Search clinical trials for: PF-05190457

Total 1300 results

Pfizer

Completed

Multiple Dose Safety Toelrability, Pharmacokinetics and Midazolam Interaction In Healthy Overweight And Obese Subjects

Glucose Metabolism Disorders | Diabetes Mellitus, Type 2 | Diabetes Mellitus

United States
Pfizer

Completed

The Effect Of PF-03654764 +/- Allegra On Symptoms Of Allergic Rhinitis

Allergic Rhinitis

Canada
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Paclitaxel Plus Trastuzumab in Treating Women With Palpable Breast Cancer That Can Be Removed by Surgery

Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | HER2/Neu Positive

United States, Puerto Rico
Pfizer

Recruiting

A Study to Learn How Different Amounts of the Study Medicine Called PF-07976016 Are Tolerated and Act in The Body in Healthy Adults

Healthy

United States
Pfizer

Completed

Study to Estimate the Effects of Hepatic Impairment on the Pharmacokinetics (PK) of PF-07321332

Hepatic Impairment

United States
Biogen

Completed

A Study To Examine The Effects Of PF-04958242 On Ketamine-Induced Cognitive Impairment In Healthy Volunteers

Schizophrenia

United States
Pfizer

Completed

A Phase 1 Study To Characterize The Safety, Tolerability, PK And PK Of Repeat Doses Of PF-06648671 In Healthy Adults And Healthy Elderly Subjects

Healthy Adult Subjects and Healthy Elderly Subjects

Belgium
Pfizer

Completed

A Study To Test The Safety, Amount And Effects Of PF-06282999 In Healthy Overweight Adults And A Study To Test The Effects Of PF-06282999 On The Amount Of The Approved Drug, Midazolam, In Healthy Adults (B521MAD)

Healthy

Belgium
Pfizer

Completed

A Blinded Study To Examine The Ability Of PF-610,355 To Open The Airways In Asthmatic Patients.

Asthma

United Kingdom, Germany, Sweden
University of Florida

Completed

Effectiveness and Safety of Timolol and Dorzolamide Loaded Contact Lenses

Glaucoma

United States
M.D. Anderson Cancer Center

Terminated

Pazopanib or Pemetrexed and Crizotinib in Advanced Cancer

Advanced Cancers

United States
Pfizer

Completed

A Study To Investigate Whether PF-04457845 Is Effective In Treating Pain, Is Safe And Tolerable In Patients With Osteoarthritis Of The Knee

Osteoarthritis, Knee

United States, Canada, Sweden
National Eye Institute (NEI)

Completed

Triamcinolone Acetonide Plus Laser Therapy to Treat Age-Related Macular Degeneration

Macular Degeneration

United States
Pfizer

Completed

Multiple Dose Safety Tolerability, Pharmacokinetics And Midazolam Interaction In Healthy Overweight And Obese Subjects

Diabetes Mellitus Type 2

United States
Pfizer

Completed

Study To Evaluate The Effect Of Renal Impairment On The Pharmacokinetics Of PF-04991532

Healthy | Type 2 Diabetes Mellitus

United States
Pfizer

Completed

A Study To Assess The Effect Of PF-03893787 On Lung Function Following An Allergen Challenge In Asthmatic Subjects

Asthma

United Kingdom
Pfizer

Recruiting

A Study to Learn About the Study Medicine (Nirmatrelvir Plus Ritonavir) in Pregnant Women With COVID-19

COVID-19

United States
Matrix Biomed, Inc.
Prostate Oncology Specialists

Not yet recruiting

MBM-02 (Tempol) for the Treatment of Biochemical Recurrent Prostate Cancer

Prostate Cancer Recurrent | Biochemical Recurrent Prostate Cancer

United States
Pfizer

Completed

A Study to Learn About the Medicine (PF-07321332 or Nirmatrelvir/Ritonavir) in Healthy Lactating Women

Healthy Participants

Belgium
National Institute of Allergy and Infectious Diseases...
Eli Lilly and Company; National Heart, Lung, and Blood Institute (NHLBI); Gla... and other collaborators

Completed

ACTIV-3: Therapeutics for Inpatients With COVID-19 (TICO)

Covid19

United States, Denmark, Greece, Nigeria, Poland, Singapore, Spain, Switzerland, Uganda, United Kingdom
Pfizer

Terminated

Evaluation of Protease Inhibition for COVID-19 in Standard-Risk Patients (EPIC-SR).

COVID-19

United States, Malaysia, Thailand, Turkey, Spain, Czechia, Poland, Bulgaria, Japan, Korea, Republic of, South Africa, Hungary, Argentina, Brazil, Colombia, Mexico, Puerto Rico, Romania, Slovakia, Ukraine
Pfizer

Terminated

A BRIDGING STUDY OF PF-06439535 (CN) PLUS PACLITAXEL-CARBOPLATIN VERSUS BEVACIZUMAB PLUS PACLITAXEL-CARBOPLATIN IN NSCLC

Advanced Non-squamous NSCLC

China
Pfizer

Completed

A Study To Evaluate The Safety And Tolerability Of Different Doses Of PF-03049423 In Healthy Adult Volunteers And Healthy Older Volunteers

Healthy

Belgium
Pfizer
PPD

Completed

A First In Human Study Of PF-00184562 In Healthy Volunteers

Schizophrenia

United States
Pfizer

Completed

Drug-Drug Interaction Study Assessing Effect of Carbamazepine on PF-07321332 Boosted With Ritonavir

Healthy Participant

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Lenalidomide in Combination With Rituximab in Treating Participants With Stage III/IV Indolent Non-Hodgkin Lymphoma

Ann Arbor Stage III Grade 1 Follicular Lymphoma | Ann Arbor Stage III Grade 2 Follicular Lymphoma | Ann Arbor Stage III Indolent Adult Non-Hodgkin Lymphoma | Ann Arbor Stage IV Grade 1 Follicular Lymphoma | Ann Arbor Stage IV Grade 2 Follicular Lymphoma | Ann Arbor Stage IV Indolent Adult Non-Hodgkin... and other conditions

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) for Recurrent, Metastatic, or Unresectable HER2-Positive Salivary Gland Cancer

Recurrent Salivary Gland Carcinoma | Stage III Major Salivary Gland Cancer AJCC v8 | Stage IV Major Salivary Gland Cancer AJCC v8 | Metastatic Salivary Gland Carcinoma | Unresectable Salivary Gland Carcinoma

United States
Pfizer

Terminated

A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement

Carcinoma, Non-Small-Cell Lung | Brain Neoplasms | Malignant Melanoma | Brain Neoplasms, Primary | Malignant Neoplasms

United States, Canada, Israel
Pfizer

Completed

Food Effect Study to Evaluate the Effect of High-Fat Meal on the Relative Bioavailability of PF-07321332 Boosted With Ritonavir in Healthy Adult Participants

Healthy Participants

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

A Study to Evaluate the Efficacy and Safety of Ertugliflozin in Asian Participants With Type 2 Diabetes and Inadequate Glycemic Control on Metformin Monotherapy (MK-8835-012)

Type 2 Diabetes Mellitus
Pfizer

Terminated

Effects Of PF-02545920 On Ketamine-Induced Abnormal Prefrontal Brain Response To Associative Learning In Healthy Subjects

Healthy

United States
Pfizer

Completed

A Single Dose Study In Japanese And Western Healthy Subjects To Investigate The Safety, Tolerability And Pharmacokinetics Of PF-04991532

Glucose Metabolism Disorders | Diabetes Mellitus, Type 2 | Diabetes Mellitus

United States
Pfizer

Recruiting

A Study to Understand the Effect of Multiple Ascending Doses of PF-07293893 in Healthy Adult Participants

Healthy Participants

Belgium, United States
Shanghai Chest Hospital

Not yet recruiting

Salvage Immunotherapy and Chemotherapy in Esophageal Squamous Cell Carcinoma Patients Nonresponding to Initial Neoadjuvant Chemoradiotherapy (SINCERE)

Esophageal Squamous Cell Carcinomas
Pfizer
Arvinas Estrogen Receptor, Inc.

Completed

A Study to Learn If the Study Medicine Called Vepdegestrant Changes How the Body Processes the Other Study Medicine Called Midazolam

Healthy Participants

Belgium
Qlaris Bio, Inc.

Completed

A Study to Evaluate Safety and Tolerability of QLS-101 in NTG

Normal Tension Glaucoma (NTG)

United States
Pfizer

Completed

The Study is to Evaluate the Effect of Multiple Doses PF-06751979 on the Pharmacokinetics of Midazolam in Healthy Adults

Healthy

Belgium
Baptist Health South Florida
Miami Cancer Institute; Cantex Pharmaceuticals Inc.

Recruiting

Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases (ADORATION)

Cancer | Metastatic Cancer | Metastasis | Brain Metastases | Brain Metastases, Adult

United States
Pfizer

Completed

RN624 In Adult Patients With Chronic Low Back Pain

Low Back Pain

United States
Aristotle University Of Thessaloniki

Completed

24-hour Efficacy and Ocular Surface With Talfuprost and Triple Combined Therapy

Glaucoma | Ocular Surface Disease
Pfizer

Completed

PF-06372865 in Subjects With Photosensitive Epilepsy

Reflex Epilepsy, Photosensitive

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Completed

Vorinostat, Cladribine, and Rituximab in Treating Patients With Mantle Cell Lymphoma, Relapsed Chronic Lymphocytic Leukemia, or Relapsed B Cell Non-Hodgkin's Lymphoma

Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Chronic Lymphocytic Leukemia | Recurrent Indolent Adult Non-Hodgkin Lymphoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Brain | Metastatic Breast Carcinoma

United States
Pfizer

Completed

A Study Of PF-04449913 In Japanese Patients With Select Hematologic Malignancies

Acute Myeloid Leukemia

Japan
Pfizer

Completed

A Study To Estimate The Effect of PF-06650833 On The Pharmacokinetics (PK) of Oral Contraceptive (OC)

Healthy

United States
Pfizer

Completed

A Study To Evaluate PF-04449913 With Chemotherapy In Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia

United States, Spain, Germany, Italy, Poland, Canada
Biogen

Completed

A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of PF-04958242 in Healthy Subjects

Healthy

United States
Pfizer

Terminated

Ph1b/2 Study of PF-04136309 in Combination With Gem/Nab-P in First-line Metastatic Pancreatic Patients (CCR2i)

Metastatic Pancreatic Ductal Adenocarcinoma

United States
Pfizer
Academic GI Cancer Consortium (AGICC)

Terminated

Study Of PF-03084014 In Combination With Gemcitabine And Nab-Paclitaxel In Patients With Metastatic Pancreatic Adenocarcinoma Not Previously Treated With Anticancer Therapies

Metastatic Cancer Pancreas

United States
Pfizer

Completed

An Open-Label, 2 Treatment Period,Study To Study The Drug Interaction Between Repeated Doses Of Itraconazole And Single Dose Pharmacokinetics (PK) Of PF-06648671 In Healthy Adults.

Healthy

United States

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