Search clinical trials for: metformin HCl

Total 4849 results

British Columbia Cancer Agency
BC Cancer Foundation; Pancreatic Cancer Canada

Unknown

The Effects of Neoadjuvant Metformin on Tumour Cell Proliferation and Tumour Progression in Pancreatic Ductal Adenocarcinoma (Metformin 001)

Resectable Pancreatic Ductal Adenocarcinoma

Canada
Takeda

Terminated

Safety and Efficacy of TAK-559 in Combination With Metformin in Patients With Type 2 Diabetes Mellitus.

Diabetes Mellitus
Boehringer Ingelheim
Eli Lilly and Company

Completed

Relative Bioavailability of 2 Fixed Dose Combinations of Linagliptin/Metformin Compared With Single Tablets

Healthy

United States
Merck Sharp & Dohme LLC

Completed

A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Co-administration of Sitagliptin and Metformin as Individual Tablets (0431A-095)

Type 2 Diabetes
Laboratorios Silanes S.A. de C.V.

Recruiting

Oral Combination of Glimepiride/Vildagliptin/Metformin in Patients With T2D and Dual Treatment Failure

Type 2 Diabetes

Mexico
RenJi Hospital

Not yet recruiting

The Effect of Henagliflozin and Metformin on Myocardial Tissue-level Characteristics

Myocardial Fibrosis | Obesity | Type 2 Diabetes | Magnetic Resonance Imaging | Sodium-glucose Co-transporter-2 Inhibitor
Sun Yat-sen University

Not yet recruiting

The Effect of Metformin in Patients With Metastatic Castration-resistant Prostate Cancer

Metastatic Prostate Cancer

China
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Recruiting

Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma

Monoclonal Gammopathy of Undetermined Significance | Smoldering Multiple Myeloma

United States
Garvan Institute of Medical Research
National Health and Medical Research Council, Australia

Recruiting

Preventing Cognitive Decline With Metformin (MetMemory)

Cognitive Decline

Australia
National Cancer Institute (NCI)

Terminated

Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma

Renal Cell Carcinoma | Renal Cell Cancer | Hereditary Leiomyomatosis

United States
Cynthia Calkin
Stanley Medical Research Institute

Completed

Treating Insulin Resistance as a Strategy to Improve Outcome in Refractory Bipolar Disorder (TRIO-BD)

Bipolar Disorder

United States, Canada
University of Virginia

Completed

Effect of Metformin on Insulin Sensitivity and Pan-Arterial Vascular Function in Adults With Metabolic Syndrome (EJB044)

Metabolic Syndrome | Insulin Sensitivity

United States
Lars Christian Gormsen

Completed

Effects of Metformin on Hepatic FFA Metabolism

Type 2 Diabetes | Dyslipidemia
Virginia Commonwealth University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Pharmacogenetics of Metformin Action in PCOS

Polycystic Ovary Syndrome

United States
Novo Nordisk A/S

Completed

Comparison of the Blood Sugar Lowering Effect Between Repaglinide Plus Metformin and Repaglinide Alone in Type 2 Diabetics Not Previously Treated With Oral Sugar-lowering Drugs

Diabetes Mellitus, Type 2 | Diabetes

China
Novo Nordisk A/S

Completed

Efficacy and Safety of Repaglinide and Metformin Combination Therapy in Type 2 Diabetes Failing on Oral Anti-diabetic Drugs

Diabetes Mellitus, Type 2 | Diabetes

China
National Cancer Institute (NCI)

Completed

Metformin Hydrochloride in Preventing Esophageal Cancer in Patients With Barrett Esophagus

Esophageal Cancer | Barrett Esophagus

United States, Puerto Rico, Canada
Government Dental College and Research Institute...

Unknown

Locally Delivered 1% Metformin Gel in the Treatment of Intrabony Defects in Chronic Periodontitis

Intrabony Defects in Chronic Periodontitis

India
Odense University Hospital

Completed

The Effect of Metformin in Overweight Patients With Dysregulated Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Denmark
Zagazig University

Completed

Insulin Sensitizers Role in Control of PCOS Vicious Cycle.

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

Egypt
Solvay Pharmaceuticals

Completed

A Controlled-Study on the Effect of a Combination of Fenofibrate and Metformin on Weight Loss and Weight Loss-Maintenance, in Obese Patients.

Obesity

Finland
Boehringer Ingelheim
Eli Lilly and Company

Completed

Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Male and Female

Healthy

Germany
Chongqing Medical University

Completed

Comparison of Glargine and Oral Antidiabetic Drugs (OADs) in Newly Diagnosed Type 2 Diabetes

Diabetes

China
Daiichi Sankyo, Inc.

Completed

Phase 3 Study of Pexidartinib for Pigmented Villonodular Synovitis (PVNS) or Giant Cell Tumor of the Tendon Sheath (GCT-TS) (ENLIVEN)

Tenosynovial Giant Cell Tumor | Pigmented Villonodular Synovitis | Giant Cell Tumors of the Tendon Sheath

United States, France, Australia, Denmark, Spain, Netherlands, Germany, Canada, United Kingdom, Hungary, Italy, Poland
Aptose Biosciences Inc.

Completed

A Study of LOR-253 HCl in Patients With Advanced or Metastatic Solid Tumours

Advanced or Metastatic Solid Tumours

United States
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Clinical Study of Retagliptin Phosphate Combined With Metformin in the Treatment of Type 2 Diabetes

Type 2 Diabetes

China
Grupo Español de Investigación en Cáncer de Ovario
Neovii Biotech

Completed

Catumaxomab as a Consolidation Therapy in Patients With Ovarian Cancer in Second or Third Clinical Disease Remission

Ovarian Cancer

Spain
Photocure

Terminated

An Open Dose-finding Study of Oral Applied Hexaminolevulinate (HAL) Imaging in Patients With Suspicion or High Risk of Neoplasia in the Colon

Colon Cancer

Germany
Boehringer Ingelheim

Completed

Bioavailability of a Fixed Dose Combination Tablet With Empagliflozin (BI 10773) and Metformin Compared With the Monocomponents and Effect of Food on Bioavailability

Diabetes Mellitus, Type 2

Germany
Services Hospital, Lahore

Completed

Comparison of Hypoglycaemic Regimens During Ramadan Fasting in Type 2 Diabetes

Diabetes, Type 2

Pakistan
Sun Yat-sen University

Not yet recruiting

The Effect of Metformin in Patients With Newly Diagnosed mHSPC

Metastatic Prostate Cancer

China
University of Florida
ALS Association

Active, not recruiting

Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD

Frontotemporal Dementia | C9orf72 Amyotrophic Lateral Sclerosis (ALS)

United States
University of Pennsylvania
Pennsylvania Department of Health

Completed

Effects of Metformin During Nicotine Withdrawal (MEP)

Smoking | HIV-1-infection

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Stereotactic Radiosurgery and Metformin in Patients With Borderline-Resectable or Locally-Advanced Pancreatic Cancer

Acinar Cell Adenocarcinoma of the Pancreas | Duct Cell Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage I-III Pancreatic Cancer

United States
Tianjin Medical University Cancer Institute and...
Innovent Biologics (Suzhou) Co. Ltd.

Unknown

Sintilimab Combined With Metformin in First-Line Chemotherapy Refractory Advanced NSCLC Patients (SMART)

Non Small Cell Lung Cancer

China
Peking University

Unknown

Metformin in Combined With Cisplatin Plus Paclitaxel With Advanced Esophageal Squamous Cell Carcinoma (ECMTPneo) (ECMTPneo)

Esophageal Squamous Cell Carcinoma

China
University of Exeter
University of Bristol; University of Dundee

Withdrawn

Autoimmune Diabetes Accelerator Prevention Trial (adAPT)

Prediabetic State

United Kingdom
Poznan University of Medical Sciences
University of California, San Diego

Unknown

Androgen Responses to hCG and Ovarian Morphology in PCOS

PCOS

Poland
Novo Nordisk A/S

Completed

Comparison of Repaglinide and Metformin Administered Alone or in Combination in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

China
Novo Nordisk A/S

Completed

Comparison of Metformin, Repaglinide or the Combination of Both in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Spain
HaEmek Medical Center, Israel

Completed

A Comparison Between Two Oral Hypoglycemics - Metformin and Glybenclamide for the Treatment of Gestational Diabetes Mellitus

Gestational Diabetes Mellitus

Israel
M.D. Anderson Cancer Center

Terminated

An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin

Colorectal Carcinoma

United States
Eunice Kennedy Shriver National Institute of Child...
University of Pittsburgh; University of Washington; University of Texas; RTI International and other collaborators

Unknown

Glyburide and Metformin for Gestational Diabetes Mellitus (GDM) (GDM)

Gestational Diabetes Mellitus

United States
IlDong Pharmaceutical Co Ltd

Completed

A Open-label, Single-dose, 2-Sequence, 2-Period, Crossover Study to Assess Safety and Pharmacokinetics of a Nateglinide/Metformin HCl Combined Tablet Compared With a Nateglinide 120 mg Tablet and Metformin HCl 500 mg Tablet Under Fasting Conditions in Healthy Male Subjects

Healthy Volunteers

Korea, Republic of
GlaxoSmithKline

Completed

Drug Interactions From Simultaneous Administration Of Metformin And GSK189075 To Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Type 2 Diabetes Mellitus

Mexico
LG Life Sciences

Completed

Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of LC15-0444 and Metformin After Oral Administration in Healthy Male Subjects

Healthy

Korea, Republic of
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Metformin Hydrochloride in Treating Women With Stage I or Stage II Breast Cancer That Can Be Removed By Surgery

Breast Cancer

United States
University Health Network, Toronto

Active, not recruiting

The Metformin Active Surveillance Trial (MAST) Study (MAST)

Prostate Cancer

Canada
Ain Shams University

Completed

Effect of Metformin in Children With Type 1 Diabetes

Effect of Change in T1DM Glycemic Control

Egypt
Hospital Civil de Guadalajara

Unknown

Metformin and Systemic Inflammation in HIV (Metfo)

PreDiabetes | HIV-1-infection

Mexico

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