Search clinical trials for: PN 400

Total 12388 results

Sunovion

Completed

A Clinical Study to Test the Effectiveness of an Investigational Drug to Treat People That Have Major Depressive Episodes When They Have Bipolar 1 Depression

Depressive Episode | Bipolar 1 Depression

Japan, Serbia, United States, Poland, Russian Federation, Bulgaria, Slovakia, Ukraine
Trius Therapeutics LLC

Completed

Phase 2 Study of TR-701 in Patients With Complicated Skin and Skin Structure Infections

Skin Diseases, Infectious | Skin Diseases, Bacterial

United States
Hoffmann-La Roche

Completed

Safety, Tolerability, and Antiviral Activity of ANA598 in Patients With Genotype-1 Chronic HCV Infection

Chronic Hepatitis C

United States, Puerto Rico
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

First in Human Study of M4344 in Participants With Advanced Solid Tumors

Solid Tumor | Advanced Solid Tumor

Spain, United States, Netherlands, United Kingdom
NeuroBo Pharmaceuticals Inc.

Completed

Pharmacokinetics and Pharmacodynamics Study of Gemcabene in Healthy Volunteers

Hypercholesterolemia
Baxter Healthcare Corporation

Completed

Clinical Performance Comparison of 2 THERANOVA 400 Dialyzer Prototypes in HD With High-Flux Dialyzers in HD and hv HDF Mode

End Stage Renal Disease

Germany
Yuhan Corporation

Completed

The Exploration for Pharmacodynamics and Pharmacokinetics of YH4808 New Formulation in Healthy Subjects

Healthy

Korea, Republic of
University Hospital, Ghent

Completed

Highly Accelerated Dose-Integrated Radiotherapy in 5 Fractions in Breast Cancer (HAI-5)

Breast Cancer | Radiotherapy

Belgium
GlaxoSmithKline
Parexel

Completed

To Investigate the Pharmacokinetics and Safety of Fluticasone Furoate (FF)/ Umeclidinium (UMEC) Combination Compared With FF and UMEC Monotherapies in Adult Healthy Volunteers Using a Dry Powder Inhaler (DPI)

Asthma

United States
N-Gene Research Laboratories, Inc.
Thermo Fisher Scientific, Inc; Integrium; Msource Medical Development GmbH; Kinexum... and other collaborators

Terminated

Safety and Efficacy of BGP-15 in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus

United States, Germany, Hungary
SIGA Technologies
National Institutes of Health (NIH)

Completed

Safety, Tolerability, Pharmacokinetics (PK) of the Anti-Orthopox Drug, ST-246 (246-Safety)

Orthopoxviral Disease

United States
Virginia Commonwealth University
AbbVie

Withdrawn

Venetoclax and Irinotecan in Relapsed/Refractory SCLC

Relapsed Small Cell Lung Cancer | Refractory Small Cell Lung Carcinoma
MacroGenics

Completed

A Study of MGD013 in Patients With Unresectable or Metastatic Neoplasms

Cervical Cancer | Hematologic Neoplasms | Ovarian Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumors | Squamous Cell Carcinoma of Head and Neck | Cholangiocarcinoma | Small-cell Lung Cancer | TNBC - Triple-Negative Breast Cancer | HER2-positive Advanced Solid Tumors

Hong Kong, United States, Thailand, Australia, Spain, Bulgaria, Poland, Ukraine
Berkeley Eye Center

Completed

Assessment of Measurement Variability Across Automated Biometry Devices

Myopia

United States
Dongguan HEC TaiGen Biopharmaceuticals Co., Ltd.
R&G Pharma Studies Co.,Ltd.

Completed

To Evaluate PK and Safety Profile of Oral MAD of Separately Using TG-2349, DAG181 or Combination in Healthy Chinese Volunteers

Healthy Chinese Volunteers

China
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Assess the Tolerability, Safety, Pharmacodynamics, and Pharmacokinetics of Ascending Single Doses (Including Food Interaction) and Ascending Multiple Doses of ACT-453859, and Multiple Doses of Setipiprant (ACT-129968)

Healthy
Emory University
National Institute of Nursing Research (NINR)

Recruiting

Trial of Community-based Patient Navigation

Pregnancy Related

United States
University of Utah
National Institute on Minority Health and Health Disparities (NIMHD); National... and other collaborators

Completed

SCALE-UP Utah II: Community-Academic Partnership to Address COVID-19 Text Message Study

COVID-19

United States
Hiroshima University
Kaneka Corporation

Completed

Effect of Chrysanthemum Flower Oil and Its Dose-dependency on Hyperuricemia

Hyperuricemia

Japan
Egyptian Liver Hospital
Wadi El Nil Hospital

Completed

Randomized, Open-Label, Study to Evaluate the Safety and Efficacy of Sofosbuvir Tablet Plus Ribavirin Tablet (Part A) Versus Single Dose (2 Tablets) of EHCV Containing Sofosbuvir, Ribavirin, and Natural Anti-hemolytic (B) in Egyptian Adults With Chronic Genotype 4 HCV Infection

Hepatitis c

Egypt
University of Cincinnati

Completed

End Stage Liver Disease and Body Composition Assessment: Utilizing Bioelectric Impedance Analysis (BIA)

End Stage Liver Disease

United States
Decathlon SE
EFOR, France

Terminated

Assessment of the Safety and Performance of Ankle Ligament Supports in the Context of a Return to Sport After Sprain

Ankle Sprain 1St Degree | Ankle Sprain 2Nd Degree | Ankle Sprain 3Rd Degree

France
Obafemi Awolowo University
London School of Hygiene and Tropical Medicine; University of California, San... and other collaborators

Completed

Viral and Antiretroviral Dynamics in HIV-1 Mother-to-Child Transmission Fluids (VADICT)

Human Immunodeficiency Virus Infection

Nigeria
GlaxoSmithKline

Completed

Pharmacokinetic Study in Healthy Volunteers to Characterise the Exposure of Fluticasone Furoate (FF), Vilanterol (VI) and Umeclidinium (UMEC) at Two Different Doses

Pulmonary Disease, Chronic Obstructive

United States
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID)

Active, not recruiting

Ultra Curto (Ultra Short) TB Prevention Therapy

Tuberculosis

Brazil
Impax Laboratories, LLC

Completed

Pharmacokinetics and Pharmacodynamics of IPX054 in Subjects With Parkinson's Disease

Idiopathic Parkinson's Disease

United States
Sumitomo Pharma America, Inc.

Terminated

A Clinical Study of an Investigational Drug for the Treatment of Major Depressive Episode Associated With Bipolar I Disorder.

Depressive Episodes, Bipolar I Depression

United States, Bulgaria, Japan, Romania, Canada, Slovakia
Vanderbilt University
National Institute of Environmental Health Sciences (NIEHS)

Completed

Brain Manganese Deposition in High Risk Neonates

Necrotizing Enterocolitis | Cholestasis | Digestive System Abnormalities

United States
Vanderbilt University
The Gerber Foundation

Completed

Neurodevelopment and Neuroimaging in Parenterally-fed Infants and Young Children

Necrotizing Enterocolitis | Cholestasis | Digestive System Abnormalities | Parenteral Nutrition

United States
AstraZeneca

Completed

Safety and Tolerability Study of MEDI0382 in Japanese Preobese or Obese Subjects With Type 2 Diabetes

Type 2 Diabetes

Japan
Global Alliance for TB Drug Development

Completed

A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics of TBI-223 in Healthy Adults

Tuberculosis | Tuberculosis, Pulmonary

United States
Janssen R&D Ireland

Completed

TMC125-TiDP2-C238: An Exploratory Pharmacokinetics, Safety and Anti-HIV Activity Study of Etravirine (ETR) When Given With Boosted Atazanavir (ATV/Rtv) at Two Different Doses and 1 Nucleoside Reverse Transcriptase Inhibitor (NRTI) in Treatment Experienced HIV Patients

HIV Infections | Acquired Immunodeficiency Syndrome

United States, France, Argentina, South Africa, Thailand
Jazz Pharmaceuticals

Completed

Study to Evaluate the Effect of GWP42003 on Liver Fat Levels in Participants With Fatty Liver Disease

Fatty Liver

United Kingdom
RedHill Biopharma Limited

Terminated

Upamostat, a Serine Protease Inhibitor, or Placebo for Treatment of COVID-19 Disease

Covid19

United States, South Africa
Shire

Completed

Safety and Efficacy of NPS 1776 in the Acute Treatment of Migraine Headaches

Migraine Headache

United States
Seoul National University Hospital

Completed

CT Window Setting to Select Double-lumen Tube Size

Bronchial Cuff Volume at Air-tight Seal | Intracuff Cuff Pressure at Air-tighe Seal

Korea, Republic of
Azienda Ospedaliero-Universitaria Careggi
Società Italiana di Urologia (SIU); Italian Group for Advanced Laparo-Endoscopic...

Recruiting

International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors (i-RECORd)

Kidney Cancer

Italy, United States, Spain, United Kingdom, Belgium, Austria, Brazil, Greece, Japan, Netherlands, Poland, Russian Federation, Singapore
National Taiwan University Hospital

Recruiting

Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX) for Patients With Hepatitis C Virus Infection

Hepatitis C Virus Infection | Treatment Side Effects | Effect of Drug | Adherence, Treatment

Taiwan
The Cleveland Clinic
Bristol-Myers Squibb; National Institute of Allergy and Infectious Diseases... and other collaborators

Terminated

Switching From Efavirenz to Atazanavir/ Ritonavir in HIV-infected Subjects With Good Virologic Suppression

HIV Infection | Mitochondrial Dysfunction

United States
Ixchelsis Limited

Completed

IX-01 Effect on Intravaginal Ejaculatory Latency Time (IELT), Patient Reported Outcomes and Safety in Men With Premature Ejaculation (PE)

Premature Ejaculation

United States
Yuhan Corporation

Completed

AME Study of [14C]-YH4808 in Healthy Male Subjects

Healthy

United States
KU Leuven
Baxter Healthcare Corporation; Fund for Scientific Research, Flanders, Belgium

Active, not recruiting

Impact of Early Parenteral Nutrition Completing Enteral Nutrition in Adult Critically Ill Patients (EPaNIC)

Critical Illness | Starvation

Belgium
ViiV Healthcare
GlaxoSmithKline

Terminated

Dose-finding Study of GSK2248761 in Antiretroviral Therapy-Naive Subjects (SIGNET) (SIGNET)

Infection, Human Immunodeficiency Virus

Spain, France, Germany
Boehringer Ingelheim

Completed

Nevirapine vs. Atazanavir Boosted With Ritonavir on a Background of Truvada in Human Immunodeficiency Virus (HIV) Infected Naive Patients (NEwArT)

HIV Infections

United States
Rob Surgical Systems S.L.

Completed

Safety and Performance Assessment of a First Four Arms on Demand Open Robotic Solution for Assisted PN, RN and RP

Nephrectomy | Prostatectomy

Spain
University of Utah
National Institute on Minority Health and Health Disparities (NIMHD); National... and other collaborators

Completed

SCALE-UP Utah II: Community-Academic Partnership to Address COVID-19 Conversational Agent Study

COVID-19

United States
Decathlon SE
EFOR, France

Recruiting

Assessment of the Safety and Performance of a Lumbar Belt

Low Back Pain

France
RespireRx
Duke University

Unknown

Antagonism of Opioid-Induced Respiratory Depression by CX1739 With Preservation of Opioid Analgesia

Opiate Induced Respiratory Depression

United States
Kowa Research Institute, Inc.

Completed

Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of K-312 in Healthy Subjects

Hyperlipidemia

United States
Medicines for Malaria Venture
Q-Pharm Pty Limited; Clinical Network Services (CNS) Pty Ltd; QIMR Berghofer...

Completed

Safety, Tolerability and Antimalarial Activity of Single Doses of OZ439 and PQP

Malaria

Australia

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