Search clinical trials for: PEG- BCT-100

Total 15543 results

Bio-Cancer Treatment International Limited

Unknown

Efficacy and Safety Study of Recombinant Human Arginase 1 in Patients With Relapsed or Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia

Hong Kong
Bio-Cancer Treatment International Limited
The University of Hong Kong

Completed

Pegylated Recombinant Human Arginase 1 in Combination With Oxaliplatin and Capecitabine for the Treatment of HCC (PACOX)

Hepatocellular Carcinoma

Hong Kong
University of Birmingham

Completed

A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100) (PARC)

Cancer | Pediatric ALL | Pediatric Solid Tumor | Pediatric AML

United Kingdom, Australia, Netherlands
PhotonMD, Inc

Completed

Modulated Light Therapy in Participants With Pattern Hair Loss

Androgenetic Alopecia

Australia
Bio-Cancer Treatment International Limited
Oncotherapeutics

Completed

Recombinant Human Arginase 1 (rhArg1) in Patients With Advanced Arginine Auxotrophic Solid Tumors

Melanoma | Prostate Adenocarcinoma

United States
Bio-Cancer Treatment International Limited
The University of Hong Kong

Terminated

A Pilot Study of Recombinant Human Arginase 1 (rhArg1) in Patients With Relapsed or Refractory Leukemia or Lymphoma

Lymphoma | Leukemia

China
Bio-Cancer Treatment International Limited
The University of Hong Kong; Chinese University of Hong Kong

Completed

Study of Pegylated Human Recombinant Arginase for Liver Cancer (BCT-100-002) (BCT-100-002)

Hepatocellular Carcinoma | Neoplasm

Hong Kong
Bio-Cancer Treatment International Limited
The University of Hong Kong; Chinese University of Hong Kong

Completed

Efficacy Study of Pegylated Recombinant Human Arginase 1 as a Second-line Therapy in Patients With Advanced Liver Cancer

Hepatocellular Carcinoma

Hong Kong
University of Oxford

Completed

A BCG Challenge Model Study to Assess Anti-mycobacterial Immunity Induced by BCG and a Candidate TB Vaccine, MVA85A

Tuberculosis

United Kingdom
Bio-Cancer Treatment International Limited
The University of Hong Kong; Chinese University of Hong Kong

Completed

Study of Pegylated Human Recombinant Arginase for Liver Cancer

Hepatocellular Carcinoma | Neoplasm

Hong Kong
Apollomics Inc.

Recruiting

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors (SPARTA)

Gastric Cancer | Pancreatic Cancer | NSCLC | Lung Cancer | Brain Tumor | Glioblastoma Multiforme | Advanced Cancer | Colon Cancer | Solid Tumors | Thyroid Cancer | Renal Cancer | Gastroesophageal Junction Adenocarcinoma | EGFR Gene Mutation | MET Amplification | HGF | MET Alteration | MET Fusion | Exon 14 Skipping

United States, Spain, France, United Kingdom, Taiwan, Australia, Finland, Italy, Singapore, Hungary, Canada, Puerto Rico, Russian Federation
Boston Children's Hospital
United States Department of Defense; National Football League

Completed

LED Therapy for the Treatment of Concussive Brain Injury

Brain Concussion

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Assess the Tolerability, Safety, Pharmacodynamics, and Pharmacokinetics of Ascending Single Doses (Including Food Interaction) and Ascending Multiple Doses of ACT-453859, and Multiple Doses of Setipiprant (ACT-129968)

Healthy
Idorsia Pharmaceuticals Ltd.

Completed

Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-389949

Healthy Subjects

Netherlands
Idorsia Pharmaceuticals Ltd.

Terminated

A Study in Healthy Subjects to Investigate the Safety and Tolerability of ACT- 541478 as Well as What ACT-541478 Does to the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-541478

Healthy

Germany
Nielsen Fernandez-Becker
Protagonist Therapeutics, Inc.

Completed

PTG-100 for Patients With Celiac Disease

Celiac Disease

United States
Biocad

Recruiting

A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-PD-1 Compared to Anti-PD-1 Monotherapy as First-Line Treatment in Subjects With Unresectable/Metastatic Melanoma (OCTAVA)

Melanoma | Melanoma (Skin) | Melanoma Stage IV | Melanoma Stage III | Melanoma Metastatic | Melanoma Unresectable | Melanoma Advanced

India, Russian Federation, Belarus
Biocad

Active, not recruiting

Study of Efficacy and Safety of BCD-217 (Anti-CTLA-4 and Anti-PD-1) Followed By BCD-100 (Anti-PD-1) Versus BCD-100 Monotherapy as First-Line Treatment in Patients With Unresectable or Metastatic Melanoma (OBERTON)

Melanoma | Melanoma Metastatic

Russian Federation, Belarus
Biocad

Unknown

International Trial of the Efficacy and Safety of BCD-100 in Patients With Melanoma (MIRACULUM)

Melanoma

Russian Federation
Biocad

Unknown

A Multicenter Open-Label Single-Arm Multi-Cohort Phase I Study of BCD-100 in Patients With Advanced Solid Tumors

Melanoma | Renal Cell Carcinoma | Lung Cancer

Russian Federation
Karolinska Institutet
Linkoeping University; Stockholm University

Completed

RCT of Internet-Delivered CBT Treatments for Pathological Gambling: Comparing the Effects of Added Involvement From CSOs

Gambling

Sweden
Yonsei University

Completed

Lower Femtosecond Laser Energy Levels Lead to Better Visual Recovery After Small-incision Lenticule Extraction for Myopia

Myopia

Korea, Republic of
EuBiologics Co.,Ltd

Completed

Efficacy and Safety of Botulinum Toxin at Moderate to Severe Glabellar Lines

Glabellar Frown Lines

Korea, Republic of
Assistance Publique - Hôpitaux de Paris

Completed

Vitamin D Supplementation in Systemic Lupus Erythematosus (VITALUP)

Vitamin D Deficiency

France
Conceptra Biosciences, LLC

Recruiting

CCT-102 vs. Expectant Management in Delayed Pregnancy Loss (MERMAID)

Early Pregnancy Loss, Delayed Pregnancy Loss

United States
Gonzalez-Heydrich, Joseph, M.D.

Unknown

Anger Control Therapy (ACT) With RAGE-Control: An Outpatient Videogame-assisted Therapy for the Treatment of Anger

Anger | Aggression

United States
Sichuan University
Afﬁliated Hospital of North Sichuan Medical College; Affiliated Hospital of...

Completed

Effect of Lactulose and/or Polyethylene Glycol Solution for Bowel Preparation for Colonscopy Procedures

Colonoscopy

China
Wake Forest University Health Sciences
Medtronic

Recruiting

Esophagogastric Junction Distensibility During Hiatal Hernia Repair

Hiatal Hernia | Esophagogastric Junction Distensibility

United States
Centocor Ortho Biotech Services, L.L.C.

Completed

A Study of Human Rhinovirus Type 16 (HRV-16) Following Administration in the Nose of Healthy Adult Volunteers

Healthy

United States
Hospices Civils de Lyon
GlaxoSmithKline

Recruiting

Symptoms Control and adhErenCe Assessment During Treatment With MepolizUmab New pREfilled Devices (SECURE)

Asthma

France
Transposon Therapeutics, Inc.

Active, not recruiting

A Phase 2a Study of TPN-101 in Patients With Progressive Supranuclear Palsy (PSP)

Progressive Supranuclear Palsy

United States
Region Skane
Karolinska Institutet; Lund University; Region Stockholm

Recruiting

Treatment of Post-covid Syndrome in Patients Treated in Intensive Care

COVID-19 | Mental Health Disorder

Sweden
Catholic University of the Sacred Heart

Completed

STRATOB: a Randomized Controlled Clinical Trial of Cognitive Behavioural Therapy and Brief Strategic Therapy With Telecare for Binge-eating Disorder (STRATOB)

Obesity | Binge Eating Disorder
Skye Bioscience, Inc.

Completed

Phase 2, Placebo-Controlled, Study Assessing the Safety and Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Patients With Elevated Eye Pressure

Primary Open Angle Glaucoma | Ocular Hypertension

United States
Chinese University of Hong Kong

Recruiting

CBT-I Versus CBT-I+ACT for Youths With Insomnia and Anxiety

Insomnia | Anxiety | Youth

Hong Kong
University of Alberta
Canadian Institutes of Health Research (CIHR); AHS Cancer Control Alberta

Completed

The PAC Study: Parents as Agents of Change in Pediatric Weight Management (PAC)

Obesity | Child

Canada
SleepUp Tecnologia em Saúde Ltda

Recruiting

Actigraphy, Wearable EEG Band and Smartphone for Sleep Staging

Insomnia | Sleep

Brazil
Midnight Pharma, LLC

Completed

Almorexant (ACT-078573) in Elderly Subjects With Chronic Primary Insomnia

Chronic Primary Insomnia

United States
Fred Hutchinson Cancer Center
University of Washington

Completed

Innovative Smartphone Application of a New Behavioral Method to Quit Smoking: Pilot Trial (Smart Quit)

Smoking

United States
Merck Sharp & Dohme LLC

Completed

A Study of the Pharmacokinetics of Two Formulations of MK-1006 (MK-1006-010 AM1)(COMPLETED)

Type 2 Diabetes
Memorial Sloan Kettering Cancer Center

Active, not recruiting

PET Imaging of Patients With Melanoma and Malignant Brain Tumors Using an 124I-labeled cRGDY Silica Nanomolecular Particle Tracer: A Microdosing Study

Newly Diagnosed or Recurrent Metastatic Melanoma Patients | Malignant Brain Tumors

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of ACT-1004-1239 in Healthy Male Subjects

Healthy

United States
Accriva Diagnostics

Unknown

Clinical Performance of the Investigational GEM Hemochron® 100 in Populations Ages 18 Years and Older

Blood Coagulation Test

United States
Nova Scotia Health Authority

Completed

Comparing a Group-based Guided Self-help Approach to Pure Self-help for the Treatment of BED

Binge Eating Disorder

Canada
Dartmouth-Hitchcock Medical Center
National Institute on Drug Abuse (NIDA)

Completed

Treatment for Adolescent Marijuana Abuse

Marijuana Abuse

United States
Idorsia Pharmaceuticals Ltd.

Completed

Study in Healthy Subjects to Examine the Safety and Tolerability of ACT-1004-1239 Given as Multiple, Gradually Increasing Doses and to Examine the Effects of ACT-1004-1239 on the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-1004-1239

Healthy

Portugal
BlueWillow Biologics
Porton Biopharma Ltd.

Completed

A Safety and Immunogenicity of Intranasal Nanoemulsion Adjuvanted Recombinant Anthrax Vaccine in Healthy Adults (IN NE-rPA)

Anthrax

United States
University of Sao Paulo

Unknown

Use of Estriol at Distal Third of Vagina Improving Coital Pain in Post-menopause Women

Sexual Dysfunction | Menopause | Dyspareunia

Brazil
University of North Carolina, Chapel Hill
National Institute of Mental Health (NIMH)

Completed

UCAN2: Uniting Couples in the Treatment of Anorexia Nervosa (UCAN2)

Anorexia Nervosa

United States
Sunovion Respiratory Development Inc.

Completed

A Study of the Efficacy and Safety of EP-101 ( (SUN101) in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease (GOLDEN-2)

COPD

United States

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