Search clinical trials for: MTX

Total 2474 results

Vanderbilt University Medical Center

Completed

Validation of the NTX Wireless Patient Monitoring System (TATRC)

Hypertension | Bradycardia | Tachycardia | Hypotension | Desaturation

United States
GlaxoSmithKline

Completed

Study to Evaluate the Efficacy and Safety of GSK3196165 Plus Methotrexate in Subjects With Active Moderate-Severe Rheumatoid Arthritis

Arthritis, Rheumatoid

Ukraine, Bulgaria, Canada, Czechia, Estonia, Germany, Hungary, Italy, Mexico, Poland, Russian Federation, South Africa, Spain, United Kingdom
Japan Clinical Oncology Group
Ministry of Health, Labour and Welfare, Japan

Completed

A Study of 5-FU Versus MTX+5-FU in Gastric Cancer With Peritoneal Metastasis

Neoplasm Metastasis | Gastric Cancer

Japan
Universiti Putra Malaysia

Not yet recruiting

Effectiveness of Protein Supplementation on Frailty Improvement, Muscle Strength and Physical Performance Among Pre-Frail Elderly People

Muscle Weakness | Weight Loss | Frailty | Physical Dependence
Celgene

Recruiting

An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions (INDEPENDENCE)

Primary Myelofibrosis | Myeloproliferative Disorders | Anemia | Myelofibrosis | Post-Polycythemia Vera Myelofibrosis

France, Belgium, Spain, Australia, Canada, United States, Korea, Republic of, Romania, Japan, Israel, Italy, Austria, China, Czechia, Germany, Greece, Ireland, Poland, United Kingdom, Hong Kong, Hungary, Lebanon, Colombia, Argentina, Chile and more
University of Maryland, Baltimore

Active, not recruiting

Vital Pulp Treatment in Primary Teeth

Pulpotomy | Vital Pulp Therapies | Indirect Pulp Cap

United States
CHIR-Net
Technical University of Munich

Terminated

Study to Evaluate if Neoadjuvant Radiotherapy Improves Recurrence Free Survival in Pancreatic Head Cancer (Net-Pac)

Pancreatic Adenocarcinoma

Germany
Bristol-Myers Squibb

Completed

First in Human Study to Determine the Safety, Tolerability and Preliminary Efficacy of an Anti-CXCR4 Antibody in Subjects With Acute Myelogenous Leukemia and Selected B-cell Cancers

Follicular Lymphoma | Chronic Lymphocytic Leukemia | Acute Myelogenous Leukemia | Diffuse Large B-Cell Leukemia

United States
Hadassah Medical Organization

Unknown

Comparative Study of Non-Invasive Mask Ventilation vs Cuirass Ventilation in Patients With Acute Respiratory Failure.

Pneumonia | Chronic Obstructive Pulmonary Disease | Neuromuscular Diseases | Respiratory Insufficiency | Pulmonary Edema

Israel
FeRx

Completed

Magnetic-Targeted Doxorubicin in Treating Patients With Cancer Metastatic to the Liver

Melanoma | Sarcoma | Stomach Neoplasms | Gastrointestinal Neoplasms | Breast Neoplasms | Lung Neoplasms | Liver Neoplasms | Colorectal Neoplasms | Pancreatic Neoplasms | Esophageal Neoplasms | Metastases, Neoplasm | Cholangiocarcinoma

United States, Germany
Ocular Therapeutix, Inc.

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)

Ocular Hypertension | Open Angle Glaucoma

United States
Mario Negri Institute for Pharmacological Research

Terminated

ITACA-S2 (Intergroup Trial in Adjuvant Chemotherapy for Adenocarcinoma of the Stomach) (ITACA-S2)

Gastric Adenocarcinoma

Italy
Eli Lilly and Company

Completed

A Study for Patients With Diabetes Mellitus (IOPA) (IOPA)

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1

China
Tuberculosis Clinical Diagnostics Research Consortium
University of Cape Town

Unknown

Feasibility of a Lateral Flow Urine LAM Test for Diagnosis of Tuberculosis in South Africa

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Miliary

South Africa
MicuRx
Worldwide Clinical Trials

Completed

Single Dose and Multiple Dose Escalation Trial of an Oral Formulation of MRX-4

Safety
Bausch Health Americas, Inc.

Completed

Pharmacokinetics and Bioavailability Comparison of Two Different Formulations of MNTX Tablets

Normal Volunteers

United States
Cosmo Technologies Ltd

Completed

The Safety and Efficacy of Methylene Blue MMX® Modified Release Tablets Administered to Subjects Undergoing Screening or Surveillance Colonoscopy

Colorectal Cancer

United States, Belgium, Canada, Germany, Italy, Lithuania, Netherlands, United Kingdom
Bristol-Myers Squibb

Completed

Comparison Study of MDX-010 (CTLA-4) Alone and Combined With Docetaxel in the Treatment of Patients With Hormone Refractory Prostate Cancer

Prostate Cancer

United States
Cairo University

Recruiting

Clinical Performance and Patient Satisfaction of Cerasmart Versus Lithium Disilicate (E-max) Endocrowns

Endodontically Treated Teeth

Egypt
Jordan University of Science and Technology

Active, not recruiting

Outcome of Full Pulpotomy Using Calcium Silicate Based Materials (pulpotomy)

Carious Teeth

Jordan
KK Women's and Children's Hospital

Active, not recruiting

Post-operative Emesis and Pain Outcomes After Cesarean Delivery (EPOC)

Pain, Postoperative | Cesarean Section | Nausea, Postoperative | Vomiting, Postoperative

Singapore
Boston Scientific Corporation

Completed

Atrial Fibrillation: Canadian Atrial Fibrillation Evaluation (CAFE) Study - (CAFE)

Atrial Fibrillation
Hospital Universitário Clementino Fraga Filho

Completed

Insulin Resistance and Metformin Use on Volume of Benign Thyroid Nodules

Insulin Resistance | Thyroid Nodule

Brazil
Damascus University

Completed

The Clinical Performance of Inlay Zirconia Bridges

Dental Crowns

Syrian Arab Republic
Medical University of Vienna

Completed

Effects of Latanoprost on Choroidal Blood Flow Regulation in Human Subjects

Intraocular Pressure | Ocular Physiology | Regional Blood Flow

Austria
Boehringer Ingelheim

Completed

A Study of Intermittent, High-dose Afatinib to Determine the Maximal Tolerated Dose and Assess Activity of This Dose Against Non-small Cell Lung Cancer With T790M Mutations

Carcinoma, Non-Small-Cell Lung

United States
Takeda

Completed

Effect of Febuxostat on Blood Pressure

Hypertension

United States
University of Guarulhos

Unknown

Metronidazole and Amoxicillin for the Treatment of Type 2 Diabetic Subjects With Periodontitis

Periodontitis

Brazil
Bristol-Myers Squibb

Completed

Study of the Safety of MDX-1342 in Combination With Methotrexate in Patients With Rheumatoid Arthritis (MDX1342-01)

Rheumatoid Arthritis

United States, Hungary, Germany, Ukraine, United Kingdom
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Recruiting

Genetic Testing to Select Therapy for the Treatment of Advanced or Metastatic Kidney Cancer, OPTIC RCC Study

Metastatic Clear Cell Renal Cell Carcinoma | Advanced Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Recruiting

A Phase II Study of Nivolumab + Ipilimumab in Advanced HCC Patients Who Have Progressed on First Line Atezolizumab + Bevacizumab

Unresectable Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IIIA Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Stage IVA Hepatocellular Carcinoma AJCC v8 | Stage IVB Hepatocellular Carcinoma AJCC v8 | BCLC Stage B Hepatocellular Carcinoma and other conditions

United States
Aichi Gakuin University

Unknown

Efficacy of Insulin Lispro Mix 50/50 Therapy

Diabetes Mellitus, Type 2

Japan
Klaus Reither
Radboud University Medical Center; Charite University, Berlin, Germany; Institute... and other collaborators

Recruiting

Tuberculosis Diagnostic Trial of CAD4TB Screening Alone Compared to CAD4TB Screening Combined With a CRP Triage Test, Both Followed by Confirmatory Xpert MTB/RIF Ultra in Communities of Lesotho and South Africa

Tuberculosis

Lesotho, South Africa
Maxinovel Pty., Ltd.

Not yet recruiting

A Study of MAX-40279combined With KN046 in Patients With Advanced / Metastatic Solid Tumors

Advanced / Metastatic Solid Tumors
Oregon Health and Science University
Oregon State University; Oregon Department of Corrections; CODA Inc.; Bridgeway... and other collaborators

Completed

Reducing Overdose After Release From Incarceration (ROAR)

Overdose, Drug

United States
nora mostafa mohammed abo shanady

Completed

Evaluation of Apexogenesis With Human Treated Dentin Matrix in Young Permanent Molars

Dentin Bridge

Egypt
Ocular Therapeutix, Inc.

Completed

To Assess the Efficacy and Safety of OTX-DED for the Short-term Treatment of Signs and Symptoms of Dry Eye Disease

Dry Eye

United States
Ege University

Completed

The Effect of Two Different Root Canal Sealers on Postobturation Pain and Clinical and Radiographical Outcome After Two-year Follow-up

Asymptomatic Vital Mandibular Molar Teeth

Turkey
Foundation for Professional Development (Pty) Ltd
National Institutes of Health (NIH); University of California, Irvine; National... and other collaborators

Completed

Acceptability and Feasibility of Home-based TB Testing

Tuberculosis, Pulmonary | Households

South Africa
Cairo University

Completed

Success Rate of Three Capping Materials

Caries

Egypt
Istanbul University

Completed

Comparison of The Success Rates of Four Different Pulpotomy Techniques

Extensive Decay in Primary Molars
Tahitian Noni International, Inc.
Indonesia University

Completed

Effect of an Iridoid Enriched Beverage on Skin Autofluorescence

Quality of Life | Metabolic Syndrome | Oxidative Stress

Indonesia
Takeda

Terminated

Effect of Febuxostat Compared to Placebo on Exercise Tolerance in Participants With Chronic Stable Angina

Angina

United States
Truth Initiative

Completed

Study of Mobile Phone Support for the DC Tobacco Quitline

Smoking Cessation

United States
MediQuest Therapeutics

Completed

Phase III Study of a Topical Gel Formulation for Treatment and Prevention of Raynaud's Phenomenon

Autoimmune Diseases | Scleroderma | Raynaud's Disease

United States, United Kingdom, Sweden
Johnson & Johnson Vision Care, Inc.

Completed

The Effects of Contact Lenses With UV/HEV-Filter on Visual Function

Visual Acuity

United States
Ain Shams University

Recruiting

US-Guided PECS II Block Versus MTP Block For Postoperative Analgesia Of MRM Sugery

Analgesia | Anesthesia, Local | Post Operative Pain | Neuromuscular Blockade

Egypt
Pharma Holdings AS
CTC Clinical Trial Consultants AB

Recruiting

Study to Evaluate a Single Dose of LTX-109 in Subjects With COVID-19 (Coronavirus Disease 2019) Infection.

COVID-19

Sweden
Peking University Third Hospital
People's Hospital of Guangxi

Recruiting

Prospective Clinical Study of Different Intraocular Lens Implantation Designed for the Correction of Presbyopia

Presbyopia | Cataract Senile

China
University College, London
Merck KGaA, Darmstadt, Germany

Active, not recruiting

EACH: Evaluating Avelumab in Combination With Cetuximab in Head and Neck Cancer (EACH)

Head and Neck Cancer | Squamous Cell Carcinoma

United Kingdom

Search clinical trials for: MTX

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