Search clinical trials for: Paroxetine IR

Total 582 results

Reckitt Benckiser LLC

Completed

Safety and Efficacy of Mucinex and IR Guaifenesin the Treatment of Symptoms of Acute Upper Respiratory Tract Infections

Acute Upper Respiratory Tract Infection

United States
UCB Pharma

Completed

Crossover Study of Neuropsychological Effects of Lacosamide and Carbamazepine Immediate Release in Healthy Subjects

Healthy

United States
GlaxoSmithKline

Terminated

Clinical Evaluation of Ropinirole IR (Immediate Release) Tablets in Patients Who Are Diagnosed With Symptomatic Restless Legs Syndrome (RLS) Associated With Chronic Kidney Disease (CKD) Managed With Haemodialysis (Including Haemofiltration and Haemodiafiltration)

Restless Legs Syndrome

Japan
Prof Dr Jan Tack

Terminated

ANTERO-4: VIPUN Gastric Monitoring System in an Erythromycin Model (ANTERO-4)

Gastric Motility

Belgium
Food and Drug Administration (FDA)
Leiden University; Spaulding Clinical Research LLC

Completed

Effect of Selective Serotonin Reuptake Inhibitors (SSRIs) and an Opioid on Ventilation

Hypercapnia | Ventilatory Depression

United States
Louisiana State University Health Sciences Center...
GlaxoSmithKline

Completed

Lamotrigine Augmentation in Resistant Depression

Unipolar Depression

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

8-Week Study of Tolvaptan Dose Forms in Autosomal Dominant Polycystic Kidney Disease (ADPKD) (NOCTURNE)

Autosomal Dominant Polycystic Kidney Disease

United States
AstraZeneca

Completed

Study Comparing the Tolerability of Seroquel IR With Seroquel XR in Patients With Bipolar Depression

Bipolar Depression
King Abdul Aziz Specialist Hospital

Completed

Entral Feeding in Acute Severe Pancreatitis

Postoperative Nausea

Saudi Arabia
Central Institute of Mental Health, Mannheim

Completed

Amitriptyline and Paroxetine Treatment of Major Depression

Unipolar Depression

Germany
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Group Cognitive Behavioral Therapy Versus Fluoxetine for Obsessive-Compulsive Disorder: a Practical Trial (GCBTVF)

Obsessive Compulsive Disorder

Brazil
Bausch Health Americas, Inc.

Completed

Effects of MNTX on CYP450 2D6 in Metabolizers of Dextromethorphan

Healthy Adults

United States
prof. Peter de Jonge

Unknown

Initial Severity and Antidepressant Efficacy for Anxiety Disorders: an Individual Patient Data Meta-analysis

Anxiety Disorders | Generalized Anxiety Disorder | Social Anxiety Disorder | Panic Disorder | Post-traumatic Stress Disorder | Obsessive-compulsive Disorder
Pfizer

Completed

Clinical Study Assessing a New Scale to Measure Onset of Action in Generalized Anxiety Disorder

Anxiety Disorders

United States
SK Chemicals Co., Ltd.

Completed

Pharmacokinetic Interaction Study of Dapoxetine 30mg and Mirodenafil 50mg

Drug Interaction Potentiation
Mundipharma Research Limited

Terminated

A Study Assessing the Efficacy and Safety of Lodotra® Compared to Prednisone IR in Subjects Suffering From PMR

Polymyalgia Rheumatica

United Kingdom
Dinora, Inc.
PharPoint Research, Inc.; Analgesic Solutions

Terminated

Delayed Release Prednisone in PMR

Polymyalgia Rheumatica

United States
Bristol-Myers Squibb

Completed

Multiple Dose Study In Cancer Patients: Safety and Tolerability of BMS-754807 in Combination With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Solid Tumors

Advanced Solid Tumors | Metastatic Solid Tumors

Korea, Republic of, Canada, Australia
Boehringer Ingelheim

Completed

Bioavailability of Four Oral Prototype Extended Release Formulations With BI 11634 in Healthy Male Volunteers

Healthy
GlaxoSmithKline

Completed

A Study To See If GSK256073A Can Block Niacin-Induced Flushing In Healthy Volunteers

Healthy Subjects | Dyslipidaemias

United States
Yan-Ping Huang

Unknown

Observational Study of Pharmacological Treatment for Premature Ejaculation Concurrent With Erectile Dysfunction

Erectile Dysfunction | Premature Ejaculation
Dong-A ST Co., Ltd.

Completed

Drug Interactions When DA-8010 is Co-administered With Paroxetine or Mirabegron in Healthy Adults

Healthy

Korea, Republic of
H. Lundbeck A/S

Completed

Efficacy of Vortioxetine on Cognitive Dysfunction in Working Patients With Major Depressive Disorder

Major Depressive Disorder

Finland, Germany, Estonia, Lithuania
Forest Laboratories

Completed

Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Adults With Fatigue Associated With Major Depressive Disorder

Major Depressive Disorder

United States
University of Manitoba

Completed

Neuropathic Pain Assessment Comparing Pregabalin and Paroxetine in Management of MS-induced Neuropathic Pain

Multiple Sclerosis | Neuropathic Pain

Canada
Tirat Carmel Mental Health Center
University of Michigan; The Nazareth Hospital, Israel; Ariel University

Completed

Assessment of Pituitary Adenylate Cyclase Activating Polypeptide-Brain Derived Neurotrophic Factor (PACAP-BDNF) Signaling System Involvement in Etiology and Treatment of Major Depression

Major Depression

Israel
Ensysce Biosciences

Completed

A Study to Evaluate the Intranasal Abuse Potential of PF614 in Non-Dependent Recreational Opioid Users

Recreational Drug Use

United States
Grünenthal GmbH

Completed

A Clinical Study in Healthy Adults Who Sometimes Take Drugs for Pleasure Which Aims to Evaluate Whether GRT0151Y is Likely to be Abused

Pain | Acute Pain

Canada
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Concomitant Use of PriLigy in Men Treated for Erectile Dysfunction (COUPLE)

Sexual Dysfunction | Erectile Dysfunction

France, Poland, United States, Belgium, Mexico, Malaysia, Canada, Taiwan, Korea, Republic of, Russian Federation, Argentina, Australia, United Kingdom
Pfizer

Completed

Relative Bioavailability Study of a Modified-Release Formulation of PF-06865571 in Healthy Adult Participants

Healthy Participants

Belgium
Boehringer Ingelheim

Completed

Pramipexole Pilot Phase II Study in Children and Adolescents With Tourette Disorder According to DSM-IV Criteria

Tourette Syndrome

United States, Germany
Astellas Pharma Global Development, Inc.

Completed

A Phase I Study to Compare 3 Different Strengths of an Extended Release Formulation of ASP015K to an Immediate Release Formulation of ASP015K

Healthy Volunteers | Pharmacokinetics of ASP015K | Food Effect

United States
Boehringer Ingelheim

Completed

Increasing Dose Study of Pramipexole in Two-way Cross-over Comparison of ER Tablet Versus IR Tablet in Japanese Healthy Male Volunteers

Healthy
Eisai Inc.
Eisai Limited

Completed

Comparison of 23 mg Donepezil Sustained Release (SR) to 10 mg Donepezil Immediate Release (IR) in Patients With Moderate to Severe Alzheimer's Disease

Alzheimer's Disease

United States
University of California, Irvine

Recruiting

Treatment of Tinnitus With Migraine Medications

Tinnitus, Subjective | Tinnitus

United States
Eli Lilly and Company
Boehringer Ingelheim

Completed

A Study Comparing Duloxetine to Other Antidepressants in the Treatment of Severe Depression (TRY FIRST)

Depression

United States
AstraZeneca

Completed

A Study to Estimate the Effect of AZD5718 on the Pharmacokinetics (What Does the Body Does to the Drug) of Rosuvastatin to Measure the Relative Bioavailability (the Extent to Which a Drug or Other Substance Becomes Available to the Body) of AZD5718 Oral Suspension vs AZD5718 Immediate Release Tablet

High Risk Coronary Artery Disease

United Kingdom
Johns Hopkins University
National Institute of Mental Health (NIMH)

Completed

Study of Paroxetine and Fluconazole for the Treatment of HIV Associated Neurocognitive Disorder (ParaFlu)

HIV Associated Neurocognitive Disorder

United States
Yale University

Completed

Naltrexone & SSRI in Alcoholics With Depression/PTSD

Depression | PTSD | Alcoholism

United States
University Medicine Greifswald

Completed

Effects of 500 mg Immediate Release and Extended Release Methylnaltrexone on Loperamide-induced Delay of the Oro-cecal and Whole-gut Transit Time in Healthy Subjects (LOP-MNTX-2009)

Intestinal Obstruction

Germany
Depomed

Completed

Study in Advanced Parkinson's Disease Patients With Predictable Motor Fluctuations

Parkinson's Disease | Motor Fluctuations

United States
Beijing Children's Hospital

Unknown

Population Pharmacokinetics of Cephalosporins and Macrolides in Chinese Children With Community Acquired Pneumonia

Community Acquired Pneumonia

China
Trevena Inc.

Completed

A Safety, Tolerability, PD and PK Study in Healthy Adults

Healthy

United States
Sheba Medical Center

Completed

The Effect of Methylphenidate Treatment in Familial Attention Deficit/Hyperactivity Disorder (ADHD)

ADHD Predominantly Inattentive Type | Attention Deficit/Hyperactivity Disorder Combined Type | ADHD Predominantly Hyperactivity Type | ADHD-not Other Specified

Israel
Tong Lee

Completed

Open-label, Normal Healthy Volunteer Clinical Trial of a Novel Ondansetron Formulation

Healthy

United States
Astellas Pharma Europe B.V.

Completed

A Study to Compare the Actions in the Body of Healthy Subjects of Three Modified Release Formulations of YM178 Under Fasted and Fed Conditions With One Immediate Release Formulation of YM178 Under Fasted Conditions

Healthy Subjects | Pharmacokinetics of YM178

Netherlands
Otsuka Pharmaceutical Development & Commercialization...

Completed

Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial) (Orion)

Mental Disorders | Depressive Disorder | Depression | Mood Disorders | Depressive Disorder, Major

United States, France, Poland, Russian Federation, Romania, Ukraine, Germany, Hungary, Slovakia, Serbia, Canada
Robert Bosch Gesellschaft für Medizinische Forschung...

Completed

Influence of Pharmacogenetic Factors, Paroxetine and Clarithromycin on Pharmacokinetics of Clomiphene

Anovulation | Cytochrome P450 CYP3A Enzyme Deficiency | Disorder Due Cytochrome P450 CYP2D6 Variant

Germany
GlaxoSmithKline

Completed

A Phase I/II Clinical Study of SK&F-105517-D in Japanese Patients With Chronic Heart Failure

Heart Failure, Congestive

Japan
Boehringer Ingelheim

Completed

The SUSTAIN Study Compares the Effects of Sustained and Immediate-release Pramipexole on the noctUrnal Symptoms of paTients With Advanced ParkInsoN's Disease Who Also Take L-Dopa

Parkinson Disease

China

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