Search clinical trials for: Oral MRX-1024

Total 15028 results

Naurex, Inc, an affiliate of Allergan plc

Completed

Study of Safety, Tolerability and Pharmacokinetics of NRX-1074 in Normal Healthy Volunteers (NRX-1074)

Major Depressive Disorder

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Terminated

MRX, Radiation, and Chemotherapy for Patients With Resected Squamous Cell Carcinoma of the Head and Neck

Head and Neck Cancer | Mucositis | Squamous Cell Carcinoma | Resected Head and Neck Cancer
Pfizer
Medivation, Inc.

Completed

A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine)

Huntington Disease | Alzheimer's Disease

United States
Naurex, Inc, an affiliate of Allergan plc

Completed

Study of Intravenous NRX-1074 in Patients With Major Depressive Disorder

Major Depressive Disorder

United States
M.D. Anderson Cancer Center

Completed

Measuring Non-Enhancing Glioblastoma Progression

Glioblastoma | Brain Tumor

United States
Centre for Probe Development and Commercialization

Completed

A Safety and Biodistribution Study of [I-124]-CPD-1028 Injection in Solid Tumours

Cancer

Canada
Eline C. B. Eskes

Recruiting

Magnetic Resonance Spectroscopy in Acid Sphingomyelinase Deficiency (MONACO)

Asmd, Visceral Type

Netherlands
GlaxoSmithKline

Completed

An Open Label, Randomised, Repeat Dose Study to Assess the Pharmacokinetic Performance of Five Ezogabine/Retigabine Modified Release (MR) Formulations at Steady State Compared to the Immediate Release (IR) Formulation.

Epilepsy

United States
Mayo Clinic
National Center for Complementary and Integrative Health (NCCIH)

Enrolling by invitation

Magnetic Resonance Elastography of Myofascial Pain Syndrome

Myofascial Pain

United States
Taiho Oncology, Inc.

Completed

Study Comparing the Bioavailability of TAS-102 Tablets to an Oral Solution Containing Equivalent Amounts of FTD and TPI

Advanced Solid Tumors (Excluding Breast Cancer)

United States
Bettina Mittendorfer

Recruiting

Routine Validation and Reproducibility Testing of Laboratory Measures and Research Techniques Used for Metabolism Research (VAL) (VAL)

Obesity

United States
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Active, not recruiting

Effects of Gender-Affirming Hormone Therapy Among Transgender Women

Cardiovascular Diseases | HIV/AIDS | Transgender Women | Coagulopathy | Metabolic Disease

United States
Chiesi Farmaceutici S.p.A.

Active, not recruiting

Open Label Extension Study of 1 mg/kg Pegunigalsidase Alfa Every 2 Weeks in Patients With Fabry Disease

Fabry Disease

United States, Netherlands, Australia, Hungary, United Kingdom, Canada, Czechia, Finland, France, Italy, Norway, Slovenia, Spain
Chiesi Farmaceutici S.p.A.

Active, not recruiting

Open Label Extension of 2 mg/kg Pegunigalsidase Alfa (PRX-102) Every 4 Weeks in Adult Fabry Disease Patients (Bright51)

Fabry Disease

Belgium, United States, United Kingdom, Italy, Czechia, Denmark, Norway
Taiho Oncology, Inc.

Completed

Study of the Mass Balance of Oral FTD and TPI as Components of TAS-102 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

United States
Viome

Completed

Efficacy of VRx MyBiotics Oral Lozenges

Oral Microbiome Health

United States
University of Michigan

Withdrawn

Magnetic Resonance (MR) Spectroscopy and Diffusion Tensor Imaging in Determining Brain Injury and Subsequent Clinical Outcome in Patients of Moderate Brain Trauma

Brain Trauma

United States
MicuRx
Worldwide Clinical Trials

Completed

Single Dose and Multiple Dose Escalation Trial of an Oral Formulation of MRX-4

Safety
Chugai Pharmaceutical

Completed

Comparative Study (Double-Blind) of MRA for Rheumatoid Arthritis (RA)

Rheumatoid Arthritis
NorthSea Therapeutics B.V.

Completed

A Phase 1, First Time in Humans Study of NST-1024

Hypertriglyceridemia

United Kingdom
Seoul National University Bundang Hospital

Completed

The Efficacy and Safety of "BST104" (Lonicera Flos Extract) in Mild to Moderate Functional Dyspepsia Subjects

Functional Dyspepsia | Irritable Bowel Syndrome

Korea, Republic of
Chiesi Farmaceutici S.p.A.
ICON plc

Recruiting

Study to Evaluate the Safety, PK, PD, and Efficacy of PRX-102 in Japanese Patients With Fabry Disease (RISE)

Fabry Disease

Japan
MicuRx
Worldwide Clinical Trials

Completed

Single Dose Escalation and Multiple Dose Escalation Trial of an Intravenous Formulation of MRX-4

Safety
Shaare Zedek Medical Center
The Hospital for Sick Children; Rambam Health Care Campus; Children's Hospital... and other collaborators

Completed

The ImageKids Study: Developing the pMEDIC and the PICMI

Crohn's Disease

Israel
NYU Langone Health
Naurex, Inc, an affiliate of Allergan plc

Withdrawn

NRX-1074 in Early Course Schizophrenia

Schizophrenia

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Non-Invasive Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy Techniques (MRS) for Assessing Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer

Breast Cancer

United States
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Safety, Efficacy, & PK of PRX-102 in Patients With Fabry Disease Administered Intravenously Every 4 Weeks (BRIGHT)

Fabry Disease

United States, Denmark, Belgium, United Kingdom, Norway, Italy, Czechia
Memorial Sloan Kettering Cancer Center
National Institutes of Health (NIH)

Active, not recruiting

Dynamic Contrast Enhanced MRI (DCE-MRI) Diffusion Weighted MRI (DW-MRI) and Magnetic Resonance Spectroscopy (MRS) of Head and Neck Tumors

Head and Neck Cancer

United States
VA Office of Research and Development

Completed

Justice-Involved Veterans and Moral Reconation Therapy (MRT)

Antisocial Personality Disorder | Substance Use Disorder

United States
University of Texas Southwestern Medical Center
Cancer Prevention Research Institute of Texas

Completed

Clinical Development of MR Spectroscopy and Imaging in Brain Cancers

Malignant Gliomas | Astrocytomas | Oligodendrogliomas

United States
CymaBay Therapeutics, Inc.

Completed

Safety and Efficacy Study of Metaglidasen in Type 2 Diabetes in Patients Suboptimally Controlled on Insulin

Type 2 Diabetes

United States, Israel, Argentina, India
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Dose-ranging Study of PRX-102 in Adult Fabry Disease Patients

Fabry Disease

United States, Serbia, Spain, United Kingdom, Australia, Paraguay
Protalix

Withdrawn

Study to Evaluate the Safety and EffIcacy of PRX-102 on Gastrointestinal Symptoms in Naïve Fabry Disease

Fabry Disease
OHSU Knight Cancer Institute
Radiological Society of North America; Medical Research Foundation, Oregon

Terminated

Magnetic Resonance Imaging (MRI) in the Assessment of Head and Neck Squamous Cell Carcinoma (HNSCC) Response

Head and Neck Cancer

United States
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Safety and Efficacy of PRX-102 in Patients With Fabry Disease Currently Treated With REPLAGAL® (Agalsidase Alfa)

Fabry Disease

Australia, Netherlands, United Kingdom, Canada, Czechia, Norway, Slovenia
University of Exeter

Completed

Can Ultrasound be Used as a Measure of Muscle Quality? A Validation Study Comparing Ultrasound With MRI and MRS in Older and Younger Persons.

Muscle Atrophy

United Kingdom
Shire

Completed

Sophisticated Assessment of Disease Burden in Patients With Fabry Disease (SOPHIA)

Fabry Disease

Finland, Sweden, Germany, Belgium, Czechia, Denmark
Massachusetts General Hospital
President and Fellows of Harvard College; Nutrition Obesity Research Center...

Completed

Mechanisms of Diastolic Dysfunction Among Persons With HIV Compared With Non-HIV Control Subjects

Myocardial Fibrosis | HIV | Diastolic Dysfunction

United States
University of Nottingham

Unknown

Perfusion MRI in Reversible Cerebral Vasoconstriction Syndrome

Reversible Cerebral Vasoconstriction Syndrome

United Kingdom
Protalix
Chiesi Farmaceutici S.p.A.

Completed

Extension Study of PRX-102 for up to 60 Months

Fabry Disease

United States, Spain, United Kingdom, Paraguay
Centre Hospitalier Universitaire, Amiens
Groupe Hospitalier Pitie-Salpetriere

Recruiting

Study of the Relationship Between Clinical, Imaging and Biological Data in Patients With Squamous Cell Carcinoma of the Tongue (ClimaBio)

Squamous Cell Carcinoma | Proton Magnetic Resonance Spectroscopy | Transcriptomics | Soft Tissue Tumors of the Tongue

France
Neurovance, Inc.

Completed

A Study to Evaluate the Safety, Tolerance, and Pharmacokinetic and Pharmacodynamic Profile Of 1 SR Formulation of EB-1020

Normal, Healthy Volunteers

Australia
Jonsson Comprehensive Cancer Center
U.S. Army Medical Research and Development Command; U.S. Army Medical Research...

Completed

MR Correlated Spectroscopic Imaging for Diagnosing Breast Cancer

Breast Carcinoma | Malignant Breast Neoplasm | Benign Breast Neoplasm

United States
Monte Rosa Therapeutics, Inc

Recruiting

Study of Oral MRT-2359 in Selected Cancer Patients

NSCLC | Prostate Cancer | SCLC | DLBCL | High Grade Neuroendocrine Cancer | L-MYC and N-MYC Amplified Solid Tumors | NSCLC With High or Low L-MYC or N-MYC Expression | HR-positive, HER2-negative Breast Cancer

United States, Canada
BioLineRx, Ltd.

Terminated

A Study Intended to Evaluate Safety, Tolerability and Pharmacokinetics (PK) Parameters of BL-1021

Healthy | Volunteers

Israel
University Hospital, Strasbourg, France

Recruiting

Intracranial Arterial Stenosis and Resin of Cannabis Use

Cannabis Users

France
University of Zurich

Completed

Seated Evaluation of Anorectal funcTion by High Resolution Anorectal Manometry (SEAT)

Incontinence | Anismus

Switzerland
The HIV Netherlands Australia Thailand Research...
Chulalongkorn University; University of Hawaii; South East Asia Research Collaboration... and other collaborators

Completed

Neurocognitive Impairment and Psychiatric Comorbidities in HIV-1

HIV Infections

Thailand
Gilead Sciences

Completed

Study to Evaluate the Safety and Efficacy of Teropavimab and Zinlirvimab in Combination With Lenacapavir (GS-6207) in Virologically Suppressed Adults With HIV-1 Infection

HIV-1 Infection

United States
Cedars-Sinai Medical Center

Completed

Identification of Adverse Plaque Characteristics by Coronary MR Angiography

Coronary Artery Disease

United States

Search clinical trials for: Oral MRX-1024

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