Search clinical trials for: Matched Placebo

Total 54193 results

Sansum Diabetes Research Institute

Withdrawn

Role of Pregnancy Related Hormones in Lowering the Insulin Requirement in Pregnant Women With Type 1 Diabetes

Type 1 Diabetes

United States
Icahn School of Medicine at Mount Sinai

Terminated

Doxycycline in Treating Patients With Chronic Rhinosinusitis With Nasal Polyps

Polyp of Nasal Sinus

United States
Sutter Health

Completed

Nuedexta for the Treatment of Adults With Autism (Nuedexta)

Autism

United States
Par Pharmaceutical, Inc.
Novum Pharmaceutical Research Services

Terminated

Bioequivalence of Two Ciprofloxacin 0.3%/Dexamethasone 0.1% Sterile Otic Suspensions in Otitis Media in Children With Tympanostomy Tubes

Otitis Media in Patients With Tympanostomy Tubes

United States
Pearl Therapeutics, Inc.

Completed

Multi-Center Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD (PINNACLE 2)

Chronic Obstructive Pulmonary Disease (COPD)

United States
The First Affiliated Hospital with Nanjing Medical...
National Natural Science Foundation of China

Unknown

Different Platelet Activities Between Intracoronary and Peripheral Blood in Coronary Artery Disease Patients (DPABIAP)

Coronary Artery Disease

China
Merck Sharp & Dohme LLC

Completed

Effect of Rofecoxib and a Narcotic Analgesic to Treat Pain Following Arthroscopic Surgery (0966-179)(COMPLETED)

Pain, Postoperative Arthroscopy
Herbert Lindsley, MD

Completed

Effect of Intraarticular Steroids on Bone Turnover in Osteoarthritis

Osteoarthritis

United States
Orexigen Therapeutics, Inc

Completed

Study to Evaluate the Effect of Naltrexone and Bupropion Extended-Release Combination on Cardiac Repolarization in Healthy Participants

Heart Repolarization

United States
Vanderbilt University

Completed

Comparative Effects of Aspirin and NHP-544C

Healthy

United States
Astellas Pharma Europe B.V.

Completed

First-in-human: Single Ascending Dose, Food Effect, Drug-drug Interaction, Multiple Ascending Dose, Proof of Pharmacology

Healthy Volunteers

United Kingdom, Germany
e-Therapeutics PLC

Completed

Assessment of Single Doses of Oral Dexanabinol in Healthy Subjects

Cancer | Pharmacokinetics | Tolerability | Safety

United Kingdom
Ullevaal University Hospital
University of Oslo

Completed

Analgesic Effect of Paracetamol, Paracetamol + Codeine, Ibuprofen and Their Combination

Pain, Postoperative

Norway
Planned Parenthood League of Massachusetts
Society of Family Planning

Completed

Cervical Preparation Before Dilation and Evacuation

Abortion, Induced

United States
Bristol-Myers Squibb

Completed

Ph II Trial of a Novel Anti-angiogenic Agent in Combination With Chemotherapy for the Second-line Treatment of Metastatic Colorectal Cancer

Colorectal Cancer (CRC)

United States, Argentina, Italy
Vanderbilt University
Forest Laboratories

Completed

Nebivolol in the Supine Hypertension of Autonomic Failure

Hypertension | Multiple System Atrophy | Pure Autonomic Failure

United States
GlaxoSmithKline

Withdrawn

A Study of IV Casopitant for the Prevention of Nausea and Vomiting Caused By Cisplatin-Based Highly Emetogenic Chemotherapy

Cancer | Solid Tumor Cancer | Chemotherapy-Induced Nausea and Vomiting | Nausea and Vomiting

United States, Canada
Boehringer Ingelheim

Completed

Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin in Healthy Male and Female Volunteers

Healthy
Zalicus

Completed

Multicenter Study to Evaluate CRx-102 vs. Each of Its Components to Treat Active Rheumatoid Arthritis (MARS-1)

Rheumatoid Arthritis

United States, Poland, Argentina, Romania, Serbia, Canada, Estonia, Russian Federation, Lithuania, South Africa, Hungary, Mexico
Yale University
VA Connecticut Healthcare System

Completed

The Effect of Cycloserine on Smoking Behavior in Nicotine Dependent Smokers

Smoking

United States
Felipe Melo Cruz

Completed

Vitamin E for Oxaliplatin-induced Peripheral Neuropathy Prophylaxis

Peripheral Neuropathy

Brazil
AGUNCO Obstetrics and Gynecology Centre

Completed

Clinical, Metabolic and Endocrine Effects of the Treatment With Drospirenone and Ethinyl Estradiol Alone or in Combination With Myo-inositol in Young Women With Polycystic Ovary Syndrome (PCOS) and Insulin Resistance

Polycystic Ovary Syndrome | PCOS

Italy
Novartis

Completed

To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucose Tolerance or Patients With Type 2 Diabetes With Differing Baseline Diabetes Therapies

Type 2 Diabetes Mellitus | Impaired Glucose Tolerance

United States, Canada, Finland, Australia, Germany, India, Italy
Hospital de Clinicas de Porto Alegre

Unknown

Efficacy and Safety Assessment of an Anti-Cold Preparation in the Symptomatic Treatment of Common Cold and Flu-Like Syndrome

Common Cold | Flu-like Syndrome

Brazil
University of Southern California
National Cancer Institute (NCI)

Recruiting

Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms

Polycythemia Vera | Essential Thrombocythemia | Myelofibrosis | Myelodysplastic Syndrome | Clonal Cytopenia of Undetermined Significance

United States
Egymedicalpedia

Not yet recruiting

The Effect of Dexmedetomidine, Melatonin and Pregabalin

Endoscopic Sinus Surgery

Egypt
Indonesia University

Not yet recruiting

Preemptive Analgesia Combination of Celecoxib and Pregabalin in THA

Arthroplasty Complications | Pregabalin | Analgetic | Celecoxib
Children's Oncology Group

Recruiting

A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for Primary Central Nervous System Tumors

Central Nervous System Carcinoma

United States, Puerto Rico
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy, Pharmacokinetics, Safety and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant

United States, China
Ultragenyx Pharmaceutical Inc

Terminated

Safety, Tolerability, and Pharmacokinetics of UX053 in Patients With Glycogen Storage Disease Type III (GSD III)

Glycogen Storage Disease Type III

United States, Spain, Italy
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Efficacy and Mechanisms of Naltrexone+Bupropion for Binge Eating Disorder

Binge-Eating Disorder

United States
Axsome Therapeutics, Inc.

Enrolling by invitation

A Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects With Alzheimer's Disease Agitation

Alzheimer Disease | Agitation in Patients With Dementia of the Alzheimer's Type | Agitation, Psychomotor

United States, Canada
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantation

Hematopoietic and Lymphoid Cell Neoplasm | Acute Myeloid Leukemia | Hodgkin Lymphoma | Myelofibrosis | Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Chronic Phase Chronic Myelogenous Leukemia... and other conditions

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)

Breast Cancer

Japan, Poland, United States, Australia, Belgium, Brazil, Canada, China, Colombia, Costa Rica, France, Germany, Hungary, Ireland, Israel, Korea, Republic of, New Zealand, Portugal, Puerto Rico, Russian Federation, Spain, Taiwan, Ukr... and more
University of Pennsylvania

Completed

Stress and Inflammation in Late-Life Depression (S&I)

Depression | Inflammation

United States
Zealand University Hospital

Completed

Combined Intravenous Dexamethasone and Dexmedetomidine as Adjuncts to Popliteal and Saphenous Nerve Blocks in Patients Undergoing Orthopaedic Surgery of the Foot and Ankle (ADJUNCT2)

Anesthesia, Local

Denmark
H. Lundbeck A/S
Takeda

Completed

Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Participants Aged 7 to 11 Years With Major Depressive Disorder (MDD)

Depressive Disorder, Major

Korea, Republic of, United States, Hungary, Poland, Spain, Serbia, Estonia, Bulgaria, Mexico, Russian Federation, Ukraine, Canada, Colombia, France, Germany, Israel, Italy, Latvia, South Africa
Hawler Medical University

Completed

Pentoxifylline as an Adjunct to Citalopram in Adult Patients With Major Depressive Disorder

Major Depressive Disorder

Iraq
University of Washington
Bill and Melinda Gates Foundation

Terminated

Treatment for COVID-19 in High-Risk Adult Outpatients

COVID-19 | SARS-CoV-2

United States
YingHsuanTai

Withdrawn

Multi-Strategy Intervention for Anesthesia Care of Obese Patients A Factorial Randomized Controlled Trial

Obesity | Bariatric Surgery Candidate | Tracheal Intubation Morbidity | Nausea and Vomiting, Postoperative | Gastric Reflux | Hyperglycemia Drug Induced

Taiwan
Lebanese American University Medical Center

Active, not recruiting

Managing Endothelial Dysfunction in COVID-19 : A Randomized Controlled Trial at LAUMC (MEDIC-LAUMC)

Covid19

Lebanon
Avanir Pharmaceuticals

Completed

Efficacy, Safety and Tolerability Study of AVP-923 (Dextromethorphan/Quinidine) for Treatment of Symptoms of Agitation in Participants With Alzheimer's Disease

Alzheimer's Disease | Agitation

United States
GlaxoSmithKline

Terminated

Dose Finding Study of Nemiralisib (GSK2269557) in Subjects With an Acute Moderate or Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Australia, Argentina, France, Germany, Poland, Romania, Russian Federation, Spain, United States, Netherlands, Sweden, Korea, Republic of, Canada, United Kingdom, Italy, Mexico
Universitaire Ziekenhuizen KU Leuven
AstraZeneca

Active, not recruiting

Circulating Tumor DNA Guiding (Olaparib) Lynparza® Treatment in Ovarian Cancer (CLIO)

Ovarian Epithelial Cancer

Belgium
Gyeongsang National University Hospital
Korea Otsuka Pharmaceutical Co., Ltd.

Unknown

Cilostazol and Endothelial Progenitor Cell (EPISODE)

Myocardial Infarction, Acute
Sanofi
Regeneron Pharmaceuticals

Completed

Evaluation of Dupilumab in Patients With Severe Steroid Dependent Asthma (VENTURE)

Asthma

Belgium, Israel, United States, Mexico, Argentina, Brazil, Canada, Chile, Colombia, Hungary, Italy, Netherlands, Poland, Romania, Russian Federation, Spain, Ukraine
Yuqi Cheng

Unknown

A Prediction Study of Multiple Indexes of the Effect of Different Mechanisms of Antidepressants Treatment on Depression

Major Depressive Disorder | Depression, Unipolar

China
AstraZeneca

Completed

Two-part Pharmacokinetic and Pharmacodynamic Study of LAS190792 in Patients With Asthma and COPD

Asthma | Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
St. Petersburg State Pavlov Medical University

Terminated

Nivolumab With Chemotherapy in Refractory MDS

Myelodysplastic Syndromes

Russian Federation
Andrew Moshfeghi, MD, MBA
Case Western Reserve University

Withdrawn

Evaluation of Bromocriptine, Metoprolol and Tamsulosin in Eyes With Non-Central DME

Diabetic Macular Edema

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