Search clinical trials for: PRA023 IV

Total 3227 results

Vanderbilt University

Completed

Effect of Chronic ACE and DPP4 Inhibition on Blood Pressure

Hypertension | Type 2 Diabetes Mellitus

United States
GlaxoSmithKline

Completed

Ability of Four Toothpastes to Remove Plaque

Dental Plaque
University of Athens

Unknown

Effect of Perioperative iv Dexmedetomidine vs. Lidocaine on Postoperative Pain, Analgesic Consumption and Recovery After Abdominal Gynaecological Surgery

Hysterectomy | Myomectomy

Greece
Clinical Research Centre, Malaysia
Ministry of Health, Malaysia

Unknown

Efficacy and Safety of Cholestyramine and Prednisolone as Adjunctive Therapy in Treatment of Overt Hyperthyroidism (ChoPS)

Graves Disease | Hyperthyroidism

Malaysia
UniQure Biopharma B.V.
Chiesi Farmaceutici S.p.A.

Withdrawn

Alipogene Tiparvovec for the Treatment of LPLD Patients

LPL Deficiency

Canada, United States
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety and Efficacy of Sitagliptin 100 mg in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control (MK-0431-229)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Co-Administration of Sitagliptin and Metformin in China (MK-0431-121)

Type 2 Diabetes Mellitus
Institute of Rheumatology, Prague
Karolinska Institutet

Completed

Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With PM and DM (Prometheus)

Dermatomyositis | Polymyositis

Czech Republic
Grifols Therapeutics LLC

Completed

Use of Immune Globulin Intravenous (Human) To Treat Age-Related Macular Degeneration

Macular Degeneration

Germany
Oslo University Hospital

Recruiting

TENecteplase in Central Retinal Artery Occlusion Stuy (TenCRAOS) (TenCRAOS)

Central Retinal Artery Occlusion

Denmark, Norway, Belgium, Sweden, Finland, Ireland, Lithuania, Australia, Austria
Emory University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Oral Anti Diabetic Agents in the Hospital

Diabetes Mellitus

United States
Kallyope Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of K-757 in Healthy Overweight/Obese Volunteers

Obesity

United States
M.H.H. Kramer

Active, not recruiting

Renal Actions of Combined Empagliflozin and LINagliptin in Type 2 diabetES (RACELINES)

Type2 Diabetes

Netherlands
Merck Sharp & Dohme LLC

Completed

A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Concomitant Administration of Sitagliptin and Metformin as Individual Tablets (0431A-048)

Type 2 Diabetes
John DeWitt
American Society for Gastrointestinal Endoscopy; Pinnacle Biologics Inc.

Completed

Ultrasound-Guided Photodynamic Therapy With Photofrin & Gemcitabine for Patients With Locally Advanced Pancreatic Cancer

Acinar Cell Adenocarcinoma of the Pancreas | Duct Cell Adenocarcinoma of the Pancreas | Stage III Pancreatic Cancer

United States
Vanderbilt University

Completed

Effect of DPP4 Inhibition on Vasoconstriction

Type 2 Diabetes Mellitus

United States
Colette Curtis MD

Terminated

Comparison of Exparel to Bupivacaine With Dexamethasone in TAP Block (TapBlock)

Pain

United States
EMS

Terminated

Comparison of Desloratadine Associated With Prednisolone Oral Solution Versus Dexchlorpheniramine Associated With Betamethasone for Cutaneous Rash Treatment

Cutaneous Hypersensitivity

Brazil
Merck Sharp & Dohme LLC

Completed

Bioequivalence Study of Sitagliptin/Metformin Combination Tablet (MK0431A-122)

Type 2 Diabetes
Services Hospital, Lahore

Completed

Comparison of Hypoglycaemic Regimens During Ramadan Fasting in Type 2 Diabetes

Diabetes, Type 2

Pakistan
The University of Texas Health Science Center,...

Unknown

Hyperthermia With Chemotherapy for Locally Advanced or Metastatic Pancreas Cancer (FR-WB-TT)

Pancreatic Neoplasms

United States
Assiut University

Not yet recruiting

Opioid Sparing Analgesia Continuous Intraoperative Infusion of Dexmedetomidine Versus Lidocaine for Laparoscopic Cholecystectomy

Analgesia
Academisch Medisch Centrum - Universiteit van Amsterdam...
Bristol-Myers Squibb

Recruiting

A Study of Mitomycin-c/ Capecitabine ChemoRadiotherapy Combined With Nivolumab Monotherapy or Ipilumimab and Nivolumab, as Bladder Sparing Curative Treatment for Muscle Invasive Bladder Cancer: the CRIMI Study (CRIMI)

Urinary Bladder Cancer | Invasive Bladder Cancer

Netherlands
Angiochem Inc

Not yet recruiting

ANG1005 in Leptomeningeal Disease From Breast Cancer (ANGLeD)

Brain Metastases | Leptomeningeal Metastases | HER2-negative Breast Cancer | Leptomeningeal Carcinomatosis
Ondokuz Mayıs University

Completed

M-Tapa Block vs External Oblique Intercostal Block for Laparoscopic Sleeve Gastrectomy Surgery

Postoperative Pain | Anesthesia | Regional Anesthesia

Turkey
Nantes University Hospital

Completed

A Phase III Randomized, Blind, Double Dummy, Multicenter Study Assessing the Efficacy and Safety of IV THrombolysis (Alteplase) in Patients With acutE Central retInal Artery Occlusion (THEIA)

Central Retinal Artery Occlusion

France
Naestved Hospital

Completed

Effect of Combinations of Paracetamol, Ibuprofen, and Dexamethasone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty (RECIPE)

Postoperative Pain | Analgesia | Pain, Acute | Hip Arthropathy

Denmark
Zagazig University

Completed

Opioid Sparing Analgesia: Dexmedetomidine Versus Lidocaine for Intracranial Surgeries in Children

Analgesia

Egypt
Hoffmann-La Roche

Completed

A Study to Assess the Safety and Tolerability of Atezolizumab in Combination With Other Immune-Modulating Therapies in Participants With Locally Advanced or Metastatic Solid Tumors

Solid Cancers

United States, Netherlands
Sheikh Zayed Federal Postgraduate Medical Institute

Completed

Effect of Apple Cider Vinegar in Type 2 Diabetics

Diabetes Mellitus | Randomized Controlled Trial

Pakistan
Sun Yat-sen University

Completed

Efficacy Study of Liraglutide vs.Sitagliptin vs. Glargine on Liver Fat in T2DM Subjects (LIGHT-ON)

Non-alcoholic Fatty Liver Disease

China
Hadassah Medical Organization

Unknown

Treatment of Wolfram Syndrome Type 2 With the Chelator Deferiprone and Incretin Based Therapy

Diabetes Mellitus | Iron Metabolism Disorders | Optic Atrophy | Sensorineural Hearing Loss | Platelet Dysfunction | Gastroduodenal Ulcer

Israel
EMS

Completed

Comparison of Desloratadine Associated With Prednisolone Oral Solution Versus Dexchlorpheniramine Associated With Betamethasone for Persistent Allergic Rhinitis Treatment

Allergic Rhinitis
Zalicus

Completed

A Phase II Trial Comparing Z-102 With Placebo In Patients With Moderate To Severe Rheumatoid Arthritis (Synergy)

Rheumatoid Arthritis

United States
EMS

Unknown

Comparison of Desloratadine Associated With Prednisolone (Tablet)Versus Dexchlorpheniramine Associated With Betamethasone (Tablet) for Adult Persistent Allergic Rhinitis Treatment

Allergic Rhinitis

Brazil
University of Medicine and Dentistry of New Jersey
National Cancer Institute (NCI)

Terminated

Isotretinoin, Interferon Alfa-2b, Docetaxel, and Estramustine in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy

Prostate Cancer

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Eli Lilly and Company; AstraZeneca; AIDS Clinical Trials... and other collaborators

Completed

ACTIV-2: A Study for Outpatients With COVID-19

Covid19 | Coronavirus

United States, Argentina, Brazil, Guatemala, Mexico, Philippines, Puerto Rico, South Africa, Canada
Kullasate Sakpichaisakul

Recruiting

Vigabatrin With High Dose Prednisolone Combination Therapy vs Vigabatrin Alone for Infantile Spasm

West Syndrome | Infantile Spasm

Thailand
MedSIR
Novartis

Active, not recruiting

Study to Evaluate the Effect of Metformin in the Prevention of HG in HR[+]/HER2[-] PIK3CA-mut Advanced BC Patients (METALLICA)

Breast Cancer

Spain
Khoo Teck Puat Hospital

Completed

Roux-en-Y Gastric Bypass for BMI 27-32 Type 2 Diabetes Versus Best Medical Treatment

Type II Diabetes in Subjects BMI 27 to 32

Singapore
Second Xiangya Hospital of Central South University
The First Affiliated Hospital with Nanjing Medical University; Beijing Hospital and other collaborators

Completed

Protective Effects of Saxagliptin (And Vitamin D3) on β Cell Function in Adult-onset Latent Autoimmune Diabetes

Diabetes Mellitus, Type 1

China
Acacia Pharma Ltd

Completed

Dose-finding Study of APD403 to Prevent Nausea and Vomiting After Chemotherapy

CINV

Denmark
New England Retina Associates
Ocular Therapeutix

Unknown

Evaluation of DEXTENZA in the Management of Pain and Inflammation in Patients With Anterior Uveitis Compared to Standard of Care Topical Corticosteroids (DiverT)

Non-infectious Anterior Uveitis
Replicor Inc.

Completed

REP 2139-Mg and REP 2165-Mg Combination Therapy in Chronic Hepatitis B Infection

Chronic Hepatitis B

Moldova, Republic of
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Safety and Tolerability of Sitagliptin/Simvastatin Fixed-dose Combination (FDC) in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-312)

Type 2 Diabetes Mellitus
Janssen Research & Development, LLC

Completed

Cardiovascular Outcomes in Participants With Type 2 Diabetes Mellitus (T2DM)

Diabetes Mellitus, Type 2

United States
Ewha Womans University Mokdong Hospital

Completed

Analgesic Effects of US Bilateral Rectus Sheath Block for Laparoscopic GY Surgery

Gynecologic Disease

Korea, Republic of
AstraZeneca

Completed

Bioequivalence Study of 2.5-mg Saxagliptin and 500-mg Glucophage in Tablets and a Fixed-dose Combination Tablet in Healthy Participants

Type 2 Diabetes Mellitus

United States
Scotland and Newcastle Lymphoma Group

Unknown

Combination Chemotherapy With or Without Interferon Alfa in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma

Lymphoma

United Kingdom
Samsung Medical Center

Recruiting

Modulating Surgery-Induced Blood-Brain Barrier Disruption in Elderly

Delirium, Postoperative

Korea, Republic of

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