Search clinical trials for: Naproxen-esomeprazole

Total 1126 results

Janssen-Cilag International NV

Completed

A Study in Healthy Participants to Evaluate the Effects of Multiple Doses of JNJ-55308942 on Cytochrome P450 Substrate Activity and on the Pharmacokinetics of Levonorgestrel/Ethinyl Estradiol

Healthy

Belgium
Tanta University

Unknown

A Two Week Nitazoxanidebased Quadruple Regimen

Dyspepsia

Egypt
Pfizer

Recruiting

A Study to Learn How Different Amounts of PF-06954522 Are Tolerated and Act in Adults With Type 2 Diabetes Mellitus

Obesity | Type 2 Diabetes Mellitus (T2DM)

United States
Zagazig University

Recruiting

Intralesional Voriconazole, or Intralesional Cryotherapy, or Oral Doxycycline in the Treatment of Cutaneous Leishmaniasis

Leishmaniasis, Cutaneous

Libyan Arab Jamahiriya
Providence Health & Services
Brooklyn ImmunoTherapeutics, LLC

Active, not recruiting

Pre-operative IRX-2 in Early Stage Breast Cancer (ESBC)

Breast Neoplasm | Triple Negative Breast Cancer | Breast Neoplasm, Male

United States
Boehringer Ingelheim

Completed

Interaction of BI 425809 With Midazolam, Warfarin, Omeprazole and Digoxin

Healthy

Germany
Alexion

Completed

A Study of ALXN1840 (Coated and Non-coated) Administered With And Without Omeprazole In Healthy Adults

Healthy

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Effect of Single and Repeated Oral Doses of ACT-539313 on What the Body Does to Flurbiprofen, Omeprazole, Midazolam in Healthy Subjects

Healthy

Germany
James J. Peters Veterans Affairs Medical Center

Unknown

GERD and Anti-Reflux Therapy Between Able-bodied and SCI Individuals

Gastro Esophageal Reflux Disorder

United States
Radboud University Medical Center

Completed

Phenotyping of High Dose Rifampicin (PHENORIF)

Tuberculosis

South Africa
University Hospital, Basel, Switzerland

Completed

Pharmacokinetic Study to Investigate Low-dose Combinations of a Cocktail of Seven Drugs for Simultaneous Phenotyping of Cytochromes

Pharmacokinetics | Cytochrome

Switzerland
Jules Desmeules

Completed

Evaluation of the Potential Pharmacokinetic Interactions Between Probe Drugs in the Geneva Phenotyping Cocktail

Drug Interaction

Switzerland
Cognition Therapeutics

Completed

Drug Interaction Study of CT1812 in Healthy Volunteers

Healthy Volunteers

United States
Daiichi Sankyo, Inc.

Completed

A PHASE 1, OPEN-LABEL, CROSS-OVER, FIXED SEQUENCE STUDY TO EVALUATE THE EFFECT OF MULTIPLE DOSES OF DS-1971A ON THE SINGLE DOSE PHARMACOKINETICS OF PROBE SUBSTRATES FOR CYP2B6, CYP2C8, CYP2C9, CYP2C19 AND CYP3A4 ENZYMES IN HEALTHY MALE AND FEMALE SUBJECTS

Healthy

United Kingdom
University of California, San Francisco
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Chemopreventive Therapy for Malaria in Ugandan Children (PROMOTE-Chemop)

Malaria

Uganda
Brooklyn ImmunoTherapeutics, LLC

Completed

A Phase 2 Clinical Trial of the Safety and Effects of IRX-2 in Treating Patients With Operable Head and Neck Cancer

Squamous Cell Carcinoma of the Head and Neck
University of Southern Denmark
Odense University Hospital; Region Syddanmark; Association of Danish Physiotherapists and other collaborators

Completed

The Effect on Knee Joint Loads of Analgesic Use Compared With Exercise in Patients With Knee Osteoarthritis - An RCT (EXERPHARMA)

Osteoarthritis, Knee

Denmark
University of Southern California
National Cancer Institute (NCI); Brooklyn ImmunoTherapeutics, LLC

Active, not recruiting

IRX-2 Regimen in Treating Women With Cervical Squamous Intraepithelial Neoplasia 3 or Squamous Vulvar Intraepithelial Neoplasia 3

Cervical Squamous Cell Carcinoma In Situ | Vulvar High Grade Squamous Intraepithelial Lesion

United States
Alexion Pharmaceuticals
Achillion, a wholly owned subsidiary of Alexion

Completed

A Study of the Drug Interactions Between Danicopan and Cyclosporine, Tacrolimus, Antacids, and Omeprazole in Healthy Adults

Healthy

United States
Sherief Abd-Elsalam
Tanta University

Unknown

Study of Nitazoxanide (NTZ) Based New Therapeutic Regimens for Helicobacter Pylori

Helicobacter-associated Gastritis

Egypt
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of a Single Dose of CNTO 136 (Sirukumab) on CYP450 Enzyme Activities After Subcutaneous Administration in Patients With Rheumatoid Arthritis

Arthritis, Rheumatoid

Germany, Korea, Republic of, South Africa, Moldova, Republic of
Sahlgren´s University Hospital
Sahlgrenska University Hospital, Sweden

Withdrawn

Pain as Indication for Operative Treatment of Traumatic Rib Fractures (potf)

Pain | Trauma | Surgery | Rib Fractures

Sweden
ViiV Healthcare

Completed

Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy Adults

HIV Infections

United States
Brooklyn ImmunoTherapeutics, LLC

Completed

IRX-2 Regimen in Patients With Newly Diagnosed Stage II, III, or IVA Squamous Cell Carcinoma of the Oral Cavity (INSPIRE)

Squamous Cell Carcinoma of the Oral Cavity

United States, Brazil, United Kingdom, Canada
Boehringer Ingelheim

Completed

A Study in Healthy People to Test Whether BI 730357 Influences the Amount of Caffeine, Warfarin, Omeprazole, and Midazolam in the Blood

Healthy

Germany
Pfizer
Pierre Fabre Laboratories

Active, not recruiting

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Advanced Solid Tumors | Metastatic Melanoma

United States, Spain, Belgium, Canada, Netherlands
Sahlgren´s University Hospital
Karolinska University Hospital; Sahlgrenska University Hospital, Sweden

Completed

Operative Treatment of Unstable Thoracic Cage Injuries and Chest Wall Deformity in Trauma

Trauma | Surgery | Flail Chest | Rib Fractures

Sweden
AstraZeneca

Completed

Study to Assess the Effect of Co-Administration of AZD9833 on the Pharmacokinetics of Midazolam, of Omeprazole, of Celecoxib and of Dabigatran Etexilate in Healthy Postmenopausal Female Volunteers

Healthy Volunteers

United States
Eli Lilly and Company

Completed

A Study of LY3484356 in Healthy Female Participants

Healthy

United States
Corcept Therapeutics

Completed

Study in Healthy Subjects to Determine the Effect of Relacorilant on Exposure to Probe Substrates for Cytochrome P450s

Healthy

United States
Pfizer

Completed

A Study to Estimate the Effect of Multiple Dose Abrocitinib on Caffeine, Efavirenz, and Omeprazole in Healthy Participants

Healthy Participants

United States
Acerta Pharma BV

Completed

A Study to Evaluate the One-way Interaction of Calcium Carbonate, Omeprazole, or Rifampin on ACP-196

Healthy Participants

United States
Janssen Research & Development, LLC

Completed

Pharmacokinetic Study to Evaluate the Effect of a Single Dose of Guselkumab (CNTO 1959) on CYP 450 Enzyme Activities After Subcutaneous Administration in Participants With Psoriasis

Psoriasis

United States
Jules Desmeules

Completed

Cocktail Approach for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood Spot

Healthy Volunteers

Switzerland
R-Pharm International, LLC
IQVIA RDS Ireland Ltd; Thermo Fisher Scientific FS

Completed

Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Single Dose of Olokizumab on the Pharmacokinetics of Substrates for CYP1A2, CYP2C9, CYP2C19 and CYP3A4

Rheumatoid Arthritis

Bulgaria, Moldova, Republic of
Spero Therapeutics

Completed

Study to Examine the Effect of Antacid and Omeprazole on the Single-Dose Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects

Healthy Volunteers

United States
National Institute of Public Health, Slovenia
Community Healthcare Center dr. Adolf Drolc Maribor (HCM)

Enrolling by invitation

Feasibility Study of the Proposed Test-and-treat Screening Program in Younger Participants With H. Pylori Infection

Helicobacter Pylori Infection

Slovenia
University Hospital, Geneva

Unknown

Drug Metabolism and Antidepressant (METADEP)

Depression

Switzerland
The University of Texas Health Science Center,...
National Center for Advancing Translational Sciences (NCATS)

Completed

MAST Trial: Multi-modal Analgesic Strategies in Trauma (MAST)

Nonspecific Pain Post Traumatic Injury

United States
University of Illinois at Chicago
UCB Pharma

Completed

IL-7 and IL-7R Expression in RA Patients With Active vs. Inactive Disease Treated With DMARD or CIMZIA

Rheumatoid Arthritis

United States
AstraZeneca
Parexel

Terminated

A Study to Assess the Effects of Itraconazole, Rifampicin, and Omeprazole on Pharmacokinetics of Adavosertib

Advanced Solid Tumours

United States, Spain
AbbVie
Boehringer Ingelheim

Completed

This Study Tests the Effect of Risankizumab on the Metabolism in the Liver of Five Additional Drugs to Study Possible Drug Interactions in Patients With Psoriasis With or Without Psoriatic Arthritis

Psoriasis

Germany
Boehringer Ingelheim

Recruiting

A Study to Compare How Different Substances (Caffeine, Warfarin, Omeprazole, Metoprolol, and Midazolam) Are Handled by the Body of Healthy People and People With Liver Cirrhosis

Liver Cirrhosis

Germany
LEO Pharma

Completed

Drug-drug Interaction Trial With Tralokinumab in Moderate to Severe Atopic Dermatitis - ECZTRA 4

Atopic Dermatitis

United States, France, Netherlands
Regeneron Pharmaceuticals
Sanofi

Completed

Open Label, Drug-Drug Interaction (DDI) Study of Dupilumab (REGN668/SAR231893) in Patients With Moderate to Severe Atopic Dermatitis (AD)

Atopic Dermatitis

United States
Merck Sharp & Dohme LLC

Completed

A Single-Dose Study to Investigate the Pharmacokinetics of MK-7655 in Participants With Impaired Renal Function (MK-7655-005)

Infectious Disease
Kadmon Corporation, LLC
Quotient Sciences

Completed

Drug-drug Interaction Between Belumosudil, Itraconazole, Rifampicin, Rabeprazole, and Omeprazole in Healthy Volunteers

Autoimmune Diseases | Drug-drug Interaction | Fibrotic Disease

United Kingdom
Celgene

Completed

A Study to Evaluate the Effect of Multiple Doses of CC-90001 on the Pharmacokinetics of Omeprazole, Midazolam, Warfarin, Rosuvastatin, Metformin, Digoxin, and Nintedanib in Healthy Adult Subjects

Heathy Volunteer

United States
Biogen

Completed

An Open-Label Immunogenicity and Pharmacokinetics Study of Daclizumab High Yield Process Prefilled Syringe in Relapsing Remitting Multiple Sclerosis (OBSERVE)

Relapsing-Remitting Multiple Sclerosis

Poland, Hungary, United States, Czech Republic
Takeda

Withdrawn

Phase 4, Vedolizumab-4002 Post-marketing, Disease-Drug-Drug Interaction Study

Crohn Disease | Colitis, Ulcerative

United States

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