Search clinical trials for: Methotrexate, Hydroxychloroquine

Total 1907 results

Plan Nacional sobre el Sida (PNS)
Effice Servicios Para la Investigacion S.L.

Completed

Randomized Clinical Trial for the Prevention of SARS-CoV-2 Infection (COVID-19) in Healthcare Personnel (EPICOS)

Coronavirus Infection

Spain
National University Hospital, Singapore

Completed

A Preventive Treatment for Migrant Workers at High-risk of COVID-19

Covid-19

Singapore
Abramson Cancer Center of the University of Pennsylvania
National Cancer Institute (NCI)

Completed

Hydroxychloroquine and Temsirolimus in Treating Patients With Metastatic Solid Tumors That Have Not Responded to Treatment

Unspecified Adult Solid Tumor, Protocol Specific

United States
University of Medicine and Dentistry of New Jersey
National Cancer Institute (NCI)

Terminated

Hydroxychloroquine, Carboplatin, Paclitaxel, and Bevacizumab in Recurrent Advanced Non-Small Cell Lung Cancer

Lung Cancer

United States
National Institute of Diabetes and Digestive and...
Juvenile Diabetes Research Foundation

Terminated

Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes Mellitus (TN-22)

Type1 Diabetes Mellitus

United States, Australia, Italy, United Kingdom, Sweden, Canada
Instituto de Investigación Marqués de Valdecilla

Withdrawn

Randomized, Controlled, Double-blind Clinical Trial Comparing the Efficacy and Safety of Chemoprophylaxis With Hydroxychloroquine in Patients Under Biological Treatment and / or JAK Inhibitors in the Prevention of SARS-CoV-2 Infection

COVID 19 | Immunomediated Inflammatory Disease in Treatment With Biological Agents and / or Jak Inhibitors
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Rutgers Cancer Institute of New Jersey

Terminated

Hydroxychloroquine in Blocking Autophagy in Patients With Prostate Cancer Undergoing Surgery or Active Surveillance

Prostate Carcinoma

United States
Brigham and Women's Hospital
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Hydroxychloroquine to Improve Insulin Sensitivity in Rheumatoid Arthritis (RA PLUS)

Rheumatoid Arthritis | Insulin Resistance

United States
Merck Sharp & Dohme LLC
Integrated Therapeutics Group

Completed

Remicade Study in Psoriatic Arthritis Patients Of Methotrexate-Naïve Disease (RESPOND) (Study P04422)

Arthritis, Psoriatic
Assiut University

Not yet recruiting

Topical Methotrexate Microemulsion in the Treatment of Plaque Psoriasis

Psoriasis | Methotrexate
CHU de Reims

Completed

Kinetics of Elimination of Methotrexate and Its Major Metabolite 7-OH-methotrexate for Observant Patients (MetU)

Rheumatoid Arthritis

France
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Stem Cell Transplantation for Metastatic Solid Tumors

Neoplasm Metastasis

United States
Guy's and St Thomas' NHS Foundation Trust
Medical Research Council

Recruiting

Hydroxychloroquine in ANCA Vasculitis Evaluation (HAVEN)

Microscopic Polyangiitis | Churg-Strauss Syndrome | ANCA Associated Vasculitis | Wegener Granulomatosis

United Kingdom
Milton S. Hershey Medical Center
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Active, not recruiting

Study of Anti-Malarials in Incomplete Lupus Erythematosus (SMILE)

Systemic Lupus Erythematosus

United States
National Institute of Respiratory Diseases, Mexico

Completed

Hydroxychloroquine Chemoprophylaxis in Healthcare Personnel in Contact With COVID-19 Patients (PHYDRA Trial) (PHYDRA)

Severe Acute Respiratory Syndrome | COVID-19

Mexico
Nucleo De Pesquisa E Desenvolvimento De Medicamentos...

Unknown

Comparative Study of Hydroxychloroquine and Ivermectin in COVID-19 Prophylaxis

Coronavirus Infections

Brazil
Abderrahmane Mami Hospital
Dacima Consulting; Eshmoun Clinical Research Center

Withdrawn

Assessment of Efficacy and Safety of HCQ and Antibiotics Administrated to Patients COVID19(+) (COVID+PA)

Patients With COVID19

Tunisia
Intermountain Health Care, Inc.
University of Utah; Utah Department of Health

Unknown

Hydroxychloroquine vs. Azithromycin for Outpatients in Utah With COVID-19 (HyAzOUT)

COVID-19

United States
Medical Research Council
Wellcome Trust

Unknown

Evaluation of the Efficacy of Hydroxychloroquine in Decreasing Immune Activation in Asymptomatic HIV-infected Patients (HCQ-01)

HIV Infections
University of Manitoba
University of Nairobi

Completed

Inducing Immune Quiescence to Prevent HIV Infection in Women (IIQ)

HIV

Kenya
Zhejiang University

Recruiting

Ruxolitinib With Calcineurin and Methotrexate vs. Calcineurin Plus Methotrexate and Mycophenolate Mofetil as Graft Versus Host Disease Prophylaxis for HLA-haploidentical Hematopoietic Stem Cell Transplantation

Graft Versus Host Disease

China
UCB Pharma

Completed

A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis (C-early)

Rheumatoid Arthritis

Germany, United States, Argentina, Australia, Austria, Belgium, Canada, Colombia, Czechia, France, Hungary, Ireland, Italy, Mexico, Monaco, Netherlands, Poland, Romania, Spain, Sweden, Switzerland, United Kingdom
National Institute of Allergy and Infectious Diseases...
Autoimmunity Centers of Excellence

Terminated

Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis (StopRA)

Healthy Participants | Rheumatoid Arthritis (RA) Prevention

United States
Intermountain Health Care, Inc.
University of Utah

Completed

Hydroxychloroquine vs. Azithromycin for Hospitalized Patients With Suspected or Confirmed COVID-19 (HAHPS)

COVID-19

United States
AHS Cancer Control Alberta

Recruiting

Immune-Mediated Pathophysiology And Clinical Triage Program (IMPACT 2)

Arthritis | Arthralgia

Canada
University of New Mexico

Terminated

Non-comparative Trial of the Combination of HCQ and AZI in the Treatment of ICU Patients

COVID-19

United States
LCMC Health

Terminated

Treatment in Patients With Suspected or Confirmed COVID-19 With Early Moderate or Severe Disease (RCT)

COVID-19

United States
Centre Hospitalier Universitaire de Saint Etienne
Institut Pasteur

Terminated

Chemoprophylaxis of SARS-CoV-2 Infection (COVID-19) in Exposed Healthcare Workers (COVIDAXIS)

COVID-19

France
Sheba Medical Center

Unknown

Clinical Trial to Assess Safety and Efficacy of Combination Therapy: Hydroxychloroquine, Pegylated Interferon Alpha-2a and Ribavirin in Chronic Hepatitis C Subjects Non-responders to the Standard of Care Therapy.

Chronic Hepatitis C
Women's Hospital School Of Medicine Zhejiang University
Qilu Hospital of Shandong University; Huazhong University of Science and Technology and other collaborators

Recruiting

Combination of Methotrexate(MTX) and Actinomycin(ACTD) in the Low Risk Gestational Trophoblastic Neoplasma （GTN） Patients With Score of 5-6

Gestational Trophoblastic Tumor | Effects of Chemotherapy | Drug Toxicity

China
Vastra Gotaland Region
Göteborg University

Recruiting

Effects of Tofacitinib vs Methotrexate on Rheumatoid Arthritis Interstitial Lung Disease (PULMORA)

Rheumatoid Arthritis | ILD | Interstitial Lung Disease Due to Systemic Disease (Disorder) | RA

Sweden
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Testing Dabrafenib and Trametinib With or Without Hydroxychloroquine in Stage IIIC or IV BRAF V600E/K Melanoma

Locally Advanced Melanoma | Unresectable Melanoma | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Pathologic Stage IV Cutaneous Melanoma AJCC v8

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Hydroxychloroquine in Treating Patients With Newly Diagnosed Chronic Graft-Versus-Host Disease

Graft Versus Host Disease

United States, Canada, Australia, Switzerland, Puerto Rico, New Zealand
Children's Hospital of Fudan University

Not yet recruiting

Hydroxychloroquine in Children's Interstitial Lung Diseases With Genetic Causes

Interstitial Lung Disease | Surfactant Dysfunction

China
Oregon Health and Science University
OHSU Knight Cancer Institute

Withdrawn

Assessing Hydroxychloroquine in Patients With SARS-CoV-2 (COVID-19)

COVID-19 | SARS-CoV-2

United States
Istinye University

Unknown

Proflaxis Using Hydroxychloroquine Plus Vitamins-Zinc During COVID-19 Pandemia

Coronavirus Infection | Pneumonitis

Turkey
Assistance Publique - Hôpitaux de Paris

Suspended

Study of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients: Sarilumab, Azithromycin, Hydroxychloroquine Trial - CORIMUNO-19 - VIRO (CORIMUNO-VIRO)

SARS-CoV-2 Infection | COVID19

France
Gustave Roussy, Cancer Campus, Grand Paris

Unknown

Epidemiology of SARS-CoV-2 and Mortality to Covid19 Disease in French Cancer Patients (ONCOVID)

Cancer & COVID 19

France
Université Catholique de Louvain

Completed

A Comparison of Methotrexate Alone or Combined to Infliximab or to Pulse Methylprednisolone in Early Rheumatoid Arthritis: A Magnetic Resonance Imaging Study

Rheumatoid Arthritis

Belgium
Hospices Civils de Lyon

Not yet recruiting

Hydroxychloroquine as a Steroid-sparing Agent in Extrapulmonary Sarcoidosis (CAESAR)

Sarcoidosis, Pulmonary

France
Fundació Institut de Recerca de l'Hospital de la...
Instituto de Salud Carlos III

Recruiting

Clinical Trial of the Use of Tocilizumab for Treatment of SARS-CoV-2 Infection (COVID-19) (TOCOVID)

COVID-19

Spain
Baqiyatallah Medical Sciences University

Withdrawn

Efficacy and Safety of Mucoadhesive Sustained Release, Mucodentol, in Comparison With Hydroxychloroquine to Prevent COVID-19

COVID-19

Iran, Islamic Republic of
Helsinki University Central Hospital
Finnish Cultural Foundation; Orion Corporation, Orion Pharma; Finnish Foundation... and other collaborators

Completed

Hydroxychloroquine for the Prevention of Cardiovascular Events in Myocardial Infarction Patients - a Safety Pilot Trial (OXI)

Myocardial Infarction | Cardiovascular Diseases | Inflammation | Acute Coronary Syndrome | Hydroxychloroquine | Antirheumatic Agents

Finland
Università Politecnica delle Marche
Ospedale di Circolo e Fondazione Macchi, Varese; Azienda Ospedaliera Ospedali... and other collaborators

Unknown

TOFAcitinib Plus Hydroxycloroquine vs Hydroxycloroquine in Patients With COVID-19 Interstitial Pneumonia (TOFACoV-2)

COVID-19 | Pneumonitis, Interstitial
Instituto de Cardiologia do Rio Grande do Sul
Hospital de Clinicas de Porto Alegre

Unknown

Anti-Inflammatory Drug and Endothelial Function (HOLD)

Cardiovascular Diseases | Coronary Artery Disease | Atherosclerosis | Sleep Apnea | Endothelial Dysfunction

Brazil
Wageningen University

Completed

Mum Can I Have Vegetables Again? Development of Vegetable Preferences (VaVo)

Vegetable Intake After Weaning With Vegetables or Fruits | Fruit Intake After Weaning With Vegetables or Fruits

Netherlands
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Itacitinib for the Prevention of Graft Versus Host Disease in Patients Undergoing Donor Stem Cell Transplantation

Hematopoietic and Lymphoid Cell Neoplasm | Hematologic and Lymphocytic Disorder | Allogeneic Stem Cell Transplant Recipient

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Study to Assess Compliance With Long-Term Mercaptopurine Treatment in Young Patients With Acute Lymphoblastic Leukemia in Remission

Childhood Acute Lymphoblastic Leukemia in Remission

United States, Canada, Australia
VA Office of Research and Development

Not yet recruiting

Targeting Ischemia-Induced Autophagy Dependence in Hepatocellular Carcinoma (TAQE)

Hepatocellular Carcinoma

United States
Cancer Trials Ireland
Novartis

Recruiting

PaTcH Study: A Phase 2 Study of Trametinib and Hydroxychloroquine in Patients With Metastatic Refractory Pancreatic Cancer (PaTcH)

Pancreatic Cancer

Ireland

Search clinical trials for: Methotrexate, Hydroxychloroquine

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in El Salvador

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations