Search clinical trials for: Opioid antagonist

Total 36246 results

Clayton Petro

Recruiting

No Opioids vs. Minimal Opioids Following Inguinal Hernia Repair

Postoperative Pain | Inguinal Hernia

United States
National Institute on Drug Abuse (NIDA)
Johns Hopkins University

Terminated

Opioid Agonist and Antagonist Effects on Opioid Dependence

Opioid-Related Disorders

United States
University of Kent
Kent Community Health NHS Foundation Trust; NHS Kent and Medway

Recruiting

DE-eSCALation of Opioids Post-surgical dischargE (DESCALE)

Opioid Dependence

United Kingdom
OrthoCarolina Research Institute, Inc.

Active, not recruiting

Opioid-Free Orthopaedic Surgery (CORE)

Pain Management

United States
Leslie Thomas
American Society of Anesthesiologists

Withdrawn

A Comparison of Two Pain Control Techniques on Deliruim in Hip Fracture Patients

Hip Fracture

United States
Vertanical GmbH

Active, not recruiting

Comparison of VER-01 to Opioids in Patients With Chronic Non-specific Low Back Pain (ELEVATE)

Chronic Non-specific Low Back Pain

Germany
Alza Corporation, DE, USA

Completed

An Open-Label Evaluation of the Independent Effects of Coadministration of a High-Fat Meal and Naltrexone Blockade on the Pharmacokinetic Profile of Dilaudid OROS (Hydromorphone HCI) 16mg

Analgesia
Eli Lilly and Company

Completed

A Study of Brain Receptor Occupancy in Healthy Subjects

Alcohol Dependence

United States
University of Alabama at Birmingham

Completed

Increasing Naloxone Access for Persons Who Use Opioids

Naloxone

United States
University of Missouri-Columbia

Not yet recruiting

Opioid Rapid Response System: Naloxone Training in Communities

Opioid Overdose
St. Elizabeth Medical Center, Utica, NY
Halyard Health

Completed

Opioid-free Accelerated Recovery Total Knee Arthroplasty

Arthropathy of Knee Joint

United States
HealthPartners Institute
National Institute on Drug Abuse (NIDA); Hennepin Healthcare Research Institute

Completed

Clinical Decision Support for Opioid Use Disorders in Medical Settings: Usability Testing in an EMR (COMPUTE)

Opioid-use Disorder

United States
Mahidol University

Unknown

0.05 Versus 0.1 mg Spinal Morphine for Reducing Morphine Requirement After Vaginal Hysterectomy

Pain | Vaginal Hysterectomy

Thailand
Mahidol University

Completed

Opioid Withdrawal Symptoms in Critically Ill Patients

Critical Illness | Substance Withdrawal Syndrome

Thailand
University Hospital, Limoges

Suspended

Procedures of Locoregional Analgesia and Quality of Life in Palliative Care Units (TALViSoP)

Pain

France
University of Washington
National Institute on Drug Abuse (NIDA)

Completed

Pilot Trial of Opioid Taper Support (POTS)

Chronic Non-cancer Pain

United States
University of Colorado, Denver
National Institute on Drug Abuse (NIDA)

Withdrawn

Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-2 - 5

Opioid-Related Disorders | Heroin Dependence

United States
University of Colorado, Denver
National Institute on Drug Abuse (NIDA)

Withdrawn

Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-1 - 4

Opioid-Related Disorders | Heroin Dependence

United States
University of Southern California
Northwestern University; National Institute on Aging (NIA); AltaMed Health Services...

Completed

Application of Economics & Social Psychology to Improve Opioid Prescribing Safety Trial 1: EHR Nudges (AESOPS-T1)

Opioid Abuse, Unspecified

United States
University of Colorado, Denver
National Institute on Drug Abuse (NIDA)

Withdrawn

Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment III) - 3

Opioid-Related Disorders | Heroin Dependence

United States
Massachusetts General Hospital

Completed

Shared Decision Making for Prescription Opioids After Cesarean Delivery

Pregnancy | Cesarean Section | Analgesics, Opioid | Prescriptions

United States
Rhode Island Hospital
Boston Medical Center

Unknown

Safe Opioid Prescription Practice for Patients Discharged From Trauma Services (SOPP)

Opioids | Drug Prescription
Alza Corporation, DE, USA

Completed

An Open-Label Evaluation of the Dose Proportionality of OROS� Hydromorphone HCL Tablets 8mg, 16mg, 32mg, 64mg

Analgesia
Potomac Health Foundations

Completed

Youth Opioid Recovery Support: A Developmentally-specific Intervention for Home Delivery of Extended Release Naltrexone (YORS)

Opioid-Related Disorders

United States
T. John Winhusen, PhD
National Institute on Drug Abuse (NIDA); Eunice Kennedy Shriver National Institute...

Not yet recruiting

Personally-Tailored Opioid-overdose and Medication for Opioid Use Disorder (MOUD) Education (TOME) for Pregnant and Postpartum Persons in MOUD (TOME)

Pregnancy Related | Substance Use | Opioid Use Disorder | Drug Abuse | Drug Addiction | Drug Abuse in Pregnancy
Rothman Institute Orthopaedics

Completed

Prolonged Multimodal Analgesia for Post-Discharge Pain Control After Primary Total Hip Arthroplasty

Osteoarthritis, Hip

United States
University of Pennsylvania

Recruiting

Improving Access to Opioid Use Disorder Treatment Among Marginalized Patients With a Tailored Telehealth Intervention

Opioid Use Disorder

United States
Duke University
Baylor College of Medicine; Yale University; Icahn School of Medicine at Mount... and other collaborators

Completed

Fast-Fail Trials in Mood and Anxiety Spectrum Disorders; Kappa Opioid Receptor Phase 2a (FASTMAS_Kor2)

ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)

United States
Potomac Health Foundations
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH); National Center for Complementary and Integrative Health (NCCIH) and other collaborators

Recruiting

The Youth Opioid Recovery Support (YORS) Intervention (YORS)

Medication Adherence | Opioid-use Disorder

United States
Chinese University of Hong Kong

Completed

Opioids Titration Study in Advanced Cancer Patients in Hong Kong

Pain Control

Hong Kong
Mayo Clinic

Completed

Increasing Awareness of Opioid Disposal in the Orthopedic Patient Population

Knee Total Joint Replacement | Hip Total Joint Replacement

United States
Nationwide Children's Hospital

Completed

Retrospective Femoral Nerve Block Study

Other Reconstructive Surgery

United States
Region Skane
Lund University

Not yet recruiting

Effects on Mortality and Clinical Course of a Patient's Choice Model for Opioid Maintenance Treatment for Opioid Dependence - Evaluation of a System Enabling a Large Expansion of Treatment Providers and Treatment Access

Opioid Dependence | Overdose

Sweden
University of Maryland, Baltimore

Completed

Youth Opioid Recovery Support: Improving Care Systems (YORS)

Opioid-Related Disorders

United States
Montefiore Medical Center

Completed

Comparing Intravenous Hydromorphone to Usual Care

Pain

United States
McGill University Health Centre/Research Institute...

Unknown

Morphine, Dyspnea, Exercise and COPD

Chronic Obstructive Pulmonary Disease

Canada
Butler Hospital

Completed

Treating Chronic Pain in Buprenorphine Patients in Primary Care Settings (BupPain)

Depression | Pain | Substance Use

United States
The New York Academy of Medicine
Johns Hopkins University; University of Miami; Yale University; Brown University; Montefiore Medical Center and other collaborators

Unknown

Buprenorphine and Integrated HIV Care Evaluation

HIV Infections | Opioid-Related Disorders | AIDS

United States
New York University
Centers for Disease Control and Prevention

Active, not recruiting

Opioids and Police Safety Study (OPS)

Opioid Overdose

United States
Universidad Europea de Canarias

Not yet recruiting

Effectiveness of Percutaneous Neuromodulation vs Pharmacological Treatment in Cancer Patients With Anterior Knee Pain

Pain Cancer

Spain
University of Vermont
National Institute on Drug Abuse (NIDA); Johns Hopkins University; University... and other collaborators

Completed

Maternal Opioid Treatment: Human Experimental Research - Data Yield Appropriate Decisions (MOTHER DYAD)

Opioid-use Disorder | Neonatal Abstinence Syndrome | Opioid Withdrawal | Neonatal Opioid Withdrawal Syndrome

United States
KK Women's and Children's Hospital

Completed

Comparison of Epidural Oxycodone and Epidural Morphine

Pruritus

Singapore
Hennepin Healthcare Research Institute
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Recruiting

EXHIT ENTRE Comparative Effectiveness Trial (EXHITENTRE)

Substance Use Disorder | Opioid Use Disorder, Moderate | Opioid Use Disorder, Severe

United States
Salmaniya Medical Complex

Completed

Comparison Between the Caudal Block and Other Methods of Postoperative Pain Relief in Children Undergoing Circumcision (paincontrol)

Pain, Postoperative | Analgesia | Pain, Acute

Bahrain
Benaroya Research Institute
Virginia Mason Hospital/Medical Center

Completed

Opioid-free Anesthesia for Open Cardiac Surgery: A Prospective Randomized Controlled Trial

Anesthesia | Opioid Use | Heart; Surgery, Heart, Functional Disturbance as Result

United States
Mahidol University

Unknown

0.05 mg Versus 0.1 mg Spinal Morphine for Reducing Morphine Requirement After Vaginal Hysterectomy

Pain

Thailand
Rutgers, The State University of New Jersey
University of Maryland, Baltimore; University of Michigan; University of Illinois... and other collaborators

Completed

Opioid Analgesic Reduction Study (OARS) - Pilot (OARS-Pilot)

Post Operative Pain

United States
Milton S. Hershey Medical Center

Terminated

Treatment of Advanced Head and Neck Cancer

Carcinoma, Squamous Cell of Head and Neck

United States
Instituto de Investigación Hospital Universitario...

Completed

Opioid Free Anaesthesia in Oncologic Gynaecological Surgery: Is There Any Benefit?

Breast Cancer | Ovarian Cancer | Cervix Cancer | Endometrial Cancer

Spain
David Sheyn

Active, not recruiting

Opioid Use After Urogynecologic Procedures: Using a Predictive Calculator

Opioid Use | Post Operative Pain | Prolapse Genital

United States

Search clinical trials for: Opioid antagonist

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