Search clinical trials for: PKC412
Total 32 results
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Novartis PharmaceuticalsNo longer availableAcute Myeloid Leukemia (AML) With | FLT3 Mutation, Internal Tandem Duplication (ITD) or Tyrosine Kinase Domain (TKD)United States
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University Medical Center GroningenUnknown
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Novartis PharmaceuticalsAvailableAcute Myeloid Leukemia | Mast Cell Leukemia | Aggressive Systemic Mastocytosis | Systemic Mastocytosis With an Associated Hematologic Neoplasm | FMS-Like Tyrosine Kinase 3 (FLT3)-Mutated Acute Myeloid Leukemia
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Novartis PharmaceuticalsCompletedLeukemiaUnited States, Belgium, Netherlands, Canada, Austria, Germany, Australia, United Kingdom, Turkey, France, Poland, Norway
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Novartis PharmaceuticalsCompletedAcute Myeloid LeukemiaUnited States, Canada
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Jason Robert GotlibNovartis; Novartis PharmaceuticalsCompletedSystemic Mastocytosis, Aggressive (ASM) | Leukemia, Mast Cell | Hematological Non-mast Cell Lineage Disease (AHNMD)United States
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Novartis PharmaceuticalsTerminatedAcute Myeloid Leukemia | Acute Lymphoblastic LeukemiaSweden, Italy, France, United States, Netherlands
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Novartis PharmaceuticalsCompletedAcute Myeloid LeukemiaJapan, Taiwan, Hong Kong, Thailand, Korea, Republic of, Russian Federation, Vietnam
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Technische Universität DresdenNovartis PharmaceuticalsCompletedAcute Myeloid LeukemiaGermany
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Novartis PharmaceuticalsCompletedHepatic ImpairmentGermany, Belgium, Lithuania, United States, Bulgaria, Romania
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Braintree LaboratoriesCompletedColonoscopyUnited States
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Novartis PharmaceuticalsCompletedAcute Myeloid Leukemia (AML)United States, Spain, Belgium, Germany, Japan, Taiwan, Turkey, Italy, Australia, Austria, Switzerland, Israel, Bulgaria, France, Norway, Brazil, Poland, Portugal, Czechia, Argentina
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University of KansasNovartisCompletedAcute Myeloid LeukemiaUnited States
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M.D. Anderson Cancer CenterNovartis Pharmaceuticals; Celgene CorporationCompleted
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Richard Stone, MDMassachusetts General Hospital; Novartis; Beth Israel Deaconess Medical Center; Brigham and Women's HospitalActive, not recruitingRAD001 in Combination With PKC412 in Patients With Relapsed, Refractory or Poor Prognosis AML or MDSAcute Myeloid Leukemia | Myelodysplastic SyndromeUnited States
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University of FloridaNovartis PharmaceuticalsWithdrawnAcute Myeloid LeukemiaUnited States
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David IberriTerminatedAcute Myeloid Leukemia (AML) With Multilineage Dysplasia Following Myelodysplastic Syndrome, in Adults | AML (Adult) With 11q23 (MLL) Abnormalities | AML (Adult) With Del (5q) | AML (Adult) With Inv (16) (p13; q22) | AML (Adult) With t (16;16) (p13; q22) | AML (Adult) With t (8; 21) (q22; q22) and other conditionsUnited States
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Sanwa Kagaku Kenkyusho Co., Ltd.Completed
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University of UlmNovartis PharmaceuticalsCompleted
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Maria de Lourdes de Sousa Maia, MDNot yet recruiting
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Brenda Cooper, MDNational Cancer Institute (NCI)CompletedUntreated Adult Acute Myeloid LeukemiaUnited States
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Novartis PharmaceuticalsCompletedAcute Myeloid Leukemia (AML)United States, Germany
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Mayo ClinicNational Cancer Institute (NCI)TerminatedSecondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Acute Myeloid Leukemia With FLT3/ITD Mutation | Acute Myeloid Leukemia With Gene Mutations | FLT3 Tyrosine Kinase Domain Point MutationUnited States
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Novartis PharmaceuticalsCompletedAcute Myeloid LeukemiaItaly, Croatia, Estonia, Czechia, France, Spain, Sweden, Bulgaria, Lithuania, Serbia, Hungary, Finland, Norway, Romania, Slovakia
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Novartis PharmaceuticalsCompletedAcute Myeloid Leukemia | Myelodysplastic SyndromesUnited States
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Washington University School of MedicineCompletedLeukemia, Myeloid, AcuteUnited States
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Novartis PharmaceuticalsRecruitingFLT3-mutated Acute Myeloid LeukemiaKorea, Republic of, Germany, Italy, Turkey, Czechia, Jordan, Slovenia, Austria, Poland, Japan, Russian Federation, United States, Greece
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Alison WalkerNovartis; Millennium Pharmaceuticals, Inc.CompletedAcute Myeloid Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid... and other conditionsUnited States
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Novartis PharmaceuticalsWithdrawnLeukemia, Myeloid, Acute
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)RecruitingAcute Myeloid Leukemia | Previously Treated Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Myelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive and other conditionsUnited States
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National Cancer Institute (NCI)Active, not recruitingAcute Myeloid Leukemia | Myelodysplastic Syndrome | Myelodysplastic Syndrome/Acute Myeloid LeukemiaUnited States
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Uma BorateRecruiting