Search clinical trials for: Megestrol acetate and metformin

Total 5974 results

Holland Bloorview Kids Rehabilitation Hospital
The Hospital for Sick Children

Active, not recruiting

Metformin for Motor and Cognitive Improvement in Children With Cerebral Palsy: A Feasibility Study

Cerebral Palsy

Canada
Boston Children's Hospital

Completed

Pilot Study of Metformin for Patients With Fanconi Anemia

Fanconi Anemia

United States
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Efficacy and Safety of SHR3824 in Combination With Metformin in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

China
VA Office of Research and Development
Oregon Health and Science University

Completed

Metformin and Muscle in Insulin-resistant Older Veterans (M&M)

Prediabetes

United States
Hoffmann-La Roche

Completed

A Study of The Effect of Aleglitazar on Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin

Diabetes Mellitus Type 2

Germany
University of California, San Francisco

Completed

Impact of Genetics on Metformin Pharmacokinetics

Other Conditions That May Be A Focus of Clinical Attention

United States
Barts & The London NHS Trust
Barts and the London School of Medicine and Dentistry

Completed

Prevention of Metabolic Complications of Glucocorticoid Excess

Iatrogenic Cushing Disease

United Kingdom
Takeda

Terminated

Safety and Efficacy of TAK-559 in Combination With Metformin in Patients With Type 2 Diabetes Mellitus.

Diabetes Mellitus
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

Hematopoietic and Lymphoid Cell Neoplasm | Anorexia | Advanced Malignant Solid Neoplasm

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess the Bioequivalence of 2 Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) (50 mg/1,000 mg) With Respect to the Individual Components of Canagliflozin (1 x 100 mg) and Metformin IR Tablets (2 x 1,000 mg) in Healthy Volunteers

Healthy

United States
Duke University

Terminated

Metformin for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) (NAFLD)

Fatty Liver

United States
Medical University of Bialystok
Medical Research Agency, Poland

Not yet recruiting

Clinical Trials Evaluating the Effect of Metformin Treatment on Function Endometrium in Women Diagnosed With Idiopathic Infertility (METIN)

Infertility, Female
National University of Ireland, Galway, Ireland
Health Research Board, Ireland; University Hospital of Limerick; University College... and other collaborators

Completed

A Randomized Placebo Controlled Trial of the Effectiveness of Metformin in Addition to Usual Care in the Reduction of Gestational Diabetes Mellitus Effects (EMERGE)

Gestational Diabetes

Ireland
Maria Sandberg Westerstahl

Terminated

Effect of Exercise or Metformin on Nocturnal Blood Pressure and Other Risk Factors for CVD Among Obese Adolescents

Cardiovascular Diseases

Sweden
National Cancer Institute (NCI)

Completed

Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI

Obesity | Colorectal Cancer | Adenomatous Polyp

Canada, United States
Massachusetts General Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Unknown

Metformin Treatment in Polycystic Ovary Syndrome (PCOS)

Polycystic Ovary Syndrome
University of Hawaii
National Institute of General Medical Sciences (NIGMS)

Unknown

Metformin for HIV Inflammation

Coronary Artery Disease | HIV

United States
Torrent Pharmaceuticals Limited

Completed

Study to Evaluate the Bioequivalence of a Test Tablet Formulation of Metformin HCl (1000 mg), Compared to an Equivalent Dose of a Commercially Available Reference Drug Product (Glucophage®, Bristol-Myers Squibb Company) in Fasted, Healthy, Adult Subjects

Healthy

United States
Torrent Pharmaceuticals Limited

Completed

Study to Evaluate the Bioequivalence of a Test Tablet Formulation of Metformin HCl (1000 mg), Compared to an Equivalent Dose of a Commercially Available Reference Drug Product (Glucophage®, Bristol-Myers Squibb Company) in Fed, Healthy, Adult Subjects

Healthy

United States
GlaxoSmithKline

Completed

Evaluation of Food Effect on the Pharmacokinetics of Sustained Release Metformin in Healthy Indian Volunteers

Diabetes Mellitus, Type 2
Columbia University

Recruiting

Metformin in Heart Failure Without Diabetes (Met-HeFT)

Heart Failure

United States
Canadian Cancer Trials Group
National Cancer Institute (NCI); ETOP IBCSG Partners Foundation; ICR-CTSU

Completed

A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer

Breast Cancer

United States, Canada, Switzerland, United Kingdom
Shenzhen People's Hospital

Unknown

Effect of Metformin as add-on Therapy on Glycemic Control and Other Outcomes in Type 1 Diabetes

Type 1 Diabetes Mellitus | Metformin

China
Hoffmann-La Roche

Completed

A Study of RO5095932 in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus Type 2

United States
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Monotherapy

Diabetes Mellitus Type 2

Korea, Republic of, China
Boehringer Ingelheim

Completed

Relative Bioavailability of Multiple Oral Doses of BI 187004 and Metformin After Co-administration Compared to Multiple Oral Doses of BI 187004 Alone and Metformin Alone in Healthy Male Subjects

Healthy

Germany
Children's Hospital Los Angeles

Terminated

Metformin and Transient Hyperglycemia

Hyperglycemia | Diabetes Mellitus | Insulin Resistance | Acute Lymphoblastic Leukemia

United States
GlaxoSmithKline

Completed

AVANDAMET Versus Metformin And Sulphonylurea In People With Poorly Controlled Type 2 Diabetes

Non-Insulin-Dependent Diabetes Mellitus

Spain, Germany, Belgium, United Kingdom, Ireland, Netherlands, Italy, France, Mexico, Switzerland, Lithuania
Woman's
Novo Nordisk A/S

Completed

Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)

Type 2 Diabetes Mellitus | Metabolic Syndrome | Impaired Glucose Tolerance | Gestational Diabetes Mellitus | Disorder of Glucose Regulation

United States
Peking University Third Hospital

Completed

Effect of Metformin on Patients With Polycystic Ovary Syndrome

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

China
University of Minnesota

Not yet recruiting

Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia

Oral Leukoplakia

United States
Fudan University

Recruiting

Metformin and Insulin to Pancreatic Cancer Related Diabetes (Type 3c)

Diabete Mellitus | Pancretic Cancer

China
Lille Catholic University
Centre Hospitalier Arras

Recruiting

Impact of Metformin on Leptin Transport in Cerebrospinal Fluid of Obese Patients (LEPTOB)

Obesity Without Type 2 Diabetes, With BMI>30

France
Bethesda Diabetes Research Center
University Medical Center Groningen; Maastricht University Medical Center; Medical... and other collaborators

Recruiting

Pregnancy Outcomes: Effects of Metformin Study (POEM Study) (POEM)

Insulin Resistance | Gestational Diabetes

Netherlands
Chang Gung Memorial Hospital

Unknown

Gut Microbiota and Bile Acids in Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2 | Metformin | YH1

Taiwan
GlaxoSmithKline

Completed

AVANDAMET Versus Metformin For Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Canada
Hospices Civils de Lyon

Unknown

Metformin Use in Chronic Kidney Disease: The CKD-Met Study (CKD-Met)

Type 2 Diabetes | Chronic Kidney Disease

France
Semnan University of Medical Sciences

Terminated

Metformine and CC Compared With Placebo and CC for Induction Ovulation in PCOS Patients With Insulin Resistant

Polycystic Ovary Syndrome | Hyperandrogenism
Johns Hopkins University
Baylor College of Medicine; National Heart, Lung, and Blood Institute (NHLBI); Temple University

Not yet recruiting

Metformin IN Asthma for Overweight and Obese Individuals (MINA)

Asthma | Overweight and Obesity | Asthma Chronic
Bristol-Myers Squibb

Completed

A Research Study to Assess the Mechanism By Which Glucovance, Metformin, and Glyburide Work To Control Glucose Levels In Patients With Type 2 Diabetes

Diabetes Mellitus, Non-Insulin-Dependent

United States
University of Jordan

Completed

Dosage Reduction and Acute Glycemic Complications in People With Type 2 Diabetes Who Fast During Ramadan

Diabetes Mellitus, Type 2

Jordan
Peking University

Unknown

Metformin in Combined With Cisplatin Plus Paclitaxel With Advanced Esophageal Squamous Cell Carcinoma (ECMTPneo) (ECMTPneo)

Esophageal Squamous Cell Carcinoma

China
M.D. Anderson Cancer Center

Terminated

An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin

Colorectal Carcinoma

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Retrospective Analysis for Patients With Metabolic Syndrome

Metabolic Syndrome

China
King Edward Medical University

Completed

Comparison of the Effects of Metformin and Pioglitazone on Liver Enzymes and Ultrasound Changes in Non-Diabetic Non-Alcoholic Fatty Liver

NAFLD

Pakistan
Zagazig University

Completed

Insulin Sensitizers Role in Control of PCOS Vicious Cycle.

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

Egypt
Solvay Pharmaceuticals

Completed

A Controlled-Study on the Effect of a Combination of Fenofibrate and Metformin on Weight Loss and Weight Loss-Maintenance, in Obese Patients.

Obesity

Finland
University of Arizona
National Cancer Institute (NCI)

Recruiting

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

Oral Leukoplakia | Erythroplakia

United States, Canada
National Cancer Institute (NCI)

Recruiting

Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer

Lung Carcinoma

United States, Canada
Qingfeng Pharmaceutical Group

Unknown

Adjunctive Therapy of Andrographolid Sulfonatein Community Acquired Pneumonia

Community Acquired Pneumonia

China

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