Search clinical trials for: Methylphenidate modified release

Total 7242 results

Pfizer
ViiV Healthcare

Completed

Study to Estimate the Pharmacokinetics, Bioavailability and Effect of Food on Single Dose Modified-release Lersivirine 500 mg in Healthy Subjects

Healthy Volunteer

Belgium
Heptares Therapeutics Limited
Quotient Clinical

Completed

Relative Bioavailability Study in Healthy Subjects to Evaluate the Pharmacokinetics of HTL0009936 After One Dose of Prototype Formulation

Alzheimer's Disease

United Kingdom
KalVista Pharmaceuticals, Ltd.

Completed

Phase 1 Crossover Study in Healthy Subjects to Evaluate the PK Profile of KVD824 Following Single and Multiple Doses of Modified Release (MR) Formulations

Hereditary Angioedema

United Kingdom
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Study of Modified Release Formulations of Danicopan in Healthy Adult Participants

Healthy

United Kingdom
GlaxoSmithKline
Quotient Clinical

Completed

A Study to Compare the Pharmacokinetics (PK) of GSK2982772 Following Administration of Different Modified Release (MR) Formulations in Capsule and MR Tablet Formulations Relative to an Immediate Release (IR) Tablet Formulation and to Check the PK of MR Formulation in Capsule Following Repeat Doses

Autoimmune Diseases

United Kingdom
GlaxoSmithKline
Quotient Sciences

Completed

A Study to Investigate the Pharmacokinetics (PK) of Modified Release (MR) Prototype Coated Tablet Formulations of GSK2982772

Autoimmune Diseases

United Kingdom
Amgen

Completed

Study to Evaluate Pharmacokinetics of Prototype Modified-Release Formulations Of Apremilast in Healthy Men

Healthy Volunteers

United States
Mahidol University

Not yet recruiting

The Study of Efficacy and Safety of Generic Methylphenidate Prolong-released Comparison With Original

Adhd
GlaxoSmithKline

Completed

A Study to Compare the Safety and Drug Levels in Blood When Using Various Forms of GSK189075 Given to Healthy Subjects

Diabetes Mellitus, Type 2 | Type 2 Diabetes Mellitus

United States
GlaxoSmithKline

Completed

First-Time-in-Humans Study to Assess Safety, Pharmacokinetics & Pharmacodynamics of SB756050

Diabetes Mellitus, Type 2

United States
Genzyme, a Sanofi Company

Completed

Study Comparing Thyrogen Versus a Modified Release of Recombinant Human Thyroid Stimulating Hormone

Healthy

United States
The University of Texas at San Antonio
The University of Texas Health Science Center at San Antonio

Unknown

FE-SaLiR: Function Improvement Exercise

Cognitive Impairment | Disability Physical

United States
Pfizer

Completed

A Phase 1 Study To Evaluate The Pharmacokinetics And Safety Of Three Modified Release And One Immediate Release Formulations Of Tofacitinib (CP-690,550) In Healthy Volunteers

Healthy

Singapore
London School of Hygiene and Tropical Medicine
University of Cambridge; University of Liverpool

Completed

TUNE! Teaching the UK About Noise Exposure: A Pilot Study (gildeaf1)

Noise-induced Hearing Loss and Tinnitus

United Kingdom
The University of Texas Health Science Center,...
National Institute of Mental Health (NIMH)

Completed

Methylphenidate for Attention Deficit Hyperactivity Disorder and Autism in Children

Autism | Attention Deficit Disorder With Hyperactivity

United States
Mansoura University

Unknown

Evaluation of Posterior Component Separation Modified TAR Technique "Transversus Abdominids Release" in the Treatment of Parastomal Hernia

TAR Technique

Egypt
Medical University of Vienna

Unknown

Methylphenidate as Treatment Option of Fatigue in Multiple Sclerosis (MS)

Multiple Sclerosis | Fatigue

Austria
UNION therapeutics

Active, not recruiting

Study to Assess the Efficacy and Safety of Orismilast in Atopic Dermatitis (ADESOS)

Skin Diseases | Atopic Dermatitis

Poland, United States, Hungary, Germany
Novartis Pharmaceuticals

Completed

Open-label Extension Evaluating Methylphenidate Hydrochloride Extended Release in Adults With Attention Deficit/Hyperactivity Disorder

Attention Deficit/Hyperactivity Disorder

Germany, United States, Belgium, Colombia, Denmark, Sweden
Janssen-Cilag International NV

Completed

A Study to Evaluate Effectiveness and Safety of Prolonged Release OROS Methylphenidate in Adults With Attention Deficit Hyperactivity Disorder

Attention Deficit/ Hyperactivity Disorder

France, Belgium, Germany, Spain, Switzerland, Denmark, Finland, Netherlands, Norway, Sweden, United Kingdom
UNION therapeutics

Completed

Study to Assess the Efficacy and Safety of Orismilast in Psoriasis (IASOS)

Skin Diseases | Psoriasis

United Kingdom, Poland, United States, Germany
Lung Biotechnology PBC

Completed

Extension of BPS-MR-PAH-203 in Pulmonary Arterial Hypertension (PAH) Patients

Pulmonary Arterial Hypertension

United States, Belgium, Czechia, Germany, Ireland, Romania
Prof. Huss

Terminated

Adherence to Stimulant Treatment in Attention-Deficit Hyperactivity Disorder (ADHD) Patients (ASTA) (ASTA)

ADHD

Germany
GlaxoSmithKline

Completed

Healthy Volunteer Study Using 3 Different Formulations of Firategrast

Multiple Sclerosis, Relapsing-Remitting

Australia
Lung Biotechnology PBC

Completed

An Open-Label Extension of BPS-MR-PAH-201 in Pulmonary Arterial Hypertension (PAH) Patients

Pulmonary Arterial Hypertension

United States, Belgium, Ireland
Eye & ENT Hospital of Fudan University

Unknown

The Clinical Effects of Modified TRS Treatment

Tinnitus, Subjective

China
Noorik Biopharmaceuticals AG

Terminated

A Study Evaluating the Utility of Ambrisentan in Lowering Portal Pressure in Patients With Liver Cirrhosis

Cirrhosis | Ascites | Portal Hypertension

Spain
Rock Creek Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and Pharmacokinetics of Modified and Immediate Release Anatabine Citrate Formulations

Pharmacokinetics of Anatabine

United Kingdom
Boston Children's Hospital
National Institute of Mental Health (NIMH)

Completed

Methylphenidate for Treating Attention Deficit Hyperactivity Disorder in Children With Both ADHD and Epilepsy

Epilepsy | Attention Deficit Disorder With Hyperactivity

United States
Massachusetts General Hospital

Completed

Methylphenidate ER Liquid Formulation in Adults With ASD and ADHD

Autism Spectrum Disorder | Attention-deficit/Hyperactivity Disorder

United States
Icahn School of Medicine at Mount Sinai
U.S. Department of Education

Completed

Effectiveness of Controlled-Release Morphine for Chronic Neuropathic Pain After Spinal Cord Injury

Neuropathic Pain | Spinal Cord Injury

United States
Milton S. Hershey Medical Center
Children's Miracle Network

Terminated

Effects of Evening Dose of Immediate Release Methylphenidate on Sleep in Children With ADHD

Behavioral Insomnia of Childhood | Attention Deficit Disorder With Hyperactivity

United States
Massachusetts General Hospital
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

An Open Label Phase I/II Study of Dopamine Transporter Receptor Occupancy With OROS and Immediate Release Methylphenidate as Measured With C-11 Altropane in Human Subjects

Healthy Volunteers

United States
NYU Langone Health

Completed

Water Oxygenation and Brain Activity

Muscle Damage

United States
Asan Medical Center

Completed

The Treatment of Posterior Semicircular Canal Benign Paroxysmal Positional Vertigo (BPPV)

Benign Paroxysmal Positional Vertigo

Korea, Republic of
Children's Hospital of Philadelphia
Ortho-McNeil Janssen Scientific Affairs, LLC

Completed

Study of the Effects of Osmotic-Release Oral System (OROS) Methylphenidate (Concerta) on Attention and Memory (CHOP)

Attention Deficit Hyperactivity Disorder

United States
Boehringer Ingelheim

Completed

Headache Study to Compare Aggrenox Full Dose and Reduced Dose

Cerebrovascular Accident

Taiwan
Mayo Clinic
Ortho-McNeil Janssen Scientific Affairs, LLC

Completed

Testing Methylphenidate for Smoking Abstinence

Smoking

United States
Purdue Pharma LP

Terminated

Real-World Evidence of Duration of Effect of Adhansia XR (Extended-Release) for Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) (RE-DAX)

Attention-Deficit/Hyperactivity Disorder

United States
China Medical University Hospital

Completed

Evaluation of the Erector Spinae Muscle in Different Position and the Change After Receiving Myofascial Release.

Low Back Pain

Taiwan
Astellas Pharma Inc
Astellas Pharma Korea, Inc.

Completed

Pharmacokinetics of Tacrolimus in Liver Transplantation Patients Treated With Prograf and Modified Release Tacrolimus

Liver Transplantation

Korea, Republic of
Lung Biotechnology PBC

Completed

Dose-response Study of the Safety and Efficacy of Beraprost Sodium Modified Release (BPS-MR) in Patients With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

United States, Belgium, Czechia, Germany, Ireland, Romania
Diurnal Limited

Completed

Chronocort Versus Plenadren Replacement Therapy in Adults With Adrenal Insufficiency (CHAMPAIN)

Primary Adrenal Insufficiency

Germany, United Kingdom
Lung Biotechnology PBC

Completed

A Multi-Center, Open-Label, Multiple Dose, Dose Finding Study Exploring the Safety and Tolerability of Beraprost Sodium Modified Release in PAH Patients

Pulmonary Arterial Hypertension

United States, Ireland, Belgium
Massachusetts General Hospital
Ortho-McNeil Janssen Scientific Affairs, LLC

Completed

A Study of Repeat Dosing of OROS® Methylphenidate Hydrochloride (CONCERTA®) and Immediate Release Methylphenidate Hydrochloride in Healthy Adults

Healthy

United States
Massachusetts General Hospital
ElMindA Ltd

Completed

Diagnostic Utility of Attention Deficit Hyperactivity Disorder (ADHD) by Brain Activity Flow Patterns Analysis Using Evoked Response Potentials

Attention Deficit Hyperactivity Disorder

United States
The Adelaide and Meath Hospital, incorporating...

Unknown

Optimising Steroid Replacement in Patients With Adrenal Insufficiency

Adrenal Insufficiency

Ireland
UCB Pharma

Completed

The COMACS Study: A Comparison of Methylphenidates in an Analog Classroom Setting

Attention Deficit Hyperactivity Disorder
University of Cincinnati
National Institute on Drug Abuse (NIDA); Ortho-McNeil Janssen Scientific Affairs...

Completed

Smoking Cessation for Adults With Attention Deficit Hyperactivity Disorder (ADHD)

Smoking | ADHD

United States
Pfizer

Completed

Clinical Study to Evaluate Blood Concentrations of PF-06700841 After Oral Dose as Different Formulations

Healthy Participants

Belgium

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