Search clinical trials for: MEK inhibitor MEK162
Total 65632 results
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Array Biopharma, now a wholly owned subsidiary...CompletedMetastatic Colorectal Cancer | Advanced Solid Tumors | Advanced or Metastatic Biliary CancerUnited States
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Jonsson Comprehensive Cancer CenterNational Cancer Institute (NCI)WithdrawnRecurrent Melanoma | Stage IV MelanomaUnited States
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PfizerTerminatedLow-grade Serous Ovarian Cancer | Low-grade Serous Fallopian Tube Cancer | Low-grade Serous Peritoneal CancerUnited States, Canada, Hungary, Spain, Belgium, France, United Kingdom, Australia, Czechia, Netherlands, Sweden, Italy, Denmark, Germany, Austria, Finland, Ireland, Norway, Poland
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Spirita Oncology, LLCTerminatedAML | MDS | CMMLUnited States
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PfizerCompletedBRAF or NRAS Mutant Metastatic MelanomaUnited States, Netherlands, Italy, Germany, Switzerland
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Array Biopharma, now a wholly owned subsidiary...CompletedAdvanced Solid TumorJapan
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Array Biopharma, now a wholly owned subsidiary...CompletedFallopian Tube Cancer | Epithelial Ovarian Cancer | Peritoneal CancerUnited States
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Array Biopharma, now a wholly owned subsidiary...WithdrawnCardiomegalyUnited States, United Kingdom
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PfizerCompletedSolid Tumor and Hematologic MalignanciesUnited States
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PfizerCompletedLocally Advanced or Metastatic NRAS Mutant MelanomaUnited States, Australia, Germany, Italy, Netherlands
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Array Biopharma, now a wholly owned subsidiary...CompletedAdvanced Solid Tumors | Selected Solid TumorsUnited States, Germany, Canada, Spain, Netherlands, Singapore, Switzerland
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Array Biopharma, now a wholly owned subsidiary...CompletedAdvanced Solid TumorsUnited States, Spain, Canada, Norway, Switzerland
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Array BioPharmaCompletedAML | Advanced and Selected Solid Tumors | High Risk and Very High Risk MDSUnited States, Australia, Italy, Spain, France, Switzerland, United Kingdom
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PfizerTerminatedMetastatic Pancreatic Adenocarcinoma | BRAF Mutated MelanomaUnited States, Australia, Belgium, Canada, France, Italy, Spain, United Kingdom
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Array Biopharma, now a wholly owned subsidiary...TerminatedUveal MelanomaUnited States, France, Germany, Netherlands, Spain, United Kingdom
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PfizerCompletedSolid Tumors Harboring a BRAF V600 MutationUnited States, France, Italy, Singapore, Australia, Spain, Switzerland, Canada, Belgium
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Memorial Sloan Kettering Cancer CenterPlexxikon; Array BioPharmaCompletedGastrointestinal Stromal Tumor (GIST)United States
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University of Heidelberg Medical CenterGerman Cancer Research Center; University Hospital Heidelberg; Array BioPharma; Coordinating Centre for Clinical Trials HeidelbergActive, not recruitingRelapsed or Refractory Multiple Myeloma | Patients With BRAFV600 E or BRAFV600K MutationGermany
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Array Biopharma, now a wholly owned subsidiary...TerminatedHepatic ImpairmentUnited States
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H. Lee Moffitt Cancer Center and Research InstituteArray BioPharmaCompletedNon-Small Cell Lung Cancer | Lung CancerUnited States
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CStone PharmaceuticalsCompletedSolid Tumor, AdultAustralia
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National Cancer Institute (NCI)Active, not recruitingHematopoietic and Lymphoid Cell Neoplasm | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple MyelomaUnited States
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Memorial Sloan Kettering Cancer CenterArray BioPharmaCompletedAdvanced BRAF Mutant CancersUnited States
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SpringWorks Therapeutics, Inc.AvailableNeurofibromatosis Type 1-Associated Plexiform Neurofibromas | Histiocytic Neoplasm | Other MAP-K Pathway Driven Diseases
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Jiangsu HengRui Medicine Co., Ltd.Unknown
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City of Hope Medical CenterNational Cancer Institute (NCI); Array BioPharmaCompletedRecurrent Colon Cancer | Recurrent Rectal Cancer | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal CancerUnited States
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Seoul National University HospitalCompletedBiliary Tract CancerKorea, Republic of
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Novartis PharmaceuticalsCompletedAdenocarcinoma Lung Cancer; Squamous Cell Lung CarcinomaChina
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UNC Lineberger Comprehensive Cancer CenterGlaxoSmithKlineCompletedUnresectable Melanoma | Stage IV Melanoma | Stage III Melanoma | BRAF Mutant MelanomaUnited States
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Array Biopharma, now a wholly owned subsidiary...Completed
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Dana-Farber Cancer InstitutePfizer; Array BioPharmaActive, not recruiting
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University of UtahPfizerCompletedAdvanced KRAS Positive Metastatic Colorectal CancerUnited States
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Array Biopharma, now a wholly owned subsidiary...Completed
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Henan Cancer HospitalRecruitingDigestive System TumorsChina
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PfizerCompletedSolid Tumor | Unspecified Adult Solid Tumor, Protocol SpecificUnited States, Australia, Canada, France, Spain
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Mayo ClinicNational Cancer Institute (NCI)CompletedMetastatic Triple-Negative Breast Carcinoma | Stage IV Breast Cancer AJCC v6 and v7 | Stage III Breast Cancer AJCC v7 | Stage IIIA Breast Cancer AJCC v7 | Stage IIIB Breast Cancer AJCC v7 | Stage IIIC Breast Cancer AJCC v7 | Breast AdenocarcinomaUnited States
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PfizerCompletedMelanomaUnited States, Australia, Canada, Germany, Italy, Netherlands, Spain, Switzerland, United Kingdom
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Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)TerminatedMetastatic Pancreatic Carcinoma | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Recurrent Pancreatic Carcinoma | Locally Advanced Pancreatic CarcinomaUnited States
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University Hospital, CaenActive, not recruiting
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National Cancer Institute (NCI)Completed
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Array Biopharma, now a wholly owned subsidiary...CompletedRheumatoid ArthritisBrazil, Argentina, United States, Poland, Hungary, Peru, Romania
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PfizerActive, not recruitingMelanomaCanada, Spain, United States, Germany, Korea, Republic of, Australia, Czechia, Netherlands, France, Hungary, United Kingdom, Switzerland, Singapore, Russian Federation, Italy, Japan, Israel, Brazil, Portugal, Mexico, Greece, Argen... and more
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University of California, San FranciscoArray BioPharmaRecruitingMelanoma Stage IV | Melanoma Stage IIIUnited States
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Atriva Therapeutics GmbHSGS Life Sciences, a division of SGS Belgium NVCompleted
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Bruno C. MedeirosNational Cancer Institute (NCI)TerminatedRecurrent Adult Acute Myeloid Leukemia | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia Without Maturation... and other conditionsUnited States
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University of California, San FranciscoTakeda; Array BioPharmaTerminatedProgressive Disease | Stage IV Lung Cancer | Lung Non-Small Cell Carcinoma | ROS1 Gene Rearrangement | ALK Gene Rearrangement | Stage IIIB Lung Cancer | Stage IIIC Lung Cancer | Stage IVA Lung Cancer | Stage IVB Lung CancerUnited States
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PfizerCompletedMetastatic Colorectal CancerBelgium, Canada, France, Spain, United States, Italy, Netherlands
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University of California, DavisNational Cancer Institute (NCI); Merck Sharp & Dohme LLC; NovartisActive, not recruitingKRAS Gene Mutation | Stage IV Non-Small Cell Lung Cancer AJCC v7 | Recurrent Non-Squamous Non-Small Cell Lung Carcinoma | Metastatic Non-Squamous Non-Small Cell Lung CarcinomaUnited States
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National Cancer Institute (NCI)CompletedRefractory Plasma Cell Myeloma | Recurrent Plasma Cell MyelomaUnited States
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National Cancer Institute (NCI)CompletedStage IV Skin Melanoma | Recurrent Melanoma | Stage III Skin MelanomaUnited States