Search clinical trials for: Lisdexamfetamine Dimesylate (LDX)

Total 2609 results

Shire

Completed

Co-Administration of LDX (SPD489) and Venlafaxine XR (EFFEXOR XR) in Healthy Volunteers

Healthy

United States
Shire

Completed

Safety, Tolerability, Pharmacokinetic, and Efficacy Study of SPD489 in Preschool Children With Attention-deficit/Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder (ADHD)

United States
Shire

Completed

Lisdexamfetamine Dimesylate 2-year Safety Study in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD)

Attention Deficit Hyperactivity Disorder (ADHD)

Germany, Italy, Poland, Spain, Romania, Belgium, Hungary, Netherlands, Sweden, United Kingdom
Shire

Completed

Forced-dose Titration of SPD489 in Adults With Binge Eating Disorder (BED)

Binge Eating Disorder

United States
Shire

Completed

Open Label Extension in Adults With Binge Eating Disorder (BED)

Binge Eating Disorder

Spain, United States, Germany
Aaron Keshen
Nova Scotia Health Authority

Terminated

Lisdexamfetamine for Adults With Bulimia Nervosa

Bulimia Nervosa

Canada
Shire

Completed

Evaluate the Maintenance of Efficacy of SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder

Binge Eating Disorder

United States, Spain, Germany, Canada, Sweden
Shire

Completed

Vyvanse Adolescent Open-Label Safety and Efficacy Extension Study

ADHD

United States
Shire

Completed

Double-blind, Placebo-controlled, Randomised Withdrawal, Extension, Safety and Efficacy Study of LDX in Children and Adolescents Aged 6-17

ADHD

Germany, Hungary, Italy, Poland, Sweden, United States, United Kingdom, Belgium, France
Shire

Completed

Assess the Safety and Pharmacokinetics of Ascending, Multiple Oral Doses of SPD489 in Adults With Schizophrenia

Schizophrenia

United States
Shire

Withdrawn

Safety and Efficacy of SPD489 in Adolescent Subjects Aged 13-17 Years With Attention-Deficit/Hyperactivity Disorder (ADHD)

ADHD

United States
University of Rhode Island
Lehigh University

Completed

Effects of LDX on Functioning of College Students With ADHD

Attention-deficit/Hyperactivity Disorder

United States
Shire

Completed

SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder

Binge Eating Disorder

United States, Germany
Shire

Completed

SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder

Binge Eating Disorder

United States, Spain, Germany, Sweden
Shire

Terminated

Long-term Safety of SPD489 When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults With Negative Symptoms of Schizophrenia

Schizophrenia

United States
Shire

Completed

SPD489 in Combination With an Antidepressant in the Treatment of Adults With Major Depressive Disorder

Major Depressive Disorder

United States, Chile, Australia, Argentina, United Kingdom
Shire

Completed

Randomized, Double-blind Safety and Efficacy Study of Lisdexamfetamine Dimesylate (LDX) in Children and Adolescents Aged 6-17

ADHD

Belgium, France, Germany, Hungary, Italy, Netherlands, Poland, Spain, Sweden, United Kingdom
Seattle Children's Hospital
Shire

Completed

Sequencing Treatments for Mothers With ADHD and Their At - Risk Children (TMF)

Attention Deficit Hyperactivity Disorder

United States
Shire

Completed

Efficacy and Safety of Lisdexamfetamine Dimesylate (LDX) in Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD)

Attention Deficit Hyperactivity Disorder (ADHD)

United States
Shire

Completed

Lisdexamfetamine Dimesylate (LDX) Pilot Cognition Study to Evaluate the Utility of a Standardized Battery of Tests in Adults With Attention-Deficit Hyperactivity Disorder (ADHD)

Attention-Deficit Hyperactivity Disorder

United States
Shire

Terminated

Adjunctive SPD489 to Antipsychotic Medication in Clinically Stable Adults With Persistent Predominant Negative Symptoms of Schizophrenia

Schizophrenia

United States
Shire

Completed

Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder

Attention-deficit/Hyperactivity Disorder

United States, Canada, Germany, Hungary, Sweden
Shire

Completed

Effectiveness of Vyvanse Compared to Concerta in Adolescents With Attention-deficit/Hyperactivity Disorder

Attention-deficit/Hyperactivity Disorder

United States
Shire

Completed

A Drug Interaction Study of SPD503 and Vyvanse Administered Alone and In Combination in Normal Healthy Volunteers

Healthy

United States
Shire

Terminated

SPD489 Adult Major Depressive Disorder (MDD) Open-label Safety and Tolerability Rollover Extension Study

Major Depressive Disorder

United States, Spain, Germany, Puerto Rico, Canada, Estonia, South Africa, Czechia, Finland, Chile, Hungary, Mexico, Poland, Romania
Shire

Completed

Exploratory Study of SPD489 in Adults With Major Depressive Disorder (MDD) as Augmentation Therapy to an Antidepressant

Major Depressive Disorder

United States
Shire

Withdrawn

SPD489 as Adjunctive Treatment in Adults With Negative Symptoms of Schizophrenia (NSS)

Negative Symptoms of Schizophrenia
Centre hospitalier de l'Université de Montréal...
Canadian Institutes of Health Research (CIHR)

Recruiting

Clinical Trial of High Dose Lisdexamfetamine and Contingency Management in MA Users

Addiction | Methamphetamine-dependence | Addiction, Substance | Methamphetamine Abuse

Canada
Shire

Completed

Efficacy, Safety, and Tolerability of SPD489 in Adults With Schizophrenia and Predominant Negative Symptoms

Schizophrenia and Predominant Negative Symptoms

United States
Medical University of Lodz
Medical University of Silesia; Medical University of Gdansk; Institute of Medical... and other collaborators

Not yet recruiting

Lisdexamphetamine vs Methylphenidate for Pediatric Patients With ADHD and Type 1 Diabetes (LAMAinDiab)

Diabetes Mellitus, Type 1 | Attention Deficit Disorder With Hyperactivity
Shire

Terminated

SPD489 Low Dose and High Dose Ranges When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults With Negative Symptoms of Schizophrenia

Schizophrenia

United States
Shire

Completed

Dose-Optimization Study Evaluating the Efficacy, Safety and Tolerability of Vyvanse (Lisdexamfetamine Dimesylate) in Children Aged 6-12 Diagnosed With ADHD

Attention Deficit Hyperactivity Disorder (ADHD)

United States
Gregory Fabiano

Completed

Efficacy of Lisdexamfetamine Dimesylate for Promoting Occupational Success in Young Adults With ADHD

Attention Deficit Disorder With Hyperactivity

United States
Shire

Completed

Safety and Efficacy of Vyvanse in Adults With Attention-Deficit/Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder

United States
NYU Langone Health
Shire

Completed

Effectiveness and Duration of Effect of Open Treatment in Attention Deficit Hyperactivity Disorder (ADHD) Patients Treated With Lisdexamfetamine Dimesylate(Vyvanse)

Attention Deficit Hyperactivity Disorder

United States
Clinical Study Centers, LLC
Shire

Completed

Effect of Vyvanse on Sleep in Children Aged 6-12 Years With Attention Deficit Hyperactivity Disorder (ADHD)

Sleep | Attention Deficit Hyperactivity Disorder

United States
Kimberley Lakes
Shire

Completed

The Effects of Vyvanse(TM) on Brain Hemodynamics and Reading (VBHR)

Attention Deficit/Hyperactivity Disorder

United States
New River Pharmaceuticals
Shire

Completed

An Open-label Study of NRP104 in Adults With Attention Deficit Hyperactivity Disorder (ADHD)

Attention Deficit Hyperactivity Disorder | Attention Deficit Disorders With Hyperactivity | Attention Deficit Hyperactivity Disorders

United States
University Health Network, Toronto
Shire

Completed

To Evaluate the Safety and Metabolic Profile of Vyvanse for the Treatment of ADHD in Euthymic Adults With Bipolar I/II Disorder

Bipolar Disorder | Attention Deficit/Hyperactivity Disorder

Canada
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Enrolling by invitation

Pharmacological and Behavioral Treatment After Bariatric Surgery: Medication Change for Non-Responders (Stage 2b)

Loss-of-control Eating | Obesity/Overweight

United States
Shire

Completed

A Classroom Study to Assess the Time of Onset of Vyvanse (Lisdexamfetamine Dimesylate) in Pediatric Subjects Aged 6-12 With Attention Deficit/Hyperactivity Disorder (ADHD)

ADHD

United States
Shire

Completed

SPD489 in Adults With Persistent Executive Function Impairments (EFI) and Partial or Full Remission of Recurrent Major Depressive Disorder

Major Depressive Disorder

United States
Shire

Completed

Safety and Tolerability Study of SPD489 in Preschool Children Aged 4-5 Years, Diagnosed With Attention-deficit/Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder (ADHD)

United States
Shire

Completed

Safety and Efficacy Study in Preschool Children Aged 4-5 Years With Attention-deficit/Hyperactivity Disorder (ADHD)

Attention Deficit Hyperactivity Disorder (ADHD)

United States
Rhodes Pharmaceuticals, L.P.
Purdue Pharma LP

Completed

A Comparison of PRC-063 and Lisdexamfetamine in the Driving Performance of Adults With ADHD

Attention Deficit Hyperactivity Disorder

United States
New York State Psychiatric Institute

Completed

Pilot Study of Vyvanse™ In ADHD Adolescents at Risk for Substance Abuse

Attention Deficit Hyperactivity Disorder
New York State Psychiatric Institute
Columbia University; Shire; American Academy of Child Adolescent Psychiatry.

Completed

An fMRI Study of Stimulant vs. Non-Stimulant Treatment of ADHD

Attention Deficit Hyperactivity Disorder

United States
Mclean Hospital
Shire

Completed

Lisdexamfetamine Dimesylate in Residual Symptoms and Cognitive Impairment in Major Depressive Disorder.

Major Depressive Disorder

United States
Shire

Completed

Efficacy and Safety Study of SPD489 in Combination With an Antidepressant in the Treatment of Adults With Major Depressive Disorder

Major Depressive Disorder

United States, Spain, Canada, Puerto Rico, Croatia, Mexico
Duke University
Shire

Terminated

Vyvanse and Glucose Intolerance in Children With Attention Deficit Hyperactivity Disorder (ADHD) and Obesity

Obesity | Glucose Intolerance | Attention Deficit Hyperactivity Disorder

United States

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