Search clinical trials for: Pegylated Irinotecan

Total 2126 results

Joel Neal
Nektar Therapeutics

Completed

Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer

Tumors Metastatic to Brain | Stage IV Non-small Cell Lung Cancer (NSCLC) | Recurrent Non-small Cell Lung Cancer (NSCLC) | Extensive-stage Small Cell Lung Cancer (SCLC) | Recurrent Small Cell Lung Cancer (SCLC) | Metastatic Breast Cancer (mBC)

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI); Nektar Therapeutics

Completed

Pegylated Irinotecan NKTR 102 in Treating Patients With Relapsed Small Cell Lung Cancer

Recurrent Small Cell Lung Carcinoma

United States
Nektar Therapeutics

Completed

NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer

Colorectal Cancer

United States, Belgium, Germany, India, Spain, United Kingdom
Alchemia Oncology

Unknown

Trial of FOLF(HA)Iri Versus FOLFIRI in mCRC (FOLF(HA)iri)

Metastatic Colorectal Cancer

Australia
Abramson Cancer Center of the University of Pennsylvania

Completed

Etirinotecan Pegol (NKTR-102) in NSCLC

Metastatic Non Small Cell Lung Cancer | Recurrent Non Small Cell Lung Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Liposomal Irinotecan and Veliparib in Treating Patients With Solid Tumors

Malignant Solid Neoplasm

United States
Xiamen Amoytop Biotech Co., Ltd.
Peking Union Medical College Hospital

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Pegylated-Somatropin in Healthy Volunteers (Somatropin)

Healthy

China
Prolong Pharmaceuticals

Completed

Study to Assess the Safety and Impact on Humoral Sensitization of SANGUINATE in Patients With End Stage Renal Disease

Renal Insufficiency, Chronic

United States
Xiamen Amoytop Biotech Co., Ltd.

Completed

PK & PD Study of Pegylated rhEPO, and Evaluated Its Safety and Tolerability in Male Healthy Individual

Healthy

China
Hallym University Medical Center
Jeil Pharmaceutical Co., Ltd.

Unknown

Study of Oxaliplatin, Irinotecan, and S-1 in Biliary Tract Cancer

Biliary Tract Neoplasm

Korea, Republic of
The First Hospital of Jilin University

Recruiting

Mecapegfilgrastim(PEG-G-CSF) for Prophylaxis of Chemotherapy-induced Neutropenia in Patients With Lymphoma

Lymphoma | Chemotherapy-induced Neutropenia

China
Prolong Pharmaceuticals

Completed

A Phase 1 Safety Study of SANGUINATE™ In Patients With Acute Severe Anemia.

Acute Anemia

United States
Ludwig Institute for Cancer Research
Memorial Sloan Kettering Cancer Center; National Taiwan University Hospital; Duke... and other collaborators

Terminated

Study of ADI-PEG 20 in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer

Small Cell Lung Cancer

United States, Taiwan, Germany, Belgium, United Kingdom
Hallym University Medical Center
Jeil Pharmaceutical Co., Ltd.

Completed

Study of Oxaliplatin, Irinotecan, and S-1 in Gastric Cancer

Stomach Neoplasm

Korea, Republic of
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Pembrolizumab and PEGPH20 in Treating Patients With Metastatic Pancreatic Cancer

Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma

United States
Eisai Inc.
Halozyme Therapeutics

Terminated

Study of Eribulin Mesylate in Combination With PEGylated Recombinant Human Hyaluronidase (PEGPH20) Versus Eribulin Mesylate Alone in Subjects With Human Epidermal Growth Factor Receptor 2 (HER2)-Negative, High-Hyaluronan (HA) Metastatic Breast Cancer (MBC)

Metastatic Breast Cancer

United States
Prolong Pharmaceuticals

Withdrawn

A Study on SANGUINATE™ for the Reduction of Delayed Graft Function in Kidney Transplant Patients

Delayed Function of Renal Transplant
Prolong Pharmaceuticals

Completed

Efficacy and Safety of SANGUINATE™ for Reduction of Delayed Graft Function in Patients Receiving a Kidney Transplant

Delayed Function of Renal Transplant

United States
Nektar Therapeutics

Completed

NKTR-102 in Combination With Cetuximab in Patients With Refractory Solid Tumors (Phase 2a) and Metastatic or Locally Advanced Colorectal Cancer (Phase 2b)

Colorectal Cancer | Tumor

United States
Shanghai Zhangjiang Biotechnology Limited Company
Shanghai Biomabs Pharmaceutical Co., Ltd.

Completed

Study of CMAB009 to Treat KRAS Wild Type Metastatic Colorectal Cancer (CRC009)

Metastatic Colorectal Cancer
Prolong Pharmaceuticals

Completed

Study of SANGUINATE™ In the Treatment of Sickle Cell Disease Patients With Vaso-Occlusive Crisis

Anemia, Sickle Cell

United States
ShengFa Su

Unknown

Irinotecan Plus Lobaplatin Versus Irinotecan in the Second-line Treatment of Small Cell Lung Cancer

Small-cell Lung Cancer

China
Cancer Institute and Hospital, Chinese Academy...
Zhejiang Cancer Hospital; Changhai Hospital; Fudan University; Fujian Cancer Hospital and other collaborators

Completed

A Study Comparing Pegylated Filgrastim and Filgrastim in Support for Chemotherapy

Cancer
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Study of Pegylated rhG-CSF as Support to Advanced Non-Small-Cell Lung Cancer (NSCLC) Patients Receiving Chemotherapy Receiving Chemotherapy

NSCLC | Neutropenia | Febrile Neutropenia

China
Pfizer
Hospira, now a wholly owned subsidiary of Pfizer

Completed

A Study Of The Safety And Effects Of One Or More Doses Of HSP-130 Injected Under The Skin In Women With Breast Cancer That Has Not Spread To Distant Sites In The Body.

Non-metastatic Breast Cancer

Hungary, Spain
Marval Pharma Ltd.

Terminated

Single Dose Safety, Tolerability and Pharmacokinetic Study of NCTX in Healthy Volunteers

Healthy Volunteers

United States
H. Lee Moffitt Cancer Center and Research Institute

Terminated

Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and Oligodendrogliomas

Glioma | Astrocytoma | Oligodendroglioma

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Study Comparing Pegylated rhG-CSF and rhG-CSF as Support to Breast Cancer Patients Receiving Chemotherapy

Breast Cancer | Neutropenia | Febrile Neutropenia

China
Nelson Yee
Ipsen

Active, not recruiting

Liposomal Irinotecan in Combination With Oxaliplatin, Leucovorin, and 5-fluorouracil for Patients With Locally Advanced Pancreatic Carcinoma:

Locally Advanced Pancreatic Carcinoma(LAPC)

United States
Centre Oscar Lambret
SFCE

Completed

Vincristine and Irinotecan With or Without Temozolomide in Children and Adults With Refractory/Relapsed Rhabdomyosarcoma (VIT-0910)

RHABDOMYOSARCOMA

France
Boston Scientific Corporation
Biocompatibles UK Ltd

Completed

Study of Chemoembolisation Using Irinotecan Bead Prior to Surgery in Metastatic Colorectal Cancer (PARAGON-II)

Metastatic Colorectal Cancer

United Kingdom, Austria, France
Baohui Han

Not yet recruiting

Safety and Efficacy of Adebrelimab Plus Irinotecan Liposome (II) With or Without Famitinib in ES-SCLC Pre-treated With Immunotherapy

Extensive-stage Small-cell Lung Cancer

China
National Cancer Institute (NCI)

Completed

Genetic Testing Plus Irinotecan in Treating Patients With Solid Tumors or Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Japan Clinical Cancer Research Organization
Taiho Pharmaceutical Co., Ltd.

Completed

Second Line Chemotherapy for S-1 Refractory Advanced Gastric Cancer

Gastric Cancer

Japan
Prolong Pharmaceuticals

Completed

A Study of SANGUINATE for the Treatment of Vaso-occlusive Crisis (VOC) in Adult Sickle Cell Disease Patients

Anemia, Sickle Cell

Colombia, Panama, Dominican Republic, Honduras
Fudan University

Not yet recruiting

Irinotecan Liposome Combined With Anlotinib as Second-line Regimen for SCLC

Small Cell Lung Cancer Recurrent

China
Dong-A University Hospital
Pusan National University Yangsan Hospital

Completed

FOLFOX Followed by FOLFIRI or Reverse Sequence Treatment in Advanced Gastric Cancer (AGC)

Gastric Cancer

Korea, Republic of
Bristol-Myers Squibb

Completed

A Phase II Study of Carboplatin Plus Irinotecan Versus Irinotecan in Children With Refractory Solid Tumors

Neoplasms

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

PLX038 for Treatment of Metastatic Platinum-resistant Ovarian, Primary Peritoneal, and Fallopian Tube Cancer

Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Platinum-Resistant Ovarian Carcinoma | Stage IV Fallopian Tube Cancer AJCC v8 | Stage IV Ovarian Cancer AJCC v8 | Stage IV Primary Peritoneal Cancer AJCC v8

United States
University of California, Irvine

Withdrawn

A Pilot Study of Irinotecan in Patients With Breast Cancer and CNS Metastases

Male Breast Cancer | Stage IV Breast Cancer | Recurrent Breast Cancer | Central Nervous System Metastases
Fundació Institut de Recerca de l'Hospital de la...

Unknown

Study to Evaluate the Efficacy and Safety of FOLFIRI-AD in Patients With Metastatic Colorectal Cancer UGT1A Genotype 1 (FOLFIRI-AD)

Metastatic Colorectal Cancer

Spain
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Irinotecan in Treating Children With Refractory Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Ewing Sarcoma/Peripheral... and other conditions

United States
Jiangsu T-Mab Biopharma Co.,Ltd

Unknown

Study to Assess the Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of GW003 in Patients With Breast Cancer

Chemotherapy-induced Neutropenia

China
Ascension Healthcare Development Limited

Recruiting

A Pharmacokinetic and Clotting Activity Study of FVIII-PEGLip

Hemophilia A With Inhibitor

Russian Federation
ZymoGenetics

Completed

Study of PEG-rIL-29 (or PEG-IFN Lambda) in Subjects With Chronic Hepatitis C Virus Infection

Hepatitis C, Chronic

United States, Canada
Swiss Group for Clinical Cancer Research

Completed

Combination Chemotherapy in Treating Patients With Advanced or Metastatic Colorectal Cancer

Colorectal Cancer

Switzerland
Institut du Cancer de Montpellier - Val d'Aurelle

Completed

Sorafenib in Combination With Irinotecan in Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors (NEXIRI2)

Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors

France
Dutch Colorectal Cancer Group
Sanofi; Hoffmann-La Roche; Koningin Wilhelmina Fonds

Completed

Sequential Versus Combination Chemotherapy in Advanced Colorectal Carcinoma

Advanced Colorectal Cancer
Sabine Mueller, MD, PhD
Pacific Pediatric Neuro-Oncology Consortium; The V Foundation for Cancer Research

Completed

CED With Irinotecan Liposome Injection Using Real Time Imaging in Children With Diffuse Intrinsic Pontine Glioma (DIPG) (PNOC 009)

Diffuse Intrinsic Pontine Glioma

United States
Advocate Health Care

Withdrawn

Evaluation of Low-dose Irinotecan and Cyberknife® SBRT to Treat Colorectal Cancer With Limited Liver Metastasis

Colorectal Cancer

United States

Search clinical trials for: Pegylated Irinotecan

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bosnia & Herzegovina

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations