Search clinical trials for: Pioglitazone+and+metformin

Total 270079 results

Yonsei University

Unknown

Effect of Adjunctive Metformin on Recurrence of Non-DM Colorectal Cancer Stage II High-risk/ III Colorectal Cancer

Non-DM Stage II High-risk Colorectal Cancer | Non-DM Stage III Colorectal Cancer

Korea, Republic of
Swiss Group for Clinical Cancer Research

Completed

Metformin Hydrochloride as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Prostate Cancer

Prostate Cancer

Switzerland
Massachusetts General Hospital
American Diabetes Association

Unknown

Polycystic Ovary Syndrome Genetics and Treatment Response

Polycystic Ovary Syndrome

United States
University Hospital, Aker
Merck Sharp & Dohme LLC

Unknown

Metformin in Non-Alcoholic Fatty Liver Disease

Fatty Liver

Norway
Anna Stanhewicz, PhD

Not yet recruiting

Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes

Gestational Diabetes
University of Kansas Medical Center

Recruiting

Effects of Metformin on Airway Ion Channel Dysfunction in Cystic Fibrosis-related Diabetes

Cystic Fibrosis | Cystic Fibrosis-related Diabetes

United States
Holland Bloorview Kids Rehabilitation Hospital
The Hospital for Sick Children

Recruiting

Metformin for Motor and Cognitive Improvement in Children With Cerebral Palsy: A Feasibility Study

Cerebral Palsy

Canada
Boston Children's Hospital

Completed

Pilot Study of Metformin for Patients With Fanconi Anemia

Fanconi Anemia

United States
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Efficacy and Safety of SHR3824 in Combination With Metformin in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus

China
VA Office of Research and Development
Oregon Health and Science University

Completed

Metformin and Muscle in Insulin-resistant Older Veterans (M&M)

Prediabetes

United States
Hoffmann-La Roche

Completed

A Study of The Effect of Aleglitazar on Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin

Diabetes Mellitus Type 2

Germany
University of California, San Francisco

Completed

Impact of Genetics on Metformin Pharmacokinetics

Other Conditions That May Be A Focus of Clinical Attention

United States
Mario Negri Institute for Pharmacological Research
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; Humanitas Hospital,...

Recruiting

Study on Trabectedin in Combination With Pioglitazone in Patients Myxoid Liposarcomas With Stable Disease After T Alone. (TRABEPIO)

Liposarcoma, Myxoid | Liposarcoma, Dedifferentiated | Liposarcoma, Round Cell

Italy
Barts & The London NHS Trust
Barts and the London School of Medicine and Dentistry

Completed

Prevention of Metabolic Complications of Glucocorticoid Excess

Iatrogenic Cushing Disease

United Kingdom
Takeda

Terminated

Safety and Efficacy of TAK-559 in Combination With Metformin in Patients With Type 2 Diabetes Mellitus.

Diabetes Mellitus
Duke University

Terminated

Metformin for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) (NAFLD)

Fatty Liver

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study to Assess the Bioequivalence of 2 Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) (50 mg/1,000 mg) With Respect to the Individual Components of Canagliflozin (1 x 100 mg) and Metformin IR Tablets (2 x 1,000 mg) in Healthy Volunteers

Healthy

United States
University of Texas Southwestern Medical Center

Terminated

Pioglitazone as Second-Line in Patients With Metastatic Pancreatic Cancer After Treatment With Gemcitabine

Pancreatic Cancer

United States
Taipei Veterans General Hospital, Taiwan

Unknown

Thiazolidinedione (TZD) on the Diabetic Retinopathy and Nephropathy

Diabetes

Taiwan
University of Rochester

Completed

Preventing Squamous Cell Skin Cancer

Squamous Cell Carcinoma of the Skin
Children's Hospital Medical Center, Cincinnati

Completed

Pioglitazone Therapy of Autoimmune Pulmonary Alveolar Proteinosis Autoimmune Pulmonary Alveolar Proteinosis (PioPAP)

Autoimmune Pulmonary Alveolar Proteinosis

United States
Takeda

Completed

Pioglitazone Tablets Special Drug Use Surveillance "Combined Use of Insulin Products / Long-term Treatment"

Type 2 Diabetes Mellitus
Takeda
Kaiser Permanente; Department of Epidemiology at University of Pennsylvania

Completed

Cohort Study of Pioglitazone and Bladder Cancer in Patients With Type II Diabetes

Diabetes | Bladder Cancer
GlaxoSmithKline

Completed

Study In People With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Argentina, Canada, Peru, Australia, Latvia, Costa Rica, Russian Federation, New Zealand, Colombia, Mexico, Czech Republic, Ecuador
Joseph Calabrese, MD
Takeda Pharmaceuticals North America, Inc.

Completed

Pioglitazone for the Treatment of Major Depressive Disorder Comorbid With Metabolic Syndrome

Depressive Disorder, Major | Metabolic Syndrome X

United States
University of Wisconsin, Madison

Withdrawn

Endometriosis: Immunomodulation

Endometriosis
Paul Beringer

Completed

Effect of Pioglitazone on Inflammation in Cystic Fibrosis

Cystic Fibrosis

United States
The University of Texas Health Science Center at...
Takeda

Completed

Molecular Mechanisms of Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Columbia University

Recruiting

Metformin in Heart Failure Without Diabetes (Met-HeFT)

Heart Failure

United States
Canadian Cancer Trials Group
National Cancer Institute (NCI); ETOP IBCSG Partners Foundation; ICR-CTSU

Completed

A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer

Breast Cancer

United States, Canada, Switzerland, United Kingdom
Shenzhen People's Hospital

Unknown

Effect of Metformin as add-on Therapy on Glycemic Control and Other Outcomes in Type 1 Diabetes

Type 1 Diabetes Mellitus | Metformin

China
Hoffmann-La Roche

Completed

A Study of RO5095932 in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus Type 2

United States
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Monotherapy

Diabetes Mellitus Type 2

Korea, Republic of, China
Boehringer Ingelheim

Completed

Relative Bioavailability of Multiple Oral Doses of BI 187004 and Metformin After Co-administration Compared to Multiple Oral Doses of BI 187004 Alone and Metformin Alone in Healthy Male Subjects

Healthy

Germany
Children's Hospital Los Angeles

Terminated

Metformin and Transient Hyperglycemia

Hyperglycemia | Diabetes Mellitus | Insulin Resistance | Acute Lymphoblastic Leukemia

United States
GlaxoSmithKline

Completed

AVANDAMET Versus Metformin And Sulphonylurea In People With Poorly Controlled Type 2 Diabetes

Non-Insulin-Dependent Diabetes Mellitus

Spain, Germany, Belgium, United Kingdom, Ireland, Netherlands, Italy, France, Mexico, Switzerland, Lithuania
Medical University of Bialystok
Medical Research Agency, Poland

Not yet recruiting

Clinical Trials Evaluating the Effect of Metformin Treatment on Function Endometrium in Women Diagnosed With Idiopathic Infertility (METIN)

Infertility, Female
National University of Ireland, Galway, Ireland
Health Research Board, Ireland; University Hospital of Limerick; University College... and other collaborators

Completed

A Randomized Placebo Controlled Trial of the Effectiveness of Metformin in Addition to Usual Care in the Reduction of Gestational Diabetes Mellitus Effects (EMERGE)

Gestational Diabetes

Ireland
Maria Sandberg Westerstahl

Terminated

Effect of Exercise or Metformin on Nocturnal Blood Pressure and Other Risk Factors for CVD Among Obese Adolescents

Cardiovascular Diseases

Sweden
National Cancer Institute (NCI)

Completed

Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI

Obesity | Colorectal Cancer | Adenomatous Polyp

Canada, United States
Massachusetts General Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Unknown

Metformin Treatment in Polycystic Ovary Syndrome (PCOS)

Polycystic Ovary Syndrome
University of Hawaii
National Institute of General Medical Sciences (NIGMS)

Unknown

Metformin for HIV Inflammation

Coronary Artery Disease | HIV

United States
Torrent Pharmaceuticals Limited

Completed

Study to Evaluate the Bioequivalence of a Test Tablet Formulation of Metformin HCl (1000 mg), Compared to an Equivalent Dose of a Commercially Available Reference Drug Product (Glucophage®, Bristol-Myers Squibb Company) in Fasted, Healthy, Adult Subjects

Healthy

United States
Torrent Pharmaceuticals Limited

Completed

Study to Evaluate the Bioequivalence of a Test Tablet Formulation of Metformin HCl (1000 mg), Compared to an Equivalent Dose of a Commercially Available Reference Drug Product (Glucophage®, Bristol-Myers Squibb Company) in Fed, Healthy, Adult Subjects

Healthy

United States
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Canagliflozin on Liver Inflammation Damage in Type 2 Diabetes Patients With Nonalcoholic Fatty Liver Disease

Type 2 Diabetes Mellitus With Complication
Cairo University

Recruiting

Efficacy and Safety of Dapagliflozin in Patients With Non-alcoholic Steatohepatitis

Non-alcoholic Steatohepatitis

Egypt
Getz Pharma

Recruiting

Effect of Oral Anti-diabetic Medication on Liver Fat in Subjects With Type II Diabetes and Non-alcoholic Fatty Liver

Diabetes Mellitus, Type 2 | NAFLD | NASH - Nonalcoholic Steatohepatitis

Pakistan
Peking University Third Hospital

Completed

Effect of Metformin on Patients With Polycystic Ovary Syndrome

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries

China
Fudan University

Recruiting

Metformin and Insulin to Pancreatic Cancer Related Diabetes (Type 3c)

Diabete Mellitus | Pancretic Cancer

China
Lille Catholic University
Centre Hospitalier Arras

Recruiting

Impact of Metformin on Leptin Transport in Cerebrospinal Fluid of Obese Patients (LEPTOB)

Obesity Without Type 2 Diabetes, With BMI>30

France

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