Search clinical trials for: PYY1-36 sitagliptin

Total 1011 results

GRADE Study Group
Bristol-Myers Squibb; National Institute of Diabetes and Digestive and Kidney... and other collaborators

Completed

A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 Diabetes (GRADE)

Type 2 Diabetes | Comparative Effectiveness of Glycemia-lowering Medications

United States
Novo Nordisk A/S

Completed

Efficacy and Safety of Oral Semaglutide Using a Flexible Dose Adjustment Based on Clinical Evaluation Versus Sitagliptin in Subjects With Type 2 Diabetes Mellitus. (PIONEER 7)

Diabetes Mellitus, Type 2 | Diabetes

United States, Austria, Belgium, Norway, Turkey, Switzerland, Argentina, Korea, Republic of, Brazil, Egypt
Novo Nordisk A/S

Completed

Efficacy and Long-term Safety of Oral Semaglutide Versus Sitagliptin in Subjects With Type 2 Diabetes (PIONEER 3)

Diabetes Mellitus, Type 2 | Diabetes

United States, India, Israel, Japan, Russian Federation, United Kingdom, France, Mexico, South Africa, Turkey, Argentina, Germany, Romania, Brazil, Ukraine
National University of Malaysia

Completed

Glucagon-like Peptide-1 Levels, Insulin Resistance and Insulin Sensitivity Index in Type 2 Diabetes Mellitus (GLP-1)

Type 2 Diabetes Mellitus | PreDiabetes

Malaysia
University of Pennsylvania
Children's Hospital of Philadelphia

Completed

Effect of Chronic Incretin-based Therapy in Cystic Fibrosis

Cystic Fibrosis | Pancreatic Insufficiency

United States
Dong-A ST Co., Ltd.

Completed

A Study to Evaluate the Safety, Tolerability, PK and PD of DA-1241 in Healthy Male Subjects and Subjects With T2DM

Diabetes Mellitus, Type 2

United States
Sherif S. Farag

Completed

Sitagliptin for Prevention of Acute Graft Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation | Graft vs Host Disease

United States
Novartis

Completed

Safety and Tolerability of Vildagliptin Versus Sitagliptin in Patients With Type 2 Diabetes and Severe Renal Insufficiency (28-week Extension Study)

Diabetes Mellitus, Type 2 | Renal Insufficiency

United States
Novartis Pharmaceuticals

Completed

Clinical Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LEZ763

Type II Diabetes

United States
Novartis

Completed

Safety and Tolerability of Vildagliptin Versus Sitagliptin in Patients With Type 2 Diabetes and Severe Renal Insufficiency

Diabetes Mellitus, Type 2

United States
Blandine Laferrere
Merck Sharp & Dohme LLC

Completed

Treatment of Diabetes After Gastric Bypass With Sitagliptin (LAF33)

Type 2 Diabetes Mellitus

United States
Kathleen Dungan

Terminated

Use of Sitagliptin for Stress Hyperglycemia or Mild Diabetes Following Cardiac Surgery

Hyperglycemia | Diabetes Mellitus, Type 2

United States
University of Missouri-Columbia

Terminated

Use of Sitagliptin to Decrease Microalbuminuria

Type 2 Diabetes | Microalbuminuria

United States
Merck Sharp & Dohme LLC

Completed

ALPHA Sitagliptin Add on to Metformin (0431-103)

Diabetes Mellitus
Guangwei Li

Completed

Contribution of Pancreatic αcells Function to Blood Glucose Regulation in Chinese Type 2 Diabetics- the Effect of Sitagliptin on Glucagon Secretion, Insulin Secretion and Insulin Resistance in Chinese Type 2 Diabetics

Insulin Resistance | Insulin Secretion

China
Merck Sharp & Dohme LLC

Completed

Januvia Re-examination Study (MK-0431-181)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

A Study of MK0431 in Patients WIth Hepatic Insufficiency (0431-017)(COMPLETED)

Liver Insufficiency
JW Pharmaceutical

Completed

Efficacy and Safety of CWP-0403 Compared to Sitagliptin in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin Alone (CWP-DIANA-302)

Type 2 Diabetes Mellitus

Korea, Republic of
Lund University

Completed

Effects of Dipeptidyl Peptidase-4 (DPP-4) Inhibition on Hormonal Responses to Macronutrient Ingestion

Healthy | Type 2 Diabetes

Sweden
Institut National de la Santé Et de la Recherche...

Terminated

A Pilot Study Evaluating Safety of Sitagliptin Combined With Peg-IFN Alfa-2a + Ribavirin in Chronic Hepatitis C Patients

Hepatitis C

France
Novartis Pharmaceuticals

Completed

Vildagliptin Versus Sitagliptin - Differences in Fasting Plasma Glucose Lowering Efficacy (FPG-VISIT)

Diabetes Mellitus Type 2

Germany
University of Oslo School of Pharmacy
Oslo University Hospital

Completed

Sitagliptin in Renal Transplant Recipients

Glucose Intolerance

Norway
Kowa Research Institute, Inc.

Completed

A Study Comparing the Safety, Tolerance, and Efficacy of Various Doses of SK-0403 Versus Placebo and Sitagliptin 100 mg in Patients Not Well-Controlled on Metformin Therapy

Type 2 Diabetes

United States
Hannover Medical School

Unknown

Vascular Effects of Sitagliptin in Diabetes Mellitus

Type 2 Diabetes Mellitus

Germany
University of Colorado, Denver

Completed

Assessing Glucose Effects of Sitagliptin (Januvia) in Adult Patients With Type 1 Diabetes

Type 1 Diabetes

United States
Phenomix
Forest Laboratories

Terminated

Study to Evaluate Safety and Efficacy of Dutogliptin in Type 2 Diabetes Mellitus Subjects With Moderate and Severe Renal Impairment

Type 2 Diabetes Mellitus | Renal Impairment

United States, Russian Federation, Ukraine
Merck Sharp & Dohme LLC

Terminated

A Study of the Efficacy and Safety of MK-0431D (a Fixed-dose Combination of Sitagliptin and Simvastatin) for the Treatment of Participants With Type 2 Diabetes Mellitus (T2DM) With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-266)

Type 2 Diabetes Mellitus
AstraZeneca

Completed

Study in Healthy Subjects to Measure Amount of Drug in Blood After Dosing With Different Saxagliptin / Metformin Produc

Bioequivalence, Log-transformed AUCss and Cmax,ss Values for Saxagliptin and Metformin

United States
Merck Sharp & Dohme LLC

Completed

Efficacy and Safety of Sitagliptin/Metformin Fixed-Dose Combination (FDC) Compared to Glimepiride in Participants With Type 2 Diabetes Mellitus (MK-0431A-202)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

Safety and Efficacy of Sitagliptin Compared With Glimepiride in Elderly Participants With Type 2 Diabetes Mellitus (MK-0431-251)

Type 2 Diabetes Mellitus
Novartis Pharmaceuticals

Completed

Effect of Omalizumab on Expression of IgE Receptors in Adults With Severe, Inadequately Controlled Allergic Asthma

Asthma

France
Merck Sharp & Dohme LLC

Completed

Study to Assess Safety & Efficacy of Sitagliptin as Initial Oral Therapy for Treatment of Type 2 Diabetes Mellitus in Pediatric Participants. (MK-0431-083)

Diabetes Mellitus | Type 2 Diabetes
Memorial Sloan Kettering Cancer Center
Evergreen Theragnostics; Recordati Pharmaceutical company

Recruiting

A Study of Pasireotide in People With Prolactinoma

Prolactin-Producing Pituitary Tumor

United States
University of Pittsburgh

Withdrawn

One Week Comparison Study of PTH and PTHrP Infusions

Hyperparathyroidism | Osteoporosis | Bone Diseases, Endocrine | Hypercalcemia of Malignancy

United States
Taipei Veterans General Hospital, Taiwan

Recruiting

To Evaluate the Short-term and Long Term Efficacy of Acupuncture in Ocular and Oral Dryness Symptoms of Dry Eye Syndrome

Dry Eye Syndrome | Xerophthalmia

Taiwan
Ohio State University

Completed

Perioperative Cognitive Protection - Cognitive Exercise and Cognitive Reserve (The Neurobics Trial)

Delirium

United States
AstraZeneca

Completed

Bioequivalence Study of 2.5-mg Saxagliptin and 500-mg Glucophage in Tablets and a Fixed-dose Combination Tablet in Healthy Participants

Type 2 Diabetes Mellitus

United States
Washington University School of Medicine
Merck Sharp & Dohme LLC

Completed

Efficacy Study of Sitagliptin to Prevent New-onset Diabetes After Kidney Transplant

Posttransplant Diabetes Mellitus

United States
University at Buffalo
Merck Sharp & Dohme LLC

Completed

The Effect of Januvia (Sitagliptin) on Oxidative Stress in Obese Type 2 Diabetic Subjects (1928)

Type 2 Diabetes

United States
Merck Sharp & Dohme LLC
Duke Clinical Research Institute, Oxford Diabetes Trials Unit

Completed

Sitagliptin Cardiovascular Outcomes Study (MK-0431-082) (TECOS)

Type 2 Diabetes Mellitus
Eli Lilly and Company

Terminated

A Study of LY2409021 in Participants With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

United States, Puerto Rico, Greece, Taiwan
Lund University
Merck Sharp & Dohme LLC

Completed

Sitagliptin and Glucagon Counterregulation (SITACLAMP)

Type 2 Diabetes

Sweden
Novo Nordisk A/S

Completed

Efficacy and Safety of Switching From Sitagliptin to Liraglutide in Subjects With Type 2 Diabetes Not Achieving Adequate Glycaemic Control on Sitagliptin and Metformin (LIRA-SWITCH™)

Diabetes Mellitus, Type 2 | Diabetes

United States, Israel, Canada, Hungary, India, Spain, Puerto Rico
University Hospital, Gentofte, Copenhagen

Completed

Correlation Between Plasma- and Endothelial DPP-4 Activity

Type 2 Diabetes Mellitus

Denmark
University of Oklahoma

Completed

Sitagliptin Treatment in Patients With Type 2 DM After Kidney Transplant

Type 2 Diabetes | Kidney Transplant

United States
University College Dublin

Completed

Dipeptidyl Peptidase-4 Inhibition and Narrow-band Ultraviolet-B Light in Psoriasis (DINUP) (DINUP)

Psoriasis

Ireland
Ono Pharmaceutical Co. Ltd

Completed

Controlled Study of MK-0431/ONO-5435 in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Japan
Icahn School of Medicine at Mount Sinai
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Withdrawn

Mechanisms Underlying Predictors of Success From Obesity Surgery

Obesity

United States
Cadila Pharnmaceuticals
New Millennium Indian Technology Leadership Initiative (NMITLI) program of...

Completed

Effect of CPL-2009-0031 in the Treatment of Patients With Uncontrolled Type 2 Diabetes Mellitus

Uncontrolled Type 2 Diabetes Mellitus

India
Merck Sharp & Dohme LLC

Completed

Metformin Add-on Regimen Comparison Study in Japanese Participants With Type 2 Diabetes Mellitus (MK-0431A-136)

Type 2 Diabetes Mellitus

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