Search clinical trials for: Nalmefene hydrochloride

Total 7358 results

University of New Mexico

Not yet recruiting

Nalmefene vs Naloxone for the Treatment of Recurrent Respiratory Depression After Opioid Overdose

Opioid Overdose | Opiate Overdose

United States
Opiant Pharmaceuticals Inc

Completed

Pharmacodynamic Evaluation of Intranasal Nalmefene

Pharmacodynamic

United States
Purdue Pharma LP

Withdrawn

Clinical Outcomes From Nalmefene (COINED)

Opioid Overdose
Otsuka Pharmaceutical Co., Ltd.
H. Lundbeck A/S

Completed

A Single-center, Open-label, Single-dose Study Investigating the Safety, Tolerability, and Pharmacokinetic Properties of Nalmefene 10 mg Tablets in Healthy Japanese Male Subjects

Alcohol Dependence

Japan
Opiant Pharmaceuticals Inc

Completed

Pharmacokinetic Evaluation of Intranasal Nalmefene Using Three Dosing Regimens

Opioid Overdose

United States
Opiant Pharmaceuticals Inc

Completed

Pharmacokinetic Evaluation of Intranasal Nalmefene

Pharmacokinetics

United States
Otsuka Pharmaceutical Co., Ltd.
H. Lundbeck A/S

Completed

A Long-term Extension Study for the Phase 3 Study of Nalmefene (339-14-001) in Patients With Alcohol Dependence

Alcohol Dependence

Japan
Otsuka Pharmaceutical Co., Ltd.

Active, not recruiting

Post-Marketing Surveillance Study of Nalmefene Hydrochloride Hydrate in Patients With Alcohol Dependence

Alcohol Dependence

Japan
Otsuka Pharmaceutical Co., Ltd.
H. Lundbeck A/S

Completed

A Multicenter, Randomized, Double-blind, Placebo-controlled, 3-parallel-group Comparison Trial to Investigate the Effect of Nalmefene on Alcohol Consumption Reduction in Patients With Alcohol Dependence (Phase 3 Trial)

Alcohol Dependence

Japan
Somaxon Pharmaceuticals

Completed

Nalmefene Gambling Study: Study of Nalmefene HCl in the Treatment of Pathological Gambling

Pathological Gambling
H. Lundbeck A/S

Completed

Effects of Nalmefene After Single Dose on the Blood Oxygen Level Dependent (BOLD) fMRI Signal in the Ventral Striatum to Reward Responding in the Monetary Incentive Delay Task (MIDT), in Non-treatment Seeking Subjects With Alcohol Dependence Following Alcohol Challenge

Alcohol Dependence

United Kingdom
Somaxon Pharmaceuticals

Completed

Nalmefene Smoking Cessation Study

Smoking Cessation

United States
H. Lundbeck A/S

Completed

Pharmacokinetic Properties of Nalmefene in Subjects With Renal Impairment and in Healthy Subjects

Renal Impairment

Germany
H. Lundbeck A/S

Completed

Treatment of Patients Suffering of Alcohol Dependence and Impaired Liver Function With Selincro® As-needed Use

Alcohol Dependence

Germany
Centre Hospitalier Universitaire, Amiens

Withdrawn

Nalmefene in Patients With Alcoholic Compensated Cirrhosis for the Treatment of Alcohol Dependence. (NalmeCir)

Alcohol Dependence | Cirrhosis | Nalmefene

France
United BioPharma
Kaohsiung Medical University Chung-Ho Memorial Hospital; Taipei Veterans General... and other collaborators

Completed

To Investigate the Safety and Efficacy of UB-421 Monotherapy in HIV Infected Adults

HIV-1 Infection

Taiwan
H. Lundbeck A/S

Terminated

Study of 18 mg Selincro® As-needed Use, in the Treatment of Patients With Alcohol Dependence in Primary Care

Alcohol Dependence

France, Germany, Spain, United Kingdom
National Institute on Drug Abuse (NIDA)

Completed

Pharmacokinetic Evaluation of Nalmefene Administered Intranasally to Healthy Volunteers

Opioid-Related Disorders

United States
National Jewish Health

Completed

FiteBac Hand Sanitizer in the Management of Hand Dermatitis in Adults (FiteBac)

Hand Dermatitis

United States
Tharimmune Inc

Active, not recruiting

An Evaluation of The Absolute Bioavailability of TH104

Healthy

United States
University Hospital, Clermont-Ferrand

Unknown

Evaluation of Nalmefene in Impulse Control Disorders in Parkinson's Disease: A Prospective Open Label Study (Nalmefene TCI)

Parkinson Disease | Impulse Control Disorders

France
Nantes University Hospital

Recruiting

NAlmefene Versus Placebo in Addition to Treatment as Usual on Craving in Behavioural Addictions (NABAb)

Behavioural Addiction

France
RenJi Hospital
Shanghai Tong Ren Hospital; The First Affiliated Hospital of Zhengzhou University and other collaborators

Recruiting

Effect of Nalmefene on the Quality of Resuscitation in Patients Under General Anesthesia

Resuscitation

China
City of Hope Medical Center
National Cancer Institute (NCI)

Suspended

Copanlisib and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma

Recurrent Mantle Cell Lymphoma | Refractory Mantle Cell Lymphoma

United States
National Institute on Alcohol Abuse and Alcoholism...

Completed

Title: Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene Variation

AUD

United States
Central Institute of Mental Health, Mannheim
Lundbeck GmbH, Ericusspitze 2, 20457 Hamburg

Terminated

Single-dose of Nalmefene to Modulate Neural Alcohol Cue Reactivity (NALCUE)

Alcoholism

Germany
H. Lundbeck A/S

Completed

Efficacy of Nalmefene in Patients With Alcohol Dependence (ESENSE2)

Alcohol Dependence

Poland, Belgium, Czech Republic, France, Italy, Portugal, Spain
Fundació Institut de Recerca de l'Hospital de la...
Hospital Universitari General de Catalunya

Unknown

Nalmefene in Alcohol Dependence and Borderline Personality Disorder

Borderline Personality Disorder | Alcohol Use Disorder

Spain
H. Lundbeck A/S

Completed

Safety and Efficacy of Nalmefene in Patients With Alcohol Dependence (SENSE)

Alcohol Dependence

Poland, Russian Federation, Ukraine, Czech Republic, Estonia, Hungary, Latvia, Lithuania, Slovakia, United Kingdom
H. Lundbeck A/S

Completed

Efficacy of Nalmefene in Patients With Alcohol Dependence (ESENSE1)

Alcohol Dependence

Austria, Finland, Germany, Sweden
University of Bordeaux
Lundbeck France

Completed

Use of Selincro and Impact on Usual Practice (USE-PACT)

Alcohol Dependence

France
Yale University
First Pavlov State Medical University in St. Petersburg, Russia

Completed

Patient Driven Recovery With Nalmefene and Coaching

Opioid-use Disorder | Harmful; Use, Alcohol

United States
Neelesh Sharma MD PhD

Completed

Erlotinib Hydrochloride and Quinacrine Dihydrochloride in Stage IIIB-IV Non-Small Cell Lung Cancer

Stage IIIB Non-small Cell Lung Cancer | Recurrent Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer

United States
Xijing Hospital of Digestive Diseases

Completed

Primary Chemoprevention of Familial Adenomatous Polyposis With Berberine Hydrochloride

Colorectal Adenomas

China
Boston Medical Center
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Nalmefene (PETER PAIN)

HIV Infection | Pain | Alcohol Use

Russian Federation
Shenyang Sunshine Pharmaceutical Co., LTD.

Unknown

A Multi-site Bridging Study of Nalfurafine Hydrochloride Orally Disintegrating Tablet

Uremic Pruritus

China
Xijing Hospital of Digestive Diseases

Completed

A Research of Berberine Hydrochloride to Prevent Colorectal Adenomas in Patients With Previous Colorectal Cancer

Colorectal Adenomas

China
Galderma R&D

Completed

Metvix PDT in Participant With "High Risk" Basal Cell Carcinoma

Basal Cell Carcinoma

Australia
M.D. Anderson Cancer Center

Withdrawn

Poziotinib and Ramucirumab for the Treatment of EGFR Exon 20 Mutant Stage IV Non-small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8
Betta Pharmaceuticals Co., Ltd.
Tigermed Consulting Co., Ltd

Completed

Icotinib Hydrochloride Cream in Patients With Mild to Moderate Psoriasis

Psoriasis

China
Epygenix

Completed

Study of Safety and Pharmacokinetics of Oral Doses of EPX-100 in Healthy Subjects.

Dravet Syndrome

United States
Janssen Research & Development, LLC

Completed

An Observational Study of Men With Premature Ejaculation Who Are Treated With Dapoxetine Hydrochloride or Alternate Care Defined as Any Treatment Other Than Dapoxetine Hydrochloride

Sexual Dysfunction, Physiological | Ejaculation

Germany, Spain, Portugal, Finland, Sweden, Austria
Advanz Pharma

Completed

A Study of the Efficacy and Safety of Vernakalant Hydrochloride (MK-6621) in Patients With Atrial Fibrillation (MK-6621-010 AM4)

Atrial Fibrillation
National Cancer Institute (NCI)

Active, not recruiting

Copanlisib Hydrochloride and Nivolumab in Treating Patients With Recurrent or Refractory Diffuse Large B-cell Lymphoma or Primary Mediastinal Large B-cell Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal Large B-Cell Lymphoma | Refractory Primary Mediastinal Large B-Cell Lymphoma

United States
Peking University Third Hospital

Not yet recruiting

Anlotinib , Penpulimab Combined With SBRT for Metastatic Non-Small Cell Lung Cancer (NSCLC)

Non-Small Cell Lung Cancer
WPD Pharmaceuticals Sp. z o.o.
Worldwide Clinical Trials

Not yet recruiting

A Multicenter, Study of the Safety and Pharmacokinetics of Intravenously Infused Berubicin in Pediatric Patients With Progressive, Refractory, or Recurrent High Grade Gliomas

High Grade Glioma
PhytoHealth Corporation

Completed

Bioavailability, Pharmacokinetics and Safety Evaluation of Phencynonate Hydrochloride in Healthy Volunteers

Healthy

Taiwan
Zhejiang University
Huashan Hospital; West China Hospital; The First Affiliated Hospital of Zhengzhou... and other collaborators

Terminated

A Multicenter Study of Anlotinib in Hepatocellular Carcinoma (HCC) Patients at High Risk of Post Surgery Recurrence

Hepatocellular Carcinoma

China
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Enzastaurin in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer or Primary Peritoneal Cancer

Ovarian Cancer | Primary Peritoneal Cavity Cancer

United States
National Institute of Allergy and Infectious Diseases...
International Tuberculosis Research Center

Withdrawn

Pimonidazole Hydrochloride to Detect Low Oxygen in Tuberculosis-Infected Lungs

Refractory Pulmonary Tuberculosis

Korea, Republic of

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