Search clinical trials for: Part 1: DCM Cohort

Total 627 results

Pfizer
Halozyme Therapeutics

Terminated

Pharmacokinetic and Pharmacodynamic Study of Bococizumab Alone and When Combined With Recombinant Human Hyaluronidase

Healthy | Hypercholesterolemia

Belgium
Hutchmed
BeiGene

Active, not recruiting

Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid Tumors

Soft Tissue Sarcoma | Small Cell Lung Cancer | Gastric Cancer | Colorectal Cancer | Neuroendocrine Tumors | Metastatic Solid Tumor | Anaplastic Thyroid Cancer

United States
MassBiologics

Terminated

Open Label Study of the Efficacy and Safety of MBL-HCV1 in Combination With Oral Direct-Acting Antivirals in Patients Undergoing Liver Transplantation for Hepatitis C (MBL-HCV1)

Hepatitis C Infection

United States
Bexion Pharmaceuticals, Inc.
CTI Clinical Trial and Consulting Services

Recruiting

A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG) (KONQUER)

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant

United States
Novartis Pharmaceuticals

Completed

A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Hepatic Impairment Compared With Matched Healthy Participants

Hepatic Impairment

Hungary
Acceleron Pharma Inc. (a wholly owned subsidiary...

Terminated

Extension Study of ACE-031 in Subjects With Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

Canada
New Mexico Cancer Care Alliance

Completed

Use of Hydralazine and Valproic Acid in Advanced Solid Tumor Malignancies

Lung Cancer

United States
Asahi Kasei Pharma Corporation

Completed

Exploratory Study of ART-123 for the Prevention of Cancer Treatment Related Symptoms in Patients With Postoperative Stage II / III Colon Cancer

Postoperative Stage II/III Colon Cancer

Japan
Weill Medical College of Cornell University

Recruiting

A Pilot Study to Determine Fructose Uptake by Primary Human Colorectal Tumors

Colorectal Tumors

United States
Ardea Biosciences, Inc.

Completed

RDEA3170 Tablet and Capsule Bioavailability Study

Healthy

United States
MedImmune LLC
Thrombolysis in Myocardial Infarction (TIMI) Study Group

Completed

A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction (REAL-TIMI 63B)

ST Elevation Myocardial Infarction

Netherlands, United Kingdom, Brazil, Spain, Slovakia, Israel, Czechia, Hungary, Poland, Russian Federation
Hanlim Pharm. Co., Ltd.

Completed

A Clinical Trial to Evaluate Tolerability and Pharmacokinetics of HL217 Eye Drop in Healthy Male Subjects

Healthy Subject
Yonsei University

Completed

Neoadjuvant Combination Chemotherapy of DCS (Cisplatin + Docetaxel + S-1) and DCF (Docetaxel + Cisplatin + 5-FU) in Patients With Locally Advanced Gastric Adenocarcinoma

Gastric Cancer

Korea, Republic of
Hoffmann-La Roche

Completed

A Two-part, Single-dose, Randomized Study to Evaluate the Safety of Supra-therapeutic Doses of RO7033877 and to Investigate the Effect of RO7033877 on the QTc Interval

Healthy Volunteer

United States
AstraZeneca

Completed

AZD8186 First Time In Patient Ascending Dose Study

Advanced Castrate-resistant Prostate Cancer CRPC | Squamous Non-Small Cell Lung Cancer sqNSCLC | Triple Negative Breast Cancer TNBC

Spain, Canada, United States, United Kingdom
St George's, University of London

Unknown

Study of Single IV Administration of P2G12 (FuturePharma)

HIV Infection

United Kingdom
Laboratorios Hipra, S.A.

Completed

Safety and Immunogenicity Study of Recombinant Protein RBD Candidate Vaccine Against SARS-CoV-2 in Adult Healthy Volunteers (COVID-19)

Covid19 | SARS CoV 2 Infection

Spain
Tyra Biosciences, Inc

Recruiting

Safety and Anti-Tumor Activity of TYRA-200 in Advanced Cholangiocarcinoma With Activating FGFR2 Gene Alterations (SURF201)

Solid Tumor | Intrahepatic Cholangiocarcinoma | Metastatic Cholangiocarcinoma | Locally Advanced Cholangiocarcinoma

United States
Sciwind Biosciences APAC CO Pty. Ltd.
Hangzhou Sciwind Biosciences Co., Ltd.

Completed

To Evaluate the Safety, Tolerability, PK, and PD of XW003 Injection in Healthy Adult Participants (XW003)

Obesity | Type 2 Diabetes Mellitus | Nonalcoholic Steatohepatitis

Australia
New York Medical College

Recruiting

Chemoradiotherapy With Targeted Immunotherapy in Pediatric Lymphoma (RADICAL)

Hodgkin Lymphoma | Non-hodgkin Lymphoma

United States
Hamilton Health Sciences Corporation

Completed

The Effects Of Methacholine Challenge Administered Using Three Different Nebulizers On Small Airways Function

Asthma

Canada
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Nivolumab for Pediatric and Adult Relapsing/Refractory ALK+, for Evaluation of Response in Patients With Progressive Disease (Cohort 1) or as Consolidative Immunotherapy in Patients in Complete Remission After Relapse (Cohort 2) (NIVO-ALCL)

Relapsing/Refractory ALK+ Anaplastic Large Cell Lymphoma

France, Denmark, Netherlands
Gilead Sciences

Completed

Safety, Tolerability, Pharmacokinetics and Antiviral Activity of GS-9669 in Subjects With Chronic Hepatitis C Virus Infection

Hepatitis C

United States, Puerto Rico
University of Aarhus
The Danish Rheumatism Association

Active, not recruiting

Functional Exercise Tests in Patients With Systemic Sclerosis

Scleroderma, Systemic | Pulmonary Arterial Hypertension | Lung Diseases, Interstitial | Acroosteolysis

Denmark
University of Pittsburgh
Dalhousie University; National Institute on Disability, Independent Living,...

Recruiting

Improving Clinician Capacity to Provide Interventions for Manual Wheelchair Users (SKILL)

Wheelchair Skills

United States
Genzyme, a Sanofi Company

Unknown

Vaccine Therapy in Treating Patients Who Have Stage II, Stage III, or Stage IV Melanoma

Melanoma (Skin)

United States
The Lymphoma Academic Research Organisation
French Innovative Leukemia Organisation

Completed

Escalating Doses of Torisel in Combination With Three Chemotherapies Regimens: R-CHOP, R-FC or R-DHA for Patients With Relapsed/Refractory Mantle Cell Lymphoma (MCL). (T³)

Mantle Cell Lymphoma Refractory

France
Zonguldak Bulent Ecevit University

Unknown

Hypervolemia in ESRD Patients in Zonguldak (Prospective Study)

Hemodialysis Fluid Allergy

Turkey
Regeneron Pharmaceuticals

Active, not recruiting

A Study to Test if Trevogrumab or Trevogrumab With Garetosmab When Taken With Semaglutide is Safe and How Well They Work in Adult Patients With Obesity for Weight Loss and Fat Loss (COURAGE)

Obesity

United States
Celldex Therapeutics

Terminated

A Study of Glembatumumab Vedotin as Monotherapy or in Combination With Immunotherapies in Patients With Advanced Melanoma

Melanoma

United States
Abramson Cancer Center at Penn Medicine

Active, not recruiting

Evaluating in Vivo PARP-1 Expression With 18F-FluorThanatrace Positron Emission Tomography (PET/CT) in Prostate Cancer

Prostate Cancer

United States
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Safety of Furosemide in Premature Infants at Risk of Bronchopulmonary Dysplasia (BPD)

Bronchopulmonary Dysplasia

United States
Jonsson Comprehensive Cancer Center
National Institutes of Health (NIH)

Completed

Vaccine Therapy in Treating Patients With Stage IV or Recurrent Malignant Melanoma

Melanoma (Skin)

United States
Hoth Therapeutics, Inc.
Novotech (Australia) Pty Limited

Completed

Safety, Tolerability, Pharmacokinetics and Efficacy of Twice Daily Application of Topical BioLexa in Adult Healthy Subjects and Patients With Mild to Moderate Atopic Dermatitis

Atopic Dermatitis

Australia
Ataturk University

Completed

The Effect of Laughter Yoga on the Anxiety and Stress Levels of Women in the Postpartum Period

Laughter Yoga

Turkey
Centocor, Inc.

Completed

A Long-term Safety Study of Infliximab in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD).

Pulmonary Disease, Chronic Obstructive | COPD

United States
SENAI CIMATEC

Recruiting

Study to Assess Safety, Reactogenicity and Immunogenicity of the VACCINE RNA MCTI CIMATEC HDT (HDT-301) Vaccine Against COVID-19

SARS-CoV-2

Brazil
EMD Serono

Terminated

Sym004 in Subjects With Stage IV Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States, Germany
Centre hospitalier de l'Université de Montréal...
Université de Montréal

Completed

Online Perceptual Modules and Spaced Learning, a Modern Approach to Teaching LVEF Assessment to Medical Students. (MAP-ETT)

Medical Education

Canada
Mayo Clinic

Recruiting

Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia

Recurrent Chronic Myelomonocytic Leukemia | Refractory Chronic Myelomonocytic Leukemia

United States
Jemincare

Recruiting

Safety, Tolerability of JMKX003002 in Phase 1 Study in Healthy Subjects

Safety and Tolerability

China
Jemincare
Zhejiang Hangyu Pharmaceutical Co., Ltd

Recruiting

Phase 1 Clinical Study of JMKX003142 Tablets

Safety and Tolerability

China
Phost'In Therapeutics

Recruiting

First-in-human Trial of PhOx430, a First-in-class Acetylglucosaminyltransferase V Inhibitor, in Advanced Solid Tumours (PhAST)

Glioblastoma Multiforme | Metastatic Cancer | Advanced Solid Tumor | Malignant Tumor

Italy, France
ProQR Therapeutics

Completed

Study to Evaluate Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene (Stellar)

Eye Diseases | Retinitis Pigmentosa | Eye Diseases, Hereditary | Vision Disorders | Retinal Disease | Eye Disorders Congenital | Usher Syndrome Type 2 | Deaf Blind

United States, Canada, France
Pfizer

Completed

Investigational Agent AG-013736 In Combinations With Standard Of Care Treatments For Patient's With Advanced Solid Tumor

Neoplasms

Poland, United States, Spain
Cyclacel Pharmaceuticals, Inc.
M.D. Anderson Cancer Center

Unknown

Study of Sapacitabine in Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS)

Acute Myeloid Leukemia | Myelodysplastic Syndromes

United States
Jonsson Comprehensive Cancer Center

Completed

Vaccine Therapy in Treating Patients With Stage IV or Relapsed Malignant Melanoma

Melanoma

United States
Uppsala University

Completed

Neo-adjuvant Chemo + Peritonectomy + Hyperthermic Intraperitoneal Chemo in Peritoneal Carcinomatosis From Gastric Cancer

Gastric Cancer | Peritoneal Carcinomatosis

Sweden
Seoul National University Hospital

Completed

A Clinical Trial for Analysis of Intestinal Microbiome Affecting PK, PD, and Safety of Metformin

Human Microbiome

Korea, Republic of
University of the Incarnate Word
National Eye Institute (NEI)

Completed

Impact of Color Correcting Lenses on Color Vision Deficiency

Color Vision Defects | Color Blindness | Color Blindness, Red | Color Blindness, Green

United States

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