Search clinical trials for: PTI-808

Total 3238 results

University of California, Davis

Completed

Mechanisms of Immune Reconstitution & Reduced Immune Activation Following Darunavir-based ART

Human Immunodeficiency Virus Infection

United States
AstraZeneca

Completed

A Multiple Dosing (14 Days) Study to Assess Efficacy and Safety of Three Dose Levels of AZD7594, Given Once Daily by Inhalation, in Patients With Mild to Moderate Asthma

Asthma | Efficacy | Safety

Germany, Bulgaria
Gary Morrow
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

Antibiotic Therapy in Preventing Early Infection in Patients With Multiple Myeloma Who Are Receiving Chemotherapy

Multiple Myeloma | Infection

United States, Peru, South Africa
National Cancer Institute (NCI)

Active, not recruiting

Veliparib, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Non-Hodgkin Lymphoma

Ann Arbor Stage III Non-Hodgkin Lymphoma | Ann Arbor Stage IV Non-Hodgkin Lymphoma | Solid Neoplasm

United States
University of California, San Francisco

Withdrawn

Advance Provision of Medication Abortion

Early Abortion
Gilead Sciences

Completed

Part A: Drug Interaction Study of Sofosbuvir and Antiretroviral Therapy (ART) Combinations in HIV and Hepatitis C Virus (HCV) Co-infected Patients. Part B: Efficacy and Safety of Sofosbuvir for 12 Weeks in HIV/HCV Co-infected Patients.

Hepatitis C | HIV

Puerto Rico
Shaheed Faghihi Hospital
Shiraz University of Medical Sciences

Completed

Effect of Turmeric on Diabetic Nephropathy

Diabetic Nephropathy | Proteinuria

Iran, Islamic Republic of
Dompé Farmaceutici S.p.A
Cross Research S.A.

Completed

Crossover, Single Dose Randomized, Bioequivalence of Ketoprofen Lysine Salt Immediate Release vs Oral Solution

Pain Disorders

Switzerland
Boehringer Ingelheim

Completed

Randomized, Double-Blind, Placebo-Controlled, Forced-Titration, Comparing Telmisartan vs Valsartan. Taken Orally for Eight Weeks in Patients With Stage 1 and Stage 2 Hypertension

Hypertension

United States
Fundacion Oncosur

Completed

Neurotoxicity Characterization Study of Nab-paclitaxel Versus Conventional Paclitaxel in Metastatic Breast Cancer (neurabrax)

Breast Cancer

Spain
Novartis

Completed

To Demonstrate Non-inferiority of Combination of 5 mg Amlodipine/ 80 mg Valsartan to 160 mg Valsartan Alone

Hypertension | High Blood Pressure

Taiwan
Novartis

Completed

Efficacy/Safety of Valsartan Plus Amlodipine and Amlodipine Alone in Patients With Hypertension

Hypertension

China
Montreal Heart Institute
Institut de Recherches Cliniques de Montreal

Recruiting

Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes (APPEASED)

Diabetes Mellitus, Type 2

Canada
University of Virginia
Medical University of South Carolina; National Institute of Neurological Disorders... and other collaborators

Completed

Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial (SHINE)

Hyperglycemia | Diabetes | Acute Ischemic Stroke

United States
GlaxoSmithKline

Completed

Study to Investigate the Stain Control of Two Stannous Fluoride Dentifrices

Oral Hygiene | Extrinsic Dental Stain

Canada
Boehringer Ingelheim

Completed

SMOOTH - Blood Pressure Control in Diabetic/Obese Patients

Hypertension | Diabetes Mellitus, Type 2

Taiwan, Korea, Republic of, United States, New Zealand, Australia, Argentina, Canada, Mexico
Agendia
University of South Florida; University of Miami; University of Oklahoma; Ohio... and other collaborators

Completed

MINT I Multi- Institutional Neo-adjuvant Therapy MammaPrint Project I (MINT)

Breast Cancer

United States
Shanghai University of Traditional Chinese Medicine
Shanghai Chest Hospital; Shanghai Pulmonary Hospital, Shanghai, China

Unknown

Curative Study of Chinese Traditional Medicine to Treat Lung Cancer (TCM)

Cancer
National Cancer Institute (NCI)

Active, not recruiting

Rituximab and Bendamustine Hydrochloride, Rituximab and Ibrutinib, or Ibrutinib Alone in Treating Older Patients With Previously Untreated Chronic Lymphocytic Leukemia

Stage I Chronic Lymphocytic Leukemia | Stage II Chronic Lymphocytic Leukemia | Stage III Chronic Lymphocytic Leukemia | Stage IV Chronic Lymphocytic Leukemia

United States, Canada
Mostafa Bahaa
Sahar El-Haggar, Prof Clinical pharmacy Department- Tanta University; Osama... and other collaborators

Recruiting

Clinical Study to Evaluate the Possible Efficacy and Safety of Levocetirizine in Patients With Diabetic Kidney Disease

Diabetic Nephropathies

Egypt
University of Liverpool
University of Cape Town; Desmond Tutu HIV Foundation; Infectious Diseases Institute... and other collaborators

Completed

Pharmacokinetics of Atazanavir in Special Populations (VirTUAL WP5)

HIV/AIDS | Tuberculosis

Uganda, South Africa
Aziende Chimiche Riunite Angelini Francesco S.p.A
Cross Research S.A.

Completed

Bioequivalence of Ketoprofen Oral Gel vs Ketoprofen Lysine Salt as Granules for Oral Solution

Healthy

Switzerland
Auxilio Mutuo Cancer Center

Unknown

Prophylactic Corticosteroid to Prevent COVID-19 Cytokine Storm

Covid-19

Puerto Rico
Samyang Biopharmaceuticals Corporation

Terminated

Study to Evaluate the Efficacy and Safety Of Intravesical Nanoxel®M In BCG Refractory NMIBC

Non Muscle Invasive Bladder Cancer

Korea, Republic of
Emergo Therapeutics, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Norketotifen in Healthy Subjects

Healthy Subjects

United States
Boehringer Ingelheim

Completed

Trial of Telmisartan 80 mg/HCTZ 12.5 mg and Telmisartan 40 mg/HCTZ 12.5 mg in Patients With Hypertension

Hypertension

Japan
Donald Krogstad
University of the Sciences, Techniques and Technologies of Bamako

Completed

Studies of a Candidate Aminoquinoline Antimalarial (AQ-13)

Malaria

Mali
Boehringer Ingelheim

Completed

Relative Bioavailability of Telmisartan and HCTZ in Two Experimental Formulations Compared to the Standard Formulation Telmisartan and HCTZ in Healthy Female and Male Subjects

Healthy
Boehringer Ingelheim

Completed

A Randomized, Double-blind, Placebo Controlled Comparison of Telmisartan Hydrochlorothiazide (HCT) and Valsartan HCT in Hypertension (HTN) Stage I/II Patients

Hypertension

United States
Memorial Sloan Kettering Cancer Center
University of Texas Southwestern Medical Center; Wake Forest University

Active, not recruiting

Investigating Mechanisms to Explain Age Associated Differences in Quality of Life Among Breast Cancer Patients

Breast Cancer

United States
The First Affiliated Hospital with Nanjing Medical...
Wu Jieping Medical Foundation

Completed

Study on the Level of Neuromuscular Blockade

Neuromuscular Blockade

China
Albert Einstein College of Medicine

Completed

Comparing Five Oral Analgesics for Treatment of Acute Pain in the Emergency Department (ED)

Musculoskeletal Pain

United States
Armando Santoro, MD

Unknown

Study of Combination of PIGEV Before Autologous Stem Cell Transplant in Patients With Hodgkin's Lymphoma

Hodgkin's Lymphoma

Italy
OHSU Knight Cancer Institute
Genentech, Inc.; Oregon Health and Science University

Not yet recruiting

Glofitamab Plus Ibrutinib With Obinutuzumab for the Treatment of Patients With Mantle Cell Lymphoma

Mantle Cell Lymphoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Mantle Cell Lymphoma | Recurrent Follicular Lymphoma | Refractory Follicular Lymphoma | Refractory Marginal Zone Lymphoma | Recurrent Lymphoplasmacytic... and other conditions

United States, Canada
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Ibrutinib, Lenalidomide, and Dexamethasone in Treating Patients With Multiple Myeloma Ineligible for Transplant

Refractory Plasma Cell Myeloma | Recurrent Plasma Cell Myeloma

United States
BioXcel Therapeutics Inc
Cognitive Research Corporation

Recruiting

Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder

Schizophrenia | Bipolar Disorder I | Schizo-Affective Disorder | Schizophreniform; Schizophrenic | Bipolar Disorder II

United States
University of Nebraska
National Institute of Mental Health (NIMH)

Terminated

Dose Response Relationship of Oxytocin on Irritability in Youths

Irritable Mood

United States
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Unknown

Enoxaparin in COVID-19 Moderate to Severe Hospitalized Patients (INHIXACOV19)

COVID-19

Italy
CHU de Quebec-Universite Laval

Completed

Comparison of Doses of Acetylsalicylic Acid in Women With Previous History of Preeclampsia

Premature Birth | Pre-Eclampsia | Fetal Growth Retardation | Placental Insufficiency

Canada
Isarna Therapeutics GmbH

Completed

Phase IIb Clinical Trial With TGF-β2 Antisense Compound AP 12009 for Recurrent or Refractory High-grade Glioma

Glioblastoma | Anaplastic Astrocytoma

Germany, Austria, Georgia, India, Israel, Russian Federation
Patrick Durez

Completed

Study of the Response and Cardiorespiratory Endurance in Early RA Patients Treated With Tocilizumab or Methotrexate (TOMERA)

Rheumatoid Arthritis

Belgium
Ataturk University

Unknown

Ultrasound-Guided Erector Spinae Plan Block in Patients Undergoing ESWL

Pain | Urinary System Stones

Turkey
Sidney Kimmel Cancer Center at Thomas Jefferson...
Susan G. Komen Breast Cancer Foundation

Completed

Carboplatin and Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IIB-IIIC Breast Cancer

Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Triple-negative Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor-negative Breast Cancer | Progesterone Receptor-negative Breast Cancer | HER2-negative Breast Cancer

United States
Merck Sharp & Dohme LLC

Completed

A Study to Compare the Efficacy and Safety of a Combination of Ketoconazole and Clindamycin Compared to Tetracycline/Amphotericin B Combination Cream for the Treatment of Bacterial Vaginosis and Vaginal Candidiasis (P08077)

Vaginosis, Bacterial | Candidiasis, Vulvovaginal
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

ITT4 Intratesticular Hormonal Milieu in Man (ITT4) (ITT4)

Healthy Males

United States
Pfizer

Recruiting

A Study to Learn About the Effectiveness of Cancer Medicines in Patients With Metastatic Non-small Cell Lung Cancer in Norway. (DELINOR)

Non-Small Cell Lung Cancer

Norway
Seoul National University Hospital
Dong-A ST Co., Ltd.

Not yet recruiting

Effect of H2 Receptor Antagonist and Proton Pump Inhibitor on the Positivity Rates and Clinical Outcomes of COVID-19

COVID-19

Korea, Republic of
VA Office of Research and Development

Completed

CSP594 Comparative Effectiveness in Gout: Allopurinol vs. Febuxostat

Chronic Kidney Diseases | Gout

United States
ImmunityBio, Inc.

Active, not recruiting

Combination Immunotherapy Plus Standard-of-Care Chemotherapy Versus Standard-of-Care Chemotherapy for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer

Pancreatic Cancer

United States

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