Search clinical trials for: Placebo + Methotrexate

Total 55005 results

Memorial Sloan Kettering Cancer Center

Completed

LSA4 Protocol for the Treatment of Advanced Pediatric and Adolescent Non-Hodgkins Lymphoma

Non-Hodgkin's Lymphoma

United States
Nanfang Hospital of Southern Medical University

Unknown

PTCy-ATG vs ATG in Haploidentical HSCT for Acute Graft-versus-host Disease Prophylaxis

Hematopoietic Stem Cell Transplantation

China
University of Texas Southwestern Medical Center

Withdrawn

Vaccine Therapy and GM-CSF in Treating Patients With CNS Lymphoma

Lymphoma | Small Intestine Cancer | Brain and Central Nervous System Tumors | Lymphoproliferative Disorder

United States
Japan Biological Agent Study Integrated Consortium

Completed

Efficacy and Safety of Etanercept in Active RA Despite Methotrexate Therapy in Japan (JESMR)

Rheumatoid Arthritis

Japan
University Hospital Freiburg
University Hospital Tuebingen

Unknown

Freiburg ZNS-NHL Study

Primary Non Hodgkin Lymphoma of the Central Nervous System

Germany
Amgen

Completed

Brodalumab (AMG 827) in Rheumatoid Arthritis (RA) Participants With Inadequate Response to Methotrexate

Rheumatoid Arthritis
University of Leeds
Abbott

Completed

ADalimumab in Persistent Early Oligoarthrits Study (ADEOS) (ADEOS)

Oligoarthritis

United Kingdom
Janssen Research & Development, LLC

Terminated

A Dose Range Finding Study of JNJ-38518168 in Patients With Active Rheumatoid Arthritis in Spite of Treatment With Methotrexate

Rheumatoid Arthritis

Poland, Ukraine, Taiwan, United States, Colombia, Mexico, Japan, Korea, Republic of, Russian Federation, Argentina, Chile, Thailand, Hungary, Romania, Czechia, Latvia
Sanofi
Regeneron Pharmaceuticals

Completed

Evaluation of Sarilumab (SAR153191/REGN88) on Top of Methotrexate in Rheumatoid Arthritis Patients (RA-MOBILITY)

Rheumatoid Arthritis

Germany, Hungary, Belgium, United States, Argentina, Australia, Austria, Belarus, Brazil, Canada, Chile, Czechia, Estonia, Finland, Greece, Korea, Republic of, Lithuania, Malaysia, Mexico, New Zealand, Philippines, Poland, Romania, Russian... and more
Bankole Johnson
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Pharmacological Treatment for Alcoholism

Alcohol Dependence

United States
Genentech, Inc.
Roche Pharma AG

Terminated

A Study of Ocrelizumab in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Are Naive to Methotrexate (FILM) (FILM)

Rheumatoid Arthritis
Eli Lilly and Company

Completed

Oral Baricitinib (LY3009104)Treatment in Japanese Participants With Active Rheumatoid Arthritis on Background Methotrexate Therapy

Arthritis, Rheumatoid

Japan
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Completed

Abatacept Post-marketing Clinical Study in Japan

Rheumatoid Arthritis

Japan
Janssen Research & Development, LLC
Schering-Plough

Terminated

A Study of the Safety and Efficacy of CNTO 148 (Golimumab) in Children With Juvenile Idiopathic Arthritis (JIA) and Multiple Joint Involvement Who Have Poor Response to Methotrexate (GO KIDS)

Juvenile Idiopathic Arthritis

Poland, United States, Germany, Belgium, Canada, Finland, Netherlands, Russian Federation, Brazil, Austria, Lithuania, Mexico
Eli Lilly and Company
Incyte Corporation

Completed

A Study in Participants With Rheumatoid Arthritis on Background Methotrexate Therapy

Arthritis, Rheumatoid

Hungary, Romania, United States, Czechia, Croatia, Poland, Ukraine, Mexico, India
Swedish Orphan Biovitrum
Amgen

Completed

Trial to Evaluate Palifermin in the Reduction of Acute Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Allogeneic Marrow/Peripheral Blood Progenitor Cell (PBPC) Transplantation

Hematologic Malignancies | Graft Versus Host Disease
Centocor, Inc.
Schering-Plough

Completed

A Study of Safety and Effectiveness of Golimumab in Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy

Rheumatoid Arthritis

Australia, Poland, Ukraine, United States, Argentina, Colombia, New Zealand, Peru, Mexico, Germany, Hungary, Lithuania, Malaysia, Latvia, Malta
University of Pittsburgh
Merck Sharp & Dohme LLC

Completed

Aprepitant for PONV Prophylaxis in Outpatient Plastic Surgery

Postoperative Nausea and Vomiting

United States
Therapeutic Advances in Childhood Leukemia Consortium
Takeda; Children's Hospital Los Angeles

Active, not recruiting

PO Ixazomib in Combination With Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

Lymphoblastic Leukemia, Acute, Childhood | ALL, Childhood | Lymphoblastic Lymphoma, Childhood

United States, Australia
National Cancer Institute (NCI)

Completed

A Phase I Trial of Tamoxifen and 9-Cis-Retinoic Acid in Breast Cancer Patients

Breast Cancer | Breast Neoplasm

United States
National Cheng-Kung University Hospital
National Science Council, Taiwan

Completed

The Therapeutic Role of Intravenous Albumin Administration for Peptic Ulcer Bleeding Patients With Hypoalbuminemia

Hypoalbuminemia | Peptic Ulcer Bleeding

Taiwan
Clinical Nutrition Research Center, Illinois Institute...
California Strawberry Commission

Completed

Effect of 6-week Strawberry Supplementation on Insulin Action (STR2)

Insulin Resistance | Metabolic Disease | Nutritional Disease

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders

Non-Neoplastic Hematologic and Lymphocytic Disorder

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI); Oregon Health and Science University

Active, not recruiting

Methotrexate, Mannitol, Rituximab, and Carboplatin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma

Central Nervous System Lymphoma

United States
Polish Lymphoma Research Group

Completed

Ofatumumab With IVAC Salvage Chemotherapy in Diffuse Large B Cell Lymphoma Patients (PLRG8)

Diffuse Large B Cell Lymphoma

Poland
Institut Bergonié
Pfizer; Reliable Cancer Therapies

Completed

Metronomic Chemotherapy in Patients With Advanced Solid Tumor With Bone Metastasis and Advanced Pretreated Osteosarcoma (METZOLIMOS)

Osteosarcoma | Solid Tumor

France
ETOP IBCSG Partners Foundation

Terminated

Liposomal Doxorubicin Compared With Observation or Cyclophosphamide and Methotrexate in Treating Older Women Who Have Undergone Surgery for Breast Cancer (CASA)

Breast Cancer

Italy, Australia, Belgium, Switzerland, Slovenia, Hungary, Sweden, New Zealand, Romania
Institute of Cancer Research, United Kingdom

Active, not recruiting

Combination Chemotherapy in Treating Patients With Early Stage Breast Cancer That Has Been Removed By Surgery (TACT2)

Breast Cancer

United Kingdom
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Alemtuzumab, Busulfan, and Cyclophosphamide Followed By a Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer

Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Peripheral Stem Cell Transplant in Treating Patients With Multiple Myeloma

Multiple Myeloma | Plasma Cell Neoplasm

United States
HaEmek Medical Center, Israel
Clalit Health Services

Terminated

Maintenance Metronomic Chemotherapy for Metastatic Colorectal Carcinoma

Colorectal Cancer Metastatic

Israel
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S9920 Busulfan Compared With Cyclophosphamide in Patients Undergoing Total-Body Irradiation Plus Peripheral Stem Cell Transplantation for Advanced Myelodysplastic Syndrome or Related Acute Myeloid Leukemia

Myelodysplastic Syndromes | Leukemia

United States, Canada
Leiden University Medical Center

Unknown

Combination Chemotherapy Compared With Mitoxantrone in Treating Older Patients With Advanced Breast Cancer

Breast Cancer

Netherlands
National Taiwan University Hospital
Chang Gung Memorial Hospital; Taipei Veterans General Hospital, Taiwan; Taichung...

Completed

Bevacizumab With Etoposide and Cisplatin in Breast Cancer Patients With Brain and/or Leptomeningeal Metastasis

Breast Neoplasms | Brain Metastases | Leptomeningeal Metastasis

Taiwan
Kyoto University

Terminated

Gene Expression Profiling in Patients With Invasive Bladder Cancer Receiving Methotrexate, Vinblastine, Doxorubicin, and Cisplatin

Bladder Cancer

Japan
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Stage II Bladder Cancer

Bladder Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute

Completed

Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTX

Mucositis | Graft-versus-host Disease

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Methotrexate, Trimetrexate Glucuronate, and Leucovorin in Treating Patients With Refractory or Recurrent Osteosarcoma

Sarcoma

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients Undergoing Surgery for Newly Diagnosed High-Grade Osteosarcoma

Sarcoma
Oklahoma Medical Research Foundation
Yale University; Columbia University; NYU Langone Health; Piedmont Heart Institute...

Recruiting

Nature of Anifrolumab Impact on Vaccine-Emergent Immunity in SLE (NAIVE)

Systemic Lupus Erythematosus (SLE)

United States
Huashan Hospital

Active, not recruiting

A Dose-escalating Pilot Study of Orelabrutinib for Newly-diagnosed PCNSL (ORMD2021)

Primary Central Nervous System Lymphoma

China
Chinese Academy of Sciences
Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western...

Completed

Acupuncture Study on Rheumatoid Arthritis, Monitoring Microbiome and Blood

Rheumatoid Arthritis

China
Gruppo Italiano Malattie EMatologiche dell'Adulto
Study Alliance Leukemia (SAL) Group

Completed

Phase III Trial in Acute Promyelocytic Leukemia Patients (APL0406)

Leukemia

Germany, Italy, Austria
St. Jude Children's Research Hospital
Cookies for Kids' Cancer

Terminated

Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS)

United States
Southwest Oncology Group
National Cancer Institute (NCI); University of Southern California; NCIC Clinical...

Terminated

4B951, Combination Chemotherapy in Treating Patients With Bladder Cancer

Bladder Cancer

United States, Canada
Singapore General Hospital

Terminated

Leflunomide Versus Sulfasalazine/Methotrexate in Rheumatoid Arthritis:an Ultrasound/Magnetic Resonance Imaging Study

Rheumatoid Arthritis

Singapore
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Acute Promyelocytic Leukemia

Leukemia

United States
University College, London
Cancer Research UK

Completed

Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma

Lymphoma | Mucositis | Neurotoxicity | Chemotherapeutic Agent Toxicity

United Kingdom
Istituto Scientifico Romagnolo per lo Studio e...

Unknown

Cyclophosphamide, Methotrexate, and Fluorouracil, With or Without Epirubicin Hydrochloride, in Treating Women Who Have Undergone Surgery for Breast Cancer (Group III Closed to New Patients as of 12/7/2009)

Breast Cancer
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Cyclophosphamide in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Fanconi's Anemia

Fanconi Anemia

United States, Brazil

Search clinical trials for: Placebo + Methotrexate

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