Search clinical trials for: Membrane Transport Modulators

Total 23353 results

Acorda Therapeutics

Completed

Open-Label Extension Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR in Patients With Multiple Sclerosis

Multiple Sclerosis

United States, Canada
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); T... and other collaborators

Completed

Lubiprostone, Colonic Motility and Sensation

Healthy

United States
Vertex Pharmaceuticals Incorporated

Completed

Drug-Drug Interaction Study of VX-809 and VX-770 in Healthy Subjects

Cystic Fibrosis

Netherlands
Assistance Publique - Hôpitaux de Paris

Terminated

Dose-Dependent Effect of Thiazide in Dent's Disease Hypercalciuria (DESY)

Nephrolithiasis | Dent's Disease

France
The Hospital for Sick Children

Unknown

Using Furosemide to Prevent Fluid Overload During Red Blood Cell Transfusion in Neonates

Lung Disease

Canada
University of Oulu

Recruiting

Botulinum Toxin Injection in the Treatment of Open Abdomen

Open Abdomen | Botulinum Toxin Injection

Finland
King Chulalongkorn Memorial Hospital

Recruiting

Furosemide Stress Test Predicting Early Graft Function in Kidney Transplantation (FOSTIK)

Kidney Transplant; Complications | Delayed Graft Function | Kidney Function

Thailand
Indiana University

Completed

Chlorthalidone in Chronic Kidney Disease (CLICK)

Hypertension | Renal Insufficiency, Chronic

United States
Columbia University

Completed

Lasix for the Prevention of De Novo Postpartum Hypertension (LAPP)

Hypertension | Hypertension, Pregnancy-Induced | Postpartum Preeclampsia | Postpartum Pregnancy-Induced Hypertension

United States
Milton S. Hershey Medical Center

Terminated

A Single Dose Pharmaco-Diagnostic for Peripheral Nerve Continuity After Trauma

Nerve Injury

United States
George Washington University

Completed

Protocol to Assess the Severity of Acute Kidney Injury (AKI)

Acute Kidney Failure

United States
Le Bonheur Children's Hospital

Completed

IV Lacosamide: The Safety of Intravenous Lacosamide

Epilepsy

United States
Albert Einstein Healthcare Network

Completed

Assessment of Gait After Dysport Treatment

Equinovarus; Acquired

United States
Washington University School of Medicine
Acorda Therapeutics

Completed

Ampyra for Optic Neuritis in Multiple Sclerosis

Multiple Sclerosis | Optic Neuritis

United States
Sucampo Pharma Americas, LLC
Sucampo Pharmaceuticals, Inc.

Completed

Opioid-induced Bowel Dysfunction Pivotal Assessment of Lubiprostone (OPAL)

Opioid-Induced Bowel Dysfunction

United States, Canada
Eisai Inc.

Terminated

Open-Label Extension Study of Rufinamide Given as Adjunctive Therapy in Patients With Refractory Partial Seizures

Refractory Partial Onset Seizures

United States
Oregon Health and Science University
Oregon Clinical and Translational Research Institute

Completed

A Translational Approach to Gitelman Syndrome

Gitelman Syndrome

United States
UCB Pharma

Completed

A Multicenter, Open-Label Study To Investigate The Safety And Pharmacokinetics Of Lacosamide In Children With Partial Seizures

Epilepsy

United States, Belgium, Mexico
Biotie Therapies Inc.
Syneos Health

Completed

Exploratory Study to Evaluate the Effect of SYN111 (Rufinamide) in Patients With Generalized Anxiety Disorder (GAD)

Generalized Anxiety Disorder

United States
UCB Pharma

Completed

To Determine Tolerability and Efficacy of Long-term Oral Lacosamide in Patients With Partial Seizures

Partial Epilepsies

United States, Poland, United Kingdom, Switzerland, Hungary, Germany, Sweden, Lithuania
UCB Pharma

Completed

Trial to Assess Lacosamide as the First add-on Anti-epileptic Drug Treatment in Patients With Partial-onset Seizures

Partial Epilepsies

United States, Austria, Bulgaria, Czechia, Denmark, Finland, France, Greece, Italy, Mexico, Romania, Russian Federation, Spain, Switzerland, Turkey
UCB BIOSCIENCES, Inc.

Completed

Safety of Intravenous Lacosamide Dose Followed by Twice Daily Oral Lacosamide in Subjects With Partial-onset Seizures

Partial Epilepsies | Partial Onset Seizures

United States
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-661 Alone and in Combination With Ivacaftor in Subjects Homozygous or Heterozygous to the F508del-Cystic Fibrosis Transmembrane Conductance Regulator(CFTR) Mutation

Cystic Fibrosis

United States, Canada, Germany, United Kingdom
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Outcome of Botulinum Toxin Treatment for Oromandibular Dystonia (rétroBODOM)

Dystonia; Orofacial
Beth Israel Deaconess Medical Center
National Institute of Nursing Research (NINR)

Completed

Aerosol Inhalation Treatment for Dyspnea

Healthy | Dyspnea

United States
Lawson Health Research Institute
UCB Pharma GmbH

Terminated

Lacosamide IV and EEG/EKG (LIVE) Study (LIVE)

Focal Epilepsy

Canada
Columbia University

Completed

Short and Long Term Treatment With 4-AP in Ambulatory SMA Patients

Spinal Muscular Atrophy

United States
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-809 Alone and in Combination With VX-770 in Cystic Fibrosis (CF) Patients Homozygous or Heterozygous for the F508del-CFTR Mutation

Cystic Fibrosis

United States, France, United Kingdom, Germany, Australia, New Zealand, Belgium
UCB Pharma

Completed

Post-Authorization Safety Study to Assess the Safety of Vimpat as add-on Therapy in Patients With Partial-onset Seizures (PASS)

Epilepsies, Partial

France, Germany, United Kingdom, Spain, Netherlands
Richard Barohn, MD

Completed

Effectiveness of Mexiletine for Treating People With Non-Dystrophic Myotonia

Non-Dystrophic Myotonia | Myotonia

United States, Canada, Italy, United Kingdom
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Mechanisms of Diuretic Resistance in Heart Failure, Aim 1 (MsDR)

Heart Failure

United States
Stanford University

Recruiting

Efficacy of Diuretics in Kidney Disease

End Stage Renal Disease | Chronic Kidney Disease

United States
Johannes Grand

Completed

Acute Effects of Furosemide on Hemodynamics and Pulmonary Congestion in Acute Decompensated Heart Failure.

Acute Heart Failure

Denmark
UCB Biopharma SRL

Active, not recruiting

A Study to Test the Long-term Use of Oral Lacosamide in Pediatric Study Participants Who Completed NCT01964560 (EP0034) or NCT00938912 (SP848) and Received Lacosamide Treatment

Epilepsy

Georgia, Hungary, Moldova, Republic of, Romania, Taiwan, Ukraine
Vertex Pharmaceuticals Incorporated

Completed

A Phase 2 Study to Evaluate Efficacy and Safety of VX-561 in Subjects Aged 18 Years and Older With Cystic Fibrosis

Cystic Fibrosis

United States, Belgium, Netherlands, Australia, Germany, Ireland, United Kingdom
Vertex Pharmaceuticals Incorporated

Terminated

A Pilot Study to Evaluate the Use of Smart Adherence Technology to Measure Lumacaftor/Ivacaftor Adherence in CF Subjects Homozygous for the F508del CFTR Mutation

Cystic Fibrosis

United States, Canada
Acorda Therapeutics

Completed

A Study to Evaluate the Efficacy and Safety of Two Dose Strengths of Dalfampridine Extended Release Tablets. (MILESTONE℠)

Post-Ischemic Stroke

United States, Canada
Vertex Pharmaceuticals Incorporated

Completed

Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansion

Cystic Fibrosis

United States
University College, London

Terminated

Bumetanide in Hypokalaemic Periodic Paralysis

Hypokalemic Periodic Paralysis

United Kingdom
UCB Pharma

Terminated

Trial to Assess Efficacy and Safety of Lacosamide in Subjects With Osteoarthritis of the Knee

Osteoarthritis

Poland, Germany, Romania, Hungary, United Kingdom, Sweden, Czechia
Bial - Portela C S.A.

Completed

Efficacy and Safety of Eslicarbazepine Acetate as Therapy for Patients With Post-Herpetic Neuralgia

Postherpetic Neuralgia
Jagiellonian University

Unknown

Effects of Denture-Related Stomatitis on Blood Pressure in Denture Wearers

Denture Stomatitis

Poland
Novartis

Completed

Aliskiren Plus HCTZ Compared to Aliskiren in Metabolic Syndrome Patients With Stage 2 Systolic Hypertension (AIMS)

Hypertension

United States
Boryung Pharmaceutical Co., Ltd

Completed

A Study to Evaluate the Safety and Pharmacokinetics After Oral Concurrent Administration of Fimasartan and Hydrochlorothiazide in Healthy Male Volunteers

Essential Hypertension
National Center for Research Resources (NCRR)
University of Tennessee

Completed

Phase III Randomized, Double-Blind, Placebo-Controlled Study of Mexiletine for Painful Diabetic Neuropathy

Pain | Diabetic Neuropathies | Paresthesia
University Hospital Tuebingen

Withdrawn

Dapagliflozin Effect on Erythropoiesis and Physical Fitness

Type 2 Diabetes Mellitus (T2DM)

Germany
Population Health Research Institute

Not yet recruiting

Single Dose Flecainide for Early Sinus Rhythm Conversion of Perioperative Atrial Fibrillation After Noncardiac Surgery (FLIP-AF)

Atrial Fibrillation | Surgery
UCB Pharma
SCHWARZ BIOSCIENCES GmbH - Part of UCB Group

Completed

A Trial to Assess the Efficacy and Safety of 400mg/Day Lacosamide in Subjects With Painful Diabetic Neuropathy

Painful Diabetic Neuropathy

Germany
UCB BIOSCIENCES, Inc.

Completed

Study to Investigate Safety and Tolerability of Intravenous Lacosamide in Children. (ASPIRE)

Epilepsy

United States, Hungary, Italy, Poland, Ukraine
UCB BIOSCIENCES, Inc.
UCB Biopharma SRL

Completed

A Clinical Study to Investigate the Efficacy and Safety of Lacosamide as an Add on Therapy in Children With Epilepsy With Partial-onset Seizures

Epilepsy

United States, Argentina, Australia, Belgium, Brazil, Bulgaria, China, Colombia, Croatia, Czechia, Estonia, France, Georgia, Greece, Hungary, Israel, Italy, Korea, Republic of, Latvia, Lithuania, Mexico, Moldova, Republic of, Monten... and more

Search clinical trials for: Membrane Transport Modulators

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