Search clinical trials for: Multiple ascending dose of X842

Total 4622 results

Emerald Health Pharmaceuticals

Completed

To Evaluate the Safety and Tolerability, Pharmacokinetics, Food-effect and Pharmacodynamics of EHP-101 in Healthy Volunteers

Healthy

Australia
iOnctura

Completed

A Study to Assess an ATX Inhibitor (IOA-289) in Healthy Volunteers

Healthy

Italy
GlaxoSmithKline

Completed

A Study in Healthy Volunteers of Single Doses of Orally Administered Investigational Product to Investigate Safety, Tolerability, and Pharmacokinecs.

Dyslipidaemias

United States
Arthrosi Therapeutics
Iqvia Pty Ltd

Completed

Pharmacokinetic Study of AR882 in Subjects With Various Degrees of Renal Impairment

Renal Impairment

United States, New Zealand
Longbio Pharma

Active, not recruiting

A Study of Single and Multiple Doses of LP-003 in Healthy Adult Participants

Chronic Spontaneous Urticaria

China
Longbio Pharma

Recruiting

A Study of Single and Multiple Doses of LP-005 in Healthy Adult Participants

Paroxysmal Nocturnal Hemoglobinuria (PNH)

China
Menarini Group

Completed

Oral Treatment for Orthopaedic Post-operative Pain With Dexketoprofen Trometamol and Tramadol Hydrochloride (DAVID-art)

Acute Pain

Serbia, Latvia, Spain, Hungary, Lithuania, Poland, Taiwan, Czech Republic, Germany, Ukraine
Kind Pharmaceuticals LLC

Completed

A Dose-escalation Study of AND017 in Healthy Subjects

Healthy Volunteers

Australia
Curacle Co., Ltd.
KCRN Research, LLC

Completed

First-In-Human Study of CU06-1004 Following Single and Multiple Ascending Doses in Healthy Volunteers

Diabetic Macular Edema

United States
Menarini Group

Completed

Oral Treatment for Gynaecological Post-operative Pain With Dexketoprofen Trometamol and Tramadol Hydrochloride (DAVID lap)

Acute Pain

Romania, Poland, Hungary, Latvia, Lithuania, Russian Federation, Slovakia, Spain
Samsung Medical Center

Completed

Accuracy of Pre-existing Risk Scoring Models for Predicting Acute Kidney Injury in Patients Who Underwent Aortic Surgery Using a Gray Zone Approach

Aortic Surgery | Postoperative Acute Kidney Injury

Korea, Republic of
Waterstone Pharmaceutical (Wuhan) Co., LTD.

Completed

The Safety and Tolerability of WS016 in Healthy Chinese Volunteers

Hyperkalemia

China
Galapagos NV

Completed

A Study to Assess Safety, Tolerability and Pharmacokinetics of GLPG2737 in Healthy Subjects

Healthy

Netherlands
Asian Institute of Gastroenterology, India

Unknown

Single-Versus Multiple-dose Antimicrobial Prophylaxis for Peroral Endoscopic Myotomy in Achalasia (SMAPP)

Achalasia Cardia

India
GangaGen, Inc.

Completed

Safety & Efficacy of an Antibacterial Protein Molecule Applied Topically to the Nostrils of Volunteers and Patients

Bacterial Infections | Infectious Disease

Singapore
Praxis Precision Medicines

Active, not recruiting

A Clinical Trial of PRAX-222 in Pediatric Participants With Early Onset SCN2A Developmental and Epileptic Encephalopathy

Epilepsy | SCN2A-DEE

United States
Daewoong Bio Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of rhEGF Eye Drops in Healthy Male Subjects

Dry Eye Syndromes

Korea, Republic of
Longbio Pharma

Active, not recruiting

A Study of Single and Multiple Dose Administration of LP-001 in Healthy Subjects

Myelodysplastic Syndrome (MDS)

China
Ablynx

Completed

Caplacizumab Single and Multiple Dose Study in Healthy Japanese and White Subjects.

Healthy Volunteers

United States
A.Menarini Asia-Pacific Holdings Pte Ltd

Unknown

Different Level of Single-dose and Multiple-dose Bilastine PK Study in Chinese Population

Pharmacokinetics

China
Enterome
Covance

Active, not recruiting

First-in-Human, Phase 1b/2a Trial of a Multipeptide Therapeutic Vaccine in Patients With Progressive Glioblastoma (ROSALIE)

Glioblastoma, Adult

United States, Spain, France, Germany
Newsoara Biopharma Co., Ltd.

Recruiting

Safety, Tolerance and Pharmacokinetics of THR-1442 in Chinese Healthy Subjects

T2DM (Type 2 Diabetes Mellitus)

China
Cinclus Pharma AG
Parexel

Completed

A Study in Patients With Erosive Esophagitis to Investigate Safety, Tolerability, and Healing Rates After 4 Weeks Treatment of X842 or Lansoprazole and Symptom Pattern During Subsequent 4 Weeks Treatment With Lansoprazole

Erosive Esophagitis

Poland, Bulgaria, Serbia, Georgia, United States, Czechia, Hungary, Ukraine
Recida Therapeutics, Inc.

Terminated

Single and Multiple Dose Escalation Trial of an Intravenous Antibiotic RC-01

Safety

United States
Nutrition Institute, Slovenia
MEDEDUS, Ljubljana, Slovenia; Vizera d.o.o.; Valens Int. d.o.o., Slovenija

Completed

Bioavailability Study of CoQ10 Formulations in Healthy Elderly Adults (CoQ10-01)

Bioavailability of Coenzyme Q10

Slovenia
Knopp Biosciences
Biogen

Completed

Dexpramipexole Japanese PK Study

Amyotrophic Lateral Sclerosis

United Kingdom
Jiangsu Sinorda Biomedicine Co., Ltd

Unknown

Study to Evaluate the Safety and Efficacy of X842 in Patients With Reflux Esophagitis

Reflux Esophagitis

China
Chong Kun Dang Pharmaceutical

Completed

Evaluation of the Safety and Tolerability of CKD-510 in Healthy Subjects

Healthy Volunteers

France
Chong Kun Dang Pharmaceutical

Completed

The Parallel Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of CKD-843 A

Alopecia

Korea, Republic of
GlaxoSmithKline

Completed

To Evaluate Plasma and Pulmonary Pharmacokinetics of GSK2140944

Infections, Bacterial

United States
Regeneron Pharmaceuticals

Active, not recruiting

Study to Investigate the Safety and Tolerability of Odronextamab in Patients With CD20+ B-Cell Malignancies (ELM-1)

Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma

United States, United Kingdom, Israel, Germany, France
Guohua Zeng

Unknown

Comparison of Multiple-, Single- and Zero-dose of Ciprofloxacin Prophylaxis in Retrograde Intrarenal Surgery (RIRS)

Kidney Stones

China
Boehringer Ingelheim

Completed

Safety, Pharmacokinetics, and Pharmacodynamics of BIRT 2584 XX Administered as Multiple Doses and Safety and Pharmacokinetics of BIRT 2584 XX Administered With and Without Food as Single Dose to Healthy Male Volunteers

Healthy
LG Chem

Completed

An Ascending Dose, Single/Multiple Dosing, Food Effect Clinical Trial to Evaluate Pharmacokinetics, Safety and Tolerability in Healthy Subjects After Oral Administration of Gemigliptin (Phase I)

Type 2 Diabetes Mellitus

China
Asana BioSciences

Completed

A Study of ASN007 in Patients With Advanced Solid Tumors

Cancer | Neoplasm Metastasis | Pancreatic Cancer | Metastatic Cancer | Metastatic Lung Cancer | Pancreas Adenocarcinoma | Metastatic Melanoma | Colon Cancer | Colonic Neoplasms | Pancreas Cancer | Non Small Cell Lung Cancer Metastatic | Neoplasm | Pancreas Neoplasm | Metastatic Pancreatic Cancer | Metastatic Colon Cancer and other conditions

United States
Radboud University Medical Center

Completed

the Influence of Remote Ischemic Preconditioning on Inflammation During Human Endotoxemia (RISPENDO)

Autoimmune Diseases | Infection

Netherlands
Tianjin Chasesun Pharmaceutical Co., LTD
Southwest Hospital, China

Completed

Study of Multiple-dose Kukoamine B Mesilate in Healthy Volunteers

Healthy

China
Amplia Therapeutics Limited

Recruiting

ACCENT: AMP945 in Combination With Nab-paclitaxel and Gemcitabine for Treatment of Pancreatic Cancer

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma | PDAC

Australia, Korea, Republic of
Sheba Medical Center

Unknown

Neurodevelopmental Outcomes of Preterm Infants Treated for Pain Management With Repeated Doses of Sucrose 24%

Development

Israel
PHARMENTERPRISES LLC

Completed

Double-blind, Randomized, Placebo-controlled Study of the Safety, Tolerability and Pharmacokinetics of Ascending Doses of XC243 After Single and Multiple Oral Administration in Healthy Volunteers.

Healthy Volunteers

Russian Federation
Daewoong Pharmaceutical Co. LTD.

Completed

Pharmacokinetic Interaction Between DWP14012 and DWC202005 in Healthy Volunteers

Drug-drug Interaction

Australia
ImmuneMed, Inc.

Completed

Safety, Tolerability, Pharmacokinetics of hzVSf-v13 in Healthy Adults (Intravenous and Subcutaneous Administration)

Healthy Volunteers

Australia
Asan Medical Center
JW Pharmaceutical

Completed

Drug Interaction and Safety Between Pitavastatin and Valsartan (CWP-PTV-101)

Healthy

Korea, Republic of
Cellectar Biosciences, Inc.

Recruiting

Study of Iopofosine I 131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) and Pivotal Expansion in Waldenstrom Macroglobulinemia (CLOVER-WaM)

Multiple Myeloma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Diffuse Large B Cell Lymphoma | Small Lymphocytic Lymphoma | Central Nervous System Lymphoma

United States, Australia, Czechia, Greece, Israel, Brazil, Finland, France, Spain, Turkey, United Kingdom
Asana BioSciences

Terminated

Study of ASN003 in Subjects With Advanced Solid Tumors

Melanoma | Neoplasms | Colorectal Neoplasm | Carcinoma, Non-small Cell Lung

United States
Institute for Clinical and Experimental Medicine

Recruiting

INSULIN THERAPY DE-INTENSIFICATION WITH iGlarLixi (IDEAL)

Type 2 Diabetes Treated With Insulin

Czechia
Estetra

Completed

Safety, Tolerability and Pharmacokinetics of Estetrol (E4) After Single and Multiple Oral Doses in Healthy Female Volunteers

Menopause | Contraception

Bulgaria
Human Genome Sciences Inc.
GlaxoSmithKline

Completed

Study of Belimumab Administered Subcutaneously to Healthy Subjects

Healthy

United States
Georgia State University

Recruiting

Biphasic Effects of Acute Alcohol Intoxication on Bystander Intervention

Alcohol Intoxication

United States
MicuRx
Worldwide Clinical Trials

Completed

Single Dose and Multiple Dose Escalation Trial of an Oral Formulation of MRX-4

Safety

3

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