Search clinical trials for: Nucleic Acid Synthesis Inhibitors

Total 16290 results

Dr Joanne CHIU

Recruiting

Pembrolizumab, Lenvatinib and Chemotherapy After TKIs in NSCLC

ALK Gene Rearrangement Positive | EGF-R Positive Non-Small Cell Lung Cancer | EGFR Activating Mutation | Nsclc | ROS1 Gene Rearrangement | ROS1 Positive NSCLC - Reactive Oxygen Species 1 Positive Non-Small Cell Lung Cancer

Hong Kong
Hikma Pharmaceuticals LLC

Terminated

Randomized Comparative Study of Erlotinib and Pemetrexed in the Maintenance Treatment of Advanced Lung Cancer Patients.

Carcinoma, Non-Small-Cell Lung

Lebanon, Jordan
ADDMEDICA SASA

Completed

Acceptability of a New Paediatric Formulation of Hydroxycarbamide in Children With Sickle Cell Disease.

Sickle Cell Disease

France
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Telbivudine 600mg Tablets in Chinese Patients With Chronic Hepatitis B (Chinese PAC)

Chronic Hepatitis B

China
Novartis

Completed

Efficacy and Safety of Oral Famciclovir in Patients With Active Recurrent Genital Herpes

Recurrent Genital Herpes

Australia
National Institute of Allergy and Infectious Diseases...
Oclassen Pharmaceuticals

Completed

The Tolerance of HIV-Infected Patients With Herpes Group Virus Infections to Oral Doses of FIAU

HIV Infections | Hepatitis B | Herpes Simplex

United States
Duke University

Completed

Hydroxyurea in Young Children With Sickle Cell Anemia

Sickle Cell Anemia

United States
Henan Cancer Hospital
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Study of Apatinib as the Maintenance Therapy in Advanced Lung Adenocarcinoma

Lung Adenocarcinoma

China
Astra USA

Completed

Phase III Multicenter, Open-Label, Randomized Trial of Induction Versus Induction Plus Maintenance Foscarnet ( Foscavir ) Therapy for Gastrointestinal CMV Disease

Gastrointestinal Diseases | HIV Infections

United States
University of Kinshasa
KU Leuven

Completed

Hydroxyurea Treatment for Adult Sickle Cell Anemia Patients in Kinshasa

Sickle-Cell Anaemia

Congo, The Democratic Republic of the
UNICANCER

Completed

Hydroxyurea in Treating Patients With Recurrent and/or Unresectable Meningioma

Brain and Central Nervous System Tumors

France
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); George Papanicolaou Hospital

Completed

Evaluating the Safety of G-CSF Mobilization in Individuals With Beta Thalassemia Major

Beta-Thalassemia

Greece
St. Jude Children's Research Hospital

Completed

Hydroxyurea in Treating Patients With Epstein-Barr Virus-Associated Primary CNS Lymphoma and AIDS

Lymphoma

United States
Novartis

Completed

A Study to Evaluate the Safety and Efficacy of Single Day or Single Dose Famciclovir for the Treatment of Recurrent Herpes Labialis

Recurrent Herpes Labialis
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

Camrelizumab Combined With Pemetrexed and Carboplatin for the Study of EGFR-mutated Lung Squamous NSCLC Treatment

Lung Cancer Stage II
Fudan University

Completed

Pemetrexed and Platinum Use in the Neoadjuvant Setting for Resectable Stage II and IIIA Lung Adenocarcinoma (ECTOP-1002)

Lung Adenocarcinoma

China
Chonnam National University Hospital
Pusan National University Hospital; Korea University Guro Hospital; Kyungpook... and other collaborators

Completed

Efficacy and Safety of Adjuvant Pemetrexed Plus Cisplatin for Adenocarcinoma of Lung (APICAL)

Adenocarcinoma | Lung Neoplasm

Korea, Republic of
Tianjin Medical University Cancer Institute and...

Unknown

Almonertinib With Chemotherapy in mEGFR NSCLC

Non-Small Cell Lung Cancer Metastatic

China
Fudan University

Unknown

Almonertinib/Pemetrexed/Carboplatin in EGFR T790M+ Advanced Lung Cancer (APPEAL)

Lung Cancer, Non-small Cell | EGFR Gene Mutation | EGFR T790M

China
OncoMed Pharmaceuticals, Inc.
Celgene Corporation

Completed

A Study of Carboplatin, Pemetrexed Plus Placebo vs Carboplatin, Pemetrexed Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With Non-Squamous Non-Small Cell Lung Cancer (DENALI)

Nonsquamous Nonsmall Cell Neoplasm of Lung

Spain, United States, Australia, Italy, Belgium
Boehringer Ingelheim

Completed

Trial of BI 6727 (Volasertib) Monotherapy and BI 6727 in Combination With Pemetrexed Compared to Pemetrexed Monotherapy in Advanced NSCLC

Carcinoma, Non-Small-Cell Lung

Bahamas, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Pemetrexed Disodium in Treating Young Patients With Recurrent Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific

United States, Canada
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Cisplatin With or Without Pemetrexed Disodium in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot be Removed by Surgery

Malignant Mesothelioma

United States
Sun Yat-sen University
Eli Lilly and Company

Completed

Study of Alimta in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC) Who Have Had Prior Platinum Based Chemotherapy

Nasopharyngeal Neoplasms

China
Eli Lilly and Company

Completed

A Study of Pemetrexed and Folic Acid Given Before Surgery (Neoadjuvant Treatment) to Patients With Rectal Cancer.

Rectal Neoplasms

Sweden
Eli Lilly and Company

Completed

Pemetrexed as the First Treatment in Advanced or Metastatic Breast Cancer

Breast Cancer | Breast Neoplasms, Male | Carcinoma, Ductal

United States
Eli Lilly and Company

Completed

Trial of Pemetrexed for Patients With Pancreatic Cancer Which Cannot be Treated With Surgery or is Metastatic

Pancreatic Cancer

Germany
AstraZeneca

Recruiting

A Study of Osimertinib With or Without Chemotherapy Versus Chemotherapy Alone as Neoadjuvant Therapy for Patients With EGFRm Positive Resectable Non-Small Cell Lung Cancer (NeoADAURA)

Non-Small Cell Lung Cancer

China, United States, Chile, Vietnam, Thailand, Brazil, Bulgaria, Canada, Germany, India, Japan, Korea, Republic of, Poland, Russian Federation, Singapore, Turkey, Austria, Israel, Spain, Taiwan, Mexico, France, Italy, Peru, Switzerland, United...
Novartis Pharmaceuticals

Terminated

Study Evaluating Efficacy and Safety of Capmatinib in Combination With Osimertinib in Adult Subjects With Non-small Cell Lung Cancers as Second Line Therapy (GEOMETRY-E)

Carcinoma, Non-Small-Cell Lung

Japan, Korea, Republic of, Singapore
Guangzhou Medical University

Recruiting

Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer

Leptomeningeal Metastasis

China
Lantern Pharma Inc.

Recruiting

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma (HARMONIC)

Carcinoma, Non-Small-Cell Lung | Adenocarcinoma of Lung

United States
Xinqiao Hospital of Chongqing

Withdrawn

Efficacy and Safety of Maintenance Apatinib Combined With Pemetrexed in Advanced Non-squamous Non-small Cell Lung Cancer Patients (XQonc-007)

Advanced Non-squamous Non-small-cell Lung Cancer

China
National Institute of Allergy and Infectious Diseases...

Completed

Foscarnet Treatment of Serious CMV Retinitis Infection in Patients With Acquired Immunodeficiency Syndrome

HIV Infections | Cytomegalovirus Retinitis

United States
Jiangsu Province Nanjing Brain Hospital

Recruiting

The Dynamic Monitoring of Cerebrospinal Fluid ctDNA

NSCLC

China
Tang-Du Hospital

Recruiting

Neoadjuvant Furmonertinib and Cisplatin/Pemetrexed as in EGFR Mutated Stage IIIA-IIIB Resectable NSCLC (FORESEE)

Non-small Cell Lung Cancer

China
Central European Cooperative Oncology Group

Terminated

Dacomitinib + Pemetrexed for Patients With Advanced Non-squamous Non-small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer

Austria
Fudan University

Unknown

Pemetrexed and Carboplatin With or Without Anlotinib Hydrochloride for Osimertinib-resistant Non-squamous NSCLC (PCA)

NSCLC Stage IV

China
Eli Lilly and Company

Completed

A Study of Advanced or Metastatic Non-small Cell Lung Cancer

Non Small Cell Lung Cancer

United States, Taiwan, Italy, Korea, Republic of
Guangdong Association of Clinical Trials

Unknown

Anlotinib Plus Pemetrexed or Pemetrexed for Previously Untreated Elderly (>=70) or PS=2 Non-squamous NSCLC

Advanced Non-squamous NSCLC

China
Universität Duisburg-Essen
Eli Lilly and Company

Unknown

Cisplatinum/Pemetrexed Versus Split-dose Cisplatinum/Pemetrexed In NSCLC (PemSplitCisp)

NSCLC

Germany
CASI Pharmaceuticals, Inc.

Completed

Safety Study of MKC-1 Combined With Pemetrexed to Treat Advanced Cancer and Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer | Advanced Cancer

United States
Eli Lilly and Company

Completed

Study of Pemetrexed in Mesothelioma and Lung Cancer Patients With Fluid Around the Lungs or Abdomen

Lung Neoplasms | Mesothelioma | Non-small Cell Lung Cancer

Spain, Germany, Denmark
Eli Lilly and Company
Gynecologic Oncology Group

Completed

A Trial for Patients With Advanced/Recurrent Endometrial Cancer

Neoplasms | Urogenital Neoplasms | Neoplasms by Site | Uterine Neoplasms | Genital Neoplasms, Female | Endometrial Neoplasms | Endometrial Cancer | Endometrium Cancer | Cancer of Endometrium | Cancer of the Endometrium | Neoplasms, Endometrial

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Additional Chemotherapy After Surgery for People With Malignant Peritoneal Mesothelioma

Mesothelioma | Mesothelioma, Malignant | Malignant Mesothelioma | Peritoneal Mesothelioma | Malignant Peritoneal Mesothelioma

United States
Fudan University

Recruiting

Adjuvant Chemotherapy for High Risk Stage I Lung Adenocarcinoma (ECTOP-1004)

Lung Neoplasms

China
Sun Yat-sen University
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Camrelizumab With AC in Patients With Brain Metastases of Driven Gene-negative,NSCLC (CAP-BRAIN)

Brain Metastases | Non-squamous Non-small-cell Lung Cancer

China
Cancer Institute and Hospital, Chinese Academy...
Jiangsu Hansoh Pharmaceutical Co., Ltd.; GeneCast Biotechnology Co., Ltd.

Enrolling by invitation

Efficacy and Safety of Almonertinib Combined With or Without Chemotherapy as an Adjuvant Treatment for Stage II-IIIA Non-small Cell Lung Carcinoma Following Complete Tumour Resection (APEX)

Non-small Cell Lung Carcinoma

China
Centre Georges Francois Leclerc

Completed

Pemetrexed in Maintenance in Patients With Impaired Renal Function, 2 Dose Calculation Strategies (PKAPIR)

Non-small Cell Lung Cancer

France
Henan Provincial People's Hospital
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Study of Anlotinib Combined With Pemetrexed in Patients With Advanced Nonsquamous NSCLC (ALTER-L025)

Non-squamous Cell Non-Small Cell Lung Cancer

China
Eli Lilly and Company
Gynecologic Oncology Group

Completed

A Study of Single Agent Pemetrexed Disodium in Treating Patients With Recurrent or Persistent Ovarian or Primary Peritoneal Cancer

Ovarian Cancer | Peritoneal Cancer

United States

Search clinical trials for: Nucleic Acid Synthesis Inhibitors

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