Search clinical trials for: PRO-148 Ophthalmic Solution

Total 2014 results

L.V. Prasad Eye Institute
Allergan

Recruiting

CHED - Congenital Hereditary Endothelial Dystrophy: New Paradigm Shift in Therapy Using Topical Eye Drops

Congenital Hereditary Endothelial Dystrophy of Cornea

India
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical...

Active, not recruiting

A Phase III Clinical Study of the Efficacy and Safety of Two Low-concentration Atropine Sulfate Eye Drops (Mini-CHAMP)

Myopia

China
University of Miami
National Eye Institute (NEI)

Active, not recruiting

Stop Retinal Ganglion Cell Dysfunction Study (STOP-RGCD)

Glaucoma

United States
Hai Yen Eye Care
Brien Holden Vision

Completed

Evaluation of Short Term Use of Experimental Eye Drops BHVI2, 0.02% Atropine and BHVI2 Plus 0.02% Atropine Eye Drops

Myopia

Vietnam
Bausch & Lomb Incorporated

Completed

Assessment of the Concentrations of Besifloxacin, Moxifloxacin, or Gatifloxacin in the Aqueous Humor of Subjects

Cataract Extraction

United States
Campus Bio-Medico University
University of Padova; University of Genova

Completed

Cyclosporin A Eye Drop Treatment in Vernal Keratoconjunctivitis

Vernal Keratoconjunctivitis

Italy
Allergan

Completed

Brimonidine 0.1% Versus Brinzolamide 1% as Adjunctive Therapy to Latanoprost 0.005%

Ocular Hypertension | Glaucoma

United States
Credit Valley EyeCare
Canadian Glaucoma Clinical Research Council

Unknown

Effect of Prophylactic Aqueous Suppression on Hyperencapsulation of Ahmed Glaucoma Valves

Glaucoma

Canada
Zhongshan Ophthalmic Center, Sun Yat-sen University

Unknown

Prospective Study of Deep Anterior Lamellar Keratoplasty Using Acellular Porcine Cornea

Corneal Transplantation

China
Medical University of Vienna

Completed

Local Tolerability of Chitosan-N-acetylcysteine Eye Drops in Healthy Young Volunteers

Dry Eye Syndromes

Austria
Janssen Research & Development, LLC

Terminated

A Study to Investigate Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA Gamma 8) Receptor Occupancy of JNJ-64140284 With Newly Developed Transmembrane AMPA Receptor Regulatory Protein (TARP)-Gamma 8 Positron Emission Tomography (PET) [18F]JNJ-64511070 in Healthy Men

Healthy

Belgium
Merck Sharp & Dohme LLC

Completed

Safety and Pharmacokinetics of Intravenous and Oral Posaconazole in Immunocompromised Children (MK-5592-097)

Neutropenia
Samsung Medical Center
Janssen, LP

Terminated

Evaluation of Antifungal Prophylaxis on Graft-versus-host Disease (GVHD) Patients (ITRAG)

Graft vs Host Disease

Korea, Republic of
University of Maryland, Baltimore

Completed

Itraconazole Oral Absorption

Fungal Infection

United States
Merck KGaA, Darmstadt, Germany

Completed

Supplementation of VigantOL® Oil Versus Placebo as Add-on in Patients With Relapsing Remitting Multiple Sclerosis Receiving Rebif® Treatment (SOLAR)

Relapsing-Remitting Multiple Sclerosis

Germany, Estonia, Latvia, Lithuania, Finland, Austria, Denmark, Netherlands, Portugal, Switzerland, Norway, Italy
Biogen

Withdrawn

Transition to Peginterferon Beta-1a (BIIB017) From Subcutaneous Interferon Therapy (Frequency)

Relapsing Multiple Sclerosis
Ohio State University
University of California, Berkeley; Stanford University; University of Houston; Indiana University and other collaborators

Withdrawn

Delaying the Onset of Nearsightedness Until Treatment Study (DONUT)

Myopia
University of Kansas Medical Center
University of Texas, Southwestern Medical Center at Dallas

Recruiting

Itraconazole to Prevent Recurrent Barrett's Esophagus

Barrett Oesophagitis With Dysplasia

United States
Memorial Sloan Kettering Cancer Center
Comprehensive Cancer Centre The Netherlands

Recruiting

Quality of Life (QoL) Assessment in Cancer Patients and Survivors With Dermatologic Conditions Using Dermatologic QoL Instruments

Cancer | Dermatologic Conditions

United States
Makassed General Hospital

Completed

Nebulized Epinephrine vs. Salbutamol in Bronchiolitis Among Children

Respiratory Distress Score

Lebanon
National Institute of Allergy and Infectious Diseases...

Completed

H5 Vaccine Alone or With Adjuvant in Healthy Adults

Influenza

United States
Tampere University Hospital

Terminated

Intracoronary Administration of Levosimendan in Cardiac Surgery Patients

Myocardial Stunning

Finland
Laboratorios Sophia S.A de C.V.

Completed

Non-inferiority of PRO-122 Ophthalmic Solution vs KRYTANTEK Ofteno® in Glaucoma or Ocular Hypertension (CONFORTK) (CONFORTK)

Primary Open Angle Glaucoma | Ocular Hypertension
Sanofi
Population Health Research Institute

Completed

The ORIGIN Trial (Outcome Reduction With Initial Glargine Intervention) (ORIGIN)

Diabetes Mellitus, Non-Insulin-Dependent

United States, France, Brazil, Poland, Romania, Germany, Italy, Netherlands, Spain, Sweden, Switzerland, Turkey, India, Philippines, Russian Federation, Slovakia, Mexico, Argentina, Croatia, Austria, Denmark, Finland, Hungary, Lithuania, Norw... and more
Novartis Pharmaceuticals

Active, not recruiting

Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy. (V-Mono)

Hypercholesterolemia

United States, Germany, Hungary, Colombia, Mexico
Baylor College of Medicine

Completed

Study of Co-administered Na-APR-1 (M74) and Na-GST-1 in Gabonese Children

Hookworm Infection | Hookworm Disease

Gabon
Forest Laboratories
Ironwood Pharmaceuticals, Inc.

Completed

A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 6-17 Years Who Fulfill Modified Rome III Criteria for Child/Adolescent Functional Constipation (FC)

Functional Constipation in Children Ages 6-17 Years

United States, Canada
National University of Malaysia
Santen Pharmaceutical Co., Ltd.

Unknown

Intracameral Levofloxacin (0.5%) vs Intracameral Cefuroxime

Endophthalmitis Postoperative

Malaysia
Università degli Studi di Brescia

Completed

NSAIDs and PGE2 Levels in Vitrectomy Patients

Vitreous Inflammation
Lin Jiacheng

Unknown

Research of the Application of Triple Antibiotic Paste in Primary Teeth With Pericpical Periodontitis

Periapical Diseases

China
NHS Greater Glasgow and Clyde
Glasgow Caledonian University; Lamellar Biomedical Ltd; Robertson Centre for...

Unknown

LAMELLEYE for the Treatment of Dry Eye Symptoms in pSS Patients

Dry Eye Syndromes | Primary Sjögren Syndrome
Fondation Ophtalmologique Adolphe de Rothschild
Ecouter Voir; Hoya Lens France

Recruiting

Myopia Control in Children: Comparison of Defocus Incorporated Multiple Segments® Lenses Versus Atropine 0.05% Eyedrops (ATROSMART)

Myopia

France
University Hospital of Patras

Completed

Effect of Topical and Oral Diclofenac on Pain Related to Intravitreal Injections

Pain

Greece
Alcon Research

Completed

Study of Efficacy and Safety of Vigadexa in Treating Inflammation and Infection Post-cataract Surgery

Cataract

United States
Eyenovia Inc.

Completed

Study of the Safety, Efficacy and PK of EYN-1601 in Dilation of the Pupil

Mydriasis

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

A Phase 1 Study of Ertugliflozin in Healthy Male Participants (MK-8835-020)

Type 2 Diabetes Mellitus
Universidade Federal Fluminense

Recruiting

Different Endodontic Treatment Techniques in Postoperative Symptoms, Apical Repair, Longevity of Rehabilitations, and Oral Health-related Quality of Life

Edema | Postoperative Pain | Endodontically Treated Teeth | Photochemotherapy

Brazil
Boehringer Ingelheim

Terminated

Study to Assess the Efficacy of Ipratropium Bromide Associated With High Dose Salbutamol by Repeated Nebulisation Versus Repeat Nebulisation of Salbutamol Alone, in Acute Asthmatic Attacks in Young Children

Asthma
Peking University Third Hospital

Completed

Efficacy Comparison of Two Kinds of Treatment in Treating Dry Eye Caused by Meibomian Gland Dysfunction

Dry Eye Syndrome
dingshifang
Shandong Provincial Hospital; Qianfoshan Hospital; Jinan Military General Hospital and other collaborators

Unknown

CYP 2C19 Polymorphism and Voriconazole Trough Concentration in Chinese Adult Patients

Invasive Pulmonary Aspergillosis

China
Fontem Ventures BV

Completed

A Study to Evaluate the Pharmacokinetic Profiles of Cigarettes and E-Cigarettes With Nicotine Salt Formulations

Healthy Volunteers

United States
Otsuka Pharmaceutical, Inc., Philippines

Completed

Comparative Study on the Efficacy and Safety of Procaterol Versus Salbutamol Given Via Metered Dose Inhaler With Spacer in the Management of Acute Asthma Attack in the Emergency Room

Asthma

Philippines
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study to Determine the Impact of Multiple Doses of Rifampin on Single-dose Pharmacokinetics of HCV-796

Healthy
Centro Nacional de Quemados, Uruguay

Unknown

Effect of n-3 PUFA From Fish in Enteral Nutrition of Major Burn Patients (OmegaBurn)

Burn Injury

Uruguay
Boehringer Ingelheim

Completed

A Comparison of Combivent UDV (Ipratropium 500mcg and Salbutamol 2.5mg) and Salbutamol UDV Alone (2.5mg)

Asthma

Philippines
Shanghai Henlius Biotech

Recruiting

Compare the Efficacy and Safety of HLX04-O With Ranibizumab in Subjects With wAMD

Age Related Macular Degeneration

China
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Systemic Pharmacokinetics, Metabolism and Excretion Routes of YM178 in Man, After Administration of Radio-labeled YM178

Metabolic Processes

Netherlands
The Institutes for Pharmaceutical Discovery, LLC
Covance; Mars, Inc.

Completed

Absorption, Metabolism, and Excretion of (-)-[2-14C]Epicatechin in Humans

ADME

United States
ALK-Abelló A/S
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety Study of SCH 900237/MK-8237 in Children and Adults With House Dust Mite-Induced Allergic Rhinitis/Rhinoconjunctivitis (P05607)

Rhinitis, Allergic, Perennial | Rhinitis, Allergic, Nonseasonal
King Faisal University
Mansoura University

Completed

Preoperative Ephedrine Attenuates the Hemodynamic Responses of Propofol During Valve Surgery: A Dose Dependent Study

Valve Surgery | Hypotension

Egypt, Saudi Arabia

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