Tumor Growth in Patients With Meningiomas

Meningioma

United States
Portola Pharmaceuticals

Completed

A Healthy Volunteer PK/PD, Safety and Tolerability Study of Second Generation Andexanet Alfa

Bleeding

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb; National Cancer Institute (NCI); Candel Therapeutics, Inc.

Active, not recruiting

GMCI, Nivolumab, and Radiation Therapy in Treating Patients With Newly Diagnosed High-Grade Gliomas (GMCI)

Glioma, Malignant

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI); AIDS Associated Malignancies Clinical Trials...

Completed

Paclitaxel in Treating Patients With AIDS-Related Kaposi's Sarcoma

Sarcoma

United States
Novavax
Coalition for Epidemic Preparedness Innovations

Completed

Evaluation of the Safety and Immunogenicity of a SARS-CoV-2 rS Nanoparticle Vaccine With/Without Matrix-M Adjuvant

COVID-19

United States, Australia
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

First in Human Study of M4344 in Participants With Advanced Solid Tumors

Solid Tumor | Advanced Solid Tumor

Spain, United States, Netherlands, United Kingdom
Nektar Therapeutics

Terminated

Bempegaldesleukin and Pembrolizumab With or Without Chemotherapy in Locally Advanced or Metastatic Solid Tumors (PROPEL)

Non-Small Cell Lung Cancer

United States, Germany, Spain, Australia, France
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Fordham University

Completed

Trial of Individual Psychosocial Interventions for Cancer Patients

Advanced Solid Tumor Diseases

United States

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