Search clinical trials for: MCLA-158

Total 3326 results

Merus N.V.
Chiltern International Inc.; Q2 Solutions; Oncology Therapeutic Development (OTD) and other collaborators

Recruiting

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

Gastric Cancer | Colorectal Cancer | NSCLC | Head and Neck Squamous Cell Carcinoma | HNSCC | Advanced/Metastatic Solid Tumors | Gastroesophageal-junction Cancer

United States, Spain, Belgium, France, Netherlands, United Kingdom
Merus N.V.

Recruiting

A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy)

NSCLC Harboring NRG1 Fusion | Solid Tumours Harboring NRG1 Fusion | Pancreatic Cancer Harboring NRG1 Fusion | NRG1 Fusion

Spain, France, Israel, Belgium, Denmark, United States, Korea, Republic of, Japan, Germany, Netherlands, Austria, Canada, Italy, Norway, Singapore, Sweden, Taiwan, United Kingdom
Essilor International

Active, not recruiting

Comparison of Efficacy Between Two Myopia Control Lenses

Myopia

Singapore
Merus N.V.

Available

Early Access Program Providing HER2/HER3 Bispecific Antibody, MCLA-128, for a Patient With Advanced NRG1-Fusion Positive Solid Tumor

Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Prostate Cancer | Non Small Cell Lung Cancer | Cholangiocarcinoma | Solid Tumor, Unspecified, Adult | Unknown Primary Tumors | NRG1 Fusion
Betta Pharmaceuticals Co., Ltd.

Recruiting

Study of MCLA-129, a Human Bispecific EGFR and cMet Antibody, in Patients With Advanced NSCLC and Other Solid Tumors

Head and Neck Cancer | Colorectal Cancer | Non-Small Cell Lung Cancer | Solid Tumor

China
Merus N.V.
Incyte Corporation

Recruiting

A Study of Bispecific Antibody MCLA-145 in Patients With Advanced or Metastatic Malignancies

Advanced Cancer | Solid Tumor, Adult | B-cell Lymphoma, Adult

United States, Spain, Belgium, Netherlands
ThinkWell
London School of Hygiene and Tropical Medicine

Completed

Effects of the Use of Multi Criterion Decision Analysis (MCDA) on Decision Quality in an Online Delphi (Delphi-MCDA)

Behavioral Changes

United Kingdom
Duke University
National Cancer Institute (NCI)

Completed

Mila Blooms Intervention Study

Childhood Cancer

United States
Mila (bMotion Technologies)

Completed

Rhythm Training of a Serious Game on the Reading Skills of Children w/ a Specific Learning Disorder Impacting Reading

Dyslexia | Learning Disabilities | Learning Disorder, Specific | Specific Learning Disorder, With Impairment in Reading

France
Hospices Civils de Lyon

Withdrawn

Monitoring of Corticosteroids Induced Immunosuppression Using Monocyte Human Leukocyte Antigen-DR (mHLA-DR). (HLA-DR)

Immunosuppression
Stanford University

Recruiting

CogT pSOPT Intervention Study

Mild Cognitive Impairment | Subjective Cognitive Impairment

United States
Betta Pharmaceuticals Co., Ltd.

Not yet recruiting

Study of MCLA-129 Combined With Befotertinib in the Treatment of Advanced Non-small Cell Lung Cancer With EGFR Sensitive Mutation

Non-Small Cell Lung Cancer、EGFR Sensitive Mutation

China
Azienda Ospedaliera Brotzu

Completed

Cheese Intake and Hypercholesterolemia

Hypercholesterolemia
Travere Therapeutics, Inc.

Enrolling by invitation

A Phase 3 Long-term Extension Study to Assess the Long-term Safety and Efficacy of Pegtibatinase Treatment in Participants ≥12 to ≤65 Years of Age With Classical Homocystinuria (HCU) (ENSEMBLE)

Homocystinuria

United States
AEterna Zentaris
AGO Study Group

Completed

Antitumoral Activity and Safety of AEZS-108 in Women With LHRH Receptor Positive Gynecological Tumors

Ovarian Cancer | Endometrial Cancer

Bulgaria, Germany
Massachusetts General Hospital
National Institute on Minority Health and Health Disparities (NIMHD); University...

Completed

Comparative Effectiveness Research for Eliminating Disparities (CERED)

Depression

Puerto Rico, United States
Wroclaw University of Health and Sport Sciences
University of Silesia in Katowice; Jan Dlugosz University in Czestochowa

Completed

Mindfulness for Mothers of Children With Disabilities

Caregiver Burnout | Parental Burnout

Poland
Bridor

Completed

Bread Daily Intake Enriched With Mix Fibers in Metabolic Subjects: Intestinal Microbiota and Metabolic Profile Impact (Breath)

Healthy Obesity, Metabolically

France
Shanghai Leadingtac Pharmaceutical Co., Ltd.

Not yet recruiting

A Single and Multiple Ascending Dose Trial of LT-002-158 in Healthy Adult Volunteers

Atopic Dermatitis | Healthy Volunteer | Hidradenitis Suppurativa
Fundacion Clinic per a la Recerca Biomedica
Polymun Scientific GmbH

Recruiting

Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Protein SOSIP v8.2 763 Vaccine, Adjuvanted With MPLA Liposomes, in Healthy, HIV-Uninfected Adults (HIVAC-FOUND)

Healthy

Spain
ANRS, Emerging Infectious Diseases
University College London Hospitals; Imperial College London; Medical Research... and other collaborators

Active, not recruiting

A Prophylactic HIV Vaccine Trial to Evaluate the Safety and Immunogenicity of HIV Clade C DREP Alone and in Combination With a Clade C ENV Protein in Healthy HIV-uninfected Adults

Healthy Adults

United Kingdom, Switzerland, France
University of Rochester

Completed

HARP-Project 1 Cognitive Training

Aging | Social Isolation

United States
Beni-Suef University
Cairo University

Unknown

Serum Ferritin Concentration and Fetal MCA Doppler as Predictors for Preterm Delivery (SFMCA)

Preterm Delivery

Egypt
Shanghai Minimally Invasive Surgery Center

Unknown

Comparative Study of Medial-to-Lateral Approach vs Dorsal and Medial Hybrid Approach in Laparoscopic Right Hemicolectomy

Postoperative Complications | Overall Survival

China
Dartmouth-Hitchcock Medical Center
National Cancer Institute (NCI)

Terminated

A Molecular Pharmacodynamic Dose-titration Trial of Conjugated Linoleic Acid (CLA; Clarinol®) in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
Advanced Cancer Therapeutics

Unknown

Phase 1 Safety Study of ACT-PFK-158, 2HCl in Patients With Advanced Solid Malignancies

Cancer

United States
Cutera Inc.

Completed

Evaluation of the Cutera Enlighten™ Laser With Micro-Lens Array (MLA) Handpiece Attachment

Acne | Scarring

United States
Artax Biopharma Inc

Recruiting

Proof of Concept Study of AX-158 in Patients With Mild to Moderate Plaque Psoriasis

Psoriasis | Plaque Psoriasis

United Kingdom
Artax Biopharma Inc
Simbec-Orion Group

Completed

A Study of the Safety, Tolerability, Pharmacokinetics and Food Effect After Single and Multiple Ascending Oral Doses

Autoimmune Diseases

United Kingdom
Wageningen University
VU University of Amsterdam

Completed

Health Effects of CLA Versus Industrial Trans Fatty Acids (CLARINeT)

Healthy

Netherlands
Instituto de Investigação em Imunologia
Butantan Institute

Unknown

Clinical Trial of a Therapeutic Vaccine With NY-ESO-1 in Combination With the Adjuvant Monophosphoryl Lipid A (MPLA)

Cancer. | Melanoma. | Ovarian Cancer. | Lung Cancer.

Brazil
Merus N.V.

Recruiting

A Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR and Anti-c-MET Bispecific Antibody, in Patients With Advanced NSCLC and Other Solid Tumors

Gastric Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Non-Small Cell Lung Cancer Metastatic

United States, Spain, France, Italy, Netherlands, Belgium, Korea, Republic of, Germany, Singapore
United States Department of Agriculture (USDA)

Completed

Effect of Trans Fatty Acids From Ruminant Sources on Risk Factors for Cardiovascular Disease

Cardiovascular Disease

United States
McGill University

Completed

Effect of Dietary Conjugated Linoleic Acid (CLA) on Parathyroid Hormone in Men

Healthy

Canada
Johnson & Johnson Consumer Inc. (J&JCI)

Completed

A Study to Evaluate the Efficacy of Investigational OTC Eye Drops

Ophthalmic Solutions

United States
Rigshospitalet, Denmark
Slagelse Hospital; Technical University of Denmark

Recruiting

Human-AI Collaborative Intelligence for Improving Fetal Flow Management

Healthy

Denmark
Alexandre Guedes Torres
Rio de Janeiro State University

Completed

CLA Metabolism and Effects on Human Health

Inflammation | Body Composition, Beneficial | Dietary Modification

Brazil
Azienda Ospedaliera Brotzu
University of Cagliari

Completed

Cheese Intake,CLA and Hypercholesterolemia (CASU)

Modifications of LDL Cholesterol | Modifications of Enocannabinoid Levels

Italy
Alexandru Eniu
Iuliu Hatieganu University of Medicine and Pharmacy

Completed

BRCA1 and BRCA2 Mutation in Romanian Population: a Study of Genotype - Phenotype Correlation at Diagnosis With Prospective Disease Outcome and Survival

To Determine the Prevalence, Penetrance of BRCA1 and BRCA2 Mutations in Romanian Womens With Breast or Ovarian Cancer

Romania
Merus N.V.

Active, not recruiting

MCLA-117 in Acute Myelogenous Leukemia

Acute Myeloid Leukemia | Acute Myelogenous Leukemia

United States, Italy, Netherlands, Belgium, France
University of Utah

Terminated

Multi-Tracer Positron Emission Tomography in Patients With Solid Tumors

Malignant Neoplasm

United States
Indonesia University
BASF

Recruiting

Conjugated Linoleic Acid on Body Weight and Body Fat Mass for 12 Weeks (CLAPSProject)

Body Weight | Overweight and Obesity

Indonesia
Ohio State University
Cognis

Completed

Supplementation With Conjugated Linoleic Acid (CLA) as Complementary Therapy in the Management of Type 2 Diabetes Mellitus (Women's Diabetes Study) (WDS)

Diabetes Mellitus

United States
Imperial College London

Completed

Clinical Trial of HIV Vaccine Combinations in Healthy Men and Women (Ad4HIV)

Human Immunodeficiency Virus

United Kingdom
Universidade Estadual de Londrina

Completed

Conjugated Linoleic Acid in Obese Women (CLA)

Obesity | Lipid Metabolism Disorders

Brazil
Wageningen University
VU University of Amsterdam

Completed

Effect of Conjugated Linoleic Acid Intake on Liver and Kidney Function

Healthy

Netherlands
VA Office of Research and Development
National Cancer Institute (NCI); Jonsson Comprehensive Cancer Center

Terminated

A Vaccine Trial for Patients With Stage IIIB, IV, or Recurrent Non-Small Cell Lung Cancer (VTNSCLC)

Non-Small Cell Lung Cancer (NSCLC)

United States
Merus N.V.

Recruiting

Study Evaluating Zenocutuzumab in Patients With or Without Molecularly Defined Cancers

Metastatic Castration-resistant Prostate Cancer | NSCLC Harboring NRG1 Fusion

United States
Scynexis, Inc.

Completed

Open-Label Study to Evaluate the Efficacy and Safety of Oral Ibrexafungerp (SCY-078) in Patients With Candidiasis Caused by Candida Auris (CARES) (CARES)

Candidemia | Candidiasis, Invasive

Pakistan, India, United States, South Africa
AEterna Zentaris
University of Miami; University of Miami Sylvester Comprehensive Cancer Center and other collaborators

Terminated

A Phase I/II Trial of AEZS-108 in Urothelial Cancer Patients Who Failed Platinum-chemotherapy

Urothelial Carcinoma

United States

Search clinical trials for: MCLA-158

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in France

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations