Search clinical trials for: PT-112

Total 2546 results

Fusion Pharma LLC
Data Matrix Solutions; OCT Rus, LLC; Skolkovo Innovation Center

Unknown

Study to Evaluate Tolerability, Safety, Pharmacokinetics and Preliminary Efficacy of PF-114 for Oral Administration in Adults With Ph+ Chronic Myeloid Leukemia, Which is Resistant to the 2-nd Generation Bcr-Abl Inhibitors or Has T315I Mutation in the BCR-ABL Gene

Leukemia, Myelogenous, Chronic, BCR-ABL Positive | Chronic Myeloid Leukemia

Russian Federation
Jazz Pharmaceuticals

Completed

"Six-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA" (OSA)

Obstructive Sleep Apnea

United States, Finland, Germany, France, Sweden
Raziel Therapeutics Ltd.

Completed

Treatment of Women With Lipedema Involving Substantial Fat Above the Knee or of Women and Men With Nodular Dercum's Disease

Dercum Disease | Lipedema

United States
Johns Hopkins University
National Institute on Aging (NIA)

Completed

PET Imaging Study Using [11C]PIB in Subjects With AD & Healthy Volunteers

Alzheimer's Disease

United States
Synektik S.A.
European Commission

Completed

A Phase I Study of a Novel Tracer for Positron Emission Tomography "PET" Myocardial Perfusion Imaging "MPI"

Coronary Artery Disease
Vanda Pharmaceuticals

Completed

Safety and Efficacy of VEC-162 on Circadian Rhythm in Healthy Adult Volunteers

Circadian Rhythm Sleep Disorders

United States
BioMarin Pharmaceutical

Approved for marketing

BMN 110 US Expanded Access Program

Morquio A Syndrome | MPS IVA | Mucopolysaccharidosis IVA

United States, Puerto Rico
Baylor College of Medicine
Harris County Hospital District; The Methodist Hospital Research Institute

Withdrawn

GOAT; Phase I Open Label Study of CGTG-102, a GM-CSF Encoding Oncolytic Adenovirus, for Advanced Cancers (GOAT)

Solid Tumors | Tumors
Trillium Therapeutics Inc.

Completed

Safety Study of Single Intravesical Doses of TTI-1612 in Women With Interstitial Cystitis/Bladder Pain Syndrome

Interstitial Cystitis

Canada
Xigen SA

Completed

Safety, Tolerability and PK of a Single iv Infusion of 10, 40, and 80 µg/kg XG-102 Administered to Healthy Volunteers

Inflammation

Switzerland
Amgen

Terminated

A Study of AMG 114 Administered by Subcutaneous Injection for the Treatment of Anemia in Subjects With Non-Myeloid Malignancies Receiving Multicycle Chemotherapy

Cancer | Anemia
Supernus Pharmaceuticals, Inc.

Withdrawn

Classroom Study of SPN-812 in Children With ADHD

ADHD
Centre Hospitalier St Anne
Roche Pharma AG

Not yet recruiting

Impact of Microglial Activation on Synaptic Density in Alzheimer's Disease (GliSyn)

Alzheimer Disease

France
Guangzhou University of Traditional Chinese Medicine

Unknown

Study on Vulnerable Plaque of Carotid Artery With Chinese Herbal and Insects Medicine (Spchim)

Carotid Artery Plaque
Guangzhou University of Traditional Chinese Medicine
Liaoning Tumor Hospital & Institute; Zhongshan People's Hospital, Guangdong... and other collaborators

Unknown

Prevention for the Restenosis of Intracranial Artery Stent Implantation Treated With Herbal Medicine C117 (PRISIT)

Occlusion and Stenosis of Unspecified Cerebral Artery
Taysha Gene Therapies, Inc.

Recruiting

Safety and Efficacy of TSHA-102 in Pediatric Females With Rett Syndrome (REVEAL Pediatric Study)

Rett Syndrome

United States, United Kingdom
Multitude Therapeutics Inc.

Recruiting

AMT-116 in Patients With Advanced Solid Tumors

Advanced Solid Tumor

Australia
Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

A Study of ICP-192 in Patients With FGFR2-Rearranged Unresectable or Metastatic Intrahepatic Cholangiocarcinoma

Intrahepatic Cholangiocarcinoma (ICC)

China
Taysha Gene Therapies, Inc.

Recruiting

Safety and Efficacy of TSHA-102 in Adult Females With Rett Syndrome (REVEAL Adult Study)

Rett Syndrome

United States, Canada
Yale University
National Institute on Drug Abuse (NIDA)

Recruiting

SV2A Density Cannabis Use Disorder

Healthy | Cannabis Use Disorder

United States
Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

A Clinical Trial of ICP-192 in Treated Patients With Advanced Solid Tumors With FGF/FGFR Gene Alterations

Advanced Solid Tumor

China
NovalGen Ltd.

Recruiting

First in Human Study of NVG-111 in Relapsed/Refractory ROR1+ Malignancies

Follicular Lymphoma | Mantle Cell Lymphoma | Diffuse Large B Cell Lymphoma | Non-small Cell Lung Cancer (NSCLC) | Small Lymphocytic Lymphoma | Malignant Melanoma | Chronic Lymphocytic Leukaemia

United Kingdom
BrainQ Technologies Ltd.
Sheba Medical Center; The Miami Project to Cure Paralysis; Kessler Institute...

Recruiting

The Use of Electromagnetic Field (EMF) Treatment in Chronic Spinal Cord Injury (SCI) Patients

Incomplete Spinal Cord Injury

Israel, United States
Rahul Parikh
Taiho Oncology, Inc.

Recruiting

A Phase II Study of Lonsurf (TAS-102) in Metastatic Platinum and Checkpoint Inhibitor-resistant Bladder Cancer

Bladder Cancer

United States
Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

Clinical Study of ICP-192 in Solid Tumors Patients

Solid Tumor

China
National Institute of Mental Health (NIMH)

Completed

Evaluation of a Novel PET Radioligand to Image Cyclooxygenase-1 (COX-1)

Normal Physiology

United States
Raziel Therapeutics Ltd.
University of Arizona

Completed

Treatment of Women With Lipedema Involving Substantial Fat Knee of Women and Men With Nodular Dercum's Disease

Dercum Disease | Lipedema

United States
Tammie L. S. Benzinger, MD, PhD

Active, not recruiting

Investigation of Inflammation Using [C-11]-CS1P1 (CS1P1)

Alzheimer Disease

United States
Takeda

Active, not recruiting

A Study of TAK-102 in Adult With Previously-Treated Solid Tumors

Solid Tumors

Japan
REGENXBIO Inc.

Active, not recruiting

RGX-121 Gene Therapy in Children 5 Years of Age and Over With MPS II (Hunter Syndrome)

Mucopolysaccharidosis Type II (MPS II)

United States, Canada
Hope Medicine (Nanjing) Co., Ltd

Completed

To Evaluate the Safety, Tolerability and Efficacy in Male and Female With AGA Treated With HMI-115 Over a 24-week Treatment Period

Androgenetic Alopecia

Australia
Taiho Oncology, Inc.

Terminated

TAS-117 in Patients With Advanced Solid Tumors Harboring Germline PTEN Mutations

Advanced or Metastatic Solid Tumors Irrespective of Gene Alterations | Advanced or Metastatic Solid Tumors With Germline PTEN Inactivating Mutations

United States, United Kingdom, Austria, France
OncoVerity, Inc.
Janssen Research & Development, LLC; argenx

Completed

A Study of ARGX-110 in Participants With Advanced Malignancies

Neoplasms

France, Belgium
Minoryx Therapeutics, S.L.

Active, not recruiting

A Clinical Study in Male Pediatric Patients With Cerebral X-linked Adrenoleukodystrophy (Cald) to Assess the Effects of MIN-102 Treatment on Disease Progression Prior to Human Stem Cell Transplant (HSCT) (NEXUS)

Cerebral Adrenoleukodystrophy

Spain, Germany, France, Argentina
Semnur Pharmaceuticals, Inc.
Worldwide Clinical Trials; Scilex Pharmaceuticals, Inc.

Completed

A Research Study to Characterize the Pharmacodynamics and Safety of Repeat Dose SP-102

Lumbosacral Radicular Pain

United States
Taiho Oncology, Inc.

Completed

A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Renal Impairment

Advanced Solid Tumors

United States, Czechia, Serbia
National Institute of Mental Health (NIMH)

Completed

PET Imaging of Cannabinoid CB1 Receptors Using [11C]MePPEP

Healthy

United States
Taiho Oncology, Inc.

Terminated

An Investigation of TAS-119 Monotherapy

Advanced Solid Tumors

Italy, Spain, United States, Netherlands, United Kingdom
Celgene

Completed

Study to Evaluate Pharmacokinetics of Single Oral Doses of Formulated and Non-Formulated CC-122, and Food Effect Study

Clinical Pharmacology, Healthy Male Volunteer Study

United States
Taiho Oncology, Inc.

Completed

A Study of TAS-116 in Patients With Solid Tumors

Advanced Solid Tumors

United States, United Kingdom, Italy
Placon Therapeutics

Unknown

A Study to Determine the Safety of BTP-114 for Treatment in Patients With Advanced Solid Tumors With BRCA Mutations

Breast Neoplasms | Prostatic Neoplasms | Pancreatic Neoplasms | Ovarian Neoplasms

United States
Oriental Neurosurgery Evidence-Based-Study Team

Unknown

11C-PIB PET/CT in Patients With Parkinson's Disease and Parkinsonian Dementia Syndromes

Parkinson Disease

China
Vidya Raman

Completed

Investigating Reaction Time Among Children Who Snore

Snoring

United States
Taiho Pharmaceutical Co., Ltd.

Completed

A Phase I Study of TAS-102 in Solid Tumors

Advanced or Metastatic Solid Tumors

China
Aerie Pharmaceuticals

Completed

Ocular Hypotensive Efficacy of AR-102

Glaucoma

United States
MetroHealth Medical Center
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Multimodal Treatment for Hemiplegic Shoulder Pain

Stroke | Shoulder Pain

United States
Neogene Therapeutics, Inc.

Recruiting

A Study of NT-112 in HLA-C*08:02-Positive Adult Subjects With Unresectable, Advanced, and/ or Metastatic Solid Tumors Positive for the KRAS G12D Mutation

Endometrial Cancer | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma | Colorectal Carcinoma | Solid Tumor, Adult | KRAS G12D

United States
Combangio, Inc
Kala Pharmaceuticals, Inc.

Recruiting

Trial to Evaluate Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants With PCED (CHASE)

Persistent Corneal Epithelial Defect

United States
Taisho Pharmaceutical Co., Ltd.

Completed

Safety, Pharmacokinetic, and Pharmacodynamic Study of TS-142 in Healthy Subjects

Healthy Volunteer

Japan
Auris Medical AG

Completed

AM-111 in the Treatment of Acute Inner Ear Hearing Loss (HEALOS)

Hearing Loss

Bulgaria

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