Search clinical trials for: Placebo to sitagliptin

Total 60661 results

Woman's
Merck Sharp & Dohme LLC

Completed

Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM

Disorder of Glucose Regulation

United States
Profil Institut für Stoffwechselforschung GmbH
Merck Sharp & Dohme LLC

Completed

Sitagliptin and the Risk for Hypoglycaemia in Type 2 Diabetes Patients

Pharmacological Action

Germany
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Effect of Dipeptidyl Peptidase 4 Inhibition on Growth Hormone Secretion in Women With Polycystic Ovarian Syndrome

Polycystic Ovary Syndrome

United States
Novo Nordisk A/S

Completed

Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin and/or TZD in Subjects With Type 2 Diabetes (SUSTAIN™ 2)

Diabetes Mellitus, Type 2 | Diabetes

India, Japan, Russian Federation, Spain, Sweden, Argentina, Hungary, Norway, South Africa, Turkey, Bulgaria, Romania, Thailand, Portugal, Hong Kong, Mexico, Ukraine, Czechia
Ingrid Jazet
Merck Sharp & Dohme LLC

Completed

Sitagliptin and Brown Adipose Tissue (Sita01)

Neoplasms, Adipose Tissue

Netherlands
Washington University School of Medicine

Completed

Effectiveness of Sitagliptin for HIV Insulin Resistance and Inflammation

Inflammation | Cardiovascular Disease | Macrophage Infiltration

United States
University Health Network, Toronto
Merck Frosst Canada Ltd.

Completed

Sitagliptin Regulation of Intestinal and Hepatic Lipoprotein Particle and Hepatic Glucose Production in Humans

Hyperlipidemia

Canada
Research Clinical Centre of the Russian Railways...

Unknown

Glucose Variability With DPP-4 Inhibition

Type 2 Diabetes
HighTide Biopharma Pty Ltd

Completed

A Multiple Ascending Dose Study of HTD1801 in Adults With Hypercholesterolemia

Hypercholesterolemia

Australia
Merck Sharp & Dohme LLC

Completed

A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Concomitant Administration of Sitagliptin and Metformin as Individual Tablets (0431A-048)

Type 2 Diabetes
Merck Sharp & Dohme LLC

Completed

Bioequivalence Study of Sitagliptin/Metformin Combination Tablet (MK0431A-122)

Type 2 Diabetes
Merck Sharp & Dohme LLC

Completed

Study of Grazoprevir (MK-5172) and Elbasvir (MK-8742) in Japanese Participants With Chronic Hepatitis C (MK-5172-058)

Hepatitis C
Novo Nordisk A/S

Completed

Efficacy and Long-term Safety of Oral Semaglutide Versus Sitagliptin in Subjects With Type 2 Diabetes (PIONEER 3)

Diabetes Mellitus, Type 2 | Diabetes

United States, India, Israel, Japan, Russian Federation, United Kingdom, France, Mexico, South Africa, Turkey, Argentina, Germany, Romania, Brazil, Ukraine
University of Pennsylvania
Children's Hospital of Philadelphia

Completed

Effect of Chronic Incretin-based Therapy in Cystic Fibrosis

Cystic Fibrosis | Pancreatic Insufficiency

United States
Dong-A ST Co., Ltd.

Completed

A Study to Evaluate the Safety, Tolerability, PK and PD of DA-1241 in Healthy Male Subjects and Subjects With T2DM

Diabetes Mellitus, Type 2

United States
Novartis Pharmaceuticals

Completed

Clinical Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LEZ763

Type II Diabetes

United States
Blandine Laferrere
Merck Sharp & Dohme LLC

Completed

Treatment of Diabetes After Gastric Bypass With Sitagliptin (LAF33)

Type 2 Diabetes Mellitus

United States
Kathleen Dungan

Terminated

Use of Sitagliptin for Stress Hyperglycemia or Mild Diabetes Following Cardiac Surgery

Hyperglycemia | Diabetes Mellitus, Type 2

United States
University of Missouri-Columbia

Terminated

Use of Sitagliptin to Decrease Microalbuminuria

Type 2 Diabetes | Microalbuminuria

United States
Lund University

Completed

Effects of Dipeptidyl Peptidase-4 (DPP-4) Inhibition on Hormonal Responses to Macronutrient Ingestion

Healthy | Type 2 Diabetes

Sweden
University of Oslo School of Pharmacy
Oslo University Hospital

Completed

Sitagliptin in Renal Transplant Recipients

Glucose Intolerance

Norway
Kowa Research Institute, Inc.

Completed

A Study Comparing the Safety, Tolerance, and Efficacy of Various Doses of SK-0403 Versus Placebo and Sitagliptin 100 mg in Patients Not Well-Controlled on Metformin Therapy

Type 2 Diabetes

United States
Hannover Medical School

Unknown

Vascular Effects of Sitagliptin in Diabetes Mellitus

Type 2 Diabetes Mellitus

Germany
Phenomix
Forest Laboratories

Terminated

Study to Evaluate Safety and Efficacy of Dutogliptin in Type 2 Diabetes Mellitus Subjects With Moderate and Severe Renal Impairment

Type 2 Diabetes Mellitus | Renal Impairment

United States, Russian Federation, Ukraine
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

Clinical Study of Retagliptin Phosphate Combined With Metformin in the Treatment of Type 2 Diabetes

Type 2 Diabetes

China
Cerecin

Completed

Tricaprilin in Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

United States
Cerecin

Completed

Tricaprilin In Age-Associated Memory Impairment

Age-Associated Memory Impairment

United States
SIGA Technologies
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase I, Escalating, Multiple-Dose, ST-246 Safety, Tolerability and Pharmacokinetics 21-Day Trial in Healthy Volunteers (SIGA-246-002)

Healthy

United States
Second Affiliated Hospital of Soochow University

Unknown

Evaluation of the Effect of Sitagliptin on Gut Microbiota in Patients With Newly Diagnosed Type 2 Diabetes

Type 2 Diabetes
University Hospital, Gentofte, Copenhagen

Completed

GA 6: The Blood Glucose-lowering Effect of Glucose-dependent Insulinotropic Polypeptide

Type2 Diabetes

Denmark
Merck Sharp & Dohme LLC

Recruiting

Safety and Pharmacokinetic Study of Oral MK-8527 QM in Participants at Low-Risk for HIV-1 Infection (MK-8527-007)

HIV | HIV Pre-exposure Prophylaxis

United States, South Africa, Israel
GlaxoSmithKline

Recruiting

Study of GSK3965193 in Healthy Participants and Participants Living With Chronic Hepatitis B Infection

Hepatitis B

United Kingdom
Merck Sharp & Dohme LLC

Completed

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MK-3281 in Healthy and Hepatitis C Infected Male Participants (MK-3281-002)

Hepatitis C
GlaxoSmithKline

Completed

A Clinical Study to Assess Single and Repeat Doses of a New Medication (GSK933776) in Patients With Alzheimer's Disease

Alzheimer's Disease

Australia, Sweden, Norway
Boehringer Ingelheim

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Ascending Oral Doses and Effect of Food on the Bioavailability of BI 1060469

Healthy

Germany
Eli Lilly and Company
Berry Consultants; United BioSource, LLC; Tessella Inc.

Completed

A Study of LY2189265 Compared to Sitagliptin in Participants With Type 2 Diabetes Mellitus on Metformin

Diabetes Mellitus, Type 2

United States, Korea, Republic of, Russian Federation, Puerto Rico, Romania, Spain, Taiwan, Mexico, France, Germany, India, Canada, Poland
Boehringer Ingelheim

Completed

To Assess Safety, Tolerability and Pharmacokinetics of BI 416970 in Healthy Male Volunteers

Healthy

Germany
Merck Sharp & Dohme LLC

Completed

A Study of V950 in People With Alzheimer Disease (V950-001 AM7)

Alzheimer Disease
Merck Sharp & Dohme LLC

Completed

Safety, Pharmacokinetics, and Pharmacodynamics of MK-6325 in Hepatitis C Virus (HCV) Infections (MK-6325-003)

Hepatitis C
Boehringer Ingelheim

Completed

Safety and Pharmacokinetics of Single Rising Oral Doses of BI 224436 ZW in Healthy Male Volunteers.

Healthy
Novartis

Completed

Efficacy and Safety of Once Daily Dosing of Aliskiren (300 mg (qd) Once a Day) to Twice Daily Dosing of Aliskiren (150 mg (Bid) Twice a Day) in Treating Moderate Hypertension.

Essential Hypertension

Germany, Spain, United States
Albert Einstein College of Medicine

Completed

Sitagliptin Dose Determination Study

Diabetes Mellitus, Type 1

United States
Merck Sharp & Dohme LLC

Completed

Study of Sitagliptin in Older Type 2 Diabetics (0431-047)(COMPLETED)

Type 2 Diabetes
CymaBay Therapeutics, Inc.

Completed

Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of MBX-2982 Administered Daily for 4 Weeks as Monotherapy in Patients With Type 2 Diabetes

Diabetes

United States, Georgia, India
Academisch Medisch Centrum - Universiteit van Amsterdam...
Merck Sharp & Dohme LLC

Completed

Dipeptidyl Peptidase-4 Inhibitors and Alpha-cell Recovery (DARE)

Hypoglycemia | Type 1 Diabetes

Netherlands
Novartis Pharmaceuticals

Completed

A 12 Week Study in Patients With Type 2 Diabetes Mellitus (T2DM)

Type 2 Diabetes Mellitus

Canada, United States, Italy, Poland, Puerto Rico
Ono Pharmaceutical Co. Ltd

Completed

Controlled Study of MK-0431/ONO-5435 in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Japan
Beijing Chao Yang Hospital

Recruiting

Sitagliptin in Combination With Beidougen Capsule for Type 2 Diabetes

Type 2 Diabetes

China
Novaremed Ltd.

Completed

Effect of NRD135S.E1 in Peripheral Neuropathic Pain in Diabetic Patients

Diabetic Peripheral Neuropathic Pain

Israel
Bionorica SE

Completed

Efficacy and Safety of a Herbal Medicinal Product (Dry Extract BNO 1016) in Patients With Acute Rhinosinusitis

Acute Rhinosinusitis

Germany

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