Search clinical trials for: Placebo - Solution

Total 68360 results

Centre Hospitalier Universitaire Vaudois

Recruiting

Exploring the Effect of Lactate Administration After Ischemic Stroke on Brain Metabolism (LacAVC)

Stroke, Acute

Switzerland
Novartis Pharmaceuticals

Active, not recruiting

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia (ORION-13)

Familial Hypercholesterolemia - Homozygous

Greece, Lebanon, Turkey, France, Canada, Malaysia, Netherlands, United States
The Medicines Company

Completed

Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol (ORION-10)

Elevated Cholesterol | ASCVD

United States
Artery Therapeutics, Inc.
National Institute on Aging (NIA)

Recruiting

Safety and Pharmacokinetics of Single Ascending Doses and Multiple Ascending Doses of CS6253 in Healthy Volunteers

Alzheimer's Disease

Spain
Novartis Pharmaceuticals

Active, not recruiting

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Heterozygous Familial Hypercholesterolemia (ORION-16)

Familial Hypercholesterolemia - Heterozygous

United States, Germany, South Africa, Greece, Italy, Czechia, Taiwan, Slovakia, Turkey, France, Russian Federation, Canada, Spain, Jordan, Switzerland, Hungary, Poland, Netherlands, Norway, United Kingdom, Lebanon, Argentina, Brazil, ... and more
Vicore Pharma AB

Completed

First-in-human Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of C106 in Healthy Subjects

Idiopathic Pulmonary Fibrosis | Pulmonary Hypertension | Tolerance | Safety Issues

Sweden
Jazz Pharmaceuticals

Completed

A Multicenter Study of the Efficacy and Safety of JZP-258 in the Treatment of Idiopathic Hypersomnia (IH) With an Open-label Safety Extension

Idiopathic Hypersomnia

France, Spain, United States, Belgium, United Kingdom, Poland, Czechia, Finland
Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories...
Attikon Hospital

Terminated

Triiodothyronine for the Treatment of Critically Ill Patients With COVID-19 Infection (Thy-Support)

Covid-19 | Pulmonary Infection

Greece
Spyryx Biosciences, Inc.

Completed

An Efficacy and Safety Study of SPX-101 Inhalation Solution in Subjects With Cystic Fibrosis ((HOPE-1))

Cystic Fibrosis

United Kingdom, Canada, France, Italy, Portugal
Centers for Disease Control and Prevention, China
Beijing Ditan Hospital; National Institutes for Food and Drug Control, China

Unknown

Clinical Trial of Recombinant Adenovirus Type 5 AIDS Vaccine

Acquired Immunodeficiency Syndrome

China
Bausch & Lomb Incorporated

Completed

Safety and Efficacy Study of Vitrase for Clearance of Severe Vitreous Hemorrhage

Diabetic Retinopathy | Vitreous Hemorrhage

Spain, Australia, United Kingdom, Brazil, Hungary, Italy, Netherlands, Poland, South Africa
Maastricht University Medical Center

Completed

Microvascular Dilatation After Endogenous Induced Hyperinsulinemia

Hypertension | Obesity

Netherlands
Richard W Yee, MD
Novartis Pharmaceuticals

Recruiting

The Effects and Safety of 5% Lifitegrast Ophthalmic Solution in Subjects With Dry Eye Disease in Ocular Graft-versus-Host Disease

Graft-versus-host-disease | Ocular Graft-versus-host Disease

United States
Aldeyra Therapeutics, Inc.

Completed

A Multi-Center, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Clinical Trial Evaluating the Safety of Reproxalap Ophthalmic Solution in Subjects With Dry Eye Disease

Dry Eye Disease

United States
Mitotech, SA
ORA, Inc.

Completed

A Clinical Study to Assess the Safety and Efficacy of an Ophthalmic Solution (SkQ1) in the Treatment of Dry Eye Syndrome (DES)

Keratoconjunctivitis Sicca

United States
United Therapeutics

Terminated

A Phase 3 Adaptive Study to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Participants With Pulmonary Hypertension (PH) Due to Chronic Obstructive Pulmonary Disease (COPD) (PERFECT)

Chronic Obstructive Pulmonary Disease | Pulmonary Hypertension

United States, Israel, Argentina, Puerto Rico
GlaxoSmithKline
Clinical Unit at Cambridge (Addenbrooks)

Completed

A Safety and Tolerability Study of GSK2982772, in Single (in Both Fed and Fasted States) and Repeat Oral Doses in Healthy Male Subjects

Inflammatory Bowel Diseases

United Kingdom
Aires Pharmaceuticals, Inc.

Completed

Dose-Finding, Safety, Pharmacodynamic Effect Study of Sodium Nitrite Inhalation Solution in Normal, Healthy Volunteers (AIR001-CS02)

Pulmonary Arterial Hypertension

United States
Senju Pharmaceutical Co., Ltd.

Completed

Safety and Efficacy of SJP-0035 Ophthalmic Solution in Patients With Moderate to Severe Corneal Epithelial Disorders

Corneal Epithelial Disorders

United States
Topivert Pharma Ltd

Completed

Study of TOP1630 for Dry Eye Syndrome (THEIA-1)

Dry Eye Syndrome

United States
Chengdu SciMount Pharmatech Co., Ltd.

Completed

A Phase 1 Study of SMP-100 in Normal Healthy Volunteers

Healthy Volunteers

Australia
National University Hospital, Singapore

Unknown

Effects of Probiotics in Preventing Oral Mucositis

Head-and-neck Cancer

Singapore
ASIT Biotech S.A.

Unknown

Clinical Efficacy and Safety of Subcutaneous Immunotherapy With gpASIT+™ in Patients With Grass Pollen-induced Allergic Rhinoconjunctivitis

Hay Fever
Octapharma

Terminated

Safety and Efficacy Study of Three Different Dosages of NewGam in Patients With CIDP (POINT)

Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Unilever R&D

Completed

The Effect of a Natural Extract on Glucose Fluxes After Consumption of a Wheat Product

Healthy

Netherlands
NYU Langone Health
Naurex, Inc, an affiliate of Allergan plc

Withdrawn

NRX-1074 in Early Course Schizophrenia

Schizophrenia

United States
St. Justine's Hospital
Canadian Association of Emergency Physicians

Completed

Effect on Pain of Oral Sucrose Versus Placebo in Children 1 to 3 Months Old Needing Venipuncture

Pain

Canada
St. Justine's Hospital

Completed

Trial of an Oral Sucrose Solution Versus Placebo in Children 1 to 3 Months Old Needing Bladder Catheterization

Pain

Canada
Ospedale Misericordia e Dolce

Completed

Hydration and Contrast-Induced Nephropathy in Primary Angioplasty

Contrast Induced Nephropathy

Italy
TorreyPines Therapeutics

Completed

A Safety Tolerance and Experimental Hyperalgesia Study of Oral NGX426 in Healthy Male Voluneteers

Healthy | Hyperalgesia

United States
Laureate Institute for Brain Research, Inc.

Completed

Lipopolysaccharide (LPS) Challenge in Depression

Major Depressive Disorder

United States
Bugworks Research Inc.
Avance Clinical Pty Ltd.

Completed

A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of BWC0977 in Healthy Volunteers

Bacterial Infections | Infectious Diseases

Australia
Mansoura University

Active, not recruiting

A Randomized Controlled Trial to Investigate The Role of Adjuvant Inhalable Sodium Bicarbonate Solution 8.4% in Treatment of COVID-19

Covid19 | COVID-19 Pneumonia | COVID-19 Acute Respiratory Distress Syndrome

Egypt
Daiichi Sankyo Co., Ltd.

Completed

Safety of DS-1040b in Acute Ischemic Stroke Patients Treated With Thrombectomy

Acute Ischemic Stroke

Japan
University of Pennsylvania

Completed

GLP 1 for Intraoperative Glycemic Control (GLP)

Hyperglycemia | Hypoglycemia

United States
Boehringer Ingelheim

Recruiting

A Study to Test Whether Spesolimab Helps People With a Skin Disease Called Netherton Syndrome

Netherton Syndrome

Belgium, United Kingdom, Australia, Germany, China, Malaysia, Japan, France, United States, Israel, Bulgaria, Italy, Switzerland, Austria, Netherlands, Portugal
Jonsson Comprehensive Cancer Center

Withdrawn

Bimatoprost Ophthalmic Solution in Increasing Eyebrow and Eyelash Growth in Patients Who Have Undergone Chemotherapy for Breast Cancer and in Healthy Participants

Breast Cancer | Alopecia

United States
Qlaris Bio, Inc.

Not yet recruiting

Qlaris Phase 2 Study in NTG Patients

Glaucoma | Normal Tension Glaucoma (NTG) | Low-Tension Glaucoma, Bilateral | Low-Tension Glaucoma, Unspecified Eye

Korea, Republic of, Philippines
Wakayama Medical University
Epidemiological and Clinical Research Information Network

Unknown

Daikenchuto for Intestinal Dysmotility and Prevention of Postoperative Paralytic Ielus After Pancreaticoduodenectomy (JAPAN-PD)

Paralytic Ileus

Japan
RDC Clinical Pty Ltd

Not yet recruiting

Effect of Topical PlexoZome® Levagen® Spray on Relief of Post Exercise Knee Joint Pain

Knee Joint Pain

Australia
AstraZeneca

Completed

Single + Multiple Ascending Dose and Food Effect Study of AZD7986 in Healthy Volunteers, PK, PD and Safety Study

Safety, Pharmacokinetics, Pharmacodynamics, Food Effect

United Kingdom
Prof. Dr. Jörg Leuppi

Terminated

Inhaled Aviptadil for the Treatment of COVID-19 in Patients at High Risk for ARDS

Covid19 | Corona Virus Infection | ARDS | Aviptadil

Switzerland
Supergene, LLC
Russian Academy of Medical Sciences

Terminated

Inhaled Recombinant Non-immunogenic Staphylokinase vs Placebo in Patients With COVID-19 - FORRIF Trial (FORRIF)

COVID-19

Russian Federation
Bioverativ, a Sanofi company
Assign Data Management and Biostatistics GmbH; Quest Diagnostics-Nichols Insitute and other collaborators

Completed

Safety, Tolerability and Activity of BIVV009 in Healthy Volunteers and Patients With Complement Mediated Disorders (BIVV009-01)

End-stage Renal Disease (ESRD) | Cold Agglutinin Disease (CAD) | Bullous Pemphigoid (BP) | Warm Autoimmune Hemolytic Anemia (WAIHA)

Austria
Merck Sharp & Dohme LLC

Completed

Study of Denufosol Tetrasodium Inhalation Solution in Patients With Cystic Fibrosis (CF) Lung Disease

Cystic Fibrosis

United States, Australia, Canada, New Zealand
AstraZeneca

Completed

Study to Investigate the Safety Profile of AZD4721 After Single Doses at Different Dose Levels

Safety,Plasma AUC and Cmax, Plasma AUC 0-t, t1/2λz, and Tmax

United Kingdom
Boehringer Ingelheim

Completed

Dose Extension Study of BIIX 1 XX in Healthy Young Male Volunteers

Healthy
Karamanoğlu Mehmetbey University

Completed

Quality of Recovery in Parturients Consumed Preoperative Carbohydrate Fluid for Elective Cesarean Delivery (QoR-10)

Quality of Life | Postoperative Pain | Breastfeeding | Postoperative Nausea

Turkey
Stealth BioTherapeutics Inc.

Completed

A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for the Treatment of Fuchs' Corneal Endothelial Dystrophy (FCED) (SPIFD-101)

Fuchs' Corneal Endothelial Dystrophy (FCED)

United States
University of Illinois at Chicago

Completed

Hydration Dynamics and Influence of Beverage Composition

Dehydration | Hydration | Fluid Retention

United States

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