Search clinical trials for: Nicotinic Antagonists

Total 34665 results

University of Maryland, Baltimore
National Institute on Drug Abuse (NIDA)

Completed

Nicotinic Modulation of the Default Network

Magnetic Resonance Imaging | Cognition | Nicotine | Mecamylamine

United States
US Department of Veterans Affairs

Completed

Treatment to Quit Smoking

Smoking

United States
University of Vermont
Vanderbilt University Medical Center

Completed

The Nicotinic Cholinergic System and Cognitive Aging

Healthy Aging

United States
University of Maryland, Baltimore

Withdrawn

Effects of Prazosin on the Attention-Enhancing Effects of Nicotine

no Condition, Basic Science
Centre for Addiction and Mental Health
Ontario Ministry of Health and Long Term Care

Completed

Phase I Study: Stop Smoking Therapy for Ontario Patients (STOP)

Smoking

Canada
Mclean Hospital

Withdrawn

Effects of Progesterone on IV Nicotine Induced Changes on BOLD fMRI Signal, Hormones and Subjective Ratings of Stimulant Drugs

Nicotine Dependence

United States
Mclean Hospital

Withdrawn

Effects of Progesterone on IV Nicotine-Induced Changes in Hormones and Subjective Ratings of Stimulant Drug Effect

Nicotine Dependence

United States
Florida International University

Recruiting

Assessing the Effect of Nicotine Reduction on ENDS User's Addiction and Exposures

Electronic Cigarette Use

United States
Yale University
American University of Beirut Medical Center

Recruiting

Nicotine Flux, a Potentially Powerful Tool for Regulating Nicotine Delivery From Electronic Cigarettes

Nicotine Vaping

United States
RAI Services Company

Completed

CSD201004: An Actual Use Study of P10 and P13 Nicotine Pouches Among U.S. Adult Smokers

Smoking | Tobacco Use | Tobacco Smoking

United States
University of Nebraska
Institute for Science and Health

Completed

Validation of Biomarkers of Exposure and Host Response

Cigarette Smoker

United States
McNeil AB

Completed

Multiple-dose Nicotine Pharmacokinetics With a New Oral Nicotine Replacement Product.

Tobacco Dependence

Sweden
Vanderbilt University Medical Center

Completed

Nicotine Treatment of Cognitive Decline in Down Syndrome

Down Syndrome | Mild Cognitive Impairment

United States
University of Kansas Medical Center
Patient-Centered Outcomes Research Institute

Completed

Smoking Cessation Versus Long-term Nicotine Replacement Among High-risk Smokers

Smoking | Pulmonary Disease, Chronic Obstructive | Tobacco Use Disorder

United States
Yale University

Recruiting

IV Pulsed-Nicotine as a Model of Smoking: The Effects of Dose and Delivery Rate

Nicotine Dependence

United States
RAI Services Company

Not yet recruiting

CSD231005 Nicotine Pouch Biomarkers of Exposure

Smoking | Tobacco Use

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Reduced Nicotine Cigarette Purchasing Decisions

Tobacco Use Disorder

United States
University of Wisconsin, Madison
National Cancer Institute (NCI); University of Illinois at Chicago; Aurora Health... and other collaborators

Completed

Identifying Treatments to Motivate Smokers to Quit (Motivation)

Smoking | Smoking Cessation | Nicotine Dependence | Motivation

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking

Kidney Cancer | Cervical Cancer | Leukemia | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Tobacco Use Disorder | Lung Cancer | Bladder Cancer | Liver Cancer

United States
Brown University

Active, not recruiting

Using ANDS to Reduce Harm for Low SES Cigarette Smokers

Nicotine Dependence | Smoking, Cigarette

United States
National Institute on Drug Abuse (NIDA)
National Cancer Institute (NCI)

Completed

Comparisons of Nicotine-free Cigarettes, Extra Low Nicotine Cigarettes vs. Medicinal Nicotine

Tobacco Dependence

United States
GlaxoSmithKline

Completed

A Single Dose Bioequivalence Study OfTwo Formulations Of Nicotine Lozenges

Healthy Volunteer Smokers
University of California, San Francisco
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine

Nicotine Dependence | Nicotine Vaping

United States
Yale University
American Heart Association

Completed

Internet-Administered Smoking Cessation Treatment for Overweight and Obese Smokers

Smoking Cessation | Obesity | Overweight

United States
Centre for Addiction and Mental Health
Canadian Cancer Society (CCS)

Recruiting

Smoking Cessation and Menstrual Cycle Phase (MC-NRT)

Smoking Cessation | Tobacco Smoking | Substance Use Disorders | Nicotine Dependence | Nicotine Use Disorder

Canada
Milton S. Hershey Medical Center

Not yet recruiting

Use of Nicotine Pouches Among Daily Smokers

Tobacco Dependence

United States
University of Minnesota
National Institute on Drug Abuse (NIDA); National Cancer Institute (NCI)

Completed

Novel Determinants and Measures of Smokeless Tobacco Use: Study 2

Tobacco Use Disorder | Nicotine Dependence

United States
Universita degli Studi di Catania
Lega Italiana Anti Fumo

Not yet recruiting

Smoking Cessation And Reduction in Depression (scarid)

Tobacco Smoking in Depressed Patients

Italy
Universita degli Studi di Catania

Not yet recruiting

Antismoking Effects of Electronic Cigarettes in Subjects With Schizophrenia and Their Potential Influence on Cognitive Functioning. (SCARIS)

Tobacco Smoking in Schizophrenic Patients
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI)

Completed

UW Withdraw From Tobacco Study

Tobacco Dependence

United States
University of California, Los Angeles

Completed

E-cigarettes, Nicotine Inhaler, and Blood Vessel Function

Nicotine Dependence

United States
Ohio State University
American Heart Association; Optum, Inc.

Recruiting

Research and Innovation to Stop E-cigarette/Vaping in Young Adults ((RISE))

Nicotine Dependence | E-Cig Use

United States
University of Minnesota

Completed

Palatability of Experimental Cigarettes - Study 2

Smoking

United States
Wake Forest University Health Sciences
National Institute on Drug Abuse (NIDA)

Completed

Project 2: Strategies for Reducing Nicotine Content in Cigarettes

Tobacco Smoking | Nicotine Dependence

United States
McNeil AB

Completed

Cumulative Skin Irritation Potential of a New 15 mg Nicotine Patch

Smoking Cessation

Germany
University of Oklahoma
National Institute on Drug Abuse (NIDA); Duke University; National Institutes... and other collaborators

Not yet recruiting

Beta-Adrenergic Modulation of Drug Cue Reactivity

Tobacco Use Disorder | Nicotine Dependence | Cigarette Smoking

United States
Duke University
Philip Morris USA, Inc.

Completed

Meclizine as a Potential Smoking Cessation Treatment

Smoking Cessation

United States
University of Minnesota
University of Pennsylvania; Brown University; Duke University; University of California... and other collaborators

Completed

Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace

Tobacco Smoking | Nicotine Dependence

United States
University of Kansas Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Changing the Default for Tobacco Treatment

Tobacco Use Cessation

United States
McNeil AB

Completed

Single-dose Nicotine Pharmacokinetics With a New Oral Nicotine Replacement Product

Tobacco Dependence

Sweden
National Institute on Drug Abuse (NIDA)

Recruiting

Defining Neurobiological Links Between Substance Use and Mental Illness

Substance Use Disorder | Major Depressive Disorder | Normal Physiology

United States
University of Minnesota
Brown University; Hennepin County Medical Center, Minneapolis

Completed

Treating Smokers With Mental Illness

Psychotic Disorders | Smoking Cessation | Schizophrenia | Major Depressive Disorder | Mental Illness | Cigarette Smoking | Bipolar Disorder I | Bipolar II Disorder

United States
Medical University of South Carolina

Completed

Quit or Switch: E-cigarette Study

Tobacco Use

United States
Montefiore Medical Center
Johns Hopkins University; Westat

Completed

RCT of an Internet Cessation Program Plus Online Social Network for HIV+ Smokers (PSFW+)

Tobacco Use Disorder | HIV

United States
Medical University of South Carolina

Completed

Salt-Based E-cigarette

Smoking | Tobacco Use

United States
Hospital Authority, Hong Kong
Chinese University of Hong Kong

Completed

Comparing the Effectiveness of Combined NRT With Single NRT in Primary Care Clinics in Hong Kong

Smoking Cessation
Milton S. Hershey Medical Center

Completed

Pharmacokinetics of Nicotine Film in Smokers

Smoking Cessation

United States
National Institute on Drug Dependence, China
Bronx VA Medical Center

Completed

Association of Functional COMT Val108/Met Polymorphism With Smoking Cessation in Nicotine Replacement Therapy

Nicotine Dependence
University of Texas at Austin

Completed

Smoking Cessation and Sexual Health in Men

Smoking Cessation

United States
University of Memphis

Completed

Nicotine Patch Trial in Syrian Primary Care Settings

Smoking Cessation

Syrian Arab Republic

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