Search clinical trials for: Metformin+hydrochloride+prolonged+release

Total 576 results

Grünenthal GmbH

Completed

Tapentadol Prolonged Release (PR) Versus Oxycodone/Naloxone Prolonged Release in Severe Chronic Low Back Pain With a Neuropathic Component.

Back Pain | Low Back Pain | Neuropathic Pain

Germany, Spain, Austria, Italy
PegBio Co., Ltd.

Not yet recruiting

Study to Evaluate the Efficacy and Safety of PB-201 in Type 2 Diabetic Mellitus Patients With Poor Glycemic Control Via Metformin Hydrochloride Monotherapy

Type 2 Diabetes Mellitus

China
Mylan Pharmaceuticals Inc

Completed

Food BE Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage XR 500 mg

Healthy

United States
Takeda

Completed

Special Drug Use Surveillance of Pioglitazone/Metformin Hydrochloride Combination Tablets Survey on Long-term Use for Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus
Chinese Association of Geriatric Research

Completed

Efficacy of Metformin in Preventing Diabetes in China (ChinaDPP)

PreDiabetes

China
Janssen Research & Development, LLC

Completed

A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Co-administered With Canagliflozin in Healthy Fed and Fasted Participants

Healthy

United States
Shanghai Mental Health Center
Yantai University

Recruiting

Assessing Dopamine Transporter Occupancy in the Patients With Depression Brain With Toludesvenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET)

Major Depressive Disorder

China
Shanghai Mental Health Center
Yantai University

Completed

Assessing Dopamine Transporter Occupancy in the Healthy Adult Brain With Toludivenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET)

Major Depressive Disorder

China
Caio Eduardo Gonçalves Reis
University of Brasilia; Conselho Nacional de Desenvolvimento Científico e Tecnológico and other collaborators

Completed

Metabolic Effects of a Caloric Restriction High/Low Glycemic Index Diet Plus Metformin in Overweight/Obese Subjects

Obesity

Brazil
AstraZeneca

Completed

Bioequivalence Study of Fixed-dose Combinations and Coadministered Individual Tablets of Saxagliptin/Metformin-Brazil

Type 2 Diabetes Mellitus

Brazil
Shandong Suncadia Medicine Co., Ltd.

Completed

Study of the Bioequivalence and Food Effects of HRX0701 Tablets in Healthy Subjects

Type 2 Diabetes Mellitus

China
Merck KGaA, Darmstadt, Germany

Completed

Glucophage® Extended Release (XR) 750 Milligram (mg) Indonesia Bioequivalence (BE) Study

Healthy

Indonesia
H. Lundbeck A/S

Terminated

Efficacy and Safety of Lu AA34893 in Patients With Major Depressive Disorder

Major Depressive Disorder

Canada
Copenhagen University Hospital at Herlev

Not yet recruiting

Danish Precocious Puberty Study - DAPP Study A National Cohort Study on Incidence and Etiologies for Precocious Puberty (DAPP)

Puberty, Precocious

Denmark
Chipscreen Biosciences, Ltd.

Recruiting

Chiglitazar Added to Metformin for Type 2 Diabetes

Type 2 Diabetes

China
Mylan Pharmaceuticals Inc

Completed

Food Study Metformin Hydrochloride ER Tablets 750 mg and Glucophage XR 750 mg

Healthy

United States
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

GXR RM China BE Study (Darmstadt - Jiangsu)

Healthy

Germany
Texas Tech University Health Sciences Center, El...

Terminated

Glyburide vs Glucovance in the Treatment of GDM (GGIG)

Gestational Diabetes

United States
West Side Institute for Science and Education

Completed

Tolerance & Responsiveness Improvement for Metformin (TRIM)

Type2 Diabetes Mellitus

United States
Laboratorios Silanes S.A. de C.V.
Instituto Mexicano del Seguro Social

Completed

BIOAVAILABILITY OF Glimepiride/Extended Release Metformin (GLI/METXR): High Fat Diet Study (GLMT13)

Healthy

Mexico
University of Utah

Active, not recruiting

Role of Metformin on Muscle Health of Older Adults

Insulin Resistance | Muscle Atrophy

United States
Mylan Pharmaceuticals Inc

Completed

Food Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR 500 mg

Healthy

United States
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Completed

GXR RM (Glucophage® Extended Release Reduced Mass) 500 Milligram (mg) Korea Bioequivalence (BE) Study

Healthy

Korea, Republic of
Mylan Pharmaceuticals Inc

Completed

Fasting BE Study of Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR Tablets 500 mg

Healthy

United States
Biogen

Completed

Exploratory Study to Assess the Effect of Fampridine (BIIB041) on Walking Ability and Balance in Participants With Multiple Sclerosis. (MOBILE)

Multiple Sclerosis

Sweden, United Kingdom, Netherlands, Belgium, Canada, Italy
Donald Mabbott

Recruiting

Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour (Met Med Can)

Cognitive Impairment | Medulloblastoma, Childhood

Canada, Australia
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Metformin Hydrochloride ER Tablets 750 mg and Glucophage® XR Tablets 750 mg

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Non-fasting Conditions

Healthy

United States
Ain Shams University

Recruiting

Effect of Green Tea on Obese Pediatrics With Prediabetes

PreDiabetes

Egypt
Mylan Pharmaceuticals Inc

Completed

Fasting Study of Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR Tablets 500 mg

Healthy

United States
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Safety and Pharmacokinetics Study of CPL207280 Compound in Healthy Volunteers.

Healthy Volunteers

Poland
Sidney Kimmel Cancer Center at Thomas Jefferson...

Active, not recruiting

Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery

Larynx | Oral Cavity | LIP | Pharynx

United States
Sandoz

Completed

To Demonstrate the Relative Bioavailability of Metformin HCL 500 mg Extended Release (XR) Tablets Under Fasting Conditions

Type II Diabetes
AstraZeneca
Bristol-Myers Squibb

Completed

Study of Dapagliflozin in Combination With Metformin XR to Initiate the Treatment of Type 2 Diabetes

Type 2 Diabetes Mellitus

Korea, Republic of, United States, Mexico, India, Puerto Rico, Russian Federation
Al-Rasheed University College

Completed

Effects of Combined Metformin and Cabergoline in Comparison With Metformin Only Therapy on Ovarian and Hormonal Activities in Iraqi Patients With PCOS

Polycystic Ovary Syndrome

Iraq
University of California, Los Angeles

Not yet recruiting

Effect of Metformin, a Drug Used to Treat Diabetes, vs Placebo

Obesity | NIDDM

United States
Laboratorios Silanes S.A. de C.V.
Instituto Mexicano del Seguro Social

Completed

BIOAVAILABILITY OF GLI/METXR (4/850 mg) (GLMT12-SIL)

Healthy

Mexico
Aristotle University Of Thessaloniki

Completed

Clinical Trial of Crocus Kozanis Administration in Obese Children and Adolescents

Obesity | Dyslipidemias | PreDiabetes

Greece
Brigham and Women's Hospital
Arthritis Foundation

Recruiting

Preventing Injured Knees From osteoArthritis: Severity Outcomes (PIKASO)

Osteoarthritis, Knee | Post-traumatic Osteoarthritis | ACL Tear

United States
Peking University First Hospital

Recruiting

Semaglutide Improves Metabolic Abnormalities and Fertility in Obese Infertile Women With Polycystic Ovary Syndrome

Semaglutide | PCOS (Polycystic Ovary Syndrome)

China
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer

Larynx | Oral Cavity | Lip | Pharynx

United States
University of Guadalajara

Active, not recruiting

Effect of Berberine Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes

Impaired Glucose Tolerance | Prediabetes | Impaired Fasting Glucose

Mexico
Merck Sharp & Dohme LLC

Completed

Sitagliptin/Metformin Fed Bioequivalence Study (0431A-080)

Type 2 Diabetes Mellitus
Ferrer Internacional S.A.

Completed

Hypertension Study: Multinational Torasemide Trial in Mild to Moderate Hypertension.

Hypertension
Université Catholique de Louvain

Unknown

Practical Use of Advagraf de Novo After Kidney Transplantation According to Recipient Genetic Polymorphism (CYRANO)

Kidney Diseases

Belgium
A & U Tibbia College Karol Bagh

Completed

A Comparative Study of the Effect of Ayurvedic Drugs and Metformin in the Management of Diabetes Mellitus (Type II)

Diabetes Mellitus, Type 2

India
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Effect of Metformin as Add-on Therapy to Ibuprofen on Disease Activity in Knee Osteoarthritis Patients.

Knee Osteoarthritis | Metformin

Bangladesh
Astellas Pharma Europe Ltd.

Active, not recruiting

Study to Compare the Pharmacokinetics of Tacrolimus in Stable Pediatric Allograft Recipients Converted From Prograf® to Advagraf®

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Lung Transplantation | Intestine Transplantation

Belgium, Czechia, France, Germany, Italy, Poland, United Kingdom
Ambrilia Biopharma, Inc.

Completed

Efficacy and Safety of C2L-OCT-01 PR in Acromegalic Patients

Acromegaly

Belarus, Hungary, Romania, Serbia, Slovakia, Ukraine

3

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