Search clinical trials for: PF-06821497 Treatment F

Total 118 results

Pfizer

Completed

A Study to Understand the Effect of Tablet Formulation and Food on PF-06821497 in Healthy Adult Participants.

Healthy

United States
Pfizer

Not yet recruiting

A Study to Learn How the Medicine Called [14C] PF-06821497 is Taken up Into and Removed From the Body.

Healthy Participants
Pfizer

Recruiting

PF-06821497 Treatment Of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

Small Cell Lung Cancer (SCLC) | Follicular Lymphoma (FL) | Castration Resistant Prostate Cancer (CRPC)

United States, Spain, Korea, Republic of, Poland, China, Bulgaria, Russian Federation, Japan
Pfizer

Completed

A Study to Understand the Effect of Low-Fat and High-Fat Meals on the Medicine Called PF-07284890 in Healthy Adults

Healthy Participants

United States
Pfizer

Completed

A Study To Assess The Safety Of PF-06342674 In Healthy Volunteers

Healthy

United States
Fundación Garcia Cugat

Completed

Focused Shockwave Treatment in the Recovery Process of Acute Muscle Injuries in Soccer Players

Muscle Injury

Spain
Chiesi Farmaceutici S.p.A.

Completed

PK Linearity and Steady State PK of CHF 6532 in Healthy Subjects

Asthma

Belgium
Florida State University

Completed

False Safety Behavior Elimination Therapy: A Randomized Study of a Brief Individual Transdiagnostic Treatment for Anxiety Disorders

Generalized Anxiety Disorder | Social Anxiety Disorder | Panic Disorder

United States
Pfizer

Completed

This Study Is To Estimate The Time Course Of Pf-04764793 In The Blood Following Dosing By Oral Inhalation From Dry Powder Inhalers

Healthy

Singapore
Pfizer

Completed

A Study To Estimate The Time Course Of PF-00241939 Concentration In The Blood After Dosing With Oral Inhalation From Dry Powder Inhalers

Pharmacokinetics

Singapore
Quark Pharmaceuticals
Pfizer

Terminated

Study Evaluating Efficacy and Safety of PF-04523655 Versus Laser in Subjects With Diabetic Macular Edema (DEGAS)

Diabetes Complications | Diabetic Retinopathy

United States, United Kingdom, Italy, Israel, Germany, Peru, Denmark, India
Johnson & Johnson Consumer Inc. (J&JCI)

Completed

A Study to Evaluate the Efficacy of Investigational OTC Eye Drops

Ophthalmic Solutions

United States
ViiV Healthcare
GlaxoSmithKline; Pharmaceutical Product Development (PPD), Inc

Completed

To Assess the Relative Bioavailability (BA) of TRIUMEQ® and Dolutegravir and Lamivudine (DTG/3TC) Pediatric Dispersible Tablet Formulations in Healthy Volunteers

HIV Infections

United States
Tibotec BVBA

Completed

A Study to Determine the Relative Oral Bioavailability of Single Dose Administration of TMC207, Under Fed and Fasted Conditions in Healthy Participants

Healthy
AstraZeneca
Parexel

Completed

Study to Assess the Bioavailability of Different Formulations of AZD9977 and Dapagliflozin and Influence of Food in Selected Formulations in Healthy Volunteers

Heart Failure

Germany
Pfizer

Completed

Evaluate Taste and Relative Bioavailability of Two Microsphere Formulations of Crizotinib in Healthy Participants

Healthy Volunteers

United States
Pfizer

Completed

A Study to Investigate the Effect of Tablet Formulation and Food on PF-07104091 in Healthy Participants

Healthy

United States
Gilead Sciences

Completed

A Phase 1 Study of Novel GS-9973 Tablet Formulations to Evaluate the Effect of Acid Reducing Agents, Relative Bioavailability, and Food Effect on GS-9973 Pharmacokinetics

Chronic Lymphocytic Leukemia

United States
Merck Sharp & Dohme LLC

Completed

Safety, Pharmacodynamics, and Pharmacokinetics of Different Dosing Regimens of MK-8266 in Participants With Hypertension (MK-8266-008)

Hypertension
Biogen

Terminated

A Study To Evaluate The Safety And Efficacy Of PF-04958242 In Subjects With Cognitive Impairment Associated With Schizophrenia (CIAS)

Cognitive Impairment Associated With Schizophrenia (CIAS)

United States
Tel Aviv University

Completed

F-CaST for Individuals With Substance Use Disorder (F-CaST)

Substance Use Disorders

Israel
Janssen Research & Development, LLC

Completed

A Crossover Study to Evaluate the Bioavailability of Ibrutinib Suspension and Sprinkle Formulations Compared to Capsules in Healthy Adults

Healthy

Belgium
Pfizer

Completed

A Study in Normal Healthy People, Testing Different Versions of a Pill That Will be Used to Treat Rheumatoid Arthritis.

Rheumatoid Arthritis | Healthy Volunteers

United States
Janssen Sciences Ireland UC

Completed

A Crossover Study to Evaluate Relative Bioavailability of Simeprevir Age-appropriate Oral Formulation Candidates Compared With 150-milligram (mg) Oral Capsule in Healthy Adult Participants

Healthy

United Kingdom
Administracion Nacional de Laboratorios e Institutos...

Recruiting

Safety and Effectiveness of an Immunobiological Drug in CoViD-19 (INPB001)

Covid19 | COVID-19 Pneumonia | COVID-19 Respiratory Infection

Argentina
Pfizer
Arvinas Estrogen Receptor, Inc.

Recruiting

A Study to Learn How Various Tablets of the Study Medicine Vepdegestrant Are Taken up Into the Blood of Healthy Adults

Healthy

United States
University Hospital, Strasbourg, France

Recruiting

Effect of Postprandial Insulin Administration of Faster-acting Insulin Analogue Versus Pre-prandial Administration of Acting-insulin Analogue in Cystic Fibrosis Related Diabetes (MIRE)

Cystic Fibrosis-related Diabetes

France
Pfizer

Completed

A Hepatic Impairment Study for PF-04965842.

Hepatic Impairment

United States
Genzyme, a Sanofi Company

Completed

A Study of the Safety and Efficacy of Synvisc in Patients With Symptomatic Shoulder Osteoarthritis

Musculoskeletal Diseases | Osteoarthritis

France, Germany
Assiut University

Completed

A Randomized Controlled Trial Comparing Urea Loaded Nanoparticles to Placebo: a New Concept for Cataract Management

Drug Action Increased
Pearl Network
National Institute of Dental and Craniofacial Research (NIDCR)

Completed

Noncarious Cervical Lesion Treatment Outcomes

Noncarious Cervical Lesions

United States
Boehringer Ingelheim

Completed

Effectiveness and Safety of Synvisc® Versus Usual Treatments in Patients With Knee Osteoarthritis

Osteoarthritis
Case Comprehensive Cancer Center

Completed

Feasibility of a Team Approach for Discussing Prognosis and Treatment Goals in Breast Cancer

Advanced Breast Cancer | Recurrent Breast Cancer | Stage 4 Breast Cancer

United States
Cancer Trials Ireland

Terminated

Positron Emission Tomography and Computed Tomography in Planning Treatment for Patients Undergoing 3-Dimensional Conformal Radiation Therapy for Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery. ICORG 06-35

Lung Cancer | Metastatic Cancer

Ireland
Indiana University
HALEON

Completed

In Situ Comparison of the Remineralization Potential of Optimized Fluoride Dentifrice With Control Fluoride Dentifrice

Caries

United States
Hospices Civils de Lyon

Recruiting

Evaluation of a Management Strategy for Second-degree Fibrinous Burns Integrating a Poly-absorbent Dressing (HYDRA-B)

Burns Degree Second

France
Pfizer

Completed

Study To Assess The Bioequivalence Under Fed And Fasted Conditions Of The Fesoterodine Beads-In-Capsule SR4 And SR7 Formulations And To Estimate The Bioavailability of SR7 Beads Sprinkled On Apple Sauce Relative To The Beads-In-Capsule SR7 Formulation Administer

Neurogenic Detrusor Overactivity

Belgium
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

OX40, Venetoclax, Avelumab, Glasdegib, Gemtuzumab Ozogamicin, and Azacitidine in Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia

United States
Pfizer

Completed

Multiple Dose Study of PF-04991532 in Patients With Type 2 Diabetes

Glucose Metabolism Disorders | Diabetes Mellitus, Type 2 | Diabetes Mellitus

United States
Pfizer

Completed

Estimation of the Effect of Multiple Dose Ritlecitinib (PF-06651600) on the Pharmacokinetics of a Single Dose of Caffeine in Healthy Participants

Healthy Participants

United States
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Electrophysiological Effects of Potential QT Prolonging Drugs

Pharmacokinetics | Pharmacodynamics | Drug-induced QT Prolongation

United States
Charleston Laboratories, Inc

Completed

A Controlled Study to Determine the Efficacy and Safety of CL-108 5 mg for Acute Pain and the Prevention of OINV

Pain | Nausea | Vomiting

United States
Pfizer

Completed

The Effect Of PF-03654764 +/- Allegra On Symptoms Of Allergic Rhinitis

Allergic Rhinitis

Canada
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Myxopapillary Ependymoma | Adult Oligodendroglioma | Adult Pilocytic... and other conditions

United States
University of Washington
National Cancer Institute (NCI)

Completed

FLT PET in Measuring Treatment Response in Patients With Newly Diagnosed Estrogen Receptor-Positive, HER2-Negative Stage I-III Breast Cancer

Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Positive | HER2/Neu Negative | Male Breast Carcinoma

United States
Pfizer

Completed

A Study to Determine the Effects of PF-04965842 on Midazolam PK in Healthy Volunteers

Phase 1

Belgium
Zeng Changhao

Recruiting

Stellate Ganglion Block in Obstructive Sleep Apnea

Obstructive Sleep Apnea

Taiwan
Pfizer

Completed

Drug Interaction Study Evaluating the Effect of Rifampin on PK and Safety of PF 04965842.

Healthy

Belgium
Thammasat University

Active, not recruiting

Comparing Intra-articular Betamethasone (Diprospan) and Triamcinolone Acetonide Injection in Knee Osteoarthritis

Knee Osteoarthritis

Thailand
Mayo Clinic
National Cancer Institute (NCI)

Suspended

Direct Tumor Microinjection and FDG-PET in Testing Drug Sensitivity in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma, Hodgkin Lymphoma, or Stage IV Breast Cancer

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Recurrent Non-Hodgkin Lymphoma | Refractory Non-Hodgkin Lymphoma | Recurrent Breast Carcinoma | Recurrent Mycosis Fungoides | Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma | Stage IV Breast Cancer AJCC v6 and v7 | Breast Adenocarcinoma and other conditions

United States

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