Search clinical trials for: pemetrexed and cisplatin

Total 273497 results

GlaxoSmithKline

Terminated

A Study to Evaluate Pazopanib in Comparison to Pemetrexed in Maintenance Setting in Non-progressing Subjects With Metastatic Stage IVA and IVB Non-squamous Non-small Cell Lung Cancer (NSCLC) Population

Lung Cancer, Small Cell

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Pemetrexed Disodium in Treating Patients With Recurrent Cancer of the Cervix

Cervical Cancer

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Terminated

S0526: Pemetrexed Disodium in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer

Lung Cancer

United States
Taiho Pharmaceutical Co., Ltd.

Completed

Randomized Phase III Study of TS-1 Alone Versus TS-1 Plus CDDP in Advanced Gastric Cancer

Gastric Cancer

Japan
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

A Prospective, Single-arm Clinical Study of Pabrolizumab in Combination With Cisplatin + 5-FU for the Neoadjuvant Treatment of Unresectable, Advanced Squamous Carcinoma of the Temporal Bone Single-arm Clinical Study

Temporal Bone Squamous Cell Carcinoma

China
University Hospital Tuebingen

Terminated

Randomized Controlled Trial to Prevent Peritoneal Seeding in Gastric Cancer (HIPECStomach)

Gastric Cancer | Peritoneal Carcinomatosis

Germany
Fudan University

Completed

Clinical Value of Sequential Gefitinib With Pemetrexed/Platinum for Advanced NSCLC

NSCLC

China
Merck Sharp & Dohme LLC

Completed

A Study of Pembrolizumab in Combination With Cisplatin and Pemetrexed in Advanced Malignant Pleural Mesothelioma (MPM) (MK-3475-A17)

Mesothelioma

Japan
Eli Lilly and Company

Completed

A Study of Induction and Maintenance Treatment of Advanced Non-squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

United Kingdom, Germany, Poland, Belgium, Spain, Italy, Greece, Australia, Netherlands, Romania, France, India, Finland, Turkey, Portugal
NovoCure Ltd.

Completed

Safety and Efficacy of TTFields (150 kHz) Concomitant With Pemetrexed and Cisplatin or Carboplatin in Malignant Pleural Mesothelioma (STELLAR)

Malignant Pleural Mesothelioma

Netherlands, Italy, Germany, Belgium, France, Poland, Spain
National Cancer Institute (NCI)

Terminated

SS1(dsFV)PE38 Plus Pemetrexed and Cisplatin to Treat Malignant Pleural Mesothelioma

Mesothelioma

United States
Chonnam National University Hospital
Sanofi

Terminated

TaxoteRe Plus Cisplatin Versus AlImta Plus Cisplatin in 1st Line Non-squamous Cell Type Lung Cancer (TRAIL)

Carcinoma, Non Small Cell Lung

Korea, Republic of
University of California, San Francisco
Merck Sharp & Dohme LLC

Withdrawn

Pembrolizumab With or Without Chemotherapy Before Surgery in Treating Patients With Stage I-IIIA Non-Small Cell Lung Cancer

Lung Non-Small Cell Carcinoma | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage I Lung Cancer AJCC v8 | Stage IA1 Lung Cancer AJCC v8 | Stage IA2 Lung Cancer AJCC v8 | Stage IA3 Lung Cancer AJCC v8 | Stage IB Lung Cancer...

United States
AbbVie

Recruiting

Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (LIVIGNO-4)

Non-Small Cell Lung Cancer

United States, Israel, Japan, Taiwan
Nasser Hanna
Genentech, Inc.

Recruiting

Adjuvant Treatment With Cisplatin-based Chemotherapy Plus Concomitant Atezolizumab in Patients With Stage I (Tumors ≥ 4cm), IIA, IIB, and Select Stage III [Any T1-3 N1-2 and T4N0-2] Resected Non-small Cell Lung Cancer (NSCLC) and the Clearance of Circulating Tumor DNA (ctDNA)

NSCLC | Lung Cancer

United States
Xencor, Inc.

Recruiting

Study of Vudalimab or Pembrolizumab in Combination With Chemotherapy as First-line Treatment in Patients With Advanced NSCLC

Nonsquamous Non-small Cell Lung Cancer

United States
Fuzhou General Hospital

Terminated

Compare Apatinib Plus Chemotherapy Drug Versus Chemotherapy Drug as Second-line Treatment in NSCLC

Nonsmall Cell Lung Cancer

China
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S9717 Tirapazamine Plus Cisplatin in Treating Patients With Metastatic, Recurrent, or Refractory Cervical Cancer

Cervical Cancer

United States
Harbin Medical University

Unknown

Effectiveness and Toxicity of Gemcitabine/Lobaplatin Versus Gemcitabine/Cisplatin as Second-line Treatment in Metastatic Breast Cancer

Breast Cancer

China
Sanofi

Completed

Study Comparing Radiochemotherapy With Folfox 4 Regimen or 5FU-Cisplatin in Patients With Inoperable Esophageal Cancer

Esophageal Neoplasms

France
Shanghai Henlius Biotech

Recruiting

A Phase II Clinical Study to Evaluate the Efficacy and Safety of HLX07 Combination Therapy or Monotherapy in Patients With Advanced ESCC

ESCC or Esophageal Adenosquamous Carcinoma

China
National University Hospital, Singapore

Recruiting

Cisplatin Combined With Oral TS-1 in Patients With Advanced Solid Tumors With Different Degrees of Liver Dysfunction

Cancer | Liver Dysfunction

Singapore
Academisch Medisch Centrum - Universiteit van Amsterdam...

Unknown

Cisplatin Combined With Radiation Therapy and Hyperthermia in Treating Patients With Stage II, Stage III, or Stage IV Cervical Cancer

Cervical Cancer

Netherlands
University of Tennessee
North American Skull Base Society

Withdrawn

Chemoradiotherapy Followed by Surgery for Advanced Paranasal Sinus Cancer

Paranasal Sinus Neoplasms
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

First-line Replacement Maintenance of Envafolimab in Advanced NSCLC (NSCLC)

Non-Small-Cell Lung

China
Gynecologic Oncology Group
National Cancer Institute (NCI); Eli Lilly and Company

Completed

Pemetrexed Disodium in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer

Ovarian Cancer | Primary Peritoneal Cavity Cancer

United States
The University of Texas Health Science Center at...
National Cancer Institute (NCI); Lily Research Laboratories

Completed

LY231514 in Treating Patients With Locally Advanced or Metastatic Solid Tumors and Varying Degrees of Kidney Function

Unspecified Adult Solid Tumor, Protocol Specific

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0423 Pemetrexed Disodium in Treating Patients With Recurrent and Unresectable or Metastatic Chondrosarcoma

Sarcoma

United States
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

Camrelizumab Combined With Pemetrexed and Carboplatin for the Study of EGFR-mutated Lung Squamous NSCLC Treatment

Lung Cancer Stage II
Boehringer Ingelheim

Completed

Trial of BI 6727 (Volasertib) Monotherapy and BI 6727 in Combination With Pemetrexed Compared to Pemetrexed Monotherapy in Advanced NSCLC

Carcinoma, Non-Small-Cell Lung

Bahamas, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Pemetrexed Disodium in Treating Young Patients With Recurrent Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific

United States, Canada
Sun Yat-sen University
Eli Lilly and Company

Completed

Study of Alimta in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC) Who Have Had Prior Platinum Based Chemotherapy

Nasopharyngeal Neoplasms

China
Eli Lilly and Company

Completed

A Study of Pemetrexed and Folic Acid Given Before Surgery (Neoadjuvant Treatment) to Patients With Rectal Cancer.

Rectal Neoplasms

Sweden
Eli Lilly and Company

Completed

Pemetrexed as the First Treatment in Advanced or Metastatic Breast Cancer

Breast Cancer | Breast Neoplasms, Male | Carcinoma, Ductal

United States
Eli Lilly and Company

Completed

Trial of Pemetrexed for Patients With Pancreatic Cancer Which Cannot be Treated With Surgery or is Metastatic

Pancreatic Cancer

Germany
Peking Union Medical College Hospital

Not yet recruiting

A Prospective Study of Pembrolizumab Combining Chemotherapy in Advanced NSCLC Patients With EGFR Exon 21 Point Mutation.

Non Small Cell Lung Cancer | Immune Checkpoint Inhibitor | EGFR Exon 21 Mutation

China
Centre Hospitalier Universitaire de Besancon

Completed

Radiochemotherapy in Elderly Patients With Oesophagus Cancer (Chronos)

Esophagus Cancer
All India Institute of Medical Sciences, New Delhi

Unknown

Accelerated Fractionation Radiotherapy (AFRT) Versus Concurrent Chemoradiotherapy (Crt) In Locally Advanced Head And Neck Squamous Cell Carcinoma

HEAD AND NECK CANCER

India
Lund University Hospital
Sanofi

Completed

A Study of Standard Treatment +/- Enoxaparin in Small Cell Lung Cancer (RASTEN)

Small Cell Lung Cancer

Sweden
AbbVie

Withdrawn

Study of Intravenous Telisotuzumab Vedotin in Combination Osimertinib or Standard of Care Chemotherapy to Assess Change in Disease Activity in Adult Participants With Non-Small Cell Lung Cancer That Has a Mutation in the Epidermal Growth Factor Receptor Gene and That Overexpresses the c-Met Protein

Non-Small Cell Lung Cancer
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Tongji Hospital; Hunan Cancer... and other collaborators

Recruiting

Phase III Trial of Concurrent Chemotherapy Alone in Patients With Low-risk Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Pfizer

Completed

Investigational Agent AG-013736 In Combinations With Standard Of Care Treatments For Patient's With Advanced Solid Tumor

Neoplasms

Poland, United States, Spain
National Cancer Institute (NCI)

Active, not recruiting

Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesothelioma

Epithelioid Mesothelioma | Pleural Malignant Mesothelioma | Sarcomatoid Mesothelioma | Recurrent Malignant Mesothelioma

United States
Eli Lilly and Company

Completed

A Single Arm Phase 2 Study of Pemetrexed as 2nd-Line Treatment of Advanced Non-Small Cell Lung Cancer

Carcinoma, Non-Small Cell Lung

China, Taiwan, Australia, Korea, Republic of, Egypt, Romania, India, Turkey
Eli Lilly and Company

Completed

A Phase 2 Trial of ALIMTA (Pemetrexed) in Locally Advanced or Metastatic Recurrent Transitional Cell Carcinoma of the Urothelium

Urologic Neoplasms | Metastases, Neoplasm

United States
Roswell Park Cancer Institute

Completed

Cisplatin in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer or Lung Metastasis

Stage IIIB Non-Small Cell Lung Cancer | Stage IV Non-Small Cell Lung Cancer | Stage IV Adult Soft Tissue Sarcoma | Metastatic Malignant Neoplasm in the Lung

United States
Centre Oscar Lambret
National Cancer Institute, France

Terminated

Benefit of Chemotherapy Over Best Supportive Care in Metastatic and Squamous Cell-type Esophageal Cancer. (E-DIS)

Squamous Cell Carcinoma of Esophagus

France
Genentech, Inc.

Completed

A Study of Onartuzumab (MetMAb) in Combination With Bevacizumab (Avastin) Plus Platinum And Paclitaxel or With Pemetrexed Plus Platinum in Patients With Non-Squamous Non-Small Cell Lung Cancer

Non-Squamous Non-Small Cell Lung Cancer

Spain, France, United States, Taiwan, United Kingdom, Philippines, Latvia, Italy, Israel, Argentina, Mexico, Germany, Malaysia
Institut du Cancer de Montpellier - Val d'Aurelle

Active, not recruiting

A Phase II Trial Evaluating an Organ-conserving Strategy by Radiochemotherapy for Muscle-infiltrative Bladder Cancer (GETUGV04)

Infiltrating Bladder Urothelial Carcinoma

France
Henan Provincial People's Hospital
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Study of Anlotinib Combined With Pemetrexed in Patients With Advanced Nonsquamous NSCLC (ALTER-L025)

Non-squamous Cell Non-Small Cell Lung Cancer

China

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