Search clinical trials for: MRA (Tocilizumab)

Total 6128 results

Hoffmann-La Roche

Completed

A Study of Tocilizumab in Participants With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Non-Biological Disease-modifying Anti-rheumatic Drugs (DMARDs)

Rheumatoid Arthritis

Montenegro
Hoffmann-La Roche

Completed

A Study to Evaluate the Bioequivalence of Tocilizumab Following Subcutaneous Administration Via an Autoinjector (AI 1000-G2) Versus a Pre-Filled Syringe in Healthy Volunteers

Healthy Volunteer

United States
Hoffmann-La Roche

Completed

A Study Assessing the Safety and Efficacy of Subcutaneous RoActemra/Actemra Alone or in Combination With Non-biologic Antirheumatics in Rhuematoid Arthritis Patients in Latin America With Inadequate Response to Non-biologic Antirheumatic Drugs.

Rheumatoid Arthritis

Brazil, Colombia, Argentina, Dominican Republic, Mexico, Venezuela
Hospital Universitario Ramon y Cajal

Terminated

Efficacy of Tocilizumab in Modifying the Inflammatory Parameters of Patients With COVID-19 (COVITOZ-01) (COVITOZ-01)

Covid19

Spain
Massachusetts General Hospital
heckel medizintechnik GmbH

Suspended

Mild-Intensity Whole Body Hyperthermia (WBH) for Major Depressive Disorder

Major Depressive Disorder

United States
University of Southern Denmark
Odense University Hospital; Sygehus Lillebaelt; Odense Patient Data Explorative... and other collaborators

Terminated

Interleukin-6 Inhibitors and Drug-drug Interactions in Patients With Rheumatoid Arthritis

Arthritis, Rheumatoid | Interaction

Denmark
Beni-Suef University

Completed

Evaluating Tocilizumab for Sever COVID-19 Infection in Breast Cancer vs. Non Cancer Pateints

Breast Cancer

Egypt
Oslo University Hospital
University of Oslo; Norwegian University of Science and Technology; St. Olavs... and other collaborators

Completed

ASSessing the Effect of Anti-IL-6 Treatment in Myocardial Infarction: The ASSAIL-MI Trial (ASSAIL-MI)

Myocardial Infarction | Coronary Disease

Norway
Hoffmann-La Roche

Completed

A Long-Term Extension Study of WA22763 and NA25220 of Subcutaneous RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis

Spain
Hoffmann-La Roche

Recruiting

A Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-tumor Activity of RO7616789 in Advanced Small Cell Lung Cancer and Other Neuroendocrine Carcinomas

Small Cell Lung Cancer | Neuroendocrine Carcinoma

United States, Japan, Denmark, Spain, Poland
Nantes University Hospital

Completed

Monocentric Phase 1 Study With Escalation of Doses of Tocilizumab in Combination With Chemotherapy (Idarubicin and Cytarabine) in Patients With Acute Myeloblastic Leukemia (AML) (Tocilam)

Acute Myeloid Leukemia (AML)

France
Hoffmann-La Roche

Completed

A Long-term Safety Extension Study of Tocilizumab in Brazilian Participants With Rheumatoid Arthritis (RA) Who Completed the Studies ML21530 and MA21488 (RITACT)

Arthritis, Rheumatoid

Brazil
Sanofi
Regeneron Pharmaceuticals

Completed

Single-dose Study to Describe the Safety of Sarilumab and Tocilizumab in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Japan
University Health Network, Toronto
Janssen Inc.

Not yet recruiting

Plan Development for Giving Teclistamab in the Outpatient Setting

Multiple Myeloma | Relapsed Cancer | Refractory Cancer
Hoffmann-La Roche

Terminated

A Study to Evaluate Safety, Pharmacokinetics, and Preliminary Anti-tumor Activity of RO7444973 in Participants With Unresectable and/or Metastatic MAGE-A4-positive Solid Tumors

Solid Tumors

Belgium, United States, Australia, Denmark, Spain, United Kingdom
Assistance Publique - Hôpitaux de Paris
Chugai Pharmaceutical

Completed

Efficacy and Tolerance of Tocilizumab In Takayasu Arteritis (TOCITAKA)

TAKAYASU ARTERITIS

France
Hospices Civils de Lyon

Completed

TOCILIZUMAB IN FIBROUS DYSPLASIA OF BONE (TOCIDYS)

Fibrous Dysplasia of Bone

France
Tao Xin

Not yet recruiting

Establishment and Evaluation of Multimodal Image Recognition System of Glioma Based on Deep Learning

Glioma
University of Texas Southwestern Medical Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Clinical Development of Cancer-Specific MRS Biomarkers in Malignant Gliomas

Malignant Gliomas | Astrocytomas | Oligodendrogliomas

United States
AHS Cancer Control Alberta

Completed

Correlation Between MRS (Magnetic Resonance Spectroscopy) and Tumor Response to Radiation Therapy in Breast Cancer

Breast Cancer

Canada
Eline C. B. Eskes

Recruiting

Magnetic Resonance Spectroscopy in Acid Sphingomyelinase Deficiency (MONACO)

Asmd, Visceral Type

Netherlands
Genentech, Inc.

Recruiting

A Study Evaluating the Safety, Pharmacokinetics, and Activity of the Combination of Cevostamab and Elranatamab in Participants With Relapsed or Refractory Multiple Myeloma (R/R MM)

Relapsed or Refractory Multiple Myeloma

Korea, Republic of, Australia, Israel
Case Comprehensive Cancer Center
The Cleveland Clinic

Not yet recruiting

Development of MRF for Characterization of Brain Tumors After Radiotherapy

Brain Tumor | Brain Metastases | Brain Necrosis

United States
Case Comprehensive Cancer Center

Terminated

Feasibility and Clinically Application of Magnetic Resonance Fingerprinting

Glioma | Brain Tumor | Neurofibromatosis Type 1

United States
Kyowa Kirin Co., Ltd.

Completed

A Clinical Study of KRN321 in Adult Subjects With Myelodysplastic Syndrome

MDS

Japan, Korea, Republic of
Hoffmann-La Roche

Completed

An Efficacy and Safety Study of Subcutaneous Tocilizumab in Combination With Methotrexate (MTX) and as Monotherapy Versus MTX in Participants With Moderate to Severe Rheumatoid Arthritis With Inadequate Response to Current Disease-Modifying Antirheumatic Drug (DMARD) Therapy

Rheumatoid Arthritis

China
University of Cincinnati

Withdrawn

Evaluation of Perforator Phase Contrast Angiography in Developing Surgery Plans for Patients With Breast Cancer Undergoing Breast Reconstruction With Free-Flap Methods After Mastectomy

Mammoplasty Patient

United States
Hoffmann-La Roche

Recruiting

A First-in-Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7507062 in Participants With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United Kingdom, Spain, Germany, Poland, South Africa, Netherlands
Rigshospitalet, Denmark

Completed

Meal-regulated Substrate Metabolism, Influence of Obesity and IL-6

Healthy | Obesity

Denmark
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Patients With Active Polyarticular Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis

Belgium, Canada, United States, United Kingdom, Argentina, Germany, Italy, Russian Federation, Spain, Mexico, Poland, Brazil, Australia, France, Peru
Hoffmann-La Roche

Completed

A Study of Tocilizumab in Combination With Disease-Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Moderate to Severe Active Rheumatoid Arthritis With an Inadequate Response to DMARDs

Rheumatoid Arthritis

Italy
Hoffmann-La Roche

Completed

TORPEDO Study: A Study on Rapid Effect of Tocilizumab in Patients With Rheumatoid Arthritis With an Inadequate Response to Disease-Modifying Antirheumatic Drugs (DMARDs) or Anti-TNF

Rheumatoid Arthritis

France
University of California, Los Angeles

Completed

MRA With Feraheme in HHT

Hereditary Hemorrhagic Telangiectasia

United States
German Cancer Research Center
University Hospital Tuebingen

Terminated

Bispecific PSMAxCD3 Antibody CC-1 in Patients With Squamous Cell Carcinoma of the Lung

Lung Cancer Squamous Cell

Germany
American College of Radiology Imaging Network
National Cancer Institute (NCI)

Completed

Magnetic Resonance Imaging in Women Receiving Chemotherapy for Stage III Breast Cancer (ACRIN 6657)

Breast Cancer

United States
Tel-Aviv Sourasky Medical Center
Amsterdam Rheumatology and Immunology Center

Unknown

Therapeutic Drug Monitoring of Tocilizumab in Rheumatoid Arthritis

Rheumatoid Arthritis | Tocilizumab

Israel
Fundació Institut de Recerca de l'Hospital de la...

Completed

Immunoregulatory Mechanisms of Treg Cells Induced by Tocilizumab

Arthritis,Rheumatoid

Spain
University of Michigan Rogel Cancer Center

Withdrawn

Study of Tocilizumab in Patients With Hepatocellular Carcinoma (HCC) Undergoing Transarterial Chemoembolization (TACE)

Hepatocellular Carcinoma

United States
Hoffmann-La Roche

Completed

A Time to Cardiovascular Event Analysis Comparing Tocilizumab to Other Biologics in Patients With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis
Hoffmann-La Roche

Completed

A Study of RoActemra/Actemra (Tocilizumab) Given Subcutaneously in Combination With Traditional DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis

Rheumatoid Arthritis

Poland, United States, Colombia, Brazil, Canada, South Africa, Spain, Greece, Russian Federation, Switzerland, Thailand, Bulgaria, Israel, Mexico, Hungary, Argentina, Panama, Philippines, Guatemala, Malaysia, Australia, New Zealand
Columbia University
Incyte Corporation

Terminated

Itacitinib and Tocilizumab for Steroid Refractory Acute Graft Versus Host Disease (GVHD)

Graft Vs Host Disease | Steroid Refractory GVHD

United States
Hospital Universitario Dr. Jose E. Gonzalez

Completed

Tocilizumab for Cytokine Release Syndrome Prophylaxis in Haploidentical Transplantation

Cytokine Release Syndrome | Stem Cell Transplant Complications

Mexico
University Hospital, Brest

Completed

Lymphocyte and Cytokine Disturbances in Polymyalgia Rheumatica (TENOR-IMMUNO)

Polymyalgia Rheumatica

France
Hoffmann-La Roche

Terminated

A Study of Tocilizumab (RoActemra/Actemra) in Patients With Ankylosing Spondylitis Who Have Had an Inadequate Response to Previous Tumor Necrosis Factor (TNF) Antagonist Therapy

Spondylitis, Ankylosing

Belgium, Czech Republic, France, Germany, Italy, Spain, United States, Canada, Poland, South Africa, United Kingdom, Australia, Denmark, Netherlands, Bulgaria, India, Lithuania, Brazil, Slovakia
Weill Medical College of Cornell University

Terminated

Phase II Study of Tocilizumab for Patients With Glucocorticoid-refractory Acute GVHD After Allogeneic Hematopoetic Stem Cell Transplant (HSCT)

Glucocorticosteroid Refractory Acute GVHD

United States
M.D. Anderson Cancer Center

Completed

Magnetic Resonance Imaging (MRI) Brachytherapy Applicator Study

Cervical Cancer

United States
Children's Hospital Medical Center, Cincinnati

Terminated

Magnetic Resonance Elastography in Infants (MREI)

Liver Disease
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Completed

TOward the Lowest Effective DOse of Abatacept or Tocilizumab (TOLEDO)

Rheumatoid Arthritis

France
Assistance Publique - Hôpitaux de Paris
Hoffmann-La Roche

Completed

Effect of the Interleukin-6 Receptor Antagonist Tocilizumab in Patients With Hand Osteoarthritis (TIDOA)

Hand Osteoarthritis

France
Rennes University Hospital

Completed

Comparative Study of Non-enhanced Versus Contrast Enhanced MR Angiography in Peripheral Arterial Disease on a 3T MR Scanner. (AngioIRMNative)

Peripheral Arterial Disease

France

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