Search clinical trials for: Masked Saline Placebo

Total 72062 results

Columbia University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

PICU Transfusion Study: Harmful Effects of Red Blood Cell Transfusions

Iron, Abnormal Blood Level

United States
Northwell Health

Withdrawn

Platelet Function With Various Storage Techniques

Platelet Dysfunction Due to Drugs
University of Washington
Bill and Melinda Gates Foundation; University of Witwatersrand, South Africa

Not yet recruiting

BIYELA - Bexsero Immunisation in Young Women in Africa

Gonorrhea | Gonorrhea of Pharynx | Gonorrhea of Anus | Gonorrhea of Cervix

South Africa
ModernaTX, Inc.

Recruiting

Study to Evaluate the Safety, Reactogenicity, and Effectiveness of mRNA-1273.214 SARS-CoV-2 (COVID-19) Vaccine in Infants (BabyCOVE)

SARS-CoV-2

United States
Beijing Northland Biotech. Co., Ltd.

Recruiting

Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-2)

Ischemia | Peripheral Vascular Disease | Arterial Occlusive Disease | Ulcers

China
Vaccitech (UK) Limited
Clinical Network Services (CNS) Pty Ltd

Terminated

Efficacy of Candidate Influenza Vaccine MVA-NP+M1 in Adults

Influenza

Australia
Hellenic Institute for the Study of Sepsis
Radboud University Medical Center

Completed

Bacillus Calmette-guérin Vaccination to Prevent Infections of the Elderly (ACTIVATE)

Mortality | Infection | Hospitalization

Greece
Imperial College London
Medical Research Council; Covance

Completed

Study of the Gut Hormone Analogue G3215 in Adult Subjects

Obesity | Diabetes Mellitus

United Kingdom
Genervon Biopharmaceuticals, LLC
University of California, Los Angeles; Columbia University; University of Louisville and other collaborators

Completed

Efficacy and Safety Study of GM602 in Patients With Acute Middle Cerebral Artery Ischemic Stroke Within 18 Hours (GMAIS)

Stroke

United States
GlaxoSmithKline

Completed

Trial to Assess Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Meningococcal ABCWY Vaccine as Compared to Meningococcal B Vaccine in Adolescents

Infections, Meningococcal

United States, Finland, Poland
New York State Psychiatric Institute
Stanley Medical Research Institute

Completed

Tocilizumab as Add-On Treatment For Residual Positive, Negative, and Cognitive Symptoms of Schizophrenia

Schizophrenia | Schizoaffective Disorder

United States
Pfizer

Completed

Dose Escalation Study of PF-06741086 In Healthy Subjects

Healthy

Belgium
European Vaccine Initiative
University of Oxford; Malaria Research and Training Center, Bamako, Mali

Not yet recruiting

Assessment of Safety, Immunogenicity and Efficacy of R21/Matrix-M1 Malaria Vaccine in Healthy WOCBP in Mali

Healthy Women of Child Bearing Potential
Beijing Northland Biotech. Co., Ltd.

Recruiting

Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-1)

Ischemia | Peripheral Vascular Disease | Arterial Occlusive Disease | Ulcers

China
Universitätsklinikum Hamburg-Eppendorf

Terminated

Adrecizumab (HAM8101) to Improve Prognosis and Outcomes in COVID-19 Trial (AGNES-19)

COVID-19

Germany
Laureate Institute for Brain Research, Inc.

Terminated

Influenza Challenge in Mood Disorders

MAJOR DEPRESSIVE DISORDER

United States
Mayo Clinic

Completed

Effects of Gastric Antral Botulinum Toxin Injections in Obese Subjects

Obesity

United States
University of Louisville

Active, not recruiting

Gentamicin Bladder Instillation in Individuals With Spinal Cord Injury Having Chronic Urinary Tract Infections

Spinal Cord Injuries | Neurogenic Bladder

United States
University of California, San Francisco
Genentech, Inc.

Completed

Web-based Mindfulness Meditation in Reducing Distress in Participants With Metastatic Gastrointestinal Cancer and Their Caregivers

Caregiver | Metastatic Gastrointestinal Carcinoma

United States
University Hospital, Grenoble
AGIR à Dom

Completed

Efficacy and Safety of 3% Hypertonic Saline Inhalation (24h vs 72h) to Treat Acute Bronchiolitis in Hospitalized Infants (BRONDUSAL)

Bronchiolitis

France
Massachusetts General Hospital
Medical University of South Carolina; Brown University; Wake Forest University... and other collaborators

Recruiting

Expanding First-line Options for Depression and Matching Treatments to Patients: Hatha Yoga vs. Behavioral Therapy

Depression

United States
University of North Carolina, Chapel Hill
U.S. National Science Foundation

Recruiting

Body and Social Behavior (BSB)

Inflammation | Psychology, Social | Defeat, Social | Interaction, Social

United States
Qu Biologics Inc.
The National Research Council of Canada Industrial Research Assistance Program

Active, not recruiting

Assessment of QBKPN Site-Specific Immunomodulator Efficacy in Improving Innate Immune Function & Reducing Respiratory Tract Infection Morbidity in Older Adults (RESILIENCE)

Immune Deficiency

Canada
ModernaTX, Inc.

Active, not recruiting

A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1468 in Healthy Adults ≥50 Years of Age

Herpes Zoster

United States, Puerto Rico
Novavax

Completed

Placebo- Controlled Study to Evaluate the Safety and Immunogenicity of the RSV-F Vaccine in Elderly Adults

Respiratory Syncytial Virus (RSV)

United States
Northwestern University
Icahn School of Medicine at Mount Sinai

Completed

The Efficacy and Safety of Secukinumab in Patients With Ichthyoses

Netherton Syndrome | Ichthyosis | Lamellar Ichthyosis | Autosomal Recessive Congenital Ichthyosis | Congenital Ichthyosiform Erythroderma | Epidermolytic Ichthyosis

United States
Dartmouth-Hitchcock Medical Center
Muhimbili University of Health and Allied Sciences

Completed

DAR-901 TB Booster Vaccine to Prevent TB in Adolescents (DAR-PIA)

Tuberculosis

Tanzania
Beijing Northland Biotech. Co., Ltd.

Completed

Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003CLI-II)

Ischemia | Peripheral Vascular Disease | Arterial Occlusive Disease | Ulcers

China
Advanz Pharma

Completed

A Study of the Efficacy and Safety of Vernakalant Hydrochloride (MK-6621) in Patients With Atrial Fibrillation (MK-6621-010 AM4)

Atrial Fibrillation
NYU Langone Health
National Eye Institute (NEI); National Institutes of Health (NIH)

Active, not recruiting

Zoster Eye Disease Study (ZEDS)

Herpes Zoster Ophthalmicus

United States, Canada
Xijing Hospital

Unknown

Long Term Follow-up of Autologous Bone Marrow Mononuclear Cells Therapy in STEMI

Myocardial Infarction

China
Cynthia Wong

Completed

Multimodal Uterotonics at the Time of Cesarean Section in Laboring Patients

Uterine Atony With Hemorrhage

United States
University of Florida

Withdrawn

Oval-8 Splinting Versus Standardized Treatment With Tee Pee or Forearm Based Thumb Spica Splinting (Oval-8)

Carpometacarpal (CMC) Joint Arthritis

United States
Novartis Pharmaceuticals

Completed

A Study to Determine the Capacity of VAK694 When Combined With Allergen Immunotherapy to Bring About Specific Immune Tolerance

Seasonal Allergic Rhinitis

United Kingdom
Institute for the Study of Urological Diseases,...

Not yet recruiting

LiST Plus PRP Injection Therapy vs LiST Monotherapy for ED Treatment

Erectile Dysfunction
American Regent, Inc.

Completed

Placebo-Controlled Study to Investigate the Efficacy & Safety of Injectafer in the Treatment of RLS

Restless Legs Syndrome (RLS)

United States
The University of Texas Health Science Center,...
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Pediatric Autologous Bone Marrow Mononuclear Cells for Severe Traumatic Brain Injury

Traumatic Brain Injury

United States
Tri-Service General Hospital

Completed

The Effect of Hydrodissection for Carpal Tunnel Syndrome

Carpal Tunnel Syndrome

Taiwan
Beth Israel Deaconess Medical Center
Merz Pharmaceuticals

Withdrawn

Incobotulinum Toxin A for Sialorrhea in Parkinson's Disease (PD)/Parkinsonism and Amyotrophic Lateral Sclerosis (ALS) (Xeomin)

Parkinson Disease | Amyotrophic Lateral Sclerosis

United States
Yale University

Completed

Investigation of Efficacy and Safety of Botulinum Toxin A (Botox-Allergan Inc) in Migraine Headaches

Refractory Migraine

United States
Hamilton Health Sciences Corporation

Completed

Fecal Biotherapy for the Induction of Remission in Active Ulcerative Colitis

Ulcerative Colitis

Canada
NYU Langone Health

Not yet recruiting

Packed Red Blood Cell Transfusion During Cardiac Arrest

Cardiac Arrest

United States
İlke Karabıyık

Completed

Nonpharmacological Management of Postoperative Pain in Children

Orthopedic Disorder | Post Operative Pain

Turkey
Shanghai East Hospital
Shanghai iCELL Biotechnology Co., Ltd, Shanghai, China

Not yet recruiting

Precise Transplantation of hAESCs Into the Ventricle for Parkinson's Disease.

Parkinson's Disease

China
Istituto Ortopedico Rizzoli

Recruiting

Hydrolyzed Collagen Formulation vs Placebo in Knee Osteoarthritis

Knee Osteoarthritis

Italy
Reveal Pharmaceuticals Inc.
National Cancer Institute (NCI); Quotient Sciences

Completed

First in Human Study of RVP-001, a New Manganese Based MRI Contrast Agent

Healthy

United States
University of Oxford
Novartis Pharmaceuticals; The TIMI Study Group

Active, not recruiting

A Randomized Trial Assessing the Effects of Inclisiran on Clinical Outcomes Among People With Cardiovascular Disease (ORION-4)

Atherosclerotic Cardiovascular Disease

United Kingdom, United States
Baxalta now part of Shire
DynPort Vaccine Company LLC, A GDIT Company

Completed

Pharmacokinetic (PK) and Safety Study of Plasma-derived Human Butyrylcholinesterase Administered Intravenously

Healthy Volunteers | Chemical Terrorism | Chemical Warfare

United States
The Medicines Company

Completed

Trial to Evaluate the Effect of Inclisiran Treatment on Low Density Lipoprotein Cholesterol (LDL-C) in Subjects With Heterozygous Familial Hypercholesterolemia (HeFH) (ORION-9)

Elevated Cholesterol | Heterozygous Familial Hypercholesterolemia

United States, Canada, Czechia, Denmark, Netherlands, South Africa, Spain, Sweden
Cerenis Therapeutics, SA

Terminated

CER-001 Therapy as a Novel Approach to Treat Genetic Orphan Diseases (TANGO)

Familial Hypoalphalipoproteinemia

France, United States, Belgium, Canada, Israel, Italy, Netherlands

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