Search clinical trials for: Placebo to BI 135585

Total 1461 results

Gilead Sciences
AstraZeneca

Terminated

Enoximone Plus Extended-Release Metoprolol Succinate in Subjects With Advanced Chronic Heart Failure

Heart Failure, Congestive

United States
Novartis

Completed

26 Week Efficacy, Safety and Tolerability Study of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Lung Diseases, Obstructive | Pulmonary Disease, Chronic Obstructive | COPD

United States, Germany, Spain, Argentina, Italy, Turkey, Canada, India, Sweden, Korea, Republic of, Taiwan, Puerto Rico
AbbVie

Completed

A Study to Compare Upadacitinib (ABT-494) Monotherapy to Methotrexate (MTX) Monotherapy in Adults With Rheumatoid Arthritis (RA) Who Have Not Previously Taken Methotrexate (SELECT-EARLY)

Rheumatoid Arthritis

United States, Argentina, Australia, Belarus, Belgium, Bosnia and Herzegovina, Brazil, Bulgaria, Canada, Chile, China, Colombia, Croatia, Czechia, Estonia, Germany, Greece, Guatemala, Hong Kong, Hungary, Ireland, Israel, Italy, Japan, K... and more
Organon and Co

Completed

Study of Montelukast and Its Effect on Lower Leg Growth in Children With Asthma (MK-0476-254)

Asthma, Bronchial
AbbVie (prior sponsor, Abbott)

Completed

A Double Blind Study in Pediatric Subjects With Chronic Plaque Psoriasis, Studying Adalimumab vs. Methotrexate

Plaque Psoriasis
Hoffmann-La Roche

Terminated

A Study of RoActemra/Actemra (Tocilizumab) Versus Adalimumab in Combination With Methotrexate (MTX) in Patients With Moderate to Severe Active Rheumatoid Arthritis And an Inadequate Response to Treatment With Only One Tumor Necrosis Factor (TNF)-Inhibitor

Rheumatoid Arthritis

Germany, Italy, Spain, United States, France, Sweden, Greece, Russian Federation, Denmark, Finland, Netherlands, Puerto Rico
State University of New York at Buffalo
Juvenile Diabetes Research Foundation; University of Glasgow

Recruiting

Triple Therapy in T1DM

Type 1 Diabetes Mellitus

United States
Intercept Pharmaceuticals

Completed

Study Evaluating the Efficacy and Safety of Obeticholic Acid in Subjects With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (REVERSE)

Nonalcoholic Steatohepatitis | Compensated Cirrhosis

United States, Spain, France, Australia, New Zealand, Puerto Rico, Germany, Canada, United Kingdom, Hungary, Poland, Ukraine
Merck Sharp & Dohme LLC

Terminated

A Study of Adavosertib (MK-1775) in Combination With Topotecan/Cisplatin in Participants With Cervical Cancer (MK-1775-008)

Cervical Cancer
Theracos

Completed

Safety and Efficacy Study of EGT0001442 in Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus Type 2

United States, Canada
Instituto Nacional de Ciencias Medicas y Nutricion...

Unknown

Effects of Cholecalciferol on Osteoprotegerin Levels in Patients on Peritoneal Dialysis

Renal Insufficiency | Vitamin D Deficiency | End Stage Renal Failure on Dialysis | Vascular Calcification

Mexico
G & W Laboratories Inc.

Completed

Safety and Efficacy Study of Anucort HC TM 25mg Rectal Suppositories to Treat Symptomatic Internal Hemorrhoids

Internal Hemorrhoids

United States
University Hospital, Ghent

Completed

Does it Make Sense to Give Postoperative Antibiotics to Patients With an Uncomplicated Acute Cholecystitis

Uncomplicated Acute Cholecystitis

Belgium, Qatar
Hoffmann-La Roche

Completed

Study to Compare the Efficacy of Tocilizumab With or Without Glucocorticoid Discontinuation in Rheumatoid Arthritis Participants

Rheumatoid Arthritis

Serbia, Germany, France, Russian Federation, Italy, Tunisia
Merck Sharp & Dohme LLC

Completed

A Study of Safety and Efficacy of Vaniprevir Administered With Pegylated-Interferon and Ribavirin in Japanese Participants With Chronic Hepatitis C Infection (7009-016)

Hepatitis C
University of Aarhus
Aarhus University Hospital; ADS AIPHIA Development Services AG

Terminated

Refractory Ascites in Patients With Liver Cirrhosis, and the Potential Treatment With 48 Hours Infusion of Ularitide. (ULA04)

Cirrhosis, Liver | Ascites Hepatic

Denmark
Manchester University NHS Foundation Trust
Bayer; University of Manchester

Completed

Study of The Effects of Testosterone in Frail Elderly Men

Frailty | Sarcopenia

United Kingdom
Wake Forest University Health Sciences

Active, not recruiting

Study of Nasal Insulin to Fight Forgetfulness - Device Study

Cognitive Impairment | Mild Cognitive Impairment

United States
Merck Sharp & Dohme LLC

Terminated

Efficacy & Safety of Infliximab Monotherapy Vs Combination Therapy Vs AZA Monotherapy in Ulcerative Colitis (Part 1) Maintenance Vs Intermittent Therapy for Maintaining Remission (Part 2)(Study P04807)

Ulcerative Colitis
Boehringer Ingelheim
Eli Lilly and Company

Completed

Safety and Efficacy of Empagliflozin (BI 10773) and Sitagliptin Versus Placebo Over 76 Weeks in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Belgium, Canada, China, France, Germany, Greece, India, Ireland, Japan, Korea, Republic of, Mexico, Philippines, Slovakia, Slovenia, Switzerland, Taiwan, Turkey, Ukraine
Boehringer Ingelheim

Completed

BI 10773 add-on to Metformin in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

United States, Argentina, Austria, Czech Republic, Estonia, Finland, France, Germany, Hungary, Latvia, Norway, Romania, Russian Federation, Slovakia, Spain, Ukraine
Boehringer Ingelheim

Completed

Study to Investigate Safety and Tolerability of BI 1744 CL in Free Dose Combination With Tiotropium Bromide Both Administered by Respimat® in Healthy Male Volunteers

Healthy
Merck Sharp & Dohme LLC

Completed

Vaniprevir Administered With Pegylated-interferon and Ribavirin in Japanese Treatment-Naïve Chronic Hepatitis C Participants (MK-7009-043)

Hepatitis C, Chronic
Engelhard Arzneimittel GmbH & Co.KG

Completed

Tyrosur® Gel-Investigation on Wound Healing Efficacy

Wound Healing | Wounds
RWTH Aachen University

Terminated

Diastolic Dysfunction in Patients With Type 2 Diabetes Mellitus (Diast Dysfkt)

Diabetes Mellitus Type 2 (T2DM) | Left Ventricular Diastolic Dysfunction

Germany
Boehringer Ingelheim

Completed

Characterization of 24 Hour Spirometry Profiles of Inhaled BI 1744 CL and Inhaled Foradil in Patients With Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

A Multiple Dose Study Of Ertugliflozin (PF-04971729, MK-8835) In Otherwise Healthy Overweight And Obese Volunteers (MK-8835-037)

Healthy Volunteer
Yungjin Pharm. Co., Ltd.

Terminated

Therapeutic Exploratory Phase 2 Study to Evaluate the Safety and Efficacy of MB12066 in Patients With Nonalcoholic Fatty Liver Disease(NAFLD) Except Cirrhosis

Nonalcoholic Fatty Liver Disease

Korea, Republic of
Takeda

Completed

Azilsartan Medoxomil (TAK-491) Compared to Placebo in Korean Adults With Hypertension

Hypertension

Korea, Republic of
Organon and Co

Completed

A Study to Investigate the Efficacy and Safety of a Single Injection of Corifollitropin Alfa (Organon 36286) for Ovarian Stimulation Using Daily Recombinant Follicle Stimulating Hormone (FSH) as Reference (P05787)

In Vitro Fertilization
Organon and Co

Withdrawn

A Study of Montelukast (MK-0476) Compared With Fluticasone in Pediatric Participants With Chronic Asthma (MK-0476-303)

Asthma, Bronchial
Wockhardt

Completed

Evaluate the Effect of WCK 5222 on the QT/QTc Interval in Healthy Volunteers

QT/QTc Interval in Healthy Volunteers

United States
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety and Efficacy of Sitagliptin 100 mg in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control (MK-0431-229)

Type 2 Diabetes Mellitus
Merck Sharp & Dohme LLC

Completed

Reproducibility and Comparison of Platelet Function Assays With Aspirin and Clopidogrel (MK-0000-167)

Healthy Volunteers
Finnish Institute for Health and Welfare

Unknown

Effects of Intranasal Naloxone on Gambling Urges and Craving in Gambling Disorder (NalGamb)

Naloxone | Gambling Disorder | Opioid Antagonist | Pathological Gambling

Finland
Bezmialem Vakif University

Completed

Effect of Dill in Thyroiditis and Nodular Goiter Patients (Dill)

Thyroid Nodule

Turkey
Institut du Cancer de Montpellier - Val d'Aurelle

Terminated

A Comparative Study of Pravastatin vs Placebo as Primary Prevention of Severe Subcutaneous Breast Fibrosis in Hyper-radiosensitive Identified Patients With Breast Cancer (PRAVAPREV-01)

Breast Cancer

Monaco, France
Merck Sharp & Dohme LLC

Completed

Reversal of Neuromuscular Blockade With Sugammadex or Usual Care in Hip Fracture Surgery or Joint (Hip/Knee) Replacement (P07038)

Arthroplasty, Replacement, Knee | Neuromuscular Blockade | Arthroplasty, Replacement, Hip | Blood Coagulation | Antithrombotic Agents
Novartis Pharmaceuticals

Completed

A Study to Evaluate the Effect of LCZ696 on Aortic Stiffness in Subjects With Hypertension

Hypertension

Germany, Switzerland, United Kingdom
Gilead Sciences

Completed

Safety and Efficacy of Switching From Dolutegravir and ABC/3TC or ABC/DTG/3TC to B/F/TAF in HIV-1 Infected Adults Who Are Virologically Suppressed

HIV-1 Infection

Spain, United States, France, Italy, Germany, Canada, United Kingdom, Belgium, Puerto Rico, Australia
Aswan University Hospital

Completed

Role of Dexamethasone for Erector Spinae Plane Block in Patients Undergoing Total Abdominal Hysterectomy

Postoperative Pain

Egypt
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effects of Single-dose Seltorexant on Electrocardiogram Intervals in Healthy Adult Participants

Healthy

Belgium
Janssen Research & Development, LLC

Completed

Study to Assess the Effects of Esketamine on Safety of On-road Driving in Healthy Participants (DRiVESaFe)

Healthy

Netherlands
FibroGen

Terminated

Trial of Pamrevlumab (FG-3019), in Non-Ambulatory Participants With Duchenne Muscular Dystrophy (DMD) (MISSION)

Duchenne Muscular Dystrophy

United States
University Hospital, Basel, Switzerland

Active, not recruiting

Empagliflozin and Anakinra for the Treatment of Postprandial Hypoglycemia in Patients With Prediabetes (Hypo-PrEA)

Postprandial Hypoglycemia

Switzerland
Chinese University of Hong Kong

Active, not recruiting

A Randomized, Controlled Trial of Probiotic and Peanut Oral Immunotherapy (PPOIT) in Inducing Tolerance in Hong Kong Children With Peanut Allergy Compared With Oral Immunotherapy (OIT) Alone and With Placebo

Peanut Allergy | Food Allergy in Children

Hong Kong
Jacobus Pharmaceutical

Completed

Effectiveness of 3,4-Diaminopyridine in Lambert-Eaton Myasthenic Syndrome (DAPPER)

Lambert-Eaton Myasthenic Syndrome | Eaton-Lambert Myasthenic Syndrome

United States
Jordan D. Miller, Ph.D.
National Center for Research Resources (NCRR); National Center for Advancing... and other collaborators

Completed

Safety of Ataciguat in Patients With Moderate Calcific Aortic Valve Stenosis

Aortic Valve Stenosis

United States
Cytokinetics

Recruiting

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM (MAPLE-HCM)

Obstructive Hypertrophic Cardiomyopathy (oHCM)

United States, Denmark, Spain, Netherlands, United Kingdom, France, China, Israel, Germany, Italy, Hungary, Canada
Tris Pharma, Inc.
Forest Laboratories

Completed

Evaluation of the Effects of Multiple Doses of Cebranopadol on the Electrical Activity of the Heart in Healthy Subjects

Prolonged QTc Interval | Pharmacokinetic

United States

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