Search clinical trials for: Placebo Niacin

Total 53789 results

University of Pennsylvania

Completed

The Genetics of Evoked Responses to Niacin and Endotoxemia: The GENE Study (GENE)

Healthy Volunteers

United States
Eunice Kennedy Shriver National Institute of Child...

Terminated

Free Fatty Acids, Body Weight, and Growth Hormones Secretion in Children

Obesity | Growth Hormone Deficiency | Short Stature

United States
Lewai Sharki Abdulaziz, MSc PhD
Al-Kindy College of Medicine

Completed

Extended Release Niacin and Fenofibrate for the Treatment of Atherogenic Dyslipidemia in Obese Females

Atherogenic Dyslipidemia | Obesity Associated Disorder

Iraq
Iowa State University

Completed

Effects of Nicotinamide Riboside on Metabolism and Vascular Function

Aging | Lipemia

United States
ChromaDex, Inc.
Midwest Center for Metabolic and Cardiovascular Research

Completed

A Study by ChromaDex to Assess the Effects of TRU NIAGEN on Cognitive Function, Mood and Sleep in Older Adults

Sleep | Cognitive Function | Mood

United States
Franklin Health Research

Active, not recruiting

IV Administration of ChromaDex's Niagen® as Compared to NAD+

Healthy Aging

United States
Organon and Co

Completed

To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia (0653A-091)(COMPLETED)

Hypercholesterolemia
University of Pennsylvania

Completed

Assessment Of Vascular Health After Niacin Therapy (AVANT) (AVANT)

Coronary Artery Disease | Peripheral Artery Disease | Carotid Artery Disease

United States
Donna Hammond, PhD

Active, not recruiting

NIAGEN and Persistent Chemotherapy-Induced Peripheral Neuropathy

Chemotherapy-induced Peripheral Neuropathy

United States
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Effects of Extended Release (ER) Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites in Subjects With High Cholesterol (0524A-075)(COMPLETED)

Hypercholesterolemia
Merck Sharp & Dohme LLC

Completed

Extended Niacin/Laropiprant in Patients With Type 2 Diabetes (0524A-069)

Diabetes Mellitus Type 2
Haukeland University Hospital

Recruiting

N-DOSE: A Dose Optimization Trial of Nicotinamide Riboside in Parkinson's Disease

Parkinson Disease

Norway
University of California, Davis

Not yet recruiting

Milk Volume Outcomes Following Oral Nicotinamide Riboside Supplementation in Mothers of Extremely Preterm Infants (MOONRISE)

Preterm Birth | Inadequate Milk Production
Haukeland University Hospital

Completed

NR-SAFE: Safety of High-dose Nicotinamide Riboside (NR) in Parkinson's Disease (NR-SAFE)

Parkinson Disease

Norway
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Effects of ER Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites (0524A-079)(COMPLETED)

Type 2 Diabetes Mellitus
Oriflame Cosmetics AB

Completed

Facial Skin Clinical and Microbial Profiling From Oral Probiotic Supplementation

Healthy | Skin Manifestations

Sweden
Merck Sharp & Dohme LLC

Completed

A Long-term Study of ERN/LRPT (Extended Release Niacin/Laropiprant [MK0524A]) in Patients With Dyslipidemia (0524A-102)

Dyslipidemia
The University of Texas Health Science Center at...
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Nicotinamide Riboside in SARS-CoV-2 (COVID-19) Patients for Renal Protection (NIRVANA)

Acute Kidney Injury | SARS-CoV-2 Infection

United States
University of Washington
National Heart, Lung, and Blood Institute (NHLBI); Pfizer; Daiichi Sankyo, Inc.; Abbo... and other collaborators

Completed

Evaluate Carotid Artery Plaque Composition by Magnetic Resonance Imaging in People Receiving Cholesterol Medication (CPC)

Coronary Artery Disease | Atherosclerosis | Carotid Artery Diseases

United States
University of Washington
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Nicotinamide Riboside in Systolic Heart Failure

Heart Failure, Systolic

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

Obesity | Psoriasis | Dyslipidemia | Atherosclerotic Cardiovascular Disease | Cardiometabolic Diseases

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Niacin Therapy on Lipoprotein Composition and Function

Cardiovascular Disease

United States
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI); Arizona Pharmaceuticals...

Completed

Effects of Niacin On Fatty Acid Trapping (NOFAT)

Dyslipidemia

United States
University Medical Centre Ljubljana

Completed

Niacin/Laropiprant and Endothelial Function

Coronary Heart Disease

Slovenia
Calmy Alexandra
University Hospital, Geneva; Swiss National Science Foundation; Swiss Heart Foundation and other collaborators

Terminated

ER Niacin/Laropiprant Impact on Cardiovascular Markers and Atheroprogression in HIV-infected Individuals on cART (NILACH)

Atherosclerosis | HIV

Switzerland
Dexa Medica Group

Completed

Efficacy and Safety of DLBS3233 in Prediabetic Patients (DIPPER-DM)

Prediabetic

Indonesia
Maastricht University Medical Center
Dutch Heart Foundation

Completed

Nicotinamide Riboside and Metabolic Health

Obesity | Insulin Resistance

Netherlands
Dexa Medica Group

Completed

Efficacy and Safety of DLBS3233 in Subjects With New Onset of Type 2 Diabetes Mellitus

Type-2-diabetes Mellitus | New Onset

Indonesia
George Thanassoulis
Jewish General Hospital; Laval University; Quebec Heart Institute

Withdrawn

Early Aortic Valve Lipoprotein(a) Lowering Trial (EAVaLL)

Aortic Stenosis and Lipoprotein(a) Levels

Canada
Mayo Clinic
University of Minnesota; Thorne Research Inc.

Completed

Use of 31P MRS to Assess Brain NAD+ in Healthy Current and Former Collegiate Athletes (TRMC-004)

Concussion, Mild

United States
University of Pennsylvania
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effect of Niacin on Transport of HDL and Relationship to Atherogenic Lipoproteins and Lipolysis (ENTHRALL)

Dyslipidemias

United States
University of Miami

Terminated

Study of the Use of Niaspan for Treatment of Dyslipidemia in Diabetic Nephropathy

Diabetes Mellitus, Type 2 | Kidney Failure, Chronic | Hyperlipidemia

United States
Merck Sharp & Dohme LLC

Completed

Effect of an Investigational Compound on Tolerability of Extended Release Niacin (0524A-023)(COMPLETED)

Hyperlipidemia | Hypercholesteremia
Merck Sharp & Dohme LLC

Withdrawn

Extended Release (ER) Niacin/Laropiprant Add on Study (0524A-082)

Dyslipidemia
Daniel A. Siniawski
Merck Sharp & Dohme LLC

Terminated

Lipid Efficacy of the Extended Release Niacin/Laropiprant Combination in Patients With Cardiovascular Disease

Coronary Artery Disease | Dyslipidemias

Argentina
University Hospital, Akershus
Norwegian Cancer Society; Helse Sor-Ost; ChromaDex, Inc.; Norwegian Breast Cancer...

Recruiting

Nicotinamide Riboside and Prevention of Cancer Therapy Related Cardiac Dysfunction in Breast Cancer Patients (NARNIA)

Heart Failure | Breast Cancer | Metastatic Breast Cancer | Cardiotoxicity | Cancer Therapy-Related Cardiac Dysfunction

Norway
Aarhus University Hospital
University of Copenhagen

Completed

The Effect of Vitamin B3 on Substrate Metabolism, Insulin Sensitivity, and Body Composition in Obese Men

Obese

Denmark
University of Bath

Recruiting

Glycogen and Appetite

Energy Intake

United Kingdom
VA Office of Research and Development

Completed

GPR109A and Parkinson's Disease: Role of Niacin in Outcome Measures

Parkinson's Disease

United States
Merck Sharp & Dohme LLC

Completed

An Investigational Drug Study Evaluating a Novel Approach to Treat Dyslipidemia (0524A-032)

Dyslipidemia
Merck Sharp & Dohme LLC

Terminated

Carotid IMT (Intima Media Thickening) Study (0524A-041)(TERMINATED) (ACHIEVE)

Hypercholesterolemia, Familial
Merck Sharp & Dohme LLC

Completed

Tolerability of MK0524A Versus Niacin Extended-Release (0524A-054)

Hypercholesterolemia | Hyperlipidemia
University of California, San Diego

Recruiting

Psilocybin-assisted Therapy for Phantom Limb Pain

Phantom Limb Pain

United States
Merck Sharp & Dohme LLC

Completed

Effect of MK0524A on Cholesterol Levels (0524A-048)

Hypercholesterolemia | Hyperlipidemia
Bayside Health
National Health and Medical Research Council, Australia

Terminated

Effects of Niacin on Good Cholesterol in People With Peripheral Arterial Disease

Peripheral Arterial Disease

Australia
Hannover Medical School

Completed

The High Density Lipoprotein and Endothelial Function, Niacin and Nitric Oxide Study (The High-Ennd Study)

Metabolic Syndrome

Germany
Acura Pharmaceuticals Inc.

Completed

Safety/Efficacy Study of Oxycodone HCl/Niacin to Treat Pain After Bunionectomy

Pain
Charite University, Berlin, Germany

Unknown

Evaluation of the Effect of NICOtinic Acid (Niacin) on Elevated Lipoprotein(a) Levels (NICOLa Study) (NICOLa)

Elevated Lipoprotein(a) Levels

Germany
Merck Sharp & Dohme LLC

Terminated

Efficacy and Safety of Extended Release (ER) Niacin/Laropiprant When Added to Ongoing Lipid-Modifying Therapy in Patients With High Cholesterol or Abnormal Lipid Levels (MK-0524A-133)

Mixed Dyslipidemia | Primary Hypercholesterolemia
Merck Sharp & Dohme LLC

Completed

MK0524A Phase IIb Study (0524A-011)(COMPLETED)

Flushing

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