Search clinical trials for: MPL-005

Total 4411 results

ChemRar Research and Development Institute, LLC

Completed

А Dose-finding Study to Assess the Efficacy and Safety of CD-008-0045 in Patients With Generalized Anxiety Disorder

Anxiety Disorder Generalized

Russian Federation
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

Clinical Trial for Advanced or Metastatic Pancreatic Cancer

Pancreas Cancer
Hutchison Medipharma Limited

Completed

Phase I Clinical Trial in Healthy Male Volunteers

Inflammatory Bowel Diseases
Sun Yat-sen University

Completed

577nm Micropulse Laser Versus 532nm Subthreshold Laser Photocoagulation for Diabetic Macular Edema

Diabetic Macular Edema

China
Allergy Therapeutics

Completed

Efficacy and Safety/Tolerability of Grass MATA MPL

Type I Hypersensitivity

United States, Canada, United Kingdom, Austria
GlaxoSmithKline

Completed

Immunogenicity and Safety of an Adjuvanted HBV Vaccine Compared to Engerix™-B, in a Non-responder Population ≥ 15y

Hepatitis B
GlaxoSmithKline

Completed

Immunogenicity and Safety of a Novel Adjuvanted HBV Vaccine in Healthy Volunteers Positive for the HLA-DQ2 Genotype

Hepatitis B
Hutchmed

Active, not recruiting

Human Mass Balance of [14C]HMPL-523 in Healthy Adult Male Chinese Subjects

Imumune Thrombocytopenia(ITP) Human Mass Balance

China
Bispebjerg Hospital

Completed

Pretreatments of the Skin Prior to PDT

Healthy
EyeGene Inc.
Novotech (Australia) Pty Limited

Active, not recruiting

Study to Assess the Safety, Tolerability and Explore the Immunogenicity of EG-COVID and EG-COVARo in Healthy Adult Volunteers

COVID-19 Vaccine

Australia
Eleven Biotherapeutics

Completed

A Multi-Center Environmental Study for the Treatment of Moderate to Severe Ocular Allergic Conjunctivitis (EBI-005-AC-2)

Allergic Conjunctivitis (AC)

United States
Hutchison Medipharma Limited
Sun Yat-sen University; Fudan University

Completed

Study of Fruquintinib in Patients With Metastatic Colorectal Cancer

Colorectal Cancer

China
Hutchison Medipharma Limited
Fudan University; Eighty-One Hospital of People's Liberation Army

Completed

A Phase III Trial Evaluating Fruquintinib Efficacy and Safety in 3+ Line Colorectal Cancer Patients （FRESCO) (FRESCO)

Colorectal Cancer

China
Hutchison Medipharma Limited
Shanghai Chest Hospital

Completed

A Clinical Trial of Fruquintinib in Patients With Advanced Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
Hutchison Medipharma Limited

Completed

A Study of HMPL-689 in Healthy Volunteers

Healthy Volunteers

Australia
Abbott Medical Devices

Terminated

MOre REsponse on Cardiac Resynchronization Therapy With MultiPoint Pacing (MORE CRT MPP)

Heart Failure

Korea, Republic of, Spain, United Kingdom, United States, Netherlands, Lebanon, Singapore, Belgium, France, China, Germany, Israel, Austria, Finland, Canada, Italy, Australia, Malaysia, Sweden, Switzerland, Denmark, India, Saudi Arabia and more
Boston Children's Hospital

Completed

iPod and Other MP3 Players on ICDs and Pacemakers in Children

Heart Block | Bradycardia | Arrhythmia | Tachycardia

United States
Lumenis Be Ltd.

Completed

Effectiveness of Intense Pulsed Light for Improving Dry Eye Syndrome

Dry Eye Syndrome

United States
Aier School of Ophthalmology, Central South University

Unknown

Evaluation of the Efficacy of Intense Pulse Light Combined With Lipiflow in the Treatment of Meibomian Gland Dysfunction

Meibomian Gland Dysfunction
University of Aarhus
Odense University Hospital; Oslo University Hospital; Rigshospitalet, Denmark; Hvidovre... and other collaborators

Completed

Combining TLR9 Agonist With bNAbs for Reservoir Reduction and Immunological Control of HIV (TITAN)

HIV-1-infection

Norway, Denmark, United States, Australia
Gynuity Health Projects

Completed

Assessing the Usability and Clinical Utility of the Congo Red Dot Test: A Survey

Preeclampsia

Mexico
Samsung Medical Center

Withdrawn

Clinical Efficacy of Intense Pulsed Light(IPL) Procedure in Dry Eye Patient

Dry Eye Syndromes

Korea, Republic of
Gynuity Health Projects
International Centre for Diarrhoeal Disease Research, Bangladesh

Completed

Assessing the Usability and Clinical Utility of the Congo Red Dot Test: A Case-control Study

Preeclampsia

Bangladesh, Mexico
Abbott Medical Optics

Completed

Short-Term Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions

Corneal Staining

United States
Matteo Visintin

Unknown

Piezosurgery in the Treatment of Class II Furcation Involvement

Furcation Defects

Italy
Sigilon Therapeutics, Inc.

Withdrawn

Safety and Efficacy of Encapsulated Allogeneic MPS-1 Therapy

MPS I | MPS1-S | MPS1-HS

Brazil, United Kingdom
National Institute of Allergy and Infectious Diseases...

Completed

LEISH-F3 + GLA-SE and the LEISH-F3 + MPL-SE Vaccine

Leishmaniasis

United States
Valo Health, Inc.

Withdrawn

Efficacy and Safety of OPL-0301 Compared to Placebo in Adults With Post-Myocardial Infarction (MI) (RESTORE)

Myocardial Infarction
Abbott Medical Optics

Completed

Comparative Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions

Astigmatism | Myopia | Hyperopia

United States
Duke-NUS Graduate Medical School
World Bank; Ministry of Health, Bahrain; Ministry of Industry and Commerce, Bahrain

Not yet recruiting

Understanding Food Choices in Bahrain

Diet, Healthy
Apollo Therapeutics Ltd

Not yet recruiting

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

Colorectal Cancer | Pancreatic Adenocarcinoma | Ovarian Cancer | Prostate Cancer | Gastric Adenocarcinoma | Cholangiocarcinoma | Triple Negative Breast Cancer | Endometrial Adenocarcinoma | Appendiceal Adenocarcinoma
Hutchmed

Recruiting

The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HMPL-523 in Adult Subjects With Immune Thrombocytopenia (ITP)

Pathologic Processes | Immune System Diseases | Autoimmune Diseases | Hematologic Diseases | Hemorrhage | Hemorrhagic Disorders | Thrombotic Microangiopathies | Purpura | Purpura, Thrombocytopenic | Skin Manifestations | Thrombocytopenia | Purpura, Thrombocytopenic, Idiopathic | Immune Thrombocytopenia | Blood Coagulation... and other conditions

United States, Spain, Norway, Australia, Germany
Aarhus University Hospital

Not yet recruiting

Medial Patellofemoral Ligament Reconstruction in Children - a 2-8 Years Follow-up Study (MPFL)

Medial Patellofemoral Dislocation | Medial Patellofemoral Ligament Reconstruction

Denmark
Hutchmed

Recruiting

A Study of HMPL-415S1 in Patients With Advanced Malignant Solid Tumors

Advanced Malignant Solid Tumors

China
Abbott Medical Devices

Completed

ECGi of SyncAV With MultiPoint Pacing

Cardiac Resynchronization Therapy

United States
Madrigal Pharmaceuticals, Inc.

Completed

Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses of MGL-3196 in Subjects With Varying Degrees of Hepatic Impairment and Healthy Matched Control Subjects

Hepatic Impairment | NASH - Nonalcoholic Steatohepatitis | Cirrhosis, Liver

United States
Hutchison Medipharma Limited

Completed

A Study of HMPL-689 in Patients With Lymphomas Failed of Standard of Care or no Standard of Care Existed

Lymphomas

China
Hutchison Medipharma Limited

Unknown

A Study of HMPL-306 in Patients With IDH1 and/or IDH2 Mutation of Relapsed/Refractory Myeloid Leukemia/Neoplasms

Acute Myeloid Leukemia

China
Harbin Medical University

Unknown

In Vivo EGFR Molecular Classification and Treatment Response

Molecular Imaging

China
Poitiers University Hospital

Completed

Relationships Between Macular Pigment Optical Density and Lacquer Cracks in High Myopic Patients.

High Myopia

France
Myriad Therapeutics, Inc.

Terminated

Phase 1 Clinical Trial MPC-2130 Treatment of Blood Cancers / Refractory Cancer

Cancer

United States
Myrexis Inc.

Completed

Phase 1, Multiple Dose Study of MPC-6827 in Subjects With Refractory Solid Tumors

Refractory Solid Tumors

United States
U.S. Army Medical Research and Development Command

Not yet recruiting

Safety and Immunogenicity Study of Venezuelan Equine Encephalomyelitis (VEE) Vaccine as Booster Vaccine in Adults (VEE)

Venezuelan Equine Encephalomyelitis

United States
Clarunis - Universitäres Bauchzentrum Basel

Recruiting

Different Limb Lengths in Gastric Bypass Surgery (SLIM)

Hypertension | Diabetes Mellitus, Type 2 | Dyslipidemias | Sleep Apnea | Obesity, Morbid

Switzerland
Asieris Pharmaceuticals (AUS) Pty Ltd.

Completed

A Phase I, Two-phase, Crossover Study to Evaluate the Safety, Tolerability and Pharmacokinetics of APL-1501 ER Tablets

Bladder Cancer

Australia
Suzhou Yabao Pharmaceutical R&D Co., Ltd.

Completed

Single-dose/Multiple-doses Incremental Intravenous Injection of SY-005 （Recombinant Human Annexin A5）in Healthy Subjects

Sepsis

China
Allergy Therapeutics

Terminated

Investigation of Efficacy and Safety of Tree MATAMPL,Tree MATA, and Placebo in Patients With Birch-Induced Seasonal Allergic Rhinitis

Type I Hypersensitivity

Canada
GlaxoSmithKline

Completed

Evaluation of Immunogenicity, Reactogenicity and Safety of HBV-MPL Vaccine vs Engerix™-B, in Haemodialysis Patients

Hepatitis B

Belgium
Hutchison Medipharma Limited

Recruiting

Clinical Study of HMPL-653 in Treatment of Advanced Malignant Solid Tumors and TGCT

Advanced Malignant Solid Tumors | TGCT

China
Hutchmed

Recruiting

A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

Isocitrate Dehydrogenase Gene Mutation

Spain, United States

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