Search clinical trials for: Placebo of Simvastatin

Total 183200 results

Kurume University

Completed

Detection of Plaque Inflammation by Positron Emission Tomography (PET)-Effects of Simvastatin on Plaque Inflammation

Atherosclerosis

Japan
University of Texas Southwestern Medical Center
Merck Sharp & Dohme LLC; Donald W. Reynolds Foundation

Completed

Comparison of Efficacy and Safety of Ezetimibe or Statin Monotherapy to Co-Administration of Both

Cholesterol, LDL

United States
Organon and Co
Merck Sharp & Dohme LLC

Completed

Comparison of Ezetimibe Added to Ongoing Statin Therapy Versus Doubling the Dose of Statin in the Treatment of Hypercholesterolemia (P04355)

Hypercholesterolemia
Pfizer

Completed

Atorvastatin Versus Simvastatin In The Prevention Of Coronary Heart Disease (CHD) In Patients With Known CHD (IDEAL)

Cardiovascular Diseases

Denmark, Finland, Sweden, Norway, Netherlands, Iceland
Kowa Research Europe

Completed

Follow-on Protocol of Pitavastatin Versus Simvastatin in Patients With Hypercholesterolemia or Dyslipidemia and Coronary Heart Disease Risk Factors

Dyslipidemia | Hypercholesterolemia | Coronary Heart Disease

Spain, Sweden, Denmark, Netherlands
Solvay Pharmaceuticals

Completed

Comparison of the Combination of Fenofibrate and 20 mg Simvastatin Versus 40 mg Simvastatin Monotherapy

Hyperlipidemia

Czech Republic, Denmark, France, Germany, Hungary, Netherlands, Poland, Ukraine
AstraZeneca

Completed

Study To Assess the Pharmacokinetics of AZD1656 During Coadministration With Simvastatin

Type 2 Diabetes Mellitus

United States
Rockefeller University
Cornell University; Adelphi University

Terminated

Quality of Life in Patients With Statin-Associated Myopathy

Statin Adverse Reaction

United States
Merck Sharp & Dohme LLC

Terminated

A Study of the Efficacy and Safety of MK-0431D (a Fixed-dose Combination of Sitagliptin and Simvastatin) for the Treatment of Participants With Type 2 Diabetes Mellitus (T2DM) With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-266)

Type 2 Diabetes Mellitus
The University of Hong Kong

Enrolling by invitation

Statin and Bone Health

Diabetes Mellitus, Type 2

Hong Kong
Organon and Co
Merck Sharp & Dohme LLC

Completed

Ezetimibe Plus Simvastatin Versus Simvastatin Alone in African-American Subjects With Primary Hypercholesterolemia (P03377)

Atherosclerosis | Hypercholesterolemia
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Cardiovascular Events Based On Statin Initiation In The Elderly

Dyslipidemia | Cardiovascular
Solvay Pharmaceuticals

Completed

Comparison of the Combination of Fenofibrate and Simvastatin Versus Pravastatin

Hyperlipidemia

Greece, Israel, Romania, Russian Federation, South Africa
Solvay Pharmaceuticals

Completed

Comparison of the Combination of Fenofibrate and Simvastatin Versus Atorvastatin

Hyperlipidemia

Bulgaria, Czech Republic, Germany, Slovakia, Ukraine
Imperial College London

Completed

Investigation of Simvastatin in Secondary Progressive Multiple Sclerosis (MS-STAT)

Secondary Progressive Multiple Sclerosis

United Kingdom
University of Wisconsin, Madison
National Institute on Aging (NIA)

Completed

Statin Effects on Beta-Amyloid and Cerebral Perfusion in Adults at Risk for Alzheimer's Disease (SHARP)

Alzheimer's Disease

United States
John Harris

Completed

Clinical Trial of Simvastatin to Treat Generalized Vitiligo

Vitiligo

United States
University of Oklahoma
US Department of Veterans Affairs

Withdrawn

Simvastatin Effect on the Incidence of Acute Lung Injury/Adult Respiratory Distress Syndrome (ALI/ARDS)

Acute Lung Injury | Adult Respiratory Distress Syndrome

United States
University of East Anglia

Unknown

Simvastatin in Chronic Obstructive Pulmonary Disease (COPD)

Emphysema | COPD

United Kingdom
Hospital Clinic of Barcelona

Completed

Efficacy and Safety of Simvastatin in the Treatment of Portal Hypertension

Cirrhosis | Portal Hypertension

Spain
Organon and Co

Completed

A Study of SCH 58235 (Ezetimibe) When Added to Ongoing Therapy With a Statin in Participants With Primary Hypercholesterolemia, Known Coronary Heart Disease, or Multiple Cardiovascular Risk Factors (P02173)

Primary Hypercholesterolemia
Samsung Medical Center

Unknown

Capecitabine Plus Simvastatin in Locally Advanced Rectal Cancer Patients

Adenocarcinoma of Rectum

Korea, Republic of
Chinese PLA General Hospital

Unknown

The Effect of Simvastatin Combined With Ezetimibe in Patients With Stable Angina and Diabetes

Coronary Heart Disease

China
GlaxoSmithKline

Completed

Evaluation of Efficacy and Safety of Combined Omacor (Omega-3-acid Ethyl Esters) and Simvastatin Therapy in Hypertriglyceridemic Subjects (COMBOS)

Hypertriglyceridemia
Akron Children's Hospital
Cystic Fibrosis Foundation

Completed

Effect of Simvastatin on CF Airway Inflammation

Cystic Fibrosis

United States
Solvay Pharmaceuticals

Completed

Comparison of the Combination of Fenofibrate and 40 mg Simvastatin Versus 40 mg Simvastatin Monotherapy

Cardiovascular Diseases

Australia, Estonia, Hungary, Latvia, Lithuania, New Zealand
Organon and Co

Completed

Ezetimibe/Simvastatin (10 mg/40 mg) vs. the Doubling of Atorvastatin in High Risk Participants (MK-0653A-134 AM1)(COMPLETED)

Hypercholesterolemia
Organon and Co

Completed

Begin With The Right Patients With Dual-Inhibition Action Therapy Through Vytorin for Newly Diagnosed Dyslipidemia Patients (0653A-172)(COMPLETED) (BRAVO)

Hypercholesterolemia
University of Virginia
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Comprehensive Magnetic Resonance of Peripheral Arterial Disease

Peripheral Artery Disease

United States
Gachon University Gil Medical Center

Completed

Differential Metabolic Effects of Statins

Hypercholesterolemia

Korea, Republic of
University of Cologne
German Federal Ministry of Education and Research

Completed

Statin Recapture Therapy Before Coronary Artery Bypass Grafting (StaRT-CABG)

Coronary Artery Disease

Germany
Ain Shams University

Completed

Simvastatin Around Immediate Implant

Bone Regeneration | Alveolar Bone Resorption | Immediate Implant Placement
Queen's University, Belfast
Belfast Health and Social Care Trust

Withdrawn

Targeting Microvascular Dysfunction in Young Hypertensive Patients

Hypertension

United Kingdom
University College, London

Unknown

Use of Simvastatin as a Steroid Sparing Agent for Uveitis Patients

Uveitis

United Kingdom
Rigshospitalet, Denmark
Klinisk Biokemisk Afdeling; Klinisk farmakologisk Afdeling; Sektion for Biomedicin...

Completed

SIMOX - Induction of Oxidative Stress (SIMOX)

Oxidative Stress

Denmark
Organon and Co

Completed

An Extension Study of An Investigational Drug in Patients With Hypercholesterolemia (0653A-038)(COMPLETED)

Hypercholesterolemia
University Hospital, Toulouse

Completed

Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan Syndrome (RASTAT)

Noonan Syndrome

France
University College, London
London School of Hygiene and Tropical Medicine; The Leeds Teaching Hospitals... and other collaborators

Active, not recruiting

Multiple Sclerosis-Simvastatin Trial 2 (MS-STAT2)

Secondary Progressive Multiple Sclerosis (SPMS)

United Kingdom
Gachon University Gil Medical Center

Completed

Vascular and Metabolic Effects of Vytorin

Hypercholesterolemia

Korea, Republic of
Hospital Universitari Son Dureta
Fundació d'investigació Sanitària de les Illes Balears; Cimera

Completed

Efficacy of Simvastatin for the Treatment of COPD

Chronic Obstructive Pulmonary Disease

Spain
University of British Columbia

Withdrawn

Statins To Treat Adult Cystic Fibrosis (CFStatin)

Cystic Fibrosis | Systemic Inflammation
Santa Casa de Porto Alegre

Completed

Simvastatin for Treating Erectile Dysfunction (STED)

Erectile Dysfunction | C Reactive Protein | Vascular Disease Detected
Complexa, Inc.

Completed

A Study of the PK Interaction of CXA-10 With Pravastatin and Vytorin® in Healthy Males (DDI)

Acute Kidney Injury

United States
Merck Sharp & Dohme LLC

Completed

Lipid Efficacy Study (0524B-022)(COMPLETED)

Primary Hypercholesterolemia | Mixed Hyperlipidemia
NeuroBo Pharmaceuticals Inc.

Completed

Effect of Gemcabene on the Pharmacokinetics of Simvastatin in Healthy Volunteers

Hypercholesterolemia
Assiut University

Unknown

Role of Simvastatin in Relapsing-Remitting Multiple Sclerosis

Simvastatin Multiple Sclerosis
Bronx VA Medical Center

Completed

Comparison of the Effect of Vytorin 10/80 Tablet Split Into 4 and Simvastatin 20 Milligrams on Low-density Lipoprotein (LDL) Cholesterol

Hypercholesterolemia

United States
Seattle Institute for Biomedical and Clinical Research

Completed

Do HMG CoA Reductase Inhibitors Affect Abeta Levels?

Aging | Alzheimer's Disease

United States
Kowa Research Europe

Completed

Study to Compare the Efficacy and Safety of Pitavastatin and Simvastatin

Dyslipidemia | Hypercholesterolemia

Spain, Sweden, Denmark, Netherlands
Organon and Co

Completed

A Study to Evaluate an Investigational Drug in Patients With Mixed Hyperlipidemia (0653A-071)(COMPLETED)

Hypercholesterolemia | Hypertriglyceridemia | Hyperlipidemia

Search clinical trials for: Placebo of Simvastatin

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