Search clinical trials for: PF-06863135

Total 1293 results

Pfizer

Completed

A First-in-human Study of Single Doses of PF-07328948 Which is Given to Healthy Adult Participants

Healthy

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Safety and Efficacy of a FAAH-Inhibitor to Treat Cannabis Withdrawal

Cannabis Dependence

United States
Pfizer

Completed

Study of Multiple Oral Doses of PF-06835919 in Healthy Adult Japanese Participants

Healthy

Belgium
Pfizer

Terminated

A Phase 2 Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of PF-06252616 in Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

United States, Australia, Canada, United Kingdom, Japan, Bulgaria, Italy, Poland
University of Zurich
Pfizer

Completed

Effects of PF-06412562 on Value-based Decision-making in Healthy Individuals

Decision Making

Switzerland
Pfizer

Completed

Study of Single Ascending Doses of PF-07081532 in Healthy Adult Participants

Healthy

Belgium
Pfizer

Completed

Singe Dose Study of PF- 06946860 in Healthy Adult Japanese Participants

Healthy

United States
Biogen

Completed

First-in-Human Study of PF-04958242 in Healthy Volunteers

Healthy Volunteer

Singapore
Pfizer

Terminated

An Evaluation Of PF-03715455 In Moderate To Severe Uncontrolled Asthma

Asthma

United States
Pfizer

Completed

A Study To Assess The Safety, Tolerability, And Pharmacokinetics (PK) Of Multiple Doses Of PF-06865571 In Healthy, Including Overweight And Obese, Adult Subjects

Healthy Subjects

United States, Belgium
Pfizer

Completed

Single Dose of PF-06835919 Escalation Study in Healthy Adult Subjects

Non-alcoholic Fatty Liver Disease

United States
Pfizer

Completed

Safety and Pharmacokinetic Study of PF-06651600 in Japanese Healthy Volunteers

Healthy

Belgium
Pfizer

Completed

Test Re-Test Reliability of [11C]PF-06809247 as a Novel PET Tacer

Neuroinflammation

United States
Pfizer

Completed

A Study To Evaluate the Safety, Tolerability, And Pharmacokinetics Of PF-06266047 In Healthy Adult Subjects

Healthy Volunteers

Belgium
Pfizer

Completed

A Study to Evaluate the Pharmacodynamic Effects of Single Oral Doses of PF-06648671 on β-Amyloid (Aβ) Concentrations in Cerebrospinal Fluid (CSF)

Healthy Subjects

United States
Pfizer

Completed

A Study To Investigate The Absorption, Distribution, Metabolism, And Excretion Of [14c]PF-06463922 In Healthy Male Volunteers

Healthy

United States
University Health Network, Toronto
Pfizer

Completed

Study to Assess Biomarkers in Patients With Resectable Oral Cavity Cancer Randomized to Receive Preoperative Treatment

Oral Cavity Cancer

Canada
Pfizer

Completed

A Study To Understand How Radiolabelled PF-04449913 Is Taken Up By The Body, Broken Down And Then Removed From The Body

Healthy

United States
Pfizer

Withdrawn

Study Of Safety, Tolerability And Effects Of PF-05175157 In Adults With Moderate To Severe Acne Vulgaris

Acne Vulgaris
Pfizer

Completed

A Study to Evaluate Safety, Toleration and Time Course of Plasma Concentration of Multiple Oral Doses of PF-06273340 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) and Aged 56-75 Years (Group 2)

Healthy

Belgium
Pfizer

Completed

Cold Pressor Test is Used in This Study to Assess the Effect of PF-06305591 on Pain Intensity Evoked by Cold in Healthy Male Subjects

Healthy

Belgium
Quark Pharmaceuticals
Pfizer

Completed

Study of PF-04523655 (REDD14NP) In Subjects With Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (Wet AMD)

Age-Related Macular Degeneration

United States, Israel
Pfizer

Completed

PK And Safety Study Of PF-04171327 In Healthy Japanese And Western Subjects In Fasting And Fed Conditions

Healthy

United States
Pfizer

Completed

A First In Human Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Single Inhaled Doses Of PF-05212372.

Pharmacokinetics | Safety | Phase 1 | Single Dose | Toleration

Belgium
Pfizer

Completed

Single Dose Escalation Study of PF-05190457 in Healthy Volunteers

Diabetes Mellitus, Type II

Belgium
Pfizer

Completed

A Phase I, Single Dose Study Of PF-04360365 In Japanese Patients With Mild To Moderate Alzheimer's Disease

Alzheimer's Disease

Japan
Pfizer

Completed

A Study In Healthy People To Investigate The Safety, Toleration And Time Course Of Blood Concentrations Of Multiple Doses Of PF-03654764, Given By Mouth

Healthy

Singapore
Pfizer

Completed

A Study Of Adjunctive Treatment Of Cognitive Deficits In Schizophrenia

Schizophrenia

United States
Pfizer

Completed

Single Dose Lipopolysaccharide (LPS) Study In Healthy Volunteers

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Pfizer

Completed

Multiple Dose Escalation Trial Of PF-04308515 In Healthy Volunteers

Healthy

United States
Yale University
National Institute of Mental Health (NIMH); University of Pennsylvania; Columbia... and other collaborators

Recruiting

A Translational and Neurocomputational Evaluation of a Dopamine Receptor 1 Partial Agonist for Schizophrenia

Early Course Schizophrenia Spectrum Disorder

United States
Pfizer

Completed

Single Dose Study With Unlabeled Dose and 14C-labeled Microdose of PF-06700841 in Healthy Male Subjects

Healthy Male Subjects

Netherlands
Pfizer

Terminated

A First in HumanTrial to Evaluate The Safety, Tolerability, And Pharmacokinetics Of PF-06755347

Healthy | Polyradiculoneuropathy, Chronic Inflammatory Demyelinating | Primary Immune Thrombocytopenia

Spain, United States, Belgium, United Kingdom, New Zealand
Pfizer

Recruiting

A Study to Learn How Different Products of the Study Medicine Called PF-07940367 Are Taken up Into the Blood in Healthy Adults

Healthy

United States
Region Örebro County
Uppsala University Hospital; Rygglkirurgiskt Centrum Stockholm AB; Norrlands...

Recruiting

Örebro Multicenter Study on Operative Treatment of Cervical Radiculopathy (OMSAP)

Cervical Radiculopathy | Cervical Root Compression

Sweden
Moorfields Eye Hospital NHS Foundation Trust
University College, London

Recruiting

A Study Of Implantation Of Retinal Pigment Epithelium In Subjects With Acute Wet Age Related Macular Degeneration

Age Related Macular Degeneration

United Kingdom
Pfizer

Completed

A Study To Evaluate The Pharmacokinetics, Excretion, Mass Balance and Metabolism of PF-07265803

Healthy

United States
Pfizer

Completed

A Study Of PF-04449913 Administered Alone In Select Solid Tumors

Solid Tumors

United States
Pfizer

Completed

PF-04634817 Renal Impairment Study

Renal Insufficiency

United States
Pfizer

Terminated

A Clinical Trial of the Study Medicine (PF-07081532) in People With Diabetes and Kidney Dysfunction

Renal Impairment | Type 2 Diabetes

United States
Telavant, Inc.
Pfizer

Completed

Safety, Efficacy, and Tolerability Study of PF-06480605 in Subjects With Moderate to Severe Ulcerative Colitis.

Colitis, Ulcerative

United States, Korea, Republic of, Belgium, Italy, Netherlands, Poland
Pfizer

Completed

Study to Evaluate Safety and Tolerability of a Single Dose of PF-06741086 in Chinese Adult Participants With Severe Hemophilia

Severe Hemophilia

China
Pfizer

Completed

A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors

NSCLC | SCCHN | Part 1 | MELANOMA | OVCA | SARCOMA | OTHER SOLID TUMORS | Part 1 and 2 | UROTHELIAL CARCINOMA

United States, Korea, Republic of, Russian Federation, Poland, Malaysia, Bulgaria, Ukraine
Pfizer

Completed

PHARMACOKINETIC CHARACTERIZATION OF PF-06651600 IN CHINESE ADULT PARTICIPANTS

Healthy Participants

China
Pfizer

Completed

Open-Label Trial Of Oral PF-00299804 By Continuous Dosing In Patients With Recurrent Or Metastatic Head And Neck Squamous Cell Cancer

Head and Neck Neoplasms

Canada
Fusion Pharma LLC
Data Matrix Solutions; OCT Rus, LLC; Skolkovo Innovation Center

Unknown

Study to Evaluate Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy of PF-114 for Oral Administration in Adults With Ph+ Chronic Myeloid Leukemia, Which is Resistant to the 2-nd Generation Bcr-Abl Inhibitors or Has T315I Mutation in the BCR-ABL Gene

Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Chronic Myeloid Leukemia

Russian Federation
National Institute on Alcohol Abuse and Alcoholism...
National Center for Advancing Translational Sciences (NCATS); University of...

Completed

A Novel Compound for Alcoholism Treatment

Alcohol Drinking | Alcohol Dependence | Alcoholism | Alcohol-Related Disorders | Alcohol Drinking Related Problems

United States
Pfizer

Completed

PF-06741086 Multiple Dose Study in Severe Hemophilia

Hemophilia A or B

United States, Chile, Croatia, Poland, South Africa, Switzerland
Pfizer

Terminated

A Study Of PF-06647263 In Patients With Advanced Solid Tumors

Neoplasms | Triple-Negative Breast Cancer

United States
Pfizer

Terminated

A Dose Escalation Study of PF-06650808 in Patients With Advanced Solid Tumors

Neoplasms | Breast Cancer

United States

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